Browsing by Author "Dündar, PE"
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Item Risk factors for delaying treatment seeking in obsessive-compulsive disorderDemet, MM; Deveci, A; Taskin, EO; Dündar, PE; Ermertcan, AT; Demet, SM; Bayraktar, D; Öztürkcan, SBackground: Despite the multiple alternatives of treatment, it is well known that patients with obsessive-compulsive disorder (OCD) delay seeking treatment. In this study, the aim was to determine the risk factors for delaying treatment seeking in OCD patients. Methods: The sample consisted of 132 OCD who completed the Yale-Brown Obsessive-Compulsive Scale, Yale-Brown Obsessive-Compulsive Scale Symptom Checklist, and Beck Depression Inventory. Results: In univariate analyses with risk evaluation, income level, being single or divorced, having a history of psychiatric treatment, poor insight for the symptoms, and obsessions of hoarding were the variables that were found to be significant. In the regression model, history of psychiatric treatment and duration of OCD were the 2 variables that remained statistically significant. Conclusion: This was the first study wherein the sample included patients who were recruited from a nonpsychiatric department: the dermatology clinic. Application to dermatology has not been determined as a risk factor for delaying treatment seeking in OCD patients. (c) 2010 Elsevier Inc. All rights reserved.Item THE RELATIONSHIP BETWEEN GENDER AND DEPRESSION, SELF-ESTEEM, HOPELESSNESS, SUBMISSIVE ACTS, GUILT, SHAME AND ANGER IN ADOLESCENTSÖzmen, E; Özmen, D; Çetinkaya, AÇ; Taskin, EO; Dündar, PELiterature Review and Objective: Although there were a number of research findings on gender differences in mental health problems, it is not known that it is a universal phenomenon or not. The purpose of this study was to investigate the relationship between gender and depression, self-esteem, hopelessness, submissive acts, guilt, shame and anger in Turkish adolescents. Methods: A cross-sectional survey of 1185 ninth-grade Turkish adolescents aged 14-19 was conducted. 708 (59.7 %) of the students were male and the mean age of students was 15.53+/-0.72. Hopelessness was measured by using Beck Hopelessness Scale (BHS), self-esteem was measured by using the Rosenberg Self-Esteem Scale (SES), depression was measured by using Children's Depression Inventory (CDI), guilt and shame was measured by using Guilt and Shame Scale (GSS), submissive acts was measured by using Submissive Acts Scale (SAS), anger was measured by using The State-Trait Anger Scale (STAS). Student's t-test was used to find out the relationship between gender and depression, self-esteem, hopelessness, submissive acts, guilt, shame and anger in adolescents. Results: The findings indicate that the mean score of the SAS and BHS, anger control subscale of STAS of the boys were higher than that of the girls and the mean score of the CDI, guilt subscale of GSS, shame subscale of GSS, SES, trait anger subscale of STAS, anger-in subscale of STAS and anger-out subscale of STAS of the girls were higher than that of the boys. While there were statistically significant associations between gender and the SAS, BHS, CDI, guilt subscale of GSS, shame subscale of GSS, trait anger subscale of STAS, anger-out subscale of STAS and anger control subscale of STAS mean scores; no relationship was found between gender and the anger-in subscale of STAS and SES mean scores. Conclusion: The results of this study point out that there are gender differences in hopelessness, depression, guilt, shame, submissive acts and anger levels but not in self-esteem levels in Turkish adolescents. The findings suggest that psychological gender differences are seen not only in individualistic societies, but also in collectivistic societies.Item Antibody Sustainability in SARS-CoV-2 Healthcare Professionals' Patient CohortEser, E; Akar, SS; Akçali, S; Ecemis, T; Dündar, PE; Çiçek, K; Akman, D; Tüzün, E; Erkekoglu, GS; Buran, ZC; Arikan, ZÖÖ; Yalçin, FKIn this study, it was aimed to evaluate one-year follow-up of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) specific antibodies formed against the virus binding site, in a coronavirus disease-2019 (COVID-19) positive case cohort (n= 413) between the period March 2020 to December 2020 in Manisa Celal Bayar University Hospital, until July 2021. SARS-CoV-2 antibodies were determined by the chemiluminescent enzyme immunoassay (CLIA) method. Values of 1.0 and above were considered positive. Chi-square tests and Joinpoint regression analysis (version 4.7.0) were used in the statistical analyses. The mean age of the participants was 34.9 +/- 9.3 and 60.2% of them were women. Between 21-30 days after the diagnosis of COVID-19, total antibody level was above the threshold value in 72.2% (n= 126) of the participants, while this rate increased to 79.1% (n= 240) in 31-60 day interval. In the following