Browsing by Author "Bilaç C."
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Item Acute irritant contact dermatitis due to 'apium graveolens'(2007) Ermertcan A.T.; Öztürkcan S.; Şahin M.T.; Bilaç C.; Bilaç D.B.[No abstract available]Item Behçet's disease associated with hidradenitis suppurativa [27](2007) Sahin M.T.; Öztürkcan S.; Türel-Ermertcan A.; Yurtman-Havlucu D.; Bilaç C.[No abstract available]Item Plastic detection comb better than visual screening for diagnosis of head louse infestation(2008) Balcioglu C.; Burgess I.F.; Limoncu M.E.; Şahin M.T.; Ozbel Y.; Bilaç C.; Kurt O.; Larsen K.S.Finding lice can be difficult in head louse infestation. We compared a new louse detection comb with visual inspection. All children in two rural Turkish schools were screened by the two methods. Those with lice were offered treatment and the results monitored by detection combing. Children with nits only were re-screened to identify latent infestations. Using visual inspection we found 214/461 children (46%) with nits but only 30 (6·5%) with live lice. In contrast detection combing found 96 (21%) with live lice, of whom 20 had no nits. Detection combing was 3·84 times more effective than visual inspection for finding live lice. Only 10/138 (7·2%) children with nits and no lice were found to have active infestation by day 16. We found that the detection comb is significantly (P < 0·001) more effective than visual screening for diagnosis; that nits are not a good indicator of active infestation; and that treatment with 1% permethrin was 89̇6% effective. © 2008 Copyright © 2008 Cambridge University Press.Item Psoriatic plaque erosion: A rare side effect of methotrexate(2009) Bilaç C.; Türel Ermertcan A.; Öztürkcan S.; Şahin M.; Öztürk F.; Bayraktar Bilaç D.; Işisaǧ A.[No abstract available]Item Comparison of two combs in the detection of head lice in school children.(2009) Kurt O.; Tabak T.; Kavur H.; Muslu H.; Limoncu E.; Bilaç C.; Balcioǧlu I.C.; Kaya Y.; Ozbel Y.; Larsen K.The diagnostic efficacies of two metal pin lice combs having different spacing between their teeth were compared in two cohorts of school children, aged between 7 and 15 years, from different villages of Manisa, Turkey. Head lice infestation was evaluated with comb A (0.18 mm of distance between the teeth) in 95 children in Cavusoglu village, and with comb B (0.15 mm of distance between the teeth) in 146 children in Yesilköy village, compared to visual inspection. Five of 95 (5.3%) children in Cavusoglu village and 5 of 146 (3.4%) children in Yesilköy village were found to harbor live head lice with combing, while none was detected during the visual inspection. The difference between the infestation rates of two cohorts was statistically insignificant (p > 0.05). With visual screening, 15 and 16 children with louse eggs were identified in Cavusoglu and Yesilköy villages, respectively. With combing in these villages, 5 and 8 children, respectively, with louse eggs were identified and 3 and 5 children, respectively, were detected only with combing, not with visual screening. In conclusion, combing is more effective than visual inspection in head lice detection, but there were no significant difference between the two combs either in lice detection or in usage.Item Case report of a late onset bowenoid papulosis progressing to squamous cell carcinoma: Letter to the editor(Turkiye Klinikleri, 2009) Aydin N.; Türel Ermertcan A.; Öztürkcan S.; Bilaç C.; Yoleri L.; Temiz P.[No abstract available]Item Sorafenib-induced erythema multiforme in metastatic renal cell carcinoma(2009) Bilaç C.; Müezzinoǧlu T.; Ermertcan A.T.; Kayhan T.C.; Temeltaş G.; Özütrkcan S.; Temiz P.Sorafenib is a new therapeutic agent being used in metastatic renal cell carcinoma, hepatocellular carcinoma, and malignant melanoma. The most frequently seen cutaneous side effects due to sorafenib are erythema, exfoliative dermatitis, acne vulgaris, and flushing. Folliculitis, eczema, and erythema multiforme are other, rare side effects of sorafenib. A 59-year-old man underwent left radical nephrectomy due to renal cell carcinoma 8 months ago, and after the operation he received immunochemotherapy and then sorafenib. On the third day of sorafenib therapy his lesions occurred. His dermatologic examination revealed multiple erythematous papules on his neck, arms, and legs and bullae and iris lesions on his palms and soles. He was diagnosed as having erythema multiforme. In the