Browsing by Author "Baytur, Y"
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Item Endometrial fluid in postmenopausal womenInceboz, U; Uyar, Y; Baytur, Y; Kandiloglu, ARItem Evaluation of the Effects of Different Anesthetic Techniques on Neonatal Bilirubin LevelsEskicioglu, F; Ozlem, S; Bilgili, G; Baytur, YObjectives: The aim of the present study was to determine whether different anesthetic techniques applied for vaginal delivery and cesarean section affect neonatal bilirubin levels in the first 24 hours of life. Materials and Methods: A total of 511 neonates delivered by vaginal route or cesarean section were included in the study. The neonates were classified according to method of delivery and anesthetic agents as group A (cesarean section / general anesthesia with sevoflurane), group B (cesarean section / spinal anesthesia with bupivacaine hydrochloride), group C (vaginal delivery with episiotomy / local anesthesia with prilocaine hydrochloride) and group D (vaginal delivery/ no anesthesia). The levels of neonatal serum bilirubin in the groups were compared. Results: There was no difference between group A and group B in terms of neonatal bilirubin levels (p = 0.98). Depending on the use of prilocaine hydrochloride as local anesthetic agent in the vaginal delivery, there was no significant difference between the groups C and D, in terms of the neonatal bilirubin levels (p = 0.99). The serum levels of bilirubin in cesarean section groups were significantly higher than those of the vaginal delivery groups (p < 0.001). Conclusion: Prilocaine hydrochloride used for episiotomy did not exert any effects on neonatal hyperbilirubinemia. However, cesarean section with sevoflurane and bupivacaine hydrochloride seemed to result in increased bilirubin levels.Item Comparison of the Bishop score, body mass index and transvaginal cervical length in predicting the success of labor inductionUyar, Y; Erbay, G; Demir, BC; Baytur, YTo evaluate the role of ultrasonographic and various maternal and fetal parameters in predicting successful labor induction. Body mass index, cervical length, dilatation, effacement, Bishop score, parity, maternal age and birth weight were evaluated in 189 singleton pregnant women at 37-42 weeks of gestation and having induction of labor. All underwent induction of labor with oxytocin. Body mass index was calculated using the formula weight (kg)/height(2) (m), cervical measurement was performed by transvaginal ultrasonography and Bishop score was determined by digital examination of cervix. Logistic regression analysis indicated that the cervical length and body mass index were independent variables in determining the risk of cesarean section (OR = 1.206, P = 0.000, CI 95% = 1.117-1.303; OR = 1.223, P = 0.007, CI 95% = 1.058-1.414 respectively). In multiple linear regression analysis, the effect of cervical length and body mass index on induction delivery interval was found to be statistically significant (t = 5.738, P = 0.000; t = 2.680, P = 0.009, respectively). ROC curve showed that the best parameter in predicting the risk of cesarean section was cervical length and that cervical length and body mass index were better parameters compared to the Bishop score (the areas under the curve are 0.819, 0.701 and 0.416, respectively). Body mass index and transvaginal cervical length were better predictors compared to the Bishop score in determining the success of labor induction.Item Bladder carcinoma in pregnancy: unusual cause for frequent urinary tract infection-case reportMuezzinoglu, T; Inceboz, U; Baytur, Y; Nese, NItem Vein of Galen aneurysm that was diagnosed prenatally and supracardiac obstructed total anomalous pulmonary venous return with pulmonary hypertension: case reportTanriverdi, S; Baytur, Y; Tansug, N; Çetin, M; Coskun, SThe vein of Galen aneurysm is the most common form of symptomatic cerebrovascular malformation in neonates and infants. This anomaly may be diagnosed prenatally by several imaging modalities and causes high cardiac output, which may lead to cardiac failure, in newborns. Total anomalous pulmonary venous return is a rare entity that makes up approximately 0.4%-2% of all congenital heart diseases. The most common type of total anomalous pulmonary venous return is the supracardiac type. The pulmonary veins drain to a confluence posterior to the heart and then to a vertical vein, most commonly on the left, which enters the innominate vein and the drains to the right