Browsing by Author "Demir G."

Now showing 1 - 5 of 5
  • No Thumbnail Available
    Item
    The clinical and pathological features of 133 colorectal cancer patients with brain metastasis: a multicenter retrospective analysis of the Gastrointestinal Tumors Working Committee of the Turkish Oncology Group (TOG)
    (Humana Press Inc., 2014) Tanriverdi O.; Kaytan-Saglam E.; Ulger S.; Bayoglu I.V.; Turker I.; Ozturk-Topcu T.; Cokmert S.; Turhal S.; Oktay E.; Karabulut B.; Kilic D.; Kucukzeybek Y.; Oksuzoglu B.; Meydan N.; Kaya V.; Akman T.; Ibis K.; Saynak M.; Sen C.A.; Uysal-Sonmez O.; Pilancı K.N.; Demir G.; Saglam S.; Kocar M.; Menekse S.; Goksel G.; Yapar-Taskoylu B.; Yaren A.; Uyeturk U.; Avci N.; Denizli B.; Ilis-Temiz E.
    Brain metastasis in colorectal cancer is highly rare. In the present study, we aimed to determine the frequency of brain metastasis in colorectal cancer patients and to establish prognostic characteristics of colorectal cancer patients with brain metastasis. In this cross-sectional study, the medical files of colorectal cancer patients with brain metastases who were definitely diagnosed by histopathologically were retrospectively reviewed. Brain metastasis was detected in 2.7 % (n = 133) of 4,864 colorectal cancer patients. The majority of cases were male (53 %), older than 65 years (59 %), with rectum cancer (56 %), a poorly differentiated tumor (70 %); had adenocarcinoma histology (97 %), and metachronous metastasis (86 %); received chemotherapy at least once for metastatic disease before brain metastasis developed (72 %), had progression with lung metastasis before (51 %), and 26 % (n = 31) of patients with extracranial disease at time the diagnosis of brain metastasis had both lung and bone metastases. The mean follow-up duration was 51 months (range 5–92), and the mean survival was 25.8 months (95 % CI 20.4–29.3). Overall survival rates were 81 % in the first year, 42.3 % in the third year, and 15.7 % in the fifth year. In multiple variable analysis, the most important independent risk factor for overall survival was determined as the presence of lung metastasis (HR 1.43, 95 % CI 1.27–4.14; P = 0.012). Brain metastasis develops late in the period of colorectal cancer and prognosis in these patients is poor. However, early screening of brain metastases in patients with lung metastasis may improve survival outcomes with new treatment modalities. © 2014, Springer Science+Business Media New York.
  • No Thumbnail Available
    Item
    Possible complications of martial arts technique
    (BMJ Publishing Group, 2019) Gokalp G.; Berksoy E.; Bardak S.; Demir S.; Demir G.; Bicilioglu Y.; Zengin N.
    [No abstract available]
  • No Thumbnail Available
    Item
    The effect of diabetes camp on glycemic variability in children and adolescents with type 1 diabetes mellitus
    (Galenos Publishing House, 2021) Ata A.; Arı G.; Işıklar H.; Demir G.; Altınok Y.A.; Ersoy B.; Özen S.; Darcan Ş.; Gökşen D.
    Aim: Glycemic variability can be affected in diabetes camps as a result of sports, social activities and nutrition. Close glucose monitoring is necessary to reduce glycemic variability, especially hypoglycemia. The aim assessment of glycemic variability and time in range by use of the flash glucose monitoring system (FGMS) in children and adolescents with type 1 diabetes. Materials and Methods: Thirty-three children and adolescents between 10-18 years of age who participated in the 2018 diabetes camp of Ege University were included. Their glycemic variability indexes were recorded. Results: The mean age and duration of diabetes mellitus in the study group was 13.3±0.5 and 4.9±0.7 years respectively. Twelve (43%) of the participants were boys and 16 (57%) were girls. Ten (35.7%) of the participants used continuous subcutaneous insulin infusion (CSII) pump therapy while 18 (64.3%) used multiple dose insulin therapy. When the participants were evaluated according to time in range (TIR), the duration of TIR increased, and level 1 and level 2 hyperglycemia decreased during the camp. Participants using CSII had spent more time in level 2 hypoglycemia before camp, but during and after the camp, similar values were reached for both groups. Before the camp, participants with good metabolic control had a longer duration of hypoglycemia than those participants with poor metabolic control. During and after the camp, level 1 and level 2 hypoglycemia periods were similar between the two groups. Conclusion: In diabetes camp, healthy diet, regular exercise, and close glycemic control improve glycemic variability. By using FGMS, normoglycemia periods can be increased without increasing hypoglycemic attacks. As a result, using FGMS had a positive effect on diabetes management and the control of hypoglycemia periods during the diabetes camp. © Copyright 2021 by Ege University Faculty of Medicine, Department of Pediatrics and Ege Children’s Foundation The Journal of Pediatric Research, published by Galenos Publishing House.
