Browsing by Author "Dikici, DS"

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    Reliability and validity of Turkish Version of DSM-5 Psychosis Scale
    Herdem, A; Dikici, DS; Aydemir, Ö
    Objective: In this study we evaluated the reliability and validity of the Turkish version of DSM-5 Psychosis Scale developed in order to evaluate severity of psychosis in adult patients. Methods: This study was carried out with patients who met the diagnostic criteria for any psychotic disorder according to DSM-5 criteria and who are undergoing treatment in the inpatient and outpatient wards of Psychiatry Department of Celal Bayar University Medical School. Except for psychotic disorders patients with any mental or physical disease were excluded. A total of 49 patients (40 patients with schizophrenia, six patients with not otherwise specified psychotic disorder, three patients with schizoaffective disorder) were included in the study. One hundred and one volunteers without any mental or physical disease were included as the healthy control group. Reliability analysis was based on internal consistency and item-total score correlation. Validity analysis was based on exploratory factor analysis, comparison of mean scores of the patient and healthy control groups and ROC analysis. Results: The mean age of the study group was 26.0 +/- 10.3 years and 52.7% of the sample group (n = 79) were female. Sixty-nine point three percent of the study group were college graduates, 8% primary school graduates, 19.3% is also high school graduates. Mean disease duration was 17.1 +/- 9.7 years in the psychotic disorder group. The internal consistency of the Psychosis Scale was 0.91 and, item-total correlation coefficients of the Psychosis Scale were between 0.25 and 0.82. In the factor analysis, for sample adequacy Kaiser- Meier-Olkin (KMO) coefficient was found as 0.81 and Bartlett coefficient as 1.03. Single-factor solution was obtained and the eigenvalue is 5.12, representing 64.0% of the total variance. Factor loadings of the items of the scale were between 0.33 and 0.88. The mean of score was 11.00 +/- 5.20 in patient group while it was calculated as 0.21 +/- 1.21 in control group. The area under the curve was calculated as 0.98 in the ROC analysis. Conclusion: These results indicate that the Turkish version of Psychosis Scale is reliable and valid.
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    Reliability and Validity of the Turkish Version of the Burden Assessment Scale
    Aydemir, Ö; Dikici, DS; Akdeniz, F; Kalayci, F
    Background: In this study, it is aimed to evaluate the reliability and validity of the Turkish version of the Burden Assessment Scale. Methods: The study was carried out on 100 volunteers who were caregivers of in-or outpatients at a university hospital, department of psychiatry. The diagnoses of the patients were schizophrenia (25%), bipolar disorder (22%), major depressive disorder (24%), and anxiety disorder (29%). The mean duration of the illness was 8.2 +/- 8.7 years. For the concurrent validity, the Perceived Family Burden Scale and the Zarit Caregiver Burden Scale were used. In the statistical analyses, internal consistency, item-total score correlation, explorative factor analysis, correlation with other scales were calculated. Results: The Turkish version of the Burden Assessment Scale was prepared after the translation and back-translation of the original scale and after the consensus on the translated form. In the internal consistency analysis, Cronbach alpha coefficient was found to be 0,894 and item-total score correlation coefficients were between 0.297 and 0.742. In the explorative factor analysis, a five-factor solution explaining 67.2% of the total variance was obtained and the conceptual themes of the factors were limitations in daily life, negative emotions, worry for the patient, losses of the caregiver, and disruption in activities. The correlation of the Burden Assessment Scale with the Perceived Family Burden Scale was r=0.485 and with the Zarit Caregiver Burden Scale was r=0.610. Conclusion: It is demonstrated that the Turkish version of the Burden Assessment Scale which is convenient in the milder forms of psychiatric disorders and which is developed for the assessment burden of patients on their caregivers is reliable and valid. (Archives of Neuropsychiatry 2012; 49: 276-280)
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    Quality of Life and Associated Risk Factors in Caregivers of Patients with Obsessive Compulsive Disorder
    Dikici, DS; Eser, E; Çökmüs, FP; Demet, MM
    INTRODUCTION: Obsessive compulsive disorder (OCD) is a chronic disease that affects social relationships, and occupational and academic performance of patients and their relatives due to cognitive, emotional, and behavioural aspects of the disease. Quality of life (QoL) in relatives of patients with OCD has previously been reported and compared with caregivers of patients with other psychiatric conditions. However, there are few studies available in the literature regarding the causality of QoL in caregivers of patients with OCD. OBJECTIVE: The aim of this study was to evaluate QoL of caregivers of patients with OCD and predictors of QoL of the family caregivers. METHODS: The study population comprised of 68 patients with OCD and their caregivers. The dependent variable of this study is QoL of caregivers as assessed by the short version of the World Health Organization Quality of Life questionnaire (WHOQOL-BREF-TR). The Structured Clinical Interview for DSM-IV/Clinical Version (SCID-I/CV), Yale-Brown obsessive-compulsive scale (Y-BOCS), Y-BOCS symptom checklist, Hamilton Depression Rating Scale (HAM-D), and WHOQOL-BREF-TR were completed by the patients, whereas the SCID-I/CV, WHOQOL-BREF-TR, and Burden Assessment Scale (BAS) were completed by the caregivers. Student's t-test, MWU, ANOVA, Kruskal-Wallis ANOVA, and Spearman's correlations were used in univariate analyses, and multiple linear regression tests were run in multivariate analyses. Critical VIF values were taken as 5.0 for detecting collinearity among independent variables in the regression analyses. Type 1 error was taken as 0.05 in the analyses. RESULTS: Linear regression analysis showed that caregivers' sex, education level, occupational status, disease burden, and patients' sex, physical QoL, and disease severity were predictors of caregivers' QoL. Moreover, disease burden was the only common predictor that affected all four dimensions (physical, psychological, social relations, environmental) of the caregiver's QoL, and as the perceived disease burden increased, the caregiver's QoL deteriorated.