atrium. Obstructed pulmonary veins with supracardiac- type total anomalous pulmonary venous return can cause severe cardiac and respiratory failure. In this article, a case of a neonate with a vein of Galen aneurysm diagnosed prenatally by magnetic resonance imaging, and a supracardiac obstructed type of total anomalous pulmonary venous return with pulmonary hypertension is presented.Item Acute abdomen and massive hemorrhage due to placenta percreta leading to spontaneous uterine rupture in the second trimesterUlkumen, BA; Pala, HG; Baytur, YPlacental invasion anomalies are rare obstetrical complications. They cause severe third trimester hemorrhage, severe postpartum bleeding, and maternal morbidity and mortality unless they are diagnosed antenatally. We present a rare case with placenta percreta leading to spontaneous uterine rupture during the second trimester with an acute abdomen and hypovolemia.Item Comparative effects of risedronate, atorvastatin, estrogen and SERMs on bone mass and strength in ovariectomized ratsUyar, Y; Baytur, Y; Inceboz, U; Demir, BC; Gumuser, G; Ozbilgin, KObjective: The aim of this study was to investigate bone protective effects of risedronate, atorvastatin, raloxifene and clomiphene citrate in ovariectomized rats. Methods: Our study was conducted on 63 rats at Experimental Research Center of Celal Bayar University. Six-month-old rats were divided into seven groups. There were five drug administered ovariectomized groups, one ovariectomized control group without drug administration and one non-ovariectomized control group without drug administration. Eight weeks postovariectomy, rats were treated with the bisphosphonate risedronate sodium, the statin atorvastatin, the estrogen 17 beta-estradiol and the selective estrogen receptor modulators (SERMs) raloxifene hydrochloride and clomiphene citrate by gavage daily for 8 weeks. At the end of the Study, rats were killed under anesthesia. For densitometric evaluation, left femurs and tibiae were removed. Left femurs were also used to measure bone volume. Right femurs were used for three-point bending test. Results: Compared to ovariectomized group, femur cortex volume increased significantly in nonovariectomized group (p=0.016). Compared to non-ovariectomized group, distal femoral metaphyseal and femur midshaft bone mineral density values were significantly lower in ovariectomized group (p = 0.047). In ovariectomy + atorvastatin group, whole femur and femur midshaft bone mineral density and three-point bending test maximal load values were significantly higher than ovariectomized group (p = 0.049, 0.05, and 0.018). When compared to the ovariectomized group, no significant difference was found with respect to femoral maximum load values in groups treated with risedronate, estrogen, raloxifene and clomiphene (p = 0.602, 0.602, 0.75, and 0.927). In ovariectomy + risedronate group, femur midshaft bone mineral density values were significantly higher than the values in ovariectomized group (p = 0.023). When compared to ovariectomized group, no significant difference was found with respect to femur midshaft bone mineral density values in groups treated with estrogen, raloxifene and clomiphene (p = 0.306, 0.808, and 0.095). Conclusions: While risedronate sodium prevented the decrease in bone mineral density in ovariectomized rats, atorvastatin maintained mechanical characteristics of bone and also prevented the decrease in bone mineral density as risedronate sodium. (C) 2009 Elsevier Ireland Ltd. All rights reserved.Item Prenatal Diagnosis of Placenta Percreta with UltrasoundUlkumen, BA; Pala, HG; Baytur, YThe incidence of the placental invasion anomalies are increasing, mainly due to repeat cesarean deliveries. Placenta percreta occurs if these villi perforate the serosa and also sometimes into adjacent organs such as the bladder. The prenatal diagnosis is very important because of the high maternal morbidity and mortality rates without the appropriate surgical planning. The adherent placentas will result in severe early postpartum bleeding, just after the delivery of the fetus. Severe hemorrhage usually results rapidly in disseminated intravascular coagulation (DIC), shock, multiorgan failure or death. The surgery is also challenging due to the risk of the adjacent tissue damage, such as bladder or ureteral injury. Approximately 1 in every 3 cases need intensive care. We present here a prenatally diagnosed, 31-year-old gravida 7 para 2 abortus 