period, this rate decreased to 38.8% (n= 108) in days 211st to 240th. Antibody response could not be detected in 76 (20.7%) of 367 employees who have initially been followed up. The percentage of total antibody positivity prevalence ranged from 98.9% to 96.1% in the 31-210th day after diagnosis, in the follow-up of 291 employees whose total antibody positivity was detected after diagnosis. According to the results of the Joinpoint regression analysis, after the diagnosis of COVID-19, the curve showing the percentage of antibody positivity was broken at two points: The first breaking point was observed in 181-210th days (6-7 months) (p= 0.069), and the second breaking point was in 271-300th days (9-10 months) (p< 0.001). As a result, the highest antibody positivity rates were detected after the 30th day of the disease onset and antibody positivity was maintained in the first seven months after diagnosis; the antibody positivity rate decreased to 25% at the end of the first year.Item The prevalence of low back pain and its relationship with household jobs and other factors in a group of women in a rural area in ManisaDündar, PE; Özyurt, BC; Özmen, DThe aims of this cross-sectional study were to determine the prevalence of low back pain and to evaluate the effects of household jobs on low back pain in women living in a rural setting in Manisa. Study population is consisted of 302 women and cluster sampling is performed according to percentage of health center district populations. Participation ratio of this study was 89.1%. Univariete and multivariete risk approach in 95% confidence interval and t test were performed in data analysis. Brief Disability Questionnaire was applied to the study group. Life time and point prevalence of low back pain were determined 79.2% and 34.9% of the study group. Low back pain risk in 95 % CI was higher in wrong posture during ironing, heavy load lifting, overweight/obesity and disability 2.2 (1.1-4.5), 4.5 (2.1-9.2), 3.8 (1.7-8.3) and 9.2 (4.3-19.7) times respectively. For preventive health measures it is necessary to apply ergonomic working conditions and to give appropriate postural habits to women.Item Relationship Between Duodenal Histopathology and Strong Positive Tissue Transglutaminase Antibodies in Children with Celiac DiseaseDogan, G; Ayhan, S; Yilmaz, B; Appak, YÇ; Dündar, PE; Ecemis, T; Ünal, F; Kasirga, EIntroduction: In celiac disease (CD) strong positive tissue transglutaminase antibody (TTGA) levels (> 100 U/A) have been shown to almost always indicate villous atrophy. The aim of this study is to determine the sufficiency of >= 100 U/A Ig A type TTGA levels for diagnosis of CD. Materials and Methods: Results from duodenum biopsy performed due to positive TTGA in 197 children were retrospectively examined. IgA TTGA levels had a positive value of > 18 U/A. Increases of 5 times or more than this threshold value (>= 100 U/A) are accepted as strong positivity. CD diagnosis was made according to ESPGHAN criteria. A modified Marsh stage >= 2 was accepted as significant for CD. Results: Of the cases, 129 were female (65.5%) and 68 were male (34.5%). Duodenum histopathology was compatible with Marsh 0 for 1 case (0.5%), Marsh 2 for 17 cases (8.6%), Marsh 3a for 41 (20.8%), Marsh 3b for 81 (41.4%) and Marsh 3c for 57 (28.9%). The TTGA levels of 64 of the 197 cases (32.5%) were >= 100 U/A. In cases with strong positivity for TTGA the duodenum histology was compatible with Marsh 3 (villous atrophy) for 63 and Marsh 0 (normal histology) for 1 case (type 1 diabetic and asymptomatic for CD). For Marsh 3c TTGA levels >= 100 U/A had a sensitivity of 85.96% (95% CI: 74.2-93.7%), specificity of 89.29% (95% CI: 82.9-93.8%), positive predictive value of 76.56% (95% CI: 64.3-86.2%) and negative predictive value of 93.9% (95% CI: 88.4-97.3%). Conclusions: This study showed that positive IgA TTGA levels (>= 100 U/A) were almost always accompanied by Marsh 3 duodenal histopathological changes. Diagnosis of CD without biopsy may miss certain accompanying diseases, however in some cases with advanced examinations CD may be diagnosed by pediatric gastroenterology specialists without endoscopy.Item The knowledge and attitudes of breast self-examination and mammography in a group of women in a rural area in western TurkeyDündar, PE; Özmen, D; Öztürk, B; Haspolat, G; Akyildiz, F; Çoban, S; Çakiroglu, GBackground: Breast cancer appears to be a disease of both the developing and developed worlds. Among Turkish women, breast cancer is the second leading cause of cancer-related deaths. The aims of this cross-sectional study were to determine levels of knowledge about breast cancer and to evaluate health beliefs concerning the model that promotes breast self-examination (BSE) and mammography in a group of women aged 20 - 64 in a rural area of western Turkey. Methods: 244 women were recruited by means of cluster sampling in this study. The questionnaire consisted of sociodemographic variables, a risk factors and signs of breast cancer form and the adapted version of Champion's Health Belief Model Scale (CHBMS). Bivariate correlation analysis, Chi square test, Mann-Whitney U test and logistic regression analysis were performed throughout the data analysis. Results: The mean age of the women was 37.7 +/- 13.7. 