Browsing by Author "Demir, O"

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    Association between severity of LUTS, erectile dysfunction and components of metabolic syndrome
    Demir, O; Akgul, K; Akar, Z; Cakmak, O; Ozdemir, I; Bolukbasi, A; Can, E; Gumus, B
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    Patient and partner satisfaction in penile prosthesis implantation
    Gumus, B; Sabin, A; Cakmak, O; Demir, O; Can, E; Celen, I; Bolukasi, A; Esen, A
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    Association between premature ejaculation and LUTS severity
    Demir, O; Akgiil, K; Akar, Z; Cakmak, O; Ozdemir, I; Bolukbasi, A; Can, E; Gumus, B
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    Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome
    Demir, O; Akgul, K; Akar, Z; Cakmak, O; Ozdemir, I; Bolukbasi, A; Can, E; Gumus, BH
    Introduction. The purpose of this study was to investigate the association between severity of lower urinary tract symptoms (LUTS), erectile dysfunction (ED) and metabolic syndrome. Methods. Our study population included a consecutive series of 190 patients with LUTS (International Prostate Symptom Score-IPSS 7) with or without manifestations of the metabolic syndrome. The diagnoses of diabetes mellitus and hypertension were obtained from the patient's medical history. Data on blood pressure, waist measure, body height and weight were collected and body mass index were calculated. Patients were assessed based on the International Index of Erectile Function (IIEF) for ED and IPSS and IPSS-Quality of Life for LUTS. Blood samples were drawn from fasting patients to determine, fasting blood glucose (FBG), triglycerides, HDL-cholesterol and serum total testosterone levels. Results. In severe LUTS patient group, IIEF erectile function domain scores were significantly lower than moderate LUTS patient group (p0.05). Multiple logistic regression analysis confirmed that presence of ED was the most predictor of severe LUTS. The prevalence of metabolic syndrome was higher in patients with severe LUTS (26%vs. 46%, p=0.009). The severe form of the LUTS was significantly correlated with waist circumference 102cm (p0.05), blood pressure 130/85mmHg (p0.05) and FBG 110mg/dl (p0.01). Conclusion. Obesity, high plasma level of FBG and hypertension constitute risk factors for the development of severe LUTS. Metabolic syndrome may play a key role in the pathogenesis in both ED and LUTS. Presence of ED is the most predictor of severe LUTS.
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    Nation-wide analysis of the impact of Covid-19 pandemic on daily urology practice in Turkey
    Bozkurt, O; Sen, V; Irer, B; Sagnak, L; Onal, B; Tanidir, Y; Karabay, E; Kaya, C; Ceyhan, E; Baser, A; Duran, MB; Suer, E; Celen, I; Selvi, I; Ucer, O; Karakoc, S; Sarikaya, E; Ozden, E; Deger, D; Egriboyun, S; Ongun, S; Gurboga, O; Asutay, MK; Kazaz, IO; Yilmaz, IO; Kisa, E; Demirkiran, ED; Horsanali, O; Akarken, I; Kizer, O; Eren, H; Ucar, M; Cebeci, OO; Kizilay, F; Comez, K; Mercimek, MN; Ozkent, MS; Izol, V; Gudeloglu, A; Ozturk, B; Akbaba, KT; Polat, S; Gucuk, A; Ziyan, A; Selcuk, B; Akdeniz, F; Turgut, H; Sabuncu, K; Kaygisiz, O; Ersahin, V; Kahraman, HI; Guzelsoy, M; Demir, O
    Objective To present a nation-wide analysis of the workload of urology departments in Turkey week-by-week during Covid-19 pandemic. Methodology The centres participating in the study were divided into three groups as tertiary referral centres, state hospitals and private practice hospitals. The number of outpatients, inpatients, daily interventions and urological surgeries were recorded prospectively between 9-March-2020 and 31-May-2020. All these variables were recorded for the same time interval of 2019 as well. The weekly change of the workload of urology during pandemic period was evaluated, also the workload of urology and the distributions of certain urological surgeries were compared between the pandemic period and the same time interval of the year 2019. Results A total of 51 centres participated in the study. The number of outpatients, inpatients, urological surgeries and daily interventions were found to be dramatically decreased by the 3rd week of pandemics in state hospitals and tertiary referral centres; however, the daily urological practice were similar in private practice hospitals throughout the pandemic period. When the workload of urology in pandemic period and the same time interval of the year 2019 were compared, a huge decrease was observed in all variables during pandemic period. However, temporary measures like ureteral stenting, nephrostomy placement and percutaneous cystostomy have been found to increase during Covid-19 pandemic compared with normal life. Conclusions Covid-19 pandemic significantly affected the routine daily urological practice likewise other subspecialties and priority was given to emergent and non-deferrable surgeries by urologists in concordance with published clinical guidelines.
