Browsing by Author "Delen L.A."

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    Peripheral blood smear findings of COVID-19 patients provide İnformation about the severity of the disease and the duration of hospital stay
    (Universita Cattolica del Sacro Cuore, 2021) Berber I.; Cagasar O.; Sarici A.; Berber N.K.; Aydogdu I.; Ulutas O.; Yildirim A.; Bag H.G.G.; Delen L.A.
    Background: Data about the morphological changes in peripheral blood smears during COVID-19 infection and their clinical severity association are limited. We aimed to examine the characteristics of the cells detected in the pathological rate and/or appearance and whether these findings are related to the clinical course by evaluating the peripheral blood smear at the time of diagnosis in COVID-19 patients. Methods: Clinical features, laboratory data, peripheral blood smear of fifty patients diagnosed with COVID-19 by PCR was evaluated at diagnosis. Peripheral smear samples of the patients were compared with the age and sex-matched 30 healthy controls. Pictures were taken from the patient's peripheral blood smear. Patients were divided into two groups. Mild and severe stage patient groups were compared in terms of laboratory data and peripheral smear findings. The relationship between the laboratory values of all patients and the duration of hospitalization was analyzed. Results: The number of segmented neutrophils and eosinophils were low, pseudo-Pelger-Huet, pseudo-Pelger-Huet/mature lymphocyte ratio, atypical lymphocytes, monocytes with vacuoles, bands, and pyknotic neutrophils rates were higher in the peripheral blood smear of the patient group (p <0.05). Increased pseudo-Pelger-Huet anomaly, pseudo-Pelger Huet/mature lymphocyte ratio, a decreased number of mature lymphocytes, and eosinophils in peripheral blood smear were observed in the severe stage patients (p <0.05). A negative correlation was observed between hospitalization duration and mature lymphocyte and monocytes with vacuoles rates (p <0.05). Conclusion: A peripheral blood smear is an inexpensive, easily performed, and rapid test. Increased Pseudo-Pelger-Huet anomaly/mature lymphocyte rate suggests a severe stage disease, while high initial mature lymphocyte and monocytes with vacuoles rates at the time of diagnosis may be an indicator of shortened duration of hospitalization. © 2021 Universita Cattolica del Sacro Cuore. All rights reserved.
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    A view on pediatric airway management: a cross sectional survey study
    (Edizioni Minerva Medica, 2022) Saracoglu A.; Saracoglu K.T.; Sorbello M.; Kurdi R.; Greif R.; Abitagaoglu S.; Akin M.; Aksu A.; Aladag E.; Alagoz A.; Alanoglu Z.; Alicikus Tuncel Z.; Altinisik H.B.; Ambrosoli A.L.; Amella S.; Andrašovský A.; Andreotti A.; Arici A.G.; Armstrong J.; Arslan B.; Ávila E.; Aydogmus I.; Ayhan A.; Ayoglu H.; Ayvat P.; Bakis M.; Basaran B.; Baytar C.; Begec Z.; Belete A.; Belludi R.; Bianco M.C.; Bilgin M.U.; Biricik E.; Brueggeney M.K.; Bunjaku D.; Buyukkocak U.; Catineau J.; Cebrián C.G.; Chinnappa S.M.; Cicekci A.; Corte-Ballester J.; Cuéllar Martínez A.B.; Caglar T.; Calisir F.; Cokay Abut Y.; Delen L.A.; Deligoz O.; Demirgan S.; Distefano R.; Dmytriiev D.; Duarte L.; Ece C.; El-Tahan M.; El-Hatib M.; Erdogan Ari D.; Erkalp K.; Erol D.; Erturk E.; Frada R.; Fuchs A.; Garini E.; Gecici M.E.; Giallongo M.; Gomes C.; Gurbuz H.; Has Selmi N.; Hasani A.; Hernandez Cera C.; Hilker T.; Horatanaruang D.; Huitink J.; Karaaslan P.; Karaveli A.; Karisik M.; Kavas A.D.; Kaya A.; Kendigelen P.; Kilinc G.; Koc S.; Dilmen O.; Kozanhan B.; Kupeli I.; Kuyrukluyildiz U.; Lleshi A.; Loizou M.; Luanpholcharoenchai J.; Martinez V.; Matoshi D.; Maurya I.; Meco B.C.; Michalek P.; Milic M.; Mitre I.; Montealegre F.; Nair A.; Nallbani R.; Ng A.; Oc B.; Ok G.; Olguner C.; Ozkan D.; Oksuz G.; Ozcan M.S.; Ozden E.S.; Ozden Omaygenc D.; Ozer Y.; Ozmenoglu Turker H.; Ozmert S.; Rai E.; Rangappa D.; Roca De Togores A.; Salgado H.; Santos P.; Sari S.; Saritas A.; Saygi Emir N.; Sen B.; Shallik N.; Shamim F.; Shirgoska B.; Silay E.; Sinha T.; Srimueang T.; Sudarshan P.; Sugur T.; Sumer I.; Szucs Z.; Sahin T.; Sanal Bas S.; Tan J.; Tawfik L.; Topal S.; Toy E.; Turan Civraz A.Z.; Unal D.; Ural S.G.; Ustalar Ozgen S.Z.; Uysal H.; Yesildal H.; Yilmaz C.; Yuen V.; Yurt E.; Yuzkat N.; Zdravkovic M.; Isohanni M.
    BACKGROUND: This survey aimed to investigate routine practices and approaches of clinicians on pediatric airway in anesthesia and intensive care medicine. METHODS: A 20-question multiple-choice questionnaire with the possibility to provide open text answers was developed and sent. The survey was sent to the members of European Airway Management Society via a web-based platform. Responses were analyzed thematically. Only the answers from one representative of the pediatric service of each hospital was included into the analysis. RESULTS: Among the members, 143 physicians responded the survey, being anesthesiologists (83.2%), intensivists (11.9%), emergency medicine physicians (2.1%), and (2.8%) pain medicine practitioners. Astraight blade was preferred by 115 participants (80.4%) in newborns, whereas in infants 86 (60.1%) indicated a curved blade and 55 (38.5%) a straight blade. Uncuffed tracheal tube were preferred by 115 participants (80.4%) in newborns, whereas 24 (16.8%) used cuffed tubes. Approximately 2/3 of the participants (89, 62.2%) reported not to use routinely a cuff manometer in their clinical practice, whereas 54 participants (37.8%) use it routinely in pediatric patients. Direct laryngoscopy for routine pediatric tracheal intubation was reported by 127 participants (88.8%), while 16 (11.2%) reported using videolaryngoscopes routinely. Interestingly, 39 (27.3%) had never performed neither videolaryngoscopy nor flexible bronchoscopy in children. These results were significantly less in hospitals with a dedicated pediatric anesthesiologist. CONCLUSIONS: This survey on airway management in pediatric anesthesia revealed that the use of cuffed tubes and the routine monitoring of cuff pressure are rare. In addition, the rate of videolaryngoscopy or flexible optical intubation was low for expected difficult intubation. Our survey highlights the need for properly trained pediatric anesthesiologists working in-line with updated scientific evidence. © 2022 Edizioni Minerva Medica. All rights reserved.