Browsing by Author "Denburg, J"

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    Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)
    (WILEY) Bousquet, J; Khaltaev, N; Cruz, AA; Denburg, J; Fokkens, WJ; Togias, A; Zuberbier, T; Baena-Cagnani, CE; Canonica, GW; van Weel, C; Agache, I; Aït-Khaled, N; Bachert, C; Blaiss, MS; Bonini, S; Boulet, LP; Bousquet, PJ; Camargos, P; Carlsen, KH; Chen, Y; Custovic, A; Dahl, R; Demoly, P; Douagui, H; Durham, SR; van Wijk, RG; Kalayci, O; Kaliner, MA; Kim, YY; Kowalski, ML; Kuna, P; Le, LTT; Lemiere, C; Li, J; Lockey, RF; Mavale-Manuel, S; Meltzer, EO; Mohammad, Y; Mullol, J; Naclerio, R; Hehir, REO; Ohta, K; Ouedraogo, S; Palkonen, S; Papadopoulos, N; Passalacqua, G; Pawankar, R; Popov, TA; Rabe, KF; Rosado-Pinto, J; Scadding, GK; Simons, FER; Toskala, E; Valovirta, E; van Cauwenberge, P; Wang, DY; Wickman, M; Yawn, BP; Yorgancioglu, A; Yusuf, OM; Zar, H; Annesi-Maesano, I; Bateman, ED; Ben Kheder, A; Boakye, DA; Bouchard, J; Burney, P; Busse, WW; Chan-Yeung, M; Chavannes, NH; Chuchalin, A; Dolen, WK; Emuzyte, R; Grouse, L; Humbert, M; Jackson, C; Johnston, SL; Keith, PK; Kemp, JP; Klossek, JM; Larenas-Linnemann, D; Lipworth, B; Malo, JL; Marshall, GD; Naspitz, C; Nekam, K; Niggemann, B; Nizankowska-Mogilnicka, E; Okamoto, Y; Orru, MP; Potter, P; Price, D; Stoloff, SW; Vandenplas, O; Viegi, G; Williams, D
    Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 million patients from all countries, all ethnic groups and of all ages suffer from allergic rhinitis. It affects social life, sleep, school and work and its economic impact is substantial. Risk factors for allergic rhinitis are well identified. Indoor and outdoor allergens as well as occupational agents cause rhinitis and other allergic diseases. The role of indoor and outdoor pollution is probably very important, but has yet to be fully understood both for the occurrence of the disease and its manifestations. In 1999, during the Allergic Rhinitis and its Impact on Asthma (ARIA) WHO workshop, the expert panel proposed a new classification for allergic rhinitis which was subdivided into 'intermittent' or 'persistent' disease. This classification is now validated. The diagnosis of allergic rhinitis is often quite easy, but in some cases it may cause problems and many patients are still under-diagnosed, often because they do not perceive the symptoms of rhinitis as a disease impairing their social life, school and work. The management of allergic rhinitis is well established and the ARIA expert panel based its recommendations on evidence using an extensive review of the literature available up to December 1999. The statements of evidence for the development of these guidelines followed WHO rules and were based on those of Shekelle et al. A large number of papers have been published since 2000 and are extensively reviewed in the 2008 Update using the same evidence-based system. Recommendations for the management of allergic rhinitis are similar in both the ARIA workshop report and the 2008 Update. In the future, the GRADE approach will be used, but is not yet available. Another important aspect of the ARIA guidelines was to consider co-morbidities. Both allergic rhinitis and asthma are systemic inflammatory conditions and often co-exist in the same patients. In the 2008 Update, these links have been confirmed. The ARIA document is not intended to be a standard-of-care document for individual countries. It is provided as a basis for physicians, health care professionals and organizations involved in the treatment of allergic rhinitis and asthma in various countries to facilitate the development of relevant local standard-of-care documents for patients.