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    Cutaneous findings in patients with acromegaly and its relationship with concomitant endocrinopathies
    An, IS; Kahraman, FC; Bilgic, A; Aktürk, AS; Albayrak, H; Kartal, D; Cinar, SL; Solak, SS; Uslu, M; Sanli, HE; Yildizhan, IK; Sahin, MT; Zindanci, I; Savas, S; Ayhan, E; Cinel, M; Atas, ENS; Aydemir, M; Selek, A; Elbueken, G; Zuhur, SS; Karaca, Z; Bülbül, BY; Ünübol, M; Demir, O; Hekimsoy, Z; Tuna, M; Asilsoy, M; Çetin, S
    ObjectivesSkin changes in acromegaly are often the first sign of the disease. The aim of this study was to describe the cutaneous findings in patients with acromegaly. In addition, a secondary aim was to investigate the possible association of these findings with remission status and concomitant endocrinopathies.Design, Patients, and MeasurementsIn this prospective multicenter study, 278 patients over the age of 18 years with acromegaly who were followed up in 14 different tertiary healthcare institutions were included. These patients, who were followed up by the Endocrinology Department, were then referred to a dermatologist for dermatological examination. The frequency of skin lesions was investigated by detailed dermatologic examination. Dermatological diagnosis is reached by clinical, dermatological and/or dermoscopic examination, and rarely skin punch biopsy examinations in suspicious cases. The possible association of the skin findings between remitted and nonremitted patients and with concomitant endocrinopathies were evaluated.ResultsThe most common skin findings in patients with acromegaly in our study were skin tags (52.5%), cherry angiomas (47.4%), seborrhoea (37%), varicose veins (33%), acneiform lesions (28.8%), hyperhidrosis (26.9%) and hypertrichosis (18.3%). Hypertrichosis was significantly more prevalent in patients nonremitted (p: .001), while xerosis cutis was significantly more prevalent in patients remitted (p: .001). The frequency of diabetes mellitus and hypothyroidism was significantly higher in patients with varicose veins and seborrhoeic keratosis than those without. Additionally, the coexistence of hypothyroidism, hyperthyroidism and galactorrhea was significantly higher in patients with Cherry angioma than in those without Cherry angioma (p-values: .024, .034 and .027, respectively). The frequency of hypogonadism in those with xerosis cutis was significantly higher than in those without (p: .035).ConclusionsCutaneous androgenization findings such as skin tag, seborrhoea, acne and acanthosis nigricans are common in patients with acromegaly. Clinicians should be aware that skin findings associated with insulin resistance may develop in these patients. It can be said that the remission state in acromegaly has no curative effect on cutaneous findings. Only patients in remission were less likely to have hypertrichosis. This may allow earlier review of the follow-up and treatment of acromegaly patients presenting with complaints of hypertrichosis. Additionally, it can be said that patients with skin findings such as cherry angioma may be predisposed to a second endocrinopathy, especially hypothyroidism. Including dermatology in a multidisciplinary perspective in acromegaly patient management would be beneficial to detect cutaneous findings earlier.