  • No Thumbnail Available
    Item
    State-based measurement of emotion regulation: The Turkish versions of SERI and S-DERS
    (Springer, 2023) Gökdağ C.; Günay G.; Demir G.
    Recent studies emphasize the importance of state-based measurement of emotion regulation because of its context-sensitive and flexible background. In many studies, emotion regulation is measured as state-based as well as trait-based; however, only a few offers standard measurements. The State Emotion Regulation Inventory (SERI) and the State-Difficulties in Emotion Regulation (S-DERS) are standardized scales specifically designed for this purpose. Ultimately, the aim of this study was to adapt these scales into Turkish and investigate their psychometric properties using a laboratory-based emotion induction procedure. The data were collected from 167 undergraduate students. They first filled out trait-based scales, were then recruited to the stage of negative emotional state induction, and, finally, responded to the question in the SERI and the S-DERS to evaluate their emotion regulation experiences during the emotion induction phase. As a result, we confirmed the four-factor structures of the scales with good internal consistencies. While the SERI had weak associations with emotion dysregulation, thought control, and psychological distress, the S-DERS had strong relationships with these variables. Moreover, the incremental validities of the SERI and the S-DERS were acceptable when predicting both negative emotional state and psychological distress. Overall, our results suggest that the SERI and S-DERS are psychometrically valid and reliable measurements to assess state emotion regulation in Turkish speakers. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
  • No Thumbnail Available
    Item
    Knowledge, Homophobic Attitudes and Behaviors of Medical Students Towards LGBTI+ Individuals: Descriptive Study; [Tıp Fakültesi Öğrencilerinin LGBTİ+ Bireyler ile İlgili Bilgi, Homofobik Tutum ve Davranışları: Tanımlayıcı Çalışma]
    (Turkiye Klinikleri, 2024) Bilgin Şahin B.; Akman D.; Cengiz Özyurt B.; Toraman U.C.; Aktan G.; Cidani B.; Güneş D.; Demir G.; Özen G.; Sergin F.; Tokmak A.A.; Aktay F.
    Objective: The aim of this study is to evaluate the knowledge, behavior, and homophobic attitudes of students in the fourth, fifth and sixth years of the Faculty of Medicine towards LGBTI+ individuals. Material and Methods: The population of the research consists of 607 people who are fourth, fifth and sixth year students at Manisa Celal Bayar University Faculty of Medicine. No sample was selected in the research, and it was aimed to reach the entire population. The participation rate was 46.8% (n=284). The data for the study were collected through an online questionnaire. The questionnaire included questions about sociodemographic characteristics, knowledge, attitude, and behavior towards LGBTI+ individuals, and the Hudson Rickkets Homophobia scale. Results: The research group had an average age of 23.4±1.1 years, with 54.9% women and 45.1% men. Concerning sexual orientation, 90.1% of the group identified as heterosexual, 4.6% as, lesbian/gay and 4.2% as bisexual. The average score of the students on the Hudson and Ricketts Homophobia Scale was 65.14±27.87. There was no significant difference in the mean scores between classes (p>0.05). Students who live in extended families, identify as male, lack LGBTI+ individuals in their close circle, are uninformed about LGBTI+ individuals and their rights, and believe that sexual orientation is a choice and being LGBTI+ is a condition requiring treatment exhibit higher levels of homophobia. Seventy-one point one percent (71.1%) of the students think that the level of knowledge of healthcare professionals about LGBTI+ individuals is insufficient, while 70.1% think that lessons for LGBTI+ individuals are necessary. Additionally, 35.6% of the students believe that being an LGBTI+ individual will affect the healthcare they receive, and 70.1% think that LGBTI+ individuals cannot access comprehensive health services. Conclusion: Only 4.3% of the students think that healthcare professionals' knowledge about LGBTI+ individuals is sufficient, and 70.1% think that lessons for LGBTI+ individuals are necessary. The level of homophobia assessed by the Hudson and Ricketts Homophobia Scale was found to be lower than the results of similar studies across the country. It may be beneficial to integrate awareness-raising trainings in clinical branches into the faculty of Medical school education curriculum. © 2024 by Türkiye Klinikleri.