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    Development and implementation of guidelines in allergic rhinitis - an ARIA-GA2LEN paper
    (WILEY) Bousquet, J; Schunemann, HJ; Zuberbier, T; Bachert, C; Baena-Cagnani, CE; Bousquet, PJ; Brozek, J; Canonica, GW; Casale, TB; Demoly, P; Gerth van Wijk, R; Ohta, K; Bateman, ED; Calderon, M; Cruz, AA; Dolen, WK; Haughney, J; Lockey, RF; Lotvall, J; O'Byrne, P; Spranger, O; Togias, A; Bonini, S; Boulet, LP; Camargos, P; Carlsen, KH; Chavannes, NH; Delgado, L; Durham, SR; Fokkens, WJ; Fonseca, J; Haahtela, T; Kalayci, O; Kowalski, ML; Larenas-Linnemann, D; Li, J; Mohammad, Y; Mullol, J; Naclerio, R; O'Hehir, RE; Papadopoulos, N; Passalacqua, G; Rabe, KF; Pawankar, R; Ryan, D; Samolinski, B; Simons, FER; Valovirta, E; Yorgancioglu, A; Yusuf, OM; Agache, I; Ait-Khaled, N; Annesi-Maesano, I; Beghe, B; Ben Kheder, A; Blaiss, MS; Boakye, DA; Bouchard, J; Burney, PG; Busse, WW; Chan-Yeung, M; Chen, Y; Chuchalin, AG; Costa, DJ; Custovic, A; Dahl, R; Denburg, J; Douagui, H; Emuzyte, R; Grouse, L; Humbert, M; Jackson, C; Johnston, SL; Kaliner, MA; Keith, PK; Kim, YY; Klossek, JM; Kuna, P; Le, LT; Lemiere, C; Lipworth, B; Mahboub, B; Malo, JL; Marshall, GD; Mavale-Manuel, S; Meltzer, EO; Morais-Almeida, M; Motala, C; Naspitz, C; Nekam, K; Niggemann, B; Nizankowska-Mogilnicka, E; Okamoto, Y; Orru, MP; Ouedraogo, S; Palkonen, S; Popov, TA; Price, D; Rosado-Pinto, J; Scadding, GK; Sooronbaev, TM; Stoloff, SW; Toskala, E; van Cauwenberge, P; Vandenplas, O; van Weel, C; Viegi, G; Virchow, JC; Wang, DY; Wickman, M; Williams, D; Yawn, BP; Zar, HJ; Zernotti, M; Zhong, N
    P>The links between asthma and rhinitis are well characterized. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines stress the importance of these links and provide guidance for their prevention and treatment. Despite effective treatments being available, too few patients receive appropriate medical care for both diseases. Most patients with rhinitis and asthma consult primary care physicians and therefore these physicians are encouraged to understand and use ARIA guidelines. Patients should also be informed about these guidelines to raise their awareness of optimal care and increase control of the two related diseases. To apply these guidelines, clinicians and patients need to understand how and why the recommendations were made. The goal of the ARIA guidelines is to provide recommendations about the best management options for most patients in most situations. These recommendations should be based on the best available evidence. Making recommendations requires the assessment of the quality of available evidence, deciding on the balance between benefits and downsides, consideration of patients' values and preferences, and, if applicable, resource implications. Guidelines must be updated as new management options become available or important new evidence emerges. Transparent reporting of guidelines facilitates understanding and acceptance, but implementation strategies need to be improved.
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    Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study
