Browsing by Author "Buyuksu, C"

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    Effects of extracorporeal shockwave lithotripsy at different stages of pregnancy in the rabbit
    Gumus, B; Lekili, M; Kandiloglu, AR; Isisag, A; Temeltas, G; Nazli, O; Buyuksu, C
    Although SWL is now the most common treatment modality for urinary tract stone disease, it is not regarded as a safe method for pregnant patients because of its potential harmful effects on fetus, Using a rabbit model, Re investigated whether SWL might cause fetal injury when administered at various developmental stages. Two groups of pregnant rabbits were given 1000 shockwaves either early or late in the gestational period, Time-matched controls did not receive shockwaves, After spontaneous labor, all newborn rabbits were counted, weighted, and measured, and specimens were taken from organs and examined histopathologically. The numbers, weights, and diameters of the newborns in each group were similar, There was no notable histopathologic finding in the heart and brain specimens of any of the newborns, whereas noticeable congestion and multiple focal intraparanchymal microhemorrhages were found in lungs, livers, and kidneys of the animals that had been exposed to shockwaves early in gestation, In conclusion, this study shows that SWL is not a safe treatment in early pregnancy.
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    Testicular sperm retrieval method
    Gümüs, BH; Atesci, YZ; Ucer, O; Karatas, TC; Buyuksu, C; Nese, N; Kandiloglu, AR
    This research was conducted to evaluate the effects of a transverse vs. longitudinal incision for testicular sperm retrieval. Rats were divided into 4 groups: I: control, II: sham operation, III: longitudinal incision TSRM, IV: transverse incision TSRM. Group II (sham operation) had a dissection of left testis/spermatic cord, then closure of wound. Group III underwent dissection of left testis, then a longitudinal incision (15 mm long) of testis, which was fully opened then closed again and sutured with 5-0 Vicryl (R) sutures. Group IV underwent dissection of the left testis, opening of the testis with a transverse incision, then closure with 5-0 Vicryl (R). The seminiferous tubule diameter was 0.118-0.224 mm in all groups. inflammation and abscess formation occurred in one testis each in the sham and longitudinal incision groups, and in two testes in the transverse incision group. There were no differences in histopathology or scoring between the longitudinal and the transverse incision.