literature we found only 1 other erythema multiforme case due to sorafenib. We present this interesting case to show and discuss cutaneous side effects of sorafenib, especially erythema multiforme as a very rare cutaneous side effect. © 2009 Informa UK Ltd.Item A case report of postpubertal eruptive syringoma triggered with antiepileptic drugs(2010) Öztürk F.; Ermertcan A.T.; Bilaç C.; Temiz P.Eruptive syringoma is a rare variant of syringoma, which typically occurs in large numbers as multiple yellow-brown colored papules. It usually presents before or during puberty. The pathogenesis of eruptive syringoma is unclear. It could represent a hyperplastic response of the eccrine ducts to an inflammatory reaction caused by an unknown trigger. The association between drugs and eruptive syringoma has not been reported in the literature until now. A 34-year-old woman with multiple asymptomatic papular eruptions of nine years' duration visited the authors' outpatient clinic. She had been using antiepileptic drugs for epilepsy for 10 years. Dermatological examination revealed multiple skin-colored to brownish papules, 1-3 mm in diameter, on the trunk and neck. Skin biopsy was performed from a lesion on the neck. According to clinical and histopathological findings, the patient was diagnosed as having eruptive syringoma. This case is very interesting, because the patient had been using antiepileptic drugs for a long time and the onset of her lesions was in postpubertal period. The authors' hypothesize that her lesions occured due to antiepileptics which may be a trigger of syringomatous proliferation. The authors conclude that drugs, especially antiepileptics, should be kept in mind in reference to the etiology of eruptive syringomas. Copyright © 2010 Journal of Drugs in Dermatology.Item Nonsyndromic multiple basal cell carcinomas successfully treated with imiquimod 5% cream(2010) Kocaba E.; Ermertcan A.T.; Bilaç C.; Bilaç D.B.; Temiz P.This report describes the case of a 60-year-old man with nonsyndromic multiple basal cell carcinomas that responded to imiquimod 5% cream. The patient had no additional anomalies suggesting any syndromes associated with multiple basal cell carcinomas. By applying the agent 5 times a week for 20 weeks, we obtained good clinical results, and we confirmed the improvement with histopathologic examination. We suggest that patients with multiple basal cell carcinomas should be interviewed about and tested for the associated syndromes, and topical imiquimod should be kept in mind as an alternative therapy choice in these patients. © 2010 Informa Healthcare USA, Inc.Item Acute generalized exanthematous pustulosis with lymphangitis triggered by a spider bite(2010) Ermertcan A.T.; Demirer O.; Inanir I.; Bilaç C.; Temiz P.Acute generalized exanthematous pustulosis (AGEP) is a rare, severe cutaneous reaction pattern that, in the majority (>90%) of cases, is related to administration of medication. It can be seen in both genders and in all ages. The cutaneous manifestations of AGEP are usually seen 1-14 days after drug administration. A 39-year-old woman presented to our outpatient clinic with the complaint of generalized erythema, burning, and rash. She explained that 2 days before presentation a spider bite had occurred on her left forearm, after which she had experienced pain and erythema spreading gradually to the left upper extremity. On her dermatologic examination, she had an indurated necrotic plaque on the left forearm, which had an upward-spreading linear erythema. Additionally, she had diffuse erythema on her body and small pustules over erythematous skin, especially located on the left popliteal fossa and gluteal region. Based on the clinical and histopathologic findings, she was diagnosed as having AGEP. Because there was no drug use in her history, we attributed her AGEP lesions to the spider bite. This case is interesting, because the patient also had lymphangitis. Herein, we present the fifth case reported in the literature of AGEP caused by a spider bite. © 2010 Informa UK Ltd.Item Are regular controls conducted in schools adequate in lowering the incidence of head lice (Pediculus capitis) infestation?; [Okullarda düzenli aralıklarla gerçekleştirilen kontroller saç biti (Pediculus capitis) insidansını düşürmekte yeterli olabilir mi?](Veteriner Fakultesi Dergisi, 2012) Balcioğlu İ.C.; Kurt Ö.; Limoncu M.E.; Ermiş V.