    (WILEY) Menditto, E; Costa, E; Midao, L; Bosnic-Anticevich, S; Novellino, E; Bialek, S; Briedis, V; Mair, A; Rajabian-Soderlund, R; Arnavielhe, S; Bedbrook, A; Czarlewski, W; Annesi-Maesano, I; Anto, JM; Devillier, P; De Vries, G; Keil, T; Sheikh, A; Orlando, V; Larenas-Linnemann, D; Cecchi, L; De Feo, G; Illario, M; Stellato, C; Fonseca, J; Malva, J; Morais-Almeida, M; Pereira, AM; Todo-Bom, AM; Kvedariene, V; Valiulis, A; Bergmann, KC; Klimek, L; Mösges, R; Pfaar, O; Zuberbier, T; Cardona, V; Mullol, J; Papadopoulos, NG; Prokopakis, EP; Bewick, M; Ryan, D; Roller-Wirnsberger, RE; Tomazic, PV; Cruz, AA; Kuna, P; Samolinski, B; Fokkens, WJ; Reitsma, S; Bosse, I; Fontaine, JF; Laune, D; Haahtela, T; Toppila-Salmi, S; Bachert, C; Hellings, PW; Melén, E; Wickman, M; Bindslev-Jensen, C; Eller, E; O'Hehir, RE; Cingi, C; Gemicioglu, B; Kalayci, O; Ivancevich, JC; Bousquet, J; Bousquet, J; Hellings, PW; Aberer, W; Agache, I; Akdis, CA; Akdis, M; Aliberti, MR; Almeida, R; Amat, F; Angles, R; Annesi-Maesano, I; Ansotegui, IJ; Anto, JM; Arnavielle, S; Asayag, E; Asarnoj, A; Arshad, H; Avolio, F; Bacci, E; Bachert, C; Baiar-Dini, I; Barbara, C; Barbagallo, M; Baroni, I; Barreto, BA; Basagana, X; Bateman, ED; Bedolla-Barajas, M; Bedbrook, A; Bewick, M; Beghé, B; Bel, EH; Bergmann, KC; Bennoor, KS; Benson, M; Bertorello, L; Bialoszewski, AZ; Bieber, T; Bialek, S; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Blua, A; Marciniak, MB; Bogus-Buczynska, I; Boner, AL; Bonini, M; Bonini, S; Bosnic-Anticevich, CS; Bosse, I; Bouchard, J; Boulet, LP; Bourret, R; Bousquet, P; Braido, F; Briedis, V; Brightling, CE; Brozek, J; Bucca, C; Buhl, R; Buonaiuto, R; Panaitescu, C; Cabanas, MTB; Burte, E; Bush, A; Caballero-Fonseca, F; Caillaud, D; Caimmi, D; Calderon, MA; Camargos, PAM; Camuzat, T; Canfora, G; Canonica, GW; Cardona, V; Carlsen, KH; Carreiro-Martins, P; Carriazo, AM; Carr, W; Cartier, C; Casale, T; Castellano, G; Cecchi, L; Cepeda, AM; Chavannes, NH; Chen, Y; Chiron, R; Chivato, T; Chkhartishvili, E; Chuchalin, AG; Chung, KF; Ciaravolo, MM; Ciceran, A; Cingi, C; Ciprandi, G; Coehlo, ACC; Colas, L; Colgan, E; Coll, J; Conforti, D; De Sousa, JC; Cortés-Grimaldo, RM; Corti, F; Costa, E; Mc Costa-Dominguez; Al Courbis; Cox, L; Crescenzo, M; Cruz, AA; Custovic, A; Czarlewski, W; Dahlen, SE; D'Amato; Dario, C; da Silva, J; Dauvilliers, Y; Darsow, U; De Blay, F; De Carlo, G; Dedeu, T; Emerson, MDF; De Feo, G; De Vries, G; De Martino, B; Rubina, NPM; Deleanu, D; Demoly, P; Denburg, J; Devillier, P; Ercolano, SDC; Di Carluccio, N; Didier, A; Dokic, D; Dominguez-Silva, MG; Douagui, H; Dray, G; Dubakiene, R; Durham, SR; Du Toit, G; Dykewicz, MS; El-Gamal, Y; Eklund, P; Eller, E; Emuzyte, R; Farrell, J; Farsi, A; De Mello, JF; Ferrero, J; Fink-Wagner, A; Fiocchi, A; Fok-Kens, WJ; Fonseca, J; Fontaine, JF; Forti, S; Fuentes-Perez, JM; Gálvez-Romero, JL; Gamkrelidze, A; Garcia-Aymerich, J; Garcia-Cobas, CY; Garcia-Cruz, MH; Gemicioglu, B; Genova, S; Christoff, G; Gereda, JE; Van Wijk, RG; Gomez, RM; Gómez-Vera, J; Diaz, SG; Gotua, M; Grisle, I; Guidacci, M; Guldemond, N; Gutter, Z; Guzmán, M; Haahtela, T; Hajjam, J; Hernández, L; Houri-Hane, J; Huerta-Villalobos, YR; Humbert, M; Iaccarino, G; Illario, M; Ispayeva, Z; Ivancevich, JC; Jares, E; Jassem, E; Johnston, SL; Joos, G; Jung, KS; Just, J; Jutel, M; Kaidashev, I; Kalayci, O; Kalyoncu, AF; Karjalainen, J; Kardas, P; Keil, T; Keith, PK; Khaitov, M; Khaltaev, N; Kleine-Tebbe, J; Klimek, L; Kowalski, ML; Kuitunen, M; Kull, I; Kuna, P; Kupczyk, M; Kvedariene, V; Krzych-Falta, E; Lacwik, P; Larenas-Linnemann, D; Laune, D; Lauri, D; Lavrut, J; L, TT; Lessa, M; Levato, G; Li, J; Lieberman, P; Liplec, A; Lipworth, B; Carlsen, KCL; Louis, R; Lourenco, O; Luna-Pech, JA; Magnan, A; Mahboub, B; Maier, D; Mair, A; Majer, I; Malva, J; Mandajieva, E; Manning, P; Keenoy, EDM; Marshall, GD; Masjedi, MR; Maspero, JF; Mathieu-Dupas, E; Campos, JJM; Al