Browsing by Author "Bayrak Degirmenci, P"

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    Improvement in sleep quality with allergen-spesific immunotherapy in patients with allergic rhinitis
    Bayrak Degirmenci, P; Kirmaz, C; Deveci, A; Yüksel, H; Yilmaz, Ö
    Objective: In the medical literature, it has been shown that quality of life and sleep quality are impaired due to allergic rhinitis and are improved with treatment. In this study, we aimed to determine the change in sleep quality of patients with allergic rhinitis using allergen-specific immunotherapy. Materials and Methods: Seventy-four patients diagnosed with allergic rhinitis according to the clinical evaluation and skin prick test findings in Celal Bayar University Allergy-Immunology Outpatient Department were enrolled in our study. Sleep quality was evaluated with Pittsburgh Sleep Quality Index (PSQI) just before specific immunotherapy was initiated and at the end of the first year of treatment with specific immunotherapy. Results: Frequency of having healthy sleep increased significantly after specific immunotherapy in the patients (p<0.001). A significant correlation was detected between the changes in symptom score and PSQI when evaluated with Spearman correlation analysis (p= 0.01). Improvement was demonstrated in subjective sleep quality, sleep latency, sleep duration, sleep efficacy, factors influencing sleep, use of hypnotics, and daytime somnolence parameters of the PSQI with a decrease in symptom score. Conclusion: In our study, chronic sleep disorder disappeared and improvement in sleep quality was detected in most patients during the second evaluation one year after initiation of specific immunotherapy. Sleep quality increased as the symptom score decreased. These findings demonstrated improvement in the patients' sleep quality with improvement in symptoms following specific immunotherapy treatment. These data should be supported with longer specific immunotherapy therapy in patients with allergic rhinitis.
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    Chronic Urticaria
    Bayrak Degirmenci, P
    Chronic urticaria (CU) is defined as urticaria present continuously or intermittently (present on most days of the week) for at least 6 weeks. Urticaria, more commonly known as hives, is a prevalent disorder that affects between 15 and 25% of the population at some point during their lifetimes. In the last years, urticaria has increasingly attracted notice to clinicians and researchers. However, the pathogenesis is incompletely understood. This review summarizes current guidelines for the management and novel insights in the pathogenesis of urticaria.
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    Our results on SF-36 quality of life scale in patients diagnosed with drug allergy
    Bilgir, F; Bayrak Degirmenci, P; Özgül, RB; Dede, B; Kirmaz, C
    Objective: Drug allergies are drug-hypersensitivity reactions that are assumed to be seen frequently in practice and affect quality of life considerably. The aim of this study is to investigate the effect of drug-allergy on quality of life. Materials and Methods: A total of 100 patients, between 18-70 years of age, who referred to our center with drug allergy were evaluated prospectively. During assessment of patients, a questionnaire including socio-demographic characteristics and a Short Form-36 (SF-36) Quality of Life Scale were used. Results: Of our patients 76% were women, 24% were males and mean age was 38.56 +/- 11.03 years. The physical, social and emotional role components of SF-36 were found to be decreased in all areas in women. When the score dispersion of quality of life subscale according to education level was examined, the physical function subscale was found lower only in elementary school and lesser education areas. Conclusion: In present study it was observed that drug allergy had affected the quality of life of both genders; however its influence over women was more prominent.