49.2% of women were primary school graduates, 67.6% were married. Although 76.6% of the women in this study reported that they had heard or read about breast cancer, our study revealed that only 56.1% of them had sufficient knowledge of breast cancer, half of whom had acquired the information from health professionals. Level of breast cancer knowledge was the only variable significantly associated with the BSE and mammography practice ( p = 0.011, p = 0.007). BSE performers among the study group were more likely to be women who exhibited higher confidence and perceived greater benefits from BSE practice, and those who perceived fewer barriers to BSE performance and possessed knowledge of breast cancer. Conclusion: By using the CHBMS constructs for assessment, primary health care providers can more easily understand the beliefs that influence women's BSE and mammography practice.Item Six Clinical Predictors for Intractable Childhood EpilepsyAyca, S; Oral, RD; Dündar, PE; Polat, MAim: This study aimed to determine the significance of six clinical predictors associated with medically intractable childhood epilepsy. Materials and Methods: A retrospective cohort study was conducted. A total of 241 children with diagnosed epilepsy were recruited and divided into two groups: 61 patients with intractable epilepsy, and the other 180 patients who responded well to antiepileptic drugs. We investigated seizure semiology, etiology of epileptic encephalopathy, EEG abnormalities and defined the odds ratios (ORs) of predictor factors for intractable childhood epilepsy; age of seizure onset, asphyxia, neonatal intensive care unit (NICU) history, consanguineous marriage, abnormal neuro-imaging, neuropathologic exam, prematurity, parents' seizure history. Results: According to logistic regression analysis, the major risk factors for intractable childhood epilepsy are (1) neuropathologic examination p=0.000, OR= 58.28 CI= 23.95-141.63; (2) abnormal neuro-imaging p=0.000, OR= 37.55 CI= 16.41-85.94 (3) age of seizure onset p=0.001, OR= 9.43 confidence interval (CI): 3.66-24.3 (4) asphyxia p=0.001 OR= 4.16 CI= 1.75-9.87 (5) consanguineous marriage p=0.001 OR= 3.02 CI= 1.53-5.97 (6) NICU history p=0.003 OR= 2.59 CI= 1.38-4.87 (95% CI). Conclusion: The presented six predictors can be used to determine the medical intractability in children with epilepsy in order to provide early alternative treatment protocols for better seizure control.Item Nutritional interventions improve quality of life of caregivers of children with neurodevelopmental disordersAyca, S; Dogan, G; Sapmaz, SY; Dündar, PE; Kasirga, E; Polat, MIntroduction: Children with neurodevelopmental disorders are at high risk for malnutrition. We aimed to investigate the impact of nutritional interventions to children with neurodevelopmental disorders and the quality of life of caregivers. Materials/Method: This is a prospective interventional study of 91 children with neurodevelopmental disorders. The children were separated into two groups: the intervention group and control group. The intervention group was selected from among children who had not been evaluated for nutrition and feeding problems by a pediatric gastroenterologist or dietician for the past one year. Children in the intervention group were called for follow-up visits and their nutritional intervention and anthropometric measurements were initiated by a pediatric gastroenterologist and dietician, at one month, three months, six months, and one year. The WHOQoL-BREF quality of life scale was completed by the caregivers of the children at baseline and at one year. Results: The intervention group had increased malnutrition (p < 0.001) and gastrointestinal system pathologies such as dysphagia (p < 0.001), constipation (p = 0.02), gastroesophageal reflux (p = 0.03) at baseline. After the nutritional intervention, 77.7% of the intervention group gained weight and 55.5% reached the target weight. The quality of life scale scores at baseline were lower among caregivers of the intervention group; however, they reached those of the control group after the nutritional intervention. Conclusion: Close multidisciplinary nutrition monitoring enables children with neurodevelopmental disorders to thrive appropriately and improves the quality of life of caregivers.Item Hopelessness and factors affecting hopelessness in high school studentsÖzmen, D; Dündar, PE; Çetinkaya, AC; Taskin, O; Özmen, EObjective: The purpose of this study was to determine the level of hopelessness