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    THE DEMOGRAPHY AND PARTNER'S RELATIONSHIP OF PREMATURE EJACULATION IN TURKEY: MULTICENTER STUDY
    Can, E; Demir, O; Gumus, B; Degirmenci, T; Bolukbasi, A; Basar, M; Akbal, C; Guner, GK; Alici, B; Inci, K; Aridogan, A; Erol, H; Akdeniz, F; Zeren, F; Esen, AA
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    Erectile function and late-onset hypogonadism symptoms related to lower urinary tract symptom severity in elderly men
    Bozkurt, O; Bolat, D; Demir, O; Ucer, O; Sahin, A; Ozcift, B; Pektas, A; Turan, T; Gümüs, BH; Can, E; Bolukbasi, A; Erol, H; Esen, A
    The aim of this study was to evaluate the relationship between lower urinary tract symptoms (LUTSs), erectile dysfunction (ED) and symptomatic late-onset hypogonadism (SLOH) in ageing men in the Aegean region of Turkey. Five hundred consecutive patients >40 years old who had been in a steady sexual relationship for the past 6 months and were admitted to one of six urology clinics were included in the study. Serum prostate-specific antigen and testosterone levels and urinary flow rates were measured. All patients filled out the International Prostate Symptom Score and Quality of Life (IPSS-QoL), International Index of Erectile Function (IIEF) and Aging Males' Symptoms (AMS) scale forms. Of the patients, 23.9% had mild LUTSs, 53.3% had moderate LUTSs and 22.8% had severe LUTSs. The total testosterone level did not differ between groups. Additionally, 69.6% had ED. The presence of impotence increased with increasing LUTS severity. Symptomatic late-onset hypogonadism (AMS>27) was observed in 71.2% of the patients. The prevalence of severe hypogonadism symptoms increased with the IPSS scores. A correlation analysis revealed that all three questionnaire scores were significantly correlated. In conclusion, LUTS severity is an age-independent risk factor for ED and SLOH. LUTS severity and SLOH symptoms appear to have a strong link that requires etiological and biological clarification in future studies.
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    THE APPLICABILITY OF A PREMATURE EJACULATION PROFILE QUESTIONNAIRE FORMS IN OUR COUNTRY
    Can, E; Demir, O; Gumus, B; Degirmenci, T; Bolukbasi, A; Basar, M; Akbal, C; Ozgur, GK; Alici, B; Inci, K; Aridogan, A; Erol, H; Akdeniz, F; Zeren, F; Esen, AA
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    The effect of SWL and URS on health-related quality of life in proximal ureteral stones
    Ceylan, Y; Ucer, O; Bozkurt, O; Gunlusoy, B; Mertoglu, O; Zumrutbas, AE; Yildiz, G; Irer, B; Muezzinoglu, T; Demir, O
    Objectives: We aimed to compare the effect of shock wave lithotripsy (SWL) and ureteroscopic lithotripsy (URS) on health-related quality of life (HRQoL) for the treatment of proximal ureteral stones. Material and methods: Between April 2014 and July 2015, patients with proximal ureteral stones who were successfully treated with URS or SWL in seven different centers were included. Patients were divided into two groups according to stone size: stones <= 10 mm and >10mm. HRQoL subscales which were evaluated by the Medical Outcome Study Short-Form 36-item survey (SF-36) Turkish version were compared for URS and SWL in these two groups one month after the performed procedure. Results: A total of 273 patients were included in the study. While 116 (52.5%) patients were treated with ureteroscopic lithotripsy, SWL was used for 105 (47.5%) patients. Fifty-two patients were excluded from the study. In proximal ureteral stones <= 10 mm, there were no statistically significant differences for any of the eight subscales of the SF-36 questionnaire. Regarding stones >10mm, it was found that the three subscales of the SF-36 questionnaire - role limitations because of physical health problems (RP), bodily pain (BP), and general health perception (GH) - were significantly lower in the SWL group compared with the URS group. Conclusions: Patients with proximal ureteral stones >10mm who were treated with URS generally may have a more favorable HRQoL than those treated with SWL in short-term follow-up.