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    The validity and reliability of DSM-5 separation anxiety disorder severity scale-adult form
    Çöldür, EÖ; Çökmüs, FP; Dikici, DS; Aydemir, Ö
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    Quickly diagnosed and treated prepubertal Type 1 narcolepsy case
    Çökmüs, FP; Aydin, O; Dikici, DS; Sapmaz, SY
    Excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucination are the classic tetrad of narcolepsy. It has been shown that narcolepsy, a chronic and disabling disease, starts in childhood and adolescence rather than adulthood. The International Classification of Sleep Disorder (ICSD-3) classifies narcolepsy into Type 1 (narcolepsy with cataplexy) and Type 2 (narcolepsy without cataplexy). There is low awareness and knowledge of narcolepsy among the general public, primary care physicians, and sleep specialists. It has been shown that the lack of recognition of disease symptoms delayed the diagnosis of narcolepsy from 8.7 to 22.1 years. In this case report, we will discuss the case of Type 1 narcolepsy, which started in the prepubertal period and was diagnosed and treated in a short period of time.
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    Evaluation of psychosocial functioning in the acute treatment term of major depressive disorder: A 16-week multi-centered follow-up study
    Altunsoy, N; Dikici, DS; Cökmüs, FP; Özkan, HM; Ascibasi, K; Alçi, D; Kuru, E; Yüzeren, S; Aydemir, O
    Objective: Major depressive disorder is the leading cause of non-fatal burden, and disability in adulthood. Even though depression is well-treated in the acute term,psychosocial functioning does not get back to the premorbid level most of the time. In this present study, it is aimed to evaluate the outcome of the acute term treatment of major depressive disorder in terms of psychosocial functioning. Methods: The study is an open-label, observational, multi-center follow-up study for four months of patients with major depressive disorder according to DSM-5. Patients were evaluated with Montgomery Asberg Depression Rating Scale (MADRS), Sheehan Disability Scale (SDS) and Short Form-36 (SF-36) at the beginning, and at the 2., 4., 8., 12. and 16.weeks. Results: 100 patients were invited to the study and 56 patients completed the study.As a result of the treatment, the mean MADRS and SDS scores decreased significantly. All domains of SF-36 were improved significantly with the treatment. Unfortunately patients suffering from MDD could not reach the normative data,especially on the domains of social functioning, role emotional, pain, and general health perception. Treatment outcomes show that SNRI users presented higher scores on the domains of pain and physical functioning. However SSRI users showed better outcomes on the domains of mental health and vitality. Conclusion: Our research corroborated that even patients gain symptomatic remission in MDD treatment, psychosocial dysfunction persists. It is also concluded that different antidepressant options may act differently on treatment outcomes.
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    Reliability and validity of Turkish version of biological rhythms interview of assessment in neuropsychiatry
    Aydemir, O; Akkaya, C; Altinbas, K; Kora, K; Dikici, DS; Akdeniz, F; Kalayci, F; Oral, ET; Vahip, S
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    Evaluation of Emotional Adverse Effects of Antidepressants A Follow-up Study
    Ascibasi, K; Cökmüs, FP; Dikici, DS; Özkan, HM; Alçi, D; Altunsoy, N; Kuru, E; Yüzeren, S; Aydemir, Ö
    Purpose/Background Emotional adverse effects due to antidepressant use may cause difficulties for the clinician in the treatment of depression. In this prospective study, the emotional adverse effects of antidepressants were evaluated in various aspects. Methods/Procedures Ninety eight patients diagnosed with major depressive disorder were included in the study. At 2nd, 4th, 8th, 12th, and 16th weeks, patients were assessed with Montgomery-Asberg Depression Rating Scale (MADRS), and the antidepressant dose was increased in patients with less than a 50% reduction at each visit compared with the initial MADRS score. The Oxford Questionnaire on the Emotional Side-effects of Antidepressants (OQESA) was used at the 8th-week and 16th-week visits. Findings/Results A significant difference is found in the OQESA score at the 8th-week visit compared with the 16th-week assessment (P < 0.001, t = 5.73). There were significant correlations between MADRS scores and OQESA scores both at the 8th (r = 0.346, P = 0.05) and the 16th (r = 0.490, P < 0.001) weeks. In regression analyses, at eighth-week assessment, MADRS score (B = 1.487, P = 0.002) and selective serotonin reuptake inhibitor use (B = 14.014, P = 0.023) had a significantly predicted OQESA score. Implications/Conclusions In this study, it is found that, as the rate of remitted patients is increased, OQESA scores get decreased, and furthermore, the OQESA score of the remitted group is statistically low when compared with that of the nonremitted group at the 8th- and 16th-week visits. Oxford Questionnaire on the Emotional Side-effects of Antidepressants and MADRS scores are significantly correlated in all assessments. These results suggest that the score obtained from OQESA may be related not only to the emotional adverse effects of antidepressants but also to the residual symptoms of depression.
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    Reliability and validity of Turkish form of the personality inventory for DSM-5 adult version
    Cökmüs, FP; Yüzeren, S; Aydin, O; Aydin, PÜ; Öztekin, S; Akdeniz, F; Dikici, DS; Çöldür, EÖ; Balikçi, K; Köroglu, E; Aydemir, Ö
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    Evaluation of psychosocial and neurocognitive functioning in the acute treatment term of major depressive disorder: preliminary results
    Alci, DK; Cokmus, FP; Altunsoy, N; Ascibasi, K; Ozkan, HM; Dikici, DS; Yuzeren, S; Aydemir, O