Browsing by Author "Canda E."

Now showing 1 - 6 of 6
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    An evaluation of quality of life of mothers of children with enuresis nocturna
    (2008) Egemen A.; Akil I.; Canda E.; Ozyurt B.C.; Eser E.
    The aim of this study was to evaluate the impact of enuresis nocturna on quality of life of the mothers. Mothers who have a child with monosymptomatic nocturnal enuresis (n=28) and mothers who have a child without any health problems (n=38) were enrolled in the study. Groups were in balance for background variables (child's age, gender, and number of siblings; mother's age, marital status, highest year of education completed, and occupation; presence of health insurance; and type of residence). Short-Form Health Survey (SF-36) Questionnaire, the Beck Depression Inventory (BDI), and Spielberg's State-Trait Anxiety Inventory (STAI) were applied to all mothers. The mothers of children with enuresis had significantly lower quality-of-life scores in the SF-36 for the bodily pain (p=0.015) and role emotional (p=0.014) subscales. We observed significant difference between groups according to BDI; mean score was higher in mothers who have a child with enuresis nocturna (p=0.017). There was no significant difference between groups according to the STAI. Significant differences according to bodily pain and role emotional subscales of SF-36, and the BDI scores, show that the mothers were negatively affected by having a child with monosymptomatic nocturnal enuresis. © IPNA 2007.
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    Co-existence of chronic renal failure, renal clear cell carcinoma, and Blau syndrome
    (2010) Akil I.; Ozguven A.; Canda E.; Yilmaz O.; Nese N.; Ozkol M.; May S.; Franke A.; Cirak S.
    Blau syndrome is a rare, multisystem, autosomal-dominant, and granulomatous disorder caused by susceptibility variants in the NOD2 gene. We describe here a 14-year-old girl with Blau syndrome with incidentally diagnosed renal carcinoma. The index case presented with growth retardation and recurrent symmetric arthritis. Her clinical symptoms included bilateral cataract due to recurrent uveitis, camptodactyly, and persistent erythematous rash with ichthyosis. Her two sisters and her mother were affected with combinations of these conditions-symmetric polyarthritis, uveitis, and skin involvement- suggesting an autosomal dominant trait. The index case developed a chronic renal insufficiency, and an abdominal computerized tomography scan revealed a 2.5-cm mass in the left kidney. The histopathological examination showed renal clear cell carcinoma, chronic tubulointerstitial nephritis, and giant cell granulomas in both the tumor and non-neoplastic renal tissue. Granulomatous inflammation was observed in the skin biopsy specimen. The patient was diagnosed with Blau syndrome based on her family history, uveitis, granulomatous inflammation proved by skin biopsy, and polyarthritis. Sequencing of the NOD2 gene showed a heterozygous p.R334Q mutation in all affected family members. To the best of our knowledge, this is the first reported case of a patient with Blau syndrome accompanied by chronic renal failure and renal carcinoma. © 2010 IPNA.
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    Changes in quantitative ultrasound in preterm and term infants during the first year of life
    (2011) Tansug N.; Yildirim S.A.; Canda E.; Özalp D.; Yilmaz O.; Taneli F.; Ersoy B.
    Since most of in utero bone mass accretion occurs during the third trimester and postnatal need for bone nutrients is increased, preterm infants have an increased risk of low bone mass. Early identification of the risk is of crucial importance. Quantitative ultrasound, which is a relatively inexpensive, portable, noninvasive, and radiation-free method, gives information about bone density, cortical thickness, elasticity and microarchitecture. The aim of this study was to obtain quantitative ultrasound measurements of tibial speed of sound of preterm and term infants and to assess clinical factors associated with these measurements during the first year of life. Seventy-eight preterm and 48 term infants were enrolled in this study. Measurements were made on the 10th day of life in both groups, and were repeated on the 2nd, 6th and 12th months for preterm infants and on the12th month for the term infants. Speed of sound on preterm infants was significantly decreased on the 2nd month but significantly increased on the 12th month (P = 0.00). Comparing speed of sound of term and preterm infants, 10th day measurements were significantly different (P = 0.00), but there was not any significant difference between the 12th month values (P = 0.26). There was not any relation between biochemical parameters and speed of sound. The technique has potential clinical value for assessment of bone status. Further studies with long term follow up are needed to evaluate the value of quantitative ultrasound with other bone markers to predict the risk of fracture. © 2010 Elsevier Ireland Ltd. All rights reserved.
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    Assessment of toll-like receptor-4 gene polymorphism on pyelonephritis and renal scar
    (2012) Akil I.; Ozkinay F.; Onay H.; Canda E.; Gumuser G.; Kavukcu S.
    The aim of this study was to evaluate the effect of the TLR-4 gene TLR4 c.896A
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    Trigliserit nedir? Normal fizyolojideki yeri nedir?
    (Turkish Society of Cardiology, 2017) Çetinkalp Ş.; Koylan N.; Özer N.; Onat A.; Gökhan Özgen A.; Lale Koldaş Z.; Güven G.S.; Özdoğan Ö.; Karşıdağ K.; Yiğit Z.; Kayıkçıoğlu M.; Tokgözoğlu L.; Can L.H.; Tartan Z.; Kültürsay H.; Karpuz B.; Kırılmaz B.; Ersanlı M.; Ural D.; Erbakan A.N.; Oğuz A.; Kayıkçıoğlu Ö.R.; Temizhan A.; Sansoy V.; Ceyhan C.; Öngen Z.; Bayram F.; Örem C.; Sönmez A.; Beyaz Ş.; Ükinç K.; Yürekli B.Ş.; Çoker M.; Canda E.; Şimşir I.Y.
    [No abstract available]
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    The relationship between ultrasonographically measured testicular volumes and cord blood inhibin B concentrations in healthy term male neonates
    (Elsevier B.V., 2023) Ersoy B.; Ovalı G.Y.; Canda E.; Onur E.; Özyurt B.C.; Tansuğ N.
    Serum inhibin B (INHB) concentrations are associated with testicular volumes (TV) in all periods of childhood. The aim of the study was to investigate the relationship between TV measured by ultrasonography (US) and cord blood inhibin B and total testosterone (TT) concentrations, stratified by mode of delivery. In total 90 male infants were included. Testes of healthy, term newborns were evaluated by US on the third day after delivery. TV were calculated using two formulae: The ellipsoid formula [length (mm) × width (mm2) × π/6] and Lambert formula [length (mm) x width (mm) x height (mm) x 0.71]. Cord blood was taken for the determination of total testosterone (TT) and INHB. TT and INHB concentrations were evaluated according to TV percentiles (<10th, 10th-90th, >90th). There was a strong positive correlation between mean TV calculated with both formulae by percentile group (r = 0.777, r = 0.804, r = 0.846; p < 0.001). Cord blood INHB, but not TT were significantly lower in newborns with TV < 10th percentile compared to those with TV between 10 and 90th percentile and > 90th percentile (p < 0.05). There was a positive correlation between left and right TV calculated by either formula, and cord blood INHB (r = 0.212, 0.313, 0.320, 0.246, p < 0.05), not TT. There was no significant difference between hormones and TV when grouped by mode of delivery (p > 0.05). The Lambert and ellipsoid formulas are equally reliable in calculating neonatal testicular by ultrasound. INHB concentration is high in cord blood and positively correlated with neonatal TV. Cord blood INHB concentration may be an indicator for early detection of testicular structure and function disorders in neonates. © 2023 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn