Browsing by Author "Baykal S."
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Item Clear cell meningioma: Case report and literature review(Churchill Livingstone, 2003) Kuzeyli K.; Çakir E.; Usul H.; Karaarslan G.; Reis A.K.; Temiz C.; Baykal S.The clear cell meningioma is rare and a recently described histologic variant of meningioma. The most interesting aspect of clear cell meningioma is the high recurrence rate and agressiveness. Until now 17 intracranial clear cell meningioma cases had been reported in the English language literature. We present 2 new cases of clear cell meningioma which is discussed with the relevant literature. © 2003 Elsevier Science Ltd. All rights reserved.Item Drug-refractory irritability and related factors in autistic children(Taylor and Francis Ltd., 2024) Aykutlu H.C.; Bozatlı L.; Görker I.; Okyar E.; Uzun-Çiçek A.; Ucuz İ.; Doğru H.; Baykal S.; Bilaç Ö.; Arslan E.N.; Yıldız N.; Alnak A.; Turnalı N.; Sobay N.S.Objectives: Autistic children frequently exhibit irritability, which can manifest as aggression, self-injurious behaviour, and severe tantrums, leading to significant impairments. Two atypical antipsychotics have been licensed by the Food and Drug Administration for the treatment of irritability in autistic children, although a significant percentage of these children do not respond to this treatment. This study aimed to determine the frequency of drug refractory irritability (DRI) and identify the risk factors in a large clinical sample of autistic children. Methods: The medical records of 1279 children aged 2–18 years diagnosed with autism and undergoing clinical follow-up were retrospectively analysed. Socioeconomic and clinical characteristics, co-occurring psychiatric disorders and physical conditions were recorded. Results: 55% of the sample used antipsychotics to treat irritability, and 8.2% met the DRI criteria. Older age, severe support requirement for autism, language impairment, anxiety disorders, sleep difficulties, gastrointestinal system, and dental problems were found to significantly increase the risk of DRI. Conclusion: Our findings indicate that a significant proportion of the clinical sample of autistic children had DRI. The physical, psychiatric, and environmental risk factors identified in our study also highlight heterogeneity in the etiology of DRI. Further research on DRI is needed to develop treatment and prevention strategies. © 2024 The British Society of Developmental Disabilities.