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  1. Home
  2. Browse by Author

Browsing by Author "Bilgin, E"

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    High efficiency in labeling of RBC with Tc-99m in in vitro conditions
    Ertay, T; Bekis, R; Tasci, C; Bilgin, E; Durak, H
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    Determination of bone marrow radiation dose using MIRDOSE3 package program in thyroid cancer patients
    Parlak, Y; Demir, M; Erees, F; Gumuser, F; Uysal, B; Kaya, GC; Koc, M; Ergene, U; Bilgin, E
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    Bone mineral density in girls and boys at different pubertal stages
    Yilmaz, D; Ersoy, B; Bilgin, E; Gümüser, G; Onur, E; Pinar, ED
    Puberty has a key role in bone development. During puberty, several nutritional and hormonal factors play a major role in this process. The aim of this study was to determine the changes in areal bone mineral density (BMD), gonadal steroids, bone formation markers, and growth parameters in healthy Turkish pubertal girls and boys at different pubertal stages. In additional, we aimed to detect the relationship between BMD, sex steroids, and growth parameters, and to reveal the most important determinant of BMD in the pubertal period. BMD of the lumbar spine and total body was performed by dual-energy X-ray absorptiometry (Lunar DPX series) in 174 healthy pubertal children (91 girls, 83 boys), aged 11-15 years. Height and weight were measured. Pubertal stages were assesed. Bone formation markers and gonadal steroids were measured. BMD values significantly increased until stage IV in girls. In boys, BMD values also increased during puberty (P < 0.05), but it was significantly higher in stage IV compared with that in other pubertal stages (P < 0.01). Testosterone levels increased until stage IV in both sexes, particularly in boys. Estrogen levels significantly increased during puberty in girls, whereas it was significantly higher at stage IV in boys (P < 0.001). Bone-specific alkaline phosphatase (BAP) level was higher in early and midpuberty, and decreased in late puberty in girls (P < 0.001). BAP level was higher in stage IV in boys. Osteocalcin level was shown not to change significantly in pubertal stages. There was a modest correlation between BMD values and estrogen and testosterone levels in boys. In girls, there was a correlation between BMD values and estrogen levels only (P < 0.05). Weight was significantly associated with BMD in both sexes (P < 0.05). Estrogen had a significant influence on BMD in boys and girls. In conclusion, bone mass increased throughout puberty in both sexes. Peak bone mass was not achieved in girls, but was obtained at stage IV in boys. Bone formation markers were good predictors of bone mass in girls, but not in boys. Estrogen level made the greatest contribution to bone mineral acquisition in boys and girls. The achievement of peak bone mass was sustained by estrogen in boys. The major independent determinant of BMD in both sexes was weight.
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    Assessment of alveolar epithelial permeability with Tc-99m DTPA aerosol scintigraphy in patients with systemic lupus erythematosus
    Kararmaz, M; Gumuser, F; Pirildar, T; Tarhan, S; Aras, F; Coskun, AS; Bilgin, E
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    Reference Range in Blood-Pool and Liver SUV for 18F-FDG PET/CT
    Parlak, Y; Goksoy, D; Gumuser, G; Bilgin, E
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    The influence of anesthesia- body mass index and chronicity of the injury on the reliability of diagnostic tests for anterior cruciate ligament rupture
    Bilgin, E; Turgut, A; Hancioglu, S; Sariekiz, E; Uzakgider, M; Kalenderer, Ö
    This study aimed to analyze the accuracy and interobserver reliability of the four common diagnostic tests for anterior cruciate ligament (ACL) rupture. The effect of anesthesia, chronicity of the injury and patient's body mass index (BMI) on the reliabilities was also assessed. Patients who underwent arthroscopic knee surgery were examined before the surgery and under anesthesia by three observers categorized based on their experience levels. One hundred two patients were evaluated to determine the accuracy of these tests. Sixty-two patients with ACL rupture were further examined to assess the effect of BMI ( <= 25 kg/m(2), or >25 kg/m(2)) and chronicity ( <= 4 or > 4 weeks) of the injury on reliabilities with using the Fleiss kappa method. The Lachman test performed under anesthesia had the highest sensitivity (100%,100%, and 963%). In contrast, pivot shift and lever sign tests had the lowest sensitivity both in awake (24.2%, 17.7%, 8.1% and 37.1%, 33.8%, 29%) and anesthetized condition (75.8%, 75.8%, 67.7% and 41.9%, 43.5%, 403%). Specificities of the tests except pivot shift were negatively affected when performed under anesthesia. The reliability of the anterior drawer test was perfect under anesthesia. The lever sign test had the highest reliability in the awake condition in patients with a BMI of >25 kg/m(2). Furthermore, the reliabilities of the anterior drawer, Lachman, and pivot-shift tests in awake condition were found to be increased in patients with a chronic injury. Finally, the examiner's experience is not important for the physical diagnosis of ACL rupture.
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    PERFORMANCE OF 2022 ACR/EULAR GPA, EGPA AND MPA CLASSIFICATION CRITERIA IN TURKISH VASCULITIS STUDY GROUP PROSPECTIVE COHORT (TRVAS)
    Bolek, EC; Ayan, G; Bilgin, E; Ediboglu, ED; Duran, E; Kardas, C; Yildirim, TD; Ozdemir, B; Ogüt, TS; Karabacak, M; Cagdas, OS; Yildirim, R; Erpek, E; Ozgur, D; Akleylek, C; Acar, EA; Uludogan, BC; Unaldi, E; Uzun, GS; Ekici, ZOM; Firlatan, B; Kart-Bayram, S; Kutu, ME; Mutlu, MY; Armagan, B; Gercik, O; Bitik, B; Kücük, H; Yilmaz, N; Bilge, NSY; Celik, S; Kilic, L; Kasifoglu, T; Yazici, A; Bes, C; Erden, A; Erbasan, F; Asicioglu, E; Alibaz-Oner, F; Omma, A; Cefle, A; Yazisiz, V; Ozturk, MA; Direskeneli, H; Kiraz, S; Onen, F; Akar, S; Karadag, O

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