Browsing by Author "Celik, G"

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    Extrapulmonary involvement in patients with sarcoidosis in Turkey
    Okumus, G; Musellim, B; Cetinkaya, E; Turker, H; Uzaslan, E; Yenturk, E; Uzun, O; Saglam, L; Kumbasar, OO; Celik, G; Annakkaya, AN; Altiay, G; Tabak, L; Sakar, A; Kiter, G; Erturan, S; Turktas, H; Yalniz, E; Akkoclu, A; Ogus, C; Dogan, OT; Ozkan, M; Aktogu, S; Uzel, I; Ongen, G
    Background and objective: Extrapulmonary sarcoidosis is common, and is almost always associated with concomitant thoracic involvement. Extrapulmonary manifestations vary on the basis of gender, age at presentation and ethnicity. The aim of this study was to investigate extrapulmonary involvement in patients with sarcoidosis in Turkey. Methods: This study was conducted by Turkish Thoracic Society Clinical Problems Study Group. New cases of sarcoidosis between 1 June 2004 and 31 May 2006 were recorded on electronic case record forms sent to all potential investigators and information about extrapulmonary involvement was collected. Results: One hundred and nineteen of 293 patients (83 female, 36 male, mean age = 45 +/- 12 years) had extrapulmonary involvement in this study (40.6%). The median time to diagnosis was 6 months and this was longer than patients with just thoracic sarcoidosis (P = 0.001). Extrapulmonary symptoms were present in 181 (61.8%) patients, and skin lesions, arthralgia and back pain were the commonest (33.4%, 20.8% and 16.4%, respectively). Incidence of organ involvement was independent of age with the exception of ocular involvement, which was higher in those under the age of 40 years (P = 0.007). Conclusions: Skin and peripheral lymph node involvement were the most common sites of extrapulmonary involvement and ocular involvement was more common in those under the age of 40 years in patients with sarcoidosis in a Turkish population.
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    Epidemiological features of Turkish patients with sarcoidosis
    Musellim, B; Kumbasar, OO; Ongen, G; Cetinkaya, E; Turker, H; Uzaslan, E; Yenturk, E; Uzun, O; Saglam, L; Celik, G; Okumus, G; Annakkaya, AN; Altiay, G; Tabak, L; Sakar, A; Kiter, G; Erturan, S; Turktas, H; Yalniz, E; Akkoclu, A; Ogus, C; Dogan, OT; Ozkan, M; Aktogu, S; Uzel, I
    Epidemiological characteristics of sarcoidosis differ according to geographical distribution. The aim of our study was to disclose epidemiological characteristics in our country. The data was collected from investigators, who sent information on newly-diagnosed patients via internet. In 2 years 198 female and 95 mate patients were enrolled to the study (f/m:2.08). Mean age of patients was 44 +/- 13 years (17-90). Mean age of mate patients was 38 12 while mean age of female patients was 48 13 (p < 0.001). 73.4% of patients were nonsmokers (85.4% of females; 48.4% of mates; (p < 0.001)). About 50% of our 293 patients were housewives. Familial sarcoidosis was found in 3 patients' first degree relatives. Estimated annual incidence of sarcoidosis for Turkey was calculated as 4 per 100,000 person. According to our study, 2/3 of sarcoidosis patients were women; mean age of patients was 45 and the disease began 10 years later in female patients. 80% of patients were nonsmokers; negative relation between sarcoidosis and smoking was evident especially in women. Familial sarcoidosis frequency was lower compared to other studies in the literature. There was no occupational exposure history in our patients. Our incidence rate, is similar with the results of other European studies. (C) 2008 Elsevier Ltd. All rights reserved.
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    Effect of Impairment on the Prevalence and Comorbidities of Attention Deficit Hyperactivity Disorder in a National Survey: Nation-Wide Prevalence and Comorbidities of ADHD
    Ercan, ES; Unsel-Bolat, G; Tufan, AE; Demirkaya, SK; Bilac, O; Celik, G; Kiliç, BG; Ardic, UA; Sapmaz, SY; Aksu, H; Tahiroglu, AY; Karacetin, G; Tural, U; Aktepe, E; Arman, AR; Basgül, S; Coskun, M; Dursun, OB; Durukan, I; Fis, NP; Gençoglan, S; Gökçen, C; Gokten, ES; Görker, I; Görmez, V; Gündogdu, ÖY; Hesapçioglu, ST; Kandemir, H; Mutluer, T; Nasiroglu, S; Özcan, Ö; Sahin, N; Toros, F; Yazici, IP; Yazici, KU; Yulaf, Y; Yüksel, T; Bilgic, A; Altun, H; Akdemir, D; Mazlum, B; Memik, NÇ; Özdemir, DF; Üneri, Ö; Ünal, F
    Objective: This study aimed to determine the prevalence and comorbidities of attention-deficit hyperactivity disorder (ADHD) by evaluating a large-scale nation-wide sample of children. Method: The inclusion criterion was being enrolled as a 2nd, 3rd, or 4th-grade student. A semi-structured diagnostic interview (K-SADS-PL), DSM-IV-Based Screening Scale for Disruptive Behavior Disorders, and assessment of impairment (by both parents and teachers) were applied to 5,842 participants. Results: The prevalence of ADHD was 19.5% without impairment and 12.4% with impairment. Both ADHD with and without impairment groups had similar psychiatric comorbidity rates except for oppositional defiant disorder (ODD) and conduct disorder (CD) diagnoses. Impairment in the ADHD group resulted in significantly higher ODD and CD diagnoses. Conclusion: Even when impairment is not described, other psychiatric disorders accompany the diagnosis of ADHD and may cause impairment in the future. Impairment in the diagnosis of ADHD significantly increases the likelihood of ODD and CD.