4 pregnant case with placenta percreta and rewiev the relevant literature about the key aspects in the ultrasonograhic diagnosis and underlie the key points in the diagnosis.Item Antenatally Diagnosed Epigastric Heteropagus Twin: Case ReportGünsar, C; Sencan, A; Baytur, Y; Asci, A; Mir, EConjoined twinning is a rare anomaly with a rate of 1 per 50 000-100 000 live births. Heteropagus twinning (parasitic twinning) is a specific and much rarer form of conjoined twinning. In this anomaly, while one of the twins (host twin) develops completely, the other one develops asymmetrically attached to and dependent upon the host (parasitic twin). Number of conjoined twins antenatally diagnosed as heteropagus is considerably few in the literature. Accurate antenatal diagnosis can be helpful to inform the family in the decision to terminate or continue with pregnancy. Antenatal three-dimensional sonography provides an accurate diagnosis and recognition of the details of the anomaly better. In this paper, a case that was diagnosed with epigastric heteropagus twinning with three-dimensional ultrasonography at 17 weeks of gestation with a successful separation with surgery is presented.Item Effect of Anaesthesia Methods for Regaining Daily Life Activities in Cesarean PatientsGürsoy, C; Ok, G; Aydin, D; Eser, E; Erbüyün, K; Tekin, I; Baytur, Y; Uyar, YObjective: Postpartum period is physically, socially and emotionally a difficult time for the parents and the baby to become a family. We tried to investigate how the anaesthesia method affects patients who underwent cesarean delivery, as a factor which also affects this period. Methods: Two hundred and six parturients, who underwent elective cesarean delivery in Celal Bayar University Hafsa Sultan Hospital were recruited for our study. After demographic data and anaesthesia methods were noted, an EQ-5D health survey and Katz ADL scale were evaluated face to face 24 hours postoperatively, and by telephone on the 5th postoperative day. Results: The percentage of patients who had general anaesthesia was 35.2% (n=71), while 19.8% (n=40) had epidural anaesthesia and 45% (n=91) had spinal anaesthesia. Among -these three methods, the EQ-5D health survey revealed that the outcome at postoperative 24 hours was best in epidural anaesthesia and that general anaesthesia outcome was the worst (p=0.007). The Katz ADL scale at postoperative 24. hours showed that epidural anaesthesia was better than the other methods for regaining daily life activities (p< 0.05). Conclusion: Our study showed that epidural anaesthesia had the most effective role among the methods in regaining daily life activities after elective cesarean delivery, which was demonstrated using the EQ-5D health survey and Katz ADL scale.Item Retrospective analysis of fetal anterior abdominal wall defectsUlkumen, BA; Pala, HG; Baytur, Y; Koyuncu, FMObjective: To analyze fetal abdominal defects diagnosed during the prenatal period in the perinatology department in a tertiary center in Turkey. Methods: This retrospective study consisted of 27 cases diagnosed with fetal abdominal wall defects between January 2011 and February 2014 in the perinatology outpatient clinic of Celal Bayar University, Manisa, Turkey. Results: Eighteen (66.7%) cases were diagnosed with omphalocele, 6 (22.2%) had gastroschisis, and 3 (11.1%) had limb body wall defects. Twenty-one (77.7%) patients diagnosed either as omphalocele or limb body wall defect were offered karyotype analysis; 11 (52.4%) of them accepted the intervention, and 2 of the 11 patients (18.2%) had abnormal karyotype. Regarding the omphalocele cases; 12 (66.6%) cases had isolated omphalocele, whereas 6 of the 18 cases (33.3%) had associated anomalies. Expectant management was performed in 8 (66.7%) of 12 isolated omphalocele cases. Two of the isolated omphalocele group (16.7%) had missed abortion, the other 2 (16.7%) had termination of the pregnancy because of the associated chromosomal anomaly (47, XXY and 45, X0). Three of the gastroschisis group (50%) had missed abortion, and the other 3 (50%) had expectant management with cesarean delivery between 38-39 gestational weeks. Cases with limb body wall defect were terminated due to the lethal condition. Conclusion: The prenatal diagnosis of fetal abdominal wall defects is important, because they differ greatly in terms of perinatal and neonatal morbidity and mortality due to underlying chromosomal abnormalities and associated structural anomalies.