Ö.; Tabak T.; Oyur T.; Muslu H.; Kavur H.; Görgün S.; Girginkardeşler N.; Yereli K.; Bilaç C.; Özbel Y.In the present study, school children of similar age-groups from two villages of Manisa province, namely Osmancalı and Maldan, were examined in regular time periods to monitorize the changes in the incidence of head lice (Pediculus capitis). A total of 2091 children (1565 in Osmancalı and 526 in Maldan) were combed with a newly-designed lice comb (PDC®, KSL Consulting, Helsinge, Denmark) four times in May and November in 2008 and 2009. The assessment of the results was conducted with SPSS® v.15 program using CHAID and logistic regression analysis. The results of the periodic examinations of the children showed that the infestation rate of girls were found to be higher significantly compared to boys (P<0.001), and the incidence of head lice infestation in boys from Osmancalı was found three times higher than the incidence in boys in Maldan (P=0.002). In addition, regular dry combing and treatment lowered the infestation rates among girls significantly (P=0.001). According to the results of the study, regular dry combing of school children with specially-designed lice combs may be essential for the control of this common infestation, especially in rural areas. © 2012, Veteriner Fakultesi Dergisi. All rights reserved.Item Chronic actinic damage of facial skin(Elsevier Inc., 2014) Bilaç C.; Şahin M.T.; Öztürkcan S.Chronic actinic damage of the skin manifests itself as extrinsic skin aging (photoaging) and photocarcinogenesis. During the last decade, substantial progress has been made in understanding cellular and molecular mechanisms of photoaging. DNA photodamage and ultraviolet-generated reactive oxygen species are the initial events that lead to most of the typical histologic and clinical manifestations of chronic photodamage of the skin. Chronic actinic damage affects all layers of the skin. Keratinocytes, melanocytes, fibroblasts, and endothelial cells are altered by ultraviolet radiation and can result in numerous changes in human skin, particularly the skin of fair-skinned individuals. These changes include actinic keratosis, thickening and wrinkling, elastosis, telengiectasia, solar comedones, diffuse or mottled hyperpigmentation, and skin cancers. There are many options in the treatment of changes caused by chronic actinic damage. The most effective measure of prevention of the photoaging and photocarcinogenesis is sun protection. © 2014 Elsevier Inc.Item Quality of life in children with dermatological diseases; [Çocuklarda dermatolojik hastaliklarda yaşam kalitesi](Istanbul Assoc. of Dermatology and Venerology, 2014) Bilaç C.; Bilaç Ö.; Öztürkcan S.Quality of life is a multidimensional measure that, besides personal health status, reflects personal well-being as well. A number of quality of life scales for children and adolescents have been developed. The measurement of quality of life in children is different from measuring quality of life of adults. Knowledge of the this difference related to child development stages is important for researchers who improve and use the quality of life scales. Most studied have been performed on the quality of life in children with dermatological diseases, such as atopic dermatitis and psoriasis, as well as alopecia areata, dermatomyositis, ectodermal dysplasia, photosensitivity disorders, molluscum contagiosum, neurofibromatosis, and vitiligo. In this paper, we reviewed the literature on the quality of life in children with dermatologic diseases.Item Disease severity scoring systems in dermatology; [Dermatolojide hastalik şiddeti skorlama sistemleri](Istanbul Assoc. of Dermatology and Venerology, 2016) Bilaç C.; Şahin M.T.; Öztürkcan S.Scoring systems have been developed to interpret the disease severity objectively by evaluating the parameters of the disease. Body surface area, visual analogue scale, and physician global assessment are the most frequently used scoring systems for evaluating the clinical severity of the dermatological diseases. Apart from these scoring systems, many specific scoring systems for many dermatological diseases, including acne (acne vulgaris, acne scars), alopecia (androgenetic alopecia, tractional alopecia), bullous diseases (autoimmune bullous diseases, toxic epidermal necrolysis), dermatitis (atopic dermatitis, contact dermatitis, dyshidrotic eczema), hidradenitis suppurativa, hirsutismus, connective tissue diseases (dermatomyositis, skin involvement of systemic lupus