Browsing by Author "Can E."

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    Does the finding of a indeterminate mass lesion in screening CT result in kidney loss and is postoperative follow-up necessary in renal oncocytomas? A retrospective study
    (2006) Özkol M.; Can E.; Zorlu F.; Gümüş B.
    Objective. Sixteen patients who were operated on with a preoperative diagnosis of renal tumor were diagnosed with renal oncocytoma between 1991 and 2004. The reliability of preoperative diagnosis, the role of screening CT in organ preservation and the need for follow-up for renal oncocytomas are discussed in the light of literature findings. Material and methods. Among 345 patients diagnosed with renal tumors in the previous 13 years, the clinical and radiological features of the 16 patients with renal oncocytomas and the results during the postoperative follow-up period were evaluated in this retrospective study. The female:male ratio was 4.3. Two of the patients complained of hematuria whereas the other 14 experienced lumbocostal pain. The mean dimensions of the tumors on CT scans were 5.7±2.88 cm. Central fibrous scarring existed in three patients. Two patients underwent tumor enucleation, three underwent partial nephrectomy and 11 underwent radical nephrectomy. Results. Screening CT could not achieve a precise preoperative differential diagnosis from malignant renal mass. The organ preservation ratio was approximately 1:3 based on the radiological diagnosis. Screening CT scans showed oncocytomas with diameters greater than those reported in the literature, indicating a need for urgent nephrectomy. No recurrences, metastases or deaths due to renal oncocytoma were observed in the postoperative follow-up period (mean 6.7±4 years; range 1-13 years). Conclusions. Preoperative diagnosis of renal oncocytoma is very difficult. The postoperative follow-up period in our series was 13 years, which is significantly longer than the duration proposed in the literature. © 2006 Taylor & Francis.
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    Prevalence of Metabolic Syndrome and Its Association with Erectile Dysfunction Among Urologic Patients: Metabolic Backgrounds of Erectile Dysfunction
    (2007) Bal K.; Öder M.; Şahin A.S.; Karataş C.T.; Demir Ö.; Can E.; Gümüş B.H.; Özer K.; Şahin O.g.; Esen A.A.
    Objectives: To identify the prevalence of metabolic syndrome (MS) and its association with erectile dysfunction (ED) among urologic patients. Methods: The study population consisted of 393 male patients aged 40 to 70 years, who were admitted to the urology clinics of four different institutions from February to March 2005. The waist circumference (WC) and triglyceride (TG) and high-density lipoprotein (HDL) cholesterol levels were measured. Patients were divided into two groups: group 1 consisted of patients with a WC greater than 102 cm, and group 2 consisted of patients with a WC of less than 102 cm. The erectile status of the two groups was compared. Results: Of the 393 patients, 157 (39.9%) had MS. Of the 393 patients, 124 with MS (79%) and 146 without MS (61.9%) had ED. The presence of MS was significantly associated with ED (P <0.001). In the presence of an increased WC with normal serum HDL and TG levels, the relative risk of ED was 1.94. If the patient with an increased WC had a pathologic level of HDL or TG, the relative risk of ED increased up to 2.97-fold. The relative risk of ED in the presence of an increased WC, together with pathologic levels of HDL and TG, was 3.38. Conclusions: In our study, MS was strongly associated with ED. Fasting blood glucose levels, hypertension, and WC are the most significant risk factors predicting the risk of ED. A more pronounced increase in ED risk in the presence of abdominal obesity, together with altered TG and HDL cholesterol levels, may indicate a special metabolic background of ED regarding lipid metabolism. © 2007 Elsevier Inc. All rights reserved.
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    Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome
    (2009) Demir O.; Akgul K.; Akar Z.; Cakmak O.; Ozdemir I.; Bolukbasi A.; Can E.; Gumus B.H.
    Introduction. The purpose of this study was to investigate the association between severity of lower urinary tract symptoms LUTS, erectile dysfunction ED and metabolic syndrome. Methods. Our study population included a consecutive series of 190 patients with LUTS International Prostate Symptom Score-IPSS >7 with or without manifestations of the metabolic syndrome. The diagnoses of diabetes mellitus and hypertension were obtained from the patient's medical history. Data on blood pressure, waist measure, body height and weight were collected and body mass index were calculated. Patients were assessed based on the International Index of Erectile Function IIEF for ED and IPSS and IPSS-Quality of Life for LUTS. Blood samples were drawn from fasting patients to determine, fasting blood glucose FBG, triglycerides, HDL-cholesterol and serum total testosterone levels. Results. In severe LUTS patient group, IIEF erectile function domain scores were significantly lower than moderate LUTS patient group p < 0.05. Multiple logistic regression analysis confirmed that presence of ED was the most predictor of severe LUTS. The prevalence of metabolic syndrome was higher in patients with severe LUTS 26vs. 46, p 0.009. The severe form of the LUTS was significantly correlated with waist circumference >102 cm p < 0.05, blood pressure ≥13085 mmHg p < 0.05 and FBG >110 mgdl p < 0.01. Conclusion. Obesity, high plasma level of FBG and hypertension constitute risk factors for the development of severe LUTS. Metabolic syndrome may play a key role in the pathogenesis in both ED and LUTS. Presence of ED is the most predictor of severe LUTS. © 2009 Informa UK Ltd.
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    Erectile function and late-onset hypogonadism symptoms related to lower urinary tract symptom severity in elderly men
    (2013) Bozkurt O.; Bolat D.; Demir O.; Ucer O.; Şahin A.; Ozcift B.; Pektaş A.; Turan T.; Gümüş B.H.; Can E.; Bolukbasi A.; Erol H.; Esen A.
    The aim of this study was to evaluate the relationship between lower urinary tract symptoms (LUTSs), erectile dysfunction (ED) and symptomatic late-onset hypogonadism (SLOH) in ageing men in the Aegean region of Turkey. Five hundred consecutive patients >40 years old who had been in a steady sexual relationship for the past 6 months and were admitted to one of six urology clinics were included in the study. Serum prostate-specific antigen and testosterone levels and urinary flow rates were measured. All patients filled out the International Prostate Symptom Score and Quality of Life (IPSS-QoL), International Index of Erectile Function (IIEF) and Aging Males' Symptoms (AMS) scale forms. Of the patients, 23.9% had mild LUTSs, 53.3% had moderate LUTSs and 22.8% had severe LUTSs. The total testosterone level did not differ between groups. Additionally, 69.6% had ED. The presence of impotence increased with increasing LUTS severity. Symptomatic late-onset hypogonadism (AMS >27) was observed in 71.2% of the patients. The prevalence of severe hypogonadism symptoms increased with the IPSS scores. A correlation analysis revealed that all three questionnaire scores were significantly correlated. In conclusion, LUTS severity is an age-independent risk factor for ED and SLOH. LUTS severity and SLOH symptoms appear to have a strong link that requires etiological and biological clarification in future studies. © 2013 AJA, SIMM & SJTU. All rights reserved.