and to examine the effects of socio-demographic features, depression, self-esteem on hopelessness in a high school population. Methods: A cross-sectional survey was conducted among 1185 ninth-grade Turkish adolescents aged between 14 and 19. Hopelessness, sef esteem and depression levels were measured with Beck Hopelessness Scale, the Rosenberg Self-Esteem Scale and Children's Depression Inventory respectively. Student's t-test and analysis of variance were used to examine relationships among the variables. Results: Being male, lower income, lower education levels in parents, perception of family status as low, depression, lower self esteem, perception of quality of life as low were positively correlated with the mean score of Beck Hopelessness Scale. On the other hand only 16.6% of the students responded as 'yes' to item 'my future seems dark to me' and 12.8% of the students responded as 'no' to item 'I look forward to the future with hope and enthusiasm.' Conclusion: The results of this study suggest that school-based adolescents in urban part of Turkey have hope for the future. But the prevalence of hopelessness was not rare in school-based adolescents and it was more common in the children of families with low socio-economical level. Hopelessness may be one of the important indicators of low subjective well-being that should be recognized by the health care personnel.Item The Threshold Value of Anti-HCV Test in the Diagnosis of HCV InfectionEcemis, T; Akçali, S; Dündar, PE; Sanlidag, TObjective: The initial step in the diagnosis of hepatitis C virus (HCV) infection is to screen for anti-HCV antibody, followed by confirmation of positive results with nucleic acid amplification tests. In the recent studies, using reactivity threshold, S/Co (signal to cut-off) ratio greater than 1 has yielded results that are highly consistent with HCV-RNA test. We aimed to determine the most appropriate S/Co level for anti-HCV enzyme immunoassay (ETA) that would predict HCV infection. Material and Methods: We compared the results of 387 patients acquired by Anti-HCV using microparticle ETA and HCV-RNA using hybridization methods. Taking the HCV-RNA test as gold standard for HCV infection, the sensitivity, specificity and predictive values of ETA test were determined and receiver operating characteristic (ROC) analysis was performed to detect the best threshold of reactivity. Results: ETA test showed 197 (49.2%) positive and 190 (50.9%) negative results, and the sensitivity and specificity were calculated as 94.9% and 60.4%, respectively. Positive and negative predictive values were 38.1% and 97.9%, respectively. ROC analysis revealed that the best S/Co level was 5 and, based on this value, sensitivity and specificity were 92.4% and 76.6%, respectively. Computed positive predictive value was 50.3% and negative predictive values was 97.5%. Conclusion: We investigated the best values of reactivity for anti-HCV ETA test and found S/Co >= 5.Item Acute Kidney Injury Incidence According to The RIFLE Criteria and Risk Factors in Critically Ill PatientsKaragoz, P; Kefi, A; Dündar, PE; Canan, S; Çivi, MObjective: In our study, it was aimed to investigate the relationship between RIFLE classification and the risk factors such as acute renal failure incidence, kidney failure in terms of comorbid conditions, critical conditions before and after hospitalization, if any, genetic predispositions, drug use, scores on administration day to the hospital and mortality in intensive care unit patients. Material and Method: A total of 200 patients hospitalized in anesthesiology and reanimation intensive care unit (ICU) between March 1, 2012 and March 31, 2013 were prospectively evaluated. The patients with a history of established chronic renal failure or hemodialysis, under 18 years of age and the patients hospitalized in ICU less than 48 hours were excluded. Data of the patients regarding age, gender, body mass index (BMI), diagnosis at the hospitalization, history of any operation, smoking status, medications, durations of ICU stay and mechanical ventilation, SOFA and APACHE II scores on the 1st day, the worst RIFLE score during the hospitalization, medical status at the end were recorded. The patients whom creatinine levels were not increased significantly and/or GFR and urine output were not decreased were accepted as out of RIFLE. Results: Age, BMI, diagnosis at the hospitalization, smoking status, presence and duration of chronic disease, analgesia, antibiotic and diuretic usages, presences bleeding and hypotension episodes, mechanical ventilation and total ICU hospitalization durations, SOFA and APACHE II scores on the 1st day were found to be significantly related to RIFLE classification. Gender, history and type of operation, type of chronic disease, glucocorticoids, HES, radiocontrast drug administration, renal stone disease, familial renal disease history were not found significantly related. Increased RIFLE scores were found to be related with increased mortality. Conclusion: We concluded that recognizing the factors leading to renal injury/failure and usage of RIFLE classification in daily care of patients are important to decrease mortality and morbidity of ICU patients by increasing the awareness.Item The prevalence of suicide ideation and suicide attempts in Manisa city centreDeveci, A; Taskin, EO; Dündar, PE; Demet, MM; Kaya, E; Özmen, E; Dinç, GObjective: Suicide attempts are a major public health problem. This study aimed to investigate the lifetime prevalence of suicide ideation and suicide attempts in Manisa city centre. Risk factors related to suicide ideations and attempts were also studied. Method: This study was carried out in Manisa city centre. Using cluster and systematic samples, data were collected from 1086 persons 15-65 years old. Separate questions were asked about the lifetime occurrence of suicide ideation (Have you ever seriously thought about committing suicide?), and suicide attempts (Have you ever attempted suicide?). A form for suicide attempters was used to determine the characteristics of the attempts. Results: The lifetime prevalences of suicide ideation and suicide attempts were 6.6% (n=72) and 2.3% (n=25), respectively. Marital problems were the most common stressor in suicide attempts (44%, n=11). Approximately two thirds of the suicide attempters used a drug overdose for suicide. Of all the suicide attempters, 24% (n=6) had made previous attempts. The essential risk factors for suicide ideation were being female (p=0.012), smoking (p=0.001), consuming alcohol (p=0.028), having a previous psychiatric disorder (p < 0.0001), and a family history of psychiatric disorders (p=0.021). The essential risk factors for suicide attempts were smoking (p=0.005), having a previous psychiatric disorder (p < 0.0001), and a family history of psychiatric disorders (p=0.029). Conclusion: The results of the present study suggest that suicide attempts must be carefully evaluated in subjects with previous psychiatric disorders, previous suicide attempts and a family history of psychiatric disorders. It is necessary to know the clinical and demographic features related to suicide attempts.Item Assessment of COVID-19 Contact Healthcare Workers at Manisa Celal Bayar University HospitalDündar, PE; Sen Gündogan, NE; Erten, H; Deniz, G; Özkaya, YIntroduction: In the COVID-19 pandemic process, the health of healthcare workers with a high risk of infection is critical. Many health- care workers have become infected while serving COVID-19 patients, and they have also been and are still exposed to the disease agent at hospital, household or community-based. The aim of this study was to determine the risk status of healthcare workers in contact with COVID-19 patients working at Manisa Celal Bayar University Hospital, and to reveal COVID-19 surveillance and related results. Materials and Methods: This descriptive study was based on examining the data of healthcare workers (HW) that came in contact with the disease between 1 April and 31 December 2020 to the COVID-19 Surveillance Unit (SU), which was established by Manisa Celal Bayar University Public Health Department during the pandemic process. Results: Among the in-contact health workers; 65.7% were females, 42.5% were nurses and 26.0% were physicians. 23.8% of the contacts were high, 42.9% medium and 33.3% low risk. High risk contact percanteges were statistically higher in the emergency unit personal, laboratory workers and household/community based contacts (p= 0.000). PCR positivity rate was 10.1% in high risk con- tact and 3.6% in medium risk contact (p= 0.000). During the research period, the rate of COVID-19 positivity in healthcare workers at Manisa Celal Bayar University Hospital was determined as 21.9% (n= 374). In the study, 24.9% of COVID-19 positive healthcare workers were physicians and 29.0 % were nurses. Conclusion: 23.8% of HCW were evaluated as high risk contact and 21.9% of the group tested positive. High risk contact percanteges were statistically higher in the emergency unit personal, laboratory workers and household/community based contacts. Protecting healthcare workers from infection in the fight against pandemics and performing contact follow-ups are also vital for continuity of service.Item Investigation of the dual cascade algorithm in the diagnosis of antinuclear antibodiesEcemis, T; Farasat, VT; Dugan, Y; Sener, AG; Ece, GT; Dündar, PE; Sanlidag, TBackground: The dual cascade algorithm which involves screening and confirmation of antinuclear antibodies (ANAs) by further reflex testing is widely used in the detection of ANAs. We aimed to investigate this algorithm which is commonly used in many laboratories. Methods: A total of 475 sera obtained from patients with a clinical suspicion of systemic autoimmune rheumatic diseases (SARDs) upon which three expert assessors agreed for interpretation in the indirect immunofluorescence (IIF) test were determined and tested by the line immunoassay (LIA) containing 16 antigens. The results of the tests were statistically compared and evaluated. Results: In 141 of the sera (29.7%), there was an agreement between ANA-IIF(+) and LIA(+) results. The overall agreement rate between the two tests for positivity and negativity only was 85.5% with a Cohen's lc coefficient of 0.69. In 118 of these 141 sera (83.7%), pattern and associated ANA agreement was detected with an overall agreement rate of 80.6% and a Cohen's kappa coefficient of 0.57. The highest agreement between the pattern and associated ANAs was seen in centromere, dense fine speckled (DFS) and cytoplasmic reticular patterns. In these patterns, the rate of anti-centromere-associated protein B (CENP-B), anti-DFS and anti-antimitochondrial antibody M2 (anti-AMA-M2) antibodies were 93.4%, 92.3% and 66.7%, respectively. Conclusions: We found an overall moderate agreement between IIF screening and LIA confirmation tests. However, the level of agreement varies according to the pattern type. The discrepancy in agreement rates may cause false reflex test requests. Our results highlight the need for collaboration between clinical and laboratory professionals in selected cases instead of the reflex testing approach.Item A Multicenter Analysis of Subjectivity of Indirect Immunofluorescence Test in Antinuclear Antibody ScreeningFarasat, VT; Ecemis, T; Dogan, Y; Sener, AG; Ece, GT; Dündar, PE; Sanlidag, TObjectives: This study aims to evaluate the interpretation of the antinuclear antibody (ANA)-indirect immunofluorescence (IIF) test results based on the interpreter-related subjectivity and to examine the inter-center agreement rates with the performance of each laboratory. Patients and methods: The ANA-IIF testing was carried out in a total of 600 sera and evaluated by four laboratories. The inter-center agreement rates were detected. The same results given by the four centers were accepted as gold standard and the predictive values of each center were calculated. Results: The inter-center agreement was reported for ANA-IIF test results from 392 of 600 (65.3%) sera, while 154 of 392 results were positive. Four study centers reported 213 (35.5%), 222 (37.0%), 266 (44.3%), and 361 (60.2%) positive test results, respectively. In terms of the patterns, the highest and lowest positive predictive values were 72.3% and 42.7%, respectively, while the highest and lowest negative predictive values were 99.6% and 61.5%, respectively. The agreement for semi-quantitative evaluation at three levels of fluorescence intensity stated by four centers was detected in 100 sera at 87% 3(+), while the other two levels were 6% and 7%. The highest predictive value for the highest fluorescence intensity of 3(+) was found to be 71.9%. Conclusion: Significant differences may be observed among laboratories in terms of qualitative results, patterns, and semi-quantitative determination of the fluorescence intensity in the ANA-IIF testing, particularly at low fluorescence intensity levels and in those with speckled patterns. In case of any discrepancy between ANA-IIF test and clinical prediagnosis, the test should be repeated in another laboratory, if necessary.Item QUALITY OF LIFE OF WORKERS AGED 14-16 YEARS IN THE MANISA APPRENTICE TRAINING CENTERDündar, PE; Baydur, H; Eser, E; Bilge, B; Nesanir, N; Pala, T; Ergör, A; Oral, AObjective: The literature related to child labor, discusses the causes and socioeconomic factors contributing to child labor but very few studies examine the quality of life among child workers. The purpose of this cross-sectional study was to investigate the quality of life (QoL), socioeconomic and labor related factors in young people aged 14-16 in the city of Manisa. Methods: The study population consisted of 266 students who were attending the Apprentice Training Center in Manisa. The QoL of the subjects was measured by the adolescent version of KINDL-R (Kiddo-Kindl). Odds ratios (95% Confidence Interval) were used in the assessment. Logistic regression analysis was performed in multivariate analysis. Results: Of the 253 adolescent workers, 77.9% were male, with a mean age of 15.6(0.5). According to logistic regression analysis; being female (OR=2.9), lack of family health insurance (OR=2.3), being exposed to family violence (OR=3.7) and absenteeism (OR=2.4) were associated with total Qol. Lack of family health insurance, insufficiency in family income, using alcohol, being exposed to family violence, job dissatisfaction and father illiteracy were associated with poorer QoL of six domains of KINDL-R. Conclusion: The findings of this study concludes that, socioeconomic, family and job related variables are factors associated with QoL in adolescent workers.