erythematosus (LE), discoid LE, scleroderma), lichen planoplaris, mastocytosis, melanocytic lesions, melasma, onychomycosis, oral lichen planus, pityriasis rosea, psoriasis (psoriasis vulgaris, psoriatic arthritis, nail psoriasis), sarcoidosis, urticaria, and vitiligo, have also been developed. Disease severity scoring methods are ever more extensively used in the field of dermatology for clinical practice to form an opinion about the prognosis by determining the disease severity; to decide on the most suitable treatment modality for the patient; to evaluate the efficacy of the applied medication; and to compare the efficiency of different treatment methods in clinical studies.Item Hair loss due to methylphenidate use: A case study(Medknow Publications, 2018) Bilac O.; Kütük M.; Bilaç C.[No abstract available]Item The relationship of treatment modality in alopecia areata with life quality, anxiety, and depression; [Alopesi areatada tedavi yöntemi ile yaşam kalitesi, anksiyete ve depresyon ilişkisi](Turkiye Klinikleri, 2018) Bilaç C.; Kutlubay Z.; Öztürkcan S.; Şahin M.T.; Kocabaş E.; Dinç G.; Serdaroğlu S.Objective: Alopecia areata is a recurrent nonscarring type of hair loss that can affect any hair-bearing area. This study aims to evaluate the anxiety and depression risks of patients diagnosed with alopecia areata, by using Dermatology Quality of Life Index (DLQI), Short Form-36 (SF-36), and Hospital Anxiety Depression scales. Material and Methods: Patients with a diagnosis of alopecia areata, alopecia totalis and alopecia universalis who were admitted to Celal Bayar University Medical Faculty and Cerrahpasa University Medical Faculty, Dermatology outpatient clinics, were included in the study. Patients with a co-existing dermatological or psychiatric disease were excluded. 72 patients between the ages of 18 and 60 years were included in the study. Results: DLQI scores of the patients at the beginning and at the end of six-month therapy were compared and an overall statistically insignificant decrease was observed, particularly in the systemic treatment groups. At the end of six months, average SF-36 scores increased, pointing an improvement in quality of life. At the end of six months anxiety scores also decreased, especially for the patients receiving systemic treatment (p=0,055). Conclusion: The treatment choices and effectivities for diseases such as alopecia areata is limited. Thus therapy success should not only be based on the clinical outcome, but also on the changes of quality of life indexes and depression/anxiety scores, which are also important on the prognosis of the disease. © 2018 by Türkiye Klinikleri.Item Evaluation of the effect of surgical treatment on quality of life with the Dermatology Life Quality Index in patients with facial nonmelanoma skin cancer(Blackwell Publishing Inc., 2020) Çetinarslan T.; Evrenos M.K.; Bilaç C.; Özyurt B.; Türel Ermertcan A.Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur as a result of treatments or due to primary disease. Therefore, the quality of life of patients could be affected. To determine the effect of surgical treatment on quality of life of the patients with facial NMSC using the Dermatology Life Quality Index (DLQI) at baseline and 3 months after surgery. We aimed to see if there was any improvement in quality of life scores after surgery, and to identify factors affecting quality of life. A total of 255 patients; 174 basal cell carcinoma (BCC) (68.2%) and 81 squamous cell carcinoma (SCC) (31.8%) were included in our study. All participants completed DLQI at baseline and 3 months after surgery. The mean total DLQI scores were 6.37 ± 6.28 in patients with BCC, and 6.35 ± 6.16 in patients with SCC. The mean total DLQI scores were 3.96 ± 5.14 in patients with BCC (P <.001), and 4.49 ± 5.24 in patients with SCC (P <.001) 3 months after surgery. In patients with primary skin cancer, all subscale scores and total DLQI scores were worse than the recurrent skin cancer group in both BCC and SCC at baseline. According to the treatment modalities, total DLQI scores and all subscales were worse in the graft group in BCC and SCC patients at baseline. Interestingly, the sex and the type of skin cancer did not affect quality of life, but tumor localization ([auricula OR: 6.45 [95% CI: 1.28-37.47] and eyelid OR:0.20 [95% CI: 0.04-0.96]) treatment procedure ([flap procedure OR: 7.90 [95% CI: 2.64-23.62] and graft procedure OR: 5.47 [95% CI: 1.60-18.71]) and, primary tumor OR:3.86 (95% CI: 1.01-14.78) were significant. The quality of life of skin cancer patients was affected by tumor localization, treatment procedure, primary, or recurrent tumor. The quality of life showed a significant improvement in patients with facial NMSC after surgical treatment. However, the type of NMSC seems to have no effect on the quality of life. © 2020 Wiley Periodicals LLC.Item Functional medicine with dermatology insite: A systematic approach for diagnosis and treatment of chronic diseases(Blackwell Publishing Inc., 2020) Gökyayla E.; Türel Ermertcan A.; Bilaç C.