Browsing by Author "Bulbul Baytur Y."
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Item Ductus venosus doppler flow velocity after transplacental and non-transplacental amniocentesis during midtrimester(Professional Medical Publications, 2014) Artunc Ulkumen B.; Pala H.G.; Bulbul Baytur Y.; Koyuncu F.M.Objective: We aimed to evaluate ductus venosus Doppler waveforms before and after amniocentesis in order to investigate any effect of amniocentesis on fetal myocardial hemodynamics. We also evaluated the umbilical artery, uterine artery and fetal mid-cerebral artery Doppler waveforms in order to investigate any relationship with ductus venosus Doppler changes. Methods: The study population consisted of 56 singleton pregnancies having genetic amniocentesis. Twenty seven of them had transplacental needle insertion; whereas 29 of them had non-transplacental amniocentesis. Uterine artery, umbilical artery, mid-cerebral artery and ductus venosus pulsatiliy index and resistance index were measured just before and after amniocentesis. Results: Amniocentesis does not cause any significant changes in fetal ductus venosus Doppler waveforms. There is also no significant changes in uterine artery, umbilical artery, mid-cerebral artery pulsatility and resistance index. Conclusion: Amniocentesis-whether transplacental or not- does not cause any significant effect on fetal myocardial hemodynamics.Item The assessment of placental volume and mean gray value in preeclamptic placentas by using three-dimensional ultrasonography(Informa Healthcare, 2015) Artunc Ulkumen B.; Pala H.G.; Uyar Y.; Koyuncu F.M.; Bulbul Baytur Y.Objectives: We aimed to evaluate the placental volume and placental mean gray value in preeclampsia and healthy placentas by using three-dimensional (3D) ultrasonography and Virtual Organ Computer-aided AnaLysis (VOCAL). Methods: This case-control prospective study consisted of 27 singleton pregnancies complicated by preeclampsia and 54 healthy singleton pregnancies matched for gestational age, maternal age and parity. Placental volume and placental volumetric mean gray values were evaluated. The placental volume (cm) was analyzed using the VOCAL imaging program, and 3D histogram was used to calculate the volumetric mean gray value (%). Results: Preeclamptic and control group consisted of 27 (mean age: 28.90±5.95 years, mean gestation: 32.0±4.55 weeks) and 54 (mean age: 29.48±5.78 years, mean gestation: 32.61±4.23 weeks) singleton pregnancies, respectively. Placental volume was significantly smaller in preeclampsia (250.62±91.69 versus 370.98±167.82cm; p=0.001). Volumetric mean gray value of the placenta was significantly higher in preeclampsia (38.24±8.41 versus 33.50±8.90%; p=0.043). Placental volume was significantly correlated with the estimated fetal weight (r=0.319; p=0.003). There was negative significant relation between placental volume and umbilical artery pulsatility index, resistance index and systolic/diastolic ratio (r=-0.244, p=0.024; r=-0.283, p=0.005; r=-0.241, p=0.024, respectively). Conclusions: Placental volume diminishes significantly in preeclampsia, whereas volumetric mean gray values increases. This may reflect the early alterations in preeclamptic placentas, which may help to understand the pathophysiology better. © 2014 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.Item Three-dimensional placental volume and mean grey value: Normal ranges in a Turkish population and correlation with maternal serum biochemistry and Doppler parameters(Informa Healthcare, 2015) Pala H.G.; Artunc Ulkumen B.; Uyar Y.; Koyuncu F.M.; Bulbul Baytur Y.The aim of this study is to evaluate the relationship between three-dimensional (3D) ultrasound measurements of placenta at 11136 weeks' gestation and maternal serum levels of pregnancy associated plasma protein-A (PAPP-A), free beta human chorionic gonadotrophin (fβhCG), Doppler parameters in early pregnancy. This prospective study consisted of 334 singleton pregnancies at 11136 weeks' gestation. Placental volume and placental volumetric mean grey values were evaluated. The placental volume (cm3) was analysed using the Virtual Organ Computer-aided AnaLysis (VOCAL) imaging program and 3D histogram was used to calculate the volumetric mean grey value (%). Mean maternal age was 28.35 ± 7.55. Mean gestational age was 12.29 ± 0.68 weeks. Placental volume was 77.04 ± 35.74 cm3. Mean grey value of the placenta was 34.38 ± 8.02%. Correlation analysis revealed that placental volume was significantly correlated with the crown-rump length (r = 0.173, p = 0.002), gestational week (r = 0.116, p = 0.036), ductus venosus pulsatility index (r = 0.101, p = 0.04) and maternal weight (r = 0.099, p = 0.037). There was a significant relation between the mean grey value of the placenta and maternal age (r = 0.131, p = 0.02), nuchal translucency (r = 0.109, p = 0.048), PAPP-A (r = 0.108, p = 0.04) and fβhCG (r = 0.104, p = 0.042). Volumetry of the placenta can be carried out with a high percentage of 1st trimester pregnancies. Volumetry during the 1st trimester could be helpful because of the less advanced state of placentation. This examination is easy to perform and the measurements can be acquired correctly and quickly. © 2015 Informa UK, Ltd.Item Foetal axillary lymphangioma with ipsilateral pes equinovarus: Pitfalls in sonographic differential diagnosis (Axillary Lymphangioma & Pes Equinovarus)(Taylor and Francis Ltd, 2015) Bulbul Baytur Y.; Artunc Ulkumen B.; Pala H.G.[No abstract available]Item The alteration in placental volume and placental mean grey value in growth-restricted pregnancies assessed by 3D ultrasound(Taylor and Francis Ltd., 2015) Artunc Ulkumen B.; Pala H.G.; Uyar Y.; Koyuncu F.M.; Bulbul Baytur Y.We aimed to evaluate the volumetric and echogenic alterations in placentas between the intrauterine growth restriction (IUGR) and normal pregnancies using three-dimensional ultrasound and virtual organ computer-aided analysis (VOCAL) software. This case-control prospective study consisted of 48 singleton pregnancies complicated by IUGR and 60 healthy singleton pregnancies matched for maternal age, gestational age and parity. Placental volume (PV) and placental volumetric mean grey values (MGV) were evaluated. PV (cm3) was analysed using the VOCAL imaging analysis program, and 3D histogram was used to calculate the volumetric MGV (%). PV was 278.50 ± 63.68 and 370.98 ± 97.82 cm3 in IUGR and control groups, respectively (p = 0.004). MGV of the placenta was 38.24 ± 8.41 and 38.24 ± 8.41 in IUGR and control groups, respectively (p = 0.30). receiver operator curve (ROC) curve analysis revealed that area under curve was 0.731 for PV. Correlation analysis revealed that PV was significantly associated with estimated fetal weight (r = 0.319, p = 0.003), biparietal diameter (r = 0.346, p = 0.002), head circumference (r = 0.269, p = 0.019), abdominal circumference (r = 0.344, p = 0.002) and femur length (r = 0.328, p = 0.004). PV was inversely related to the umbilical artery pulsatility index (r =-0.244, p = 0.017). To the best of our knowledge, this is the first study evaluating volumetric MGV in IUGR placentas by comparing them with healthy pregnancies. Our study showed that PV diminishes significantly in IUGR pregnancies, whereas volumetric MGV does not alter significantly. © 2015 © 2015 Taylor & Francis Group, LLC.