Browsing by Author "Bilgiç A."

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    Comparison of Changes in SRS-22 Values with Improvement in Cobb Angles after Posterior Fusion Surgery in Adolescent Idiopathic Scoliosis; [Vergleich der Veränderungen der SRS-22-Werte mit der Verbesserung der Cobb-Winkel nach einer dorsalen Fusionsoperation bei adoleszenter idiopathischer Skoliose]
    (Georg Thieme Verlag, 2022) Gem K.; Hancioglu S.; Bilgiç A.; Erkan S.
    Introduction The purpose of this study was to evaluate the relationship between the correction rate in Cobb angle and the improvement in quality of life profile in terms of Scoliosis Research Society (SRS)-22 values. Patients and Methods Between January 2007 and December 2013, posterior instrumentation and fusion was performed to 30 patients with adolescent idiopathic scoliosis (AIS). Patients were grouped according to their improvement rate in Cobb angles after surgery. Patients with an improvement rate of > 80% were grouped as Group A; those with an improvement rate of > 60% and ≤ 80% as Group B and those with an improvement rate of ≤ 60% were grouped as Group C. The SRS-22 questionnaire of these three groups was calculated and their relationship with the improvement in Cobb angle was evaluated. Results No statistical difference was found among the three groups in terms of pain, appearance, function, spirit, satisfaction, and SRS-22 values (all p > 0.05). Conclusion The results of this study demonstrate that the degree of correction rate does not correlate with the degree of improvement in the SRS-22 questionnaire in patients with AIS that underwent posterior fusion and instrumentation. © 2022 Georg Thieme Verlag. All rights reserved.
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    Cutaneous findings in patients with acromegaly and its relationship with concomitant endocrinopathies
    (John Wiley and Sons Inc, 2024) An İ.; Kahraman F.C.; Bilgiç A.; Aktürk A.Ş.; Albayrak H.; Kartal D.; Çınar S.L.; Solak S.S.; Uslu M.; Şanlı H.E.; Yıldızhan İ.K.; Şahin M.T.; Zindanci İ.; Savaş S.; Ayhan E.; Cinel M.; Ataş E.N.S.; Aydemir M.; Selek A.; Elbüken G.; Zuhur S.S.; Karaca Z.; Bülbül B.Y.; Ünübol M.; Demir Ö.; Hekimsoy Z.; Tuna M.; Asilsoy M.; Çetin S.
    Objectives: Skin changes in acromegaly are often the first sign of the disease. The aim of this study was to describe the cutaneous findings in patients with acromegaly. In addition, a secondary aim was to investigate the possible association of these findings with remission status and concomitant endocrinopathies. Design, Patients, and Measurements: In this prospective multicenter study, 278 patients over the age of 18 years with acromegaly who were followed up in 14 different tertiary healthcare institutions were included. These patients, who were followed up by the Endocrinology Department, were then referred to a dermatologist for dermatological examination. The frequency of skin lesions was investigated by detailed dermatologic examination. Dermatological diagnosis is reached by clinical, dermatological and/or dermoscopic examination, and rarely skin punch biopsy examinations in suspicious cases. The possible association of the skin findings between remitted and nonremitted patients and with concomitant endocrinopathies were evaluated. Results: The most common skin findings in patients with acromegaly in our study were skin tags (52.5%), cherry angiomas (47.4%), seborrhoea (37%), varicose veins (33%), acneiform lesions (28.8%), hyperhidrosis (26.9%) and hypertrichosis (18.3%). Hypertrichosis was significantly more prevalent in patients nonremitted (p:.001), while xerosis cutis was significantly more prevalent in patients remitted (p:.001). The frequency of diabetes mellitus and hypothyroidism was significantly higher in patients with varicose veins and seborrhoeic keratosis than those without. Additionally, the coexistence of hypothyroidism, hyperthyroidism and galactorrhea was significantly higher in patients with Cherry angioma than in those without Cherry angioma (p-values:.024,.034 and.027, respectively). The frequency of hypogonadism in those with xerosis cutis was significantly higher than in those without (p:.035). Conclusions: Cutaneous androgenization findings such as skin tag, seborrhoea, acne and acanthosis nigricans are common in patients with acromegaly. Clinicians should be aware that skin findings associated with insulin resistance may develop in these patients. It can be said that the remission state in acromegaly has no curative effect on cutaneous findings. Only patients in remission were less likely to have hypertrichosis. This may allow earlier review of the follow-up and treatment of acromegaly patients presenting with complaints of hypertrichosis. Additionally, it can be said that patients with skin findings such as cherry angioma may be predisposed to a second endocrinopathy, especially hypothyroidism. Including dermatology in a multidisciplinary perspective in acromegaly patient management would be beneficial to detect cutaneous findings earlier. © 2024 John Wiley & Sons Ltd.