Browsing by Author "Bakkaloglu, S"

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    Reno-vascular hypertension in childhood: a nationwide survey
    Bayazit, AK; Yalcinkaya, F; Cakar, N; Duzova, A; Bircan, Z; Bakkaloglu, A; Canpolat, N; Kara, N; Sirin, A; Ekim, M; Oner, A; Akman, S; Mir, S; Baskin, E; Poyrazoglu, HM; Noyan, A; Akil, I; Bakkaloglu, S; Soylu, A
    Renovascular disease accounts for 8-10% of all cases of paediatric hypertension, whereas, in adults, its incidence is approximately 1%. The Turkish Paediatric Hypertension Group aimed to create the first registry database for childhood renovascular hypertension in Turkey. Twenty of the 28 paediatric nephrology centres in Turkey responded to the survey and reported 45 patients (27 girls, 18 boys) with renovascular hypertension between 1990 and 2005. The age at presentation ranged from 20 days to 17 years. The mean blood pressure at the diagnosis was 169/110 mmHg. Chief complaints of symptomatic patients were headache (38%), seizure (18%), epistaxis (4%), growth retardation (4%), cognitive dysfunction (4%), polyuria (2%), palpitation (2%), and hemiplegia (2%). Renovascular hypertension was found incidentally in 11 children. The diagnosis of renovascular hypertension was established with conventional angiography in 39 patients, MR angiography in three, CT angiography in two, and captopril diethylene triamine penta-acetic acid (DTPA) scintigraphy in one patient. Twenty-one children had bilateral renal artery stenosis and 24 had unilateral renal artery stenosis. Of these, 14 (31%) had fibromuscular dysplasia; 12 (27%) Takayasu's arteritis; six (13%) neurofibromatosis; two (5%) Williams syndrome; one (2%) Kawasaki disease; one (2%) mid-aortic syndrome; one (2%) extrinsic compression to the renal artery, and eight (18%) unspecified bilateral renal artery stenosis. Hypertension was controlled with antihypertensive drugs in 17 patients. Percutaneous transluminal angioplasty (PTRA) or surgery had to be performed in 28 patients: PTRA in 16 patients, PTRA + surgery in one patient and surgery in 11 patients (four nephrectomies). The importance of vasculitic disease, especially Takayasu's arteritis, should not be underestimated in children with renovascular hypertension.
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    Renovascular hypertension in childhood: A nation-wide survey
    Bayazit, AK; Yalcinkaya, F; Cakar, N; Duzova, A; Bircan, Z; Aslan, S; Bakkaloglu, A; Canpolat, N; Kara, N; Sirin, A; Ekim, M; Oner, A; Akman, S; Mir, S; Baskin, E; Poyrazoglu, H; Noyan, A; Akil, I; Bakkaloglu, S; Soylu, A
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    THE ROLE OF ANTIMICROBIAL POLYPEPTIDES FOR THE PREDICTING OF URINARY TRACT INFECTION: UTILISE STUDY
    Yildirim, ZY; Afonso, AC; Akil, I; Aksu, B; Alpay, H; Atmis, B; Aydog, O; Bakkaloglu, S; Bayazit, AK; Bayram, MT; Bilge, I; Bulut, IK; Comak, E; Kasap-Demir, B; Delebe, OC
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    TURKISH SOCIETY OF PEDIATRIC NEPHROLOGY - FEBRUARY 6TH EARTHQUAKES DISASTER MANAGEMENT
    Bakkaloglu, S; Yavascan, Ö; Yilmaz, A; Gulleroglu, K; Kasap-Demir, B; Ertan, P; Poyrazoglu, H
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    CLINICAL, EPIDEMIOLOGICAL AND PROGNOSTIC FEATURES OF CHILDREN WITH HEMOLYTIC UREMIC SYNDROME: MULTICENTER EXPERIENCE OF TURKEY
    Ertan, P; Bulut, IK; Guven, S; Cicek, N; Tulpar, S; Coskun, S; Donmez, O; Dusunsel, R; Serdaroglu, E; Bek, K; Kucuk, N; Akinci, N; Celakil, ME; Dursun, I; Yigit, G; Soylu, A; Bayram, MT; Bayrakci, US; Bakkaloglu, S; Ozdogan, EB; Koyun, M; Tufan, AK; Sonmez, F; Delibas, A; Tabel, Y; Ozkayin, N; Melek, E; Erdogan, H; Uysal, B; Bastug, F; Yavascan, O
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    The relationship between urine heat shock protein 70 and congenital anomalies of the kidney and urinary tract: UTILISE study
    Aksu, B; Afonso, AC; Akil, I; Alpay, H; Atmis, B; Aydog, O; Bakkaloglu, S; Bayazit, AK; Bayram, MT; Bilge, I; Bulut, IK; Cetinkaya, APG; Comak, E; Demir, BK; Dincel, N; Donmez, O; Durmus, MA; Dursun, H; Dusunsel, R; Duzova, A; Ertan, P; Gedikbasi, A; Goknar, N; Guven, S; Hacihamdioglu, D; Jankauskiene, A; Kalyoncu, M; Kavukcu, S; Kenan, BU; Kucuk, N; Kural, B; Litwin, M; Montini, G; Morello, W; Obrycki, L; Omer, B; Ozdemir, EM; Ozkayin, N; Paripovic, D; Pehlivanoglu, C; Saygili, S; Schaefer, F; Schaefer, S; Sonmez, F; Tabel, Y; Tas, N; Tasdemir, M; Teixeira, A; Tekcan, D; Topaloglu, R; Tulpar, S; Turkkan, ON; Uysal, B; Uysalol, M; Vitkevic, R; Yavuz, S; Yel, S; Yildirim, T; Yildirim, ZY; Yildiz, N; Yuksel, S; Yurtseven, E; Yilmaz, A
    Background: Congenital anomalies of the kidney and urinary tract (CAKUT) are defined as structural malformations of the kidney and/or urinary tract. Heat shock proteins (HSPs) are expressed in the kidney in response to cellular changes, such as thermal, hemodynamic, osmotic, inflammatory, and mechanical stresses. This study aimed to assess uHSP70 levels during acute urinary tract infections (UTI) and non-infection periods in patients with CAKUT, and to evaluate whether uHSP70 is elevated in CAKUT subtypes. Methods: Among patients with CAKUT, 89 patients with UTI (CAKUT-A), 111 without UTI (CAKUT-B), and 74 healthy children were included in the study. uHSP70 levels were measured using enzyme-linked immunosorbent assay (ELISA). Results: uHSP70 level was significantly higher in the CAKUT-A group than in the CAKUT-B and healthy control groups (p < 0.0001). Moreover, the level of uHSP70 was significantly higher in the CAKUT-B group than in the control group (p < 0.0001), but was not different between the CAKUT subtypes (p > 0.05). Conclusion: Urine HSP70 can also be used to predict UTI in patients with CAKUT. Moreover, uHSP70 levels were higher in children with CAKUT during the non-infectious period than in healthy controls. This suggests that children with CAKUT are at risk of chronic non-infectious damage.