[No abstract available]Item Quality of life, anxiety and depression in patients with androgenetic alopecia(Medcom Limited, 2021) Bilaç C.; Öztürkcan S.; Sahin M.T.; Kutlubay Z.; Serdaroglu S.; Yasar A.; Dinç G.Background: Androgenetic alopecia (AGA) is a common form of hair loss, which can result in body image disorder and negative social feelings. Aim: The aim of this study was to evaluate the quality of life (QoL) and the risk of anxiety and depression in AGA patients. Method: Sociodemographic data of the patients and clinical severity of the disease were recorded. The QoL score of patient and controls was evaluated with DLQI and SF-36 instruments, their anxiety and depression risks were evaluated with HAD (HAD-A and HAD-D) instruments. Results: Sixty-eight patients with AGA were included in our study. Young male AGA patients' quality of life levels were found to be low according to role limitations due to emotional problems, emotional well-being and emotional scores of SF-36 scale and younger female AGA patients quality of life levels were also found to be low according to role limitations due to emotional problems, and emotional scores of SF-36 scale. The DLQI scores of patients of both sex were found to be sig nificantly higher compared to control group. According to anxiety and depression risk assessment with HAD scale, it was found that 28.6% and 73.5% of patients were prone to suffer from anxiety and depression respectively. Conclusion: Apart from managing alopecia, practitioners should be aware of the possible psychosocial distress of AGA patients and manage accordingly. © 2021 Medcom Limited. All rights reserved.Item The eating attitudes, sleep and personality characteristics, and effects of on acne severity in adolescents with acne vulgaris(2021) Bilaç Ö.; Bilaç C.; Tahıllıoğlu A.; Uzun A.D.; Dilcan M.; Önder A.; Kavurma C.; Uzunoğlu G.Background: Acne vulgaris (AV) is a very common dermatological problem during adolescence. It is reported that it has a multifactorial etiology and nutritional attitudes, insufficient and poor-quality sleep may cause increased severity of AV. Aim: We aimed to investigate the sleep, eating attitudes and personality traits, and their effects on acne severity in adolescents with acne. Methods: The study sample was formed of 37 adolescent girls aged 12–18 years who presented at the University Dermatology Clinic and were diagnosed with AV and 37 adolescents without AV-matched age and gender. Eating attitude test, Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) Personality Inventory Child Form, and child and parent forms of DSM-5 Level 2 Sleep Disorders were applied to in both groups. The AV severity assessed by using the Global Acne Grading Scale (GAGS). Psychiatric diagnosis was excluded with clinical interview according to the Schedule for Affective Disorders and Schizophrenia for school-aged children: Present and Lifetime Version (K-SADS-PL-DSM-5-T). Results: The mean age of adolescents with and without AV was 15.3 (standard deviation [SD] = 1.7), 15.4 (SD = 1.8), respectively. The mean disease duration of adolescents with AV was 20.4 (SD = 15.2) months, and the mean GAGS score was 23.24 (SD = 9.4). It was determined that eating attitudes, sleep, and personality characteristics of adolescents were similar in both groups. Eating attitudes, sleep, and personality characteristics had no direct effect on acne severity. Conclusion: Although this study demonstrates that eating attitudes, sleep, and personality characteristics were similar in adolescents with and without AV and these variables had no effect on acne severity, these results may have been obtained because of the severity scores of adolescents with AV were “moderate.” There is a need for researches examining these variables in adolescents with “severe” AV. © 2021 Turkish Journal of Dermatology.