Browsing by Author "Bayram M."

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    Importance of inhaler device use status in the control of asthma in adults: The asthma inhaler treatment study
    (2014) Yildiz F.; Erbagci A.; Demirel Y.S.; Akcali S.D.; Ekici A.; Dursunoglu N.; Ediger D.; Erdinc M.; Cemri S.C.; Kalyoncu A.F.; Guclu S.Z.; Aktogu S.; Bayram G.B.; Bayram M.; Akgun M.; Mirici A.; Akyildiz L.; Celik P.; Guven A.O.; Camsari G.; Ozseker F.; Cimen F.; Kurutepe M.; Senyigit A.; Bektas Y.; Ozbudak O.; Saylan B.; Baslilar S.; Polatli M.; Cagatay T.; Kalkan S.; Ozer A.
    BACKGROUND: Proper education and training in correct inhalation technique has been reported to have a substantial role in the achievement of optimal therapeutic benefit and asthma control. The present study was designed to evaluate inhaler technique and the role of education in relation to asthma control among patients with persistent asthma in Turkey. METHODS: A total of 572 patients with persistent asthma (mean ± SD age 42.7 ± 12.2 y, 76% females) were included in this non-interventional, observational, registry study conducted across Turkey. Data on the effective and correct use of inhaler devices were collected via the Ease of Use for the Inhaler Device Questionnaire to patients and physicians. RESULTS: Asthma control (overall 61.5% at baseline, and increased to 87.3% during follow-up) was better, with significant improvement in technique and decrease in basic errors to the range 0-1, regardless of the inhaler type. Overall, the most common basic error associated with inhalation maneuvers was failure to exhale before inhaling through the device (18.9%). There was concordance between the patients and physicians in the ratio of correct inhaler technique only for spray-type inhalers. CONCLUSIONS: Close follow-up with repeated checking of the patient's inhaler technique and correction of errors each time by a physician seem to be associated with a significant decrease in the percent of patients who make basic errors in inhalation maneuvers and device-independent errors, and with better control of persistent asthma. © 2014 Daedalus Enterprises.
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    Comparison of blood carbonic anhydrase activity of athletes performing interval and continuous running exercise at high altitude
    (Taylor and Francis Ltd, 2019) Tas M.; Senturk E.; Ekinci D.; Demirdag R.; Comakli V.; Bayram M.; Akyuz M.; Senturk M.; Supuran C.T.
    The effects of high-intensity interval and continuous exercise on erythrocytes carbonic anhydrase (CA, EC 4.2.1.1) activity levels were scarcely investigated up until now. Here we present a study focused on the CA activity from erythrocytes of athletes experiencing interval and continuous training for 6 weeks, during cold weather and at high altitude (> 1600 m). We observed a 50% increase in the blood CA activity at the second week after initiation of the training in both interval and continuos running groups, whereas the control group did not experience any variation in the enzyme activity levels. In the trained individuals a mild decrease in their body mass, BMI and an increased (Formula presented.) were also observed. The CA activity returned at the basal values after 4–6 weeks after the training started, probably proving that a metabolic compensation occurred without the need of an enhanced enzyme activity. The unexpected 50% rise of activity for an enzyme which acts as a very efficient catalyst for CO2 hydration/bicarbonate dehydration, such as the blood CA, deserves further investigations for better understanding the physiologic basis of this phenomenon. © 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
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    Guideline on pregnancy and diabetes by the society of specialists in perinatology (PUDER), Turkey
    (Ortadog u Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2020) Bayram M.; Asyali Biri A.; Esim Büyükbayrak E.; Daglar H.K.; Ercan F.; Gürsoy Erzincan S.; Çorbacioglu Esmer A.; Inan C.; Kanit H.; Kara Ö.; Katlan D.C.; Nas T.; Öcal E.; Sagsöz N.; Sanhal C.Y.; Sahin G.; Timur H.; Turhan U.; Gençosmanoglu Türkmen G.; Türkyilmaz G.; Bilgin Yanik F.F.; Yüksel M.A.
