Browsing by Author "Canda, AE"

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    A Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study
    Keske, M; Canda, AE; Karadag, MA; Çiftçi, H; Erturhan, S; Kactan, C; Soytas, M; Özkaya, F; Ozbey, I; Ordek, E; Atmaca, AF; Yildirim, A; Sahin, S; Colakoglu, Y; Boylu, U; Erol, B; Caskurlu, T; Kiremit, MC; Cakici, OU; Sonmez, G; Kiliçarslan, H; Akbulut, Z; Kaygisiz, O; Bedir, S; Vuruskan, H; Bozkurt, YE; Aydin, HR; Oguz, U; Basok, EK; Gumus, BH; Tuncel, A; Aslan, Y; Hamidi, N; Müslümanoglu, AY; Dinçer, M; Balbay, D; Albayrak, S; Laguna, MP
    Introduction: Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. Methods: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible with testicular dysgenesis syndrome. Histology was categorized per size and risk groups. Results: TSS was performed in 83 patients (86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 masses were benign and TGCTs, respectively. No statistical differences were observed in mean age (30.9 +/- 10.32 years), pathological tumor size (14.67 +/- 6.7 mm) between risk groups or between benign and malignant tumors (p = 0.608). When categorized per risk groups, 22 (73.3%) and 4 (7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups, respectively. Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5 +/- 22.7 months, no patient developed systemic disease. Local recurrence was detected in 5 patients and received radical orchiectomy. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No erectile dysfunction was reported in patients with benign lesions. Conclusion: TSS is a safe and feasible approach with adequate cancer control, and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling.