Browsing by Author "Berberoglu, M"

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    PREDICTION OF IMPACT RESULTS ON CEMENT BASED MORTAR SLABS
    Erdem, RT; Berberoglu, M
    Grout mortars are non-permeable, non-shrink and flowing cement based construction materials. Due to reaching high strength values in a short time, grout mortars are used in construction works. However, behavior of cement mortars under sudden impact loading is complex. Because, loading duration is very short in impact scenarios, effect of strain rates is much higher than static loading. So, dynamic responses and failure modes of the materials are different. In this study, it is aimed to investigate the dynamic behavior of slabs that are produced by cement based grout mortars under impact loading. A drop test setup is developed for this purpose and several measurement devices utilized in the impact experiments. Acceleration, displacement and impact load values are obtained as well as drop durations and drop numbers. After completing the experimental part of the study, artificial neural networks (ANN) analysis which is used to model different physical dynamic processes depending on the experimental variables is performed to predict the impact results. So, ANN analysis is used in the verification of experimental study. Due to the comparison of experimental and analysis results, it is considered that proposed ANN model can be used for the evaluation of the dynamic responses of test specimens.
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    Current Practice in Diagnosis and Treatment of Growth Hormone Deficiency in Childhood: A Survey from Turkey
    Poyrazoglu, S; Akçay, T; Arslanoglu, I; Atabek, ME; Atay, Z; Berberoglu, M; Bereket, A; Bideci, A; Bircan, I; Böber, E; Can, S; Cesur, Y; Darcan, S; Demir, K; Dündar, B; Ersoy, B; Esen, I; Güven, A; Kara, C; Keskin, M; Kurtoglu, S; Memioglu, N; Özbek, MN; Özgen, T; Sari, E; Siklar, Z; Simsek, E; Turan, S; Yesilkaya, E; Yüksel, B; Darendeliler, F
    Objective: Approaches to diagnosis and treatment of growth hormone deficiency (GHD) in children vary among countries and even among centers in the same country. This survey, aiming to facilitate the process of preparing the new consensus on GHD by the Turkish Pediatric Endocrinology and Diabetes Society, was designed to evaluate the current practices in diagnosis and treatment of GHD in different centers in Turkey. Methods: A questionnaire covering relevant items for diagnosis and treatment of GHD was sent out to all pediatric endocrinology centers. Results: Twenty-four centers returned the questionnaire. The most frequently used GH stimulation test was L-dopa, followed by clonidine. Eighteen centers used a GH cut-off value of 10 ng/mL for the diagnosis of GHD; this value was 7 ng/mL in 4 centers and 5 ng/mL in 2 centers. The most frequently used assay was immunochemiluminescence for determination of GH, insulin-like growth factor-1 and insulin-like growth factor binding protein-3 concentrations. Sex steroid priming in both sexes was used by 19 centers. The most frequently used starting dose of recombinant human GH (rhGH) in prepubertal children was 0.025-0.030 mg/kg/day and 0.030-0.035 mg/kg/day in pubertal children. Growth velocity was used in the evaluation for growth response to rhGH therapy in all centers. Anthropometric measurements of patients every 3-6 months, fasting blood glucose, bone age and thyroid panel evaluation were used by all centers at follow-up. Main indications for cessation of therapy were decreased height velocity and advanced bone age. Fourteen centers used combined treatment (rhGH and gonadotropin-releasing analogues) to increase final height. Conclusion: Although conformity was found among centers in Turkey in current practice, it is very important to update guideline statements and to modify, if needed, the approach to GHD over time in accordance with new evidence-based clinical studies.