    Diabetes mellitus (DM) is the most common endocrinologic problem in pregnancy. In Turkey, the reported prevalance is between 1.9-27.9%, with an average of 7.7%. While some of these cases are pregestational diabetes (PGDM), about 90% are detected during the pregnancy for the first time and diagnosed as gestational diabetes (GDM). Diabetes in pregnancy confers serious risks regarding the fetus, newborn and the mother. Therefore, we offer GDM screening for all pregnant women preferantially between 24-28 weeks of gestation. Either one-step 75-g oral glucose tolerance test (OGTT) or two-step 50-g glucose challenge test and 100-g OGTT may be used for the screening and diagnosis. In pregnancies with high-risk for DM, screening should be performed earlier, if possible, in the first antenatal visit. When GDM is diagnosed, maternal glycemic control is tried to be achieved by diet and exercise program, and if necessary, by using insulin. The use of metformin or glyburide in pregnancy is also possible. In women with the diagnosis of DM before pregnancy, preconceptional control of plasma glucose levels is of utmost importance in order to prevent adverse pregnancy outcomes. In pregnancies with GDM regulated by diet and exercise, pregnancy follow-up may be performed as in the low risk group without any pregnancy complications. If maternal or fetal distress is not observed, delivery is planned between 39+0 -40+6 weeks. Although caesarean section is recommended when estimated fetal weight is 4500 g or more, the mode of delivery may be decided more appropriately on a case-by-case basis. Copyright © 2020 by Türkiye Klinikleri.
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    Effect of molding pressure and firing temperature on the properties of ceramics from natural zeolite
    (Elsevier Ltd, 2023) Erdogmus E.; Sutcu M.; Hossain S.; Bayram M.; Sarı A.; Gencel O.; Ozbakkaloglu T.
    In recent years, there has been growing interest in eco-friendly and sustainable construction materials that reduce environmental impact while maintaining high-performance standards. The brick industry, in particular, is under pressure to develop solutions that incorporate waste and natural-based materials, reducing reliance on traditional energy-intensive manufacturing processes. In response, this study explores the fabrication of ceramic bricks using naturally occurring zeolite, which is widely available and offers promising properties for use in construction. The ceramic matrix is made with natural zeolite and water, pressed at three different pressures, and fired at three different temperatures. The study investigates the impact of varying molding pressures and firing temperatures on the microstructural and mechanical properties of ceramic bricks made with natural zeolite. XRF and XRD techniques were used to analyze the raw material's chemical composition, and TGA tests were conducted to evaluate the bricks' chemical stability. The study finds that the compressive strength of zeolite bricks molded at 15 MPa pressure and fired at 900 ℃ increased from 7.1 MPa to 51.2 MPa when fired at 1100 ℃. Increasing the molding pressure led to a higher compressive strength of the specimens, but the effect was minimal compared to the influence of firing temperature on the compressive strength. The apparent porosity and water absorption of the bricks decreased with increasing molding pressure and firing temperature. Further, clinoptilolite, a zeolite phase, decomposes during firing and transforms into silica polymorphs, feldspathic phases, and glassy phases. As the molding pressure increased, the irregular-shaped pores in the brick specimens decreased. Moreover, the density of the bricks increased with the firing temperature due to sintering between particles in the microstructure. By investigating the impact of molding pressure and firing temperature on the microstructural and mechanical properties of these eco-friendly bricks, this study offers insight into a potential solution for sustainable construction practices. By investigating the impact of pressing pressure and firing temperature on the microstructural and mechanical properties of these eco-friendly bricks, this study demonstrated that optimizing firing temperature and pressing pressure can significantly improve the physical and mechanical properties of zeolite bricks, including bulk density, compressive strength, water absorption, and porosity, while also reducing the environmental impact of the production process. Thus, this study offers insight into a potential solution for sustainable construction practices. © 2023