Matos; Maurer, M; Mavale-Manuel, S; Mayora, O; Medina-Avalos, MA; Melén, E; Melo-Gomes, E; Meltzer, E; Menditto, E; Mercier, J; Miculinic, N; Mihaltan, F; Milenkovic, B; Moda, G; Mogica-Martinez, MD; Mohammad, Y; Momas, I; Monte-Fort, S; Monti, R; Bogado, DM; Morais-Almeida, M; Morato-Castro; Mösges, R; Mota-Pinto, A; Santo, PM; Mullol, J; Münter, L; Muraro, A; Murray, R; Naclerio, R; Nadif, R; Nalin, M; Napoli, L; Namazova-Baranova, L; Neffen, H; Niedeberger, V; Nekam, K; Neou, A; Nieto, A; Nogueira-Silva, L; Nogues, M; Novellino, E; Nyembue, T; O'Hehir, R; Odzhakova, C; Ohta, K; Okamoto, Y; Okubo, K; Onorato, GL; Cisneros, MO; Ouedraogo, S; Pali-Schöll, I; Palkonen, S; Panzner, P; Papadopoulos, NG; Park, HS; Papi, A; Passalacqua, G; Paulino, E; Pawankar, R; Pedersen, S; Pépin, JL; Pereira, AM; Persico, M; Pfaar, O; Phillips, J; Picard, R; Pigearias, B; Pin, I; Pitsios, C; Plavec, D; Pohl, W; Popov, TA; Portejoie, F; Potter, P; Pozzi, AC; Price, D; Prokopakis, EP; Puy, R; Pugin, B; Ross, REP; Przemecka, M; Rabe, KF; Raciborski, F; Raja-Bian-Soderlund, R; Reitsma, S; Ribeirinho, I; Rimmer, J; Riv-Ero-Yeverino, D; Rizzo, JA; Rizzo, MC; Robalo-Cordeiro, C; Rodenas, F; Rodo, X; Gonzalez, MR; Rodriguez-Mañas, L; Rolland, C; Valle, SR; Rodriguez, MR; Romano, A; Rodriguez-Zagal, E; Rolla, G; Roller-Wirnsberger, RE; Romano, M; Rosado-Pinto, J; Rosario, N; Rottem, M; Ryan, D; Sagara, H; Salimäki, J; Samolinski, B; Sanchez-Borges, M; Sastre-Dominguez, J; Scadding, GK; Schunemann, HJ; Scichilone, N; Schmid-Grendelmeier, P; Serpa, FS; Shamai, S; Sheikh, A; Sierra, M; Simons, FER; Sir-Oux, V; Sisul, JC; Skrindo, I; Solé, D; Somekh, D; Sonder-Mann, M; Sooronbaev, T; Sova, M; Sorensen, M; Sorlini, M; Spranger, O; Stellato, C; Stelmach, R; Stukas, R; Sunyer, J; Strozek, J; Szylling, A; Tebyricá, J; Thibaudon, M; To, T; Todo-Bom, A; Tomazic, PV; Toppila-Salmi, S; Trama, U; Triggiani, M; Ulrik, CS; Urrutia-Pereira, M; Valenta, R; Valero, A; Valiulis, A; Valovirta, E; Van Eerd, M; Van Ganse, E; Van Hague, M; Vandenplas, O; Ventura, MT; Vezzani, G; Vasankari, T; Vatrella, A; Verissimo, MT; Viart, F; Viegi, G; Vicheva, D; Vontetsianos, T; Wagenmann, M; Walker, S; Wallace, D; Wang, DY; Waserman, S; Werfel, T; Westman, M; Wickman, M; Williams, DM; Williams, S; Wilson, N; Wright, J; Wroczynski, P; Yakovliev, P; Yawn, BP; Yiallouros, PK; Yorgancioglu, A; Yusuf, OM; Zar, HJ; Zhang, L; Zhong, N; Zernotti, ME; Zhanat, I; Zidarn, M; Zuberbier, T; Zubrinich, C; Zurkuhlen, A
    Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12143 users were registered. A total of 6949 users reported at least one VAS data recording. Among them, 1887 users reported >= 7 VAS data. About 1195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR >= 70% and PDC <= 1.25), 51 (4.23%) were partly adherent (MPR >= 70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.