Browsing by Author "Dilber Y."

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    The role of CAPE in PI3K/AKT/mTOR activation and oxidative stress on testis torsion
    (Elsevier GmbH, 2016) Dilber Y.; Inan S.; Ercan G.A.; Sencan A.
    Ischemia reperfusion injury arises from testicular torsion resulting in a loss of spermatogenesis and significant germ cell apoptosis. This study evaluates the prooxidant/antioxidant effects of caffeic acid phenethyl ester (CAPE) through PI3K/AKT/mTOR signal pathways on testis torsion. A total of (28) male Wistar rats were divided randomly into 4 groups (n= 7 for each group):group A (sham) group,group B torsion/detorsion group, group C (saturation group, during four days of CAPE, one dose (10. μmol/kg, i.p)) and group D (a single dose of CAPE 2 h after torsion and before detorsion). At the end of the study, unilateral orchiectomies were performed for measurements of MDA and 8OHdG levels, histopathologic and immunohistochemical and TUNEL apoptotic cell examination. Testicular torsion-detorsion led to a significant decrease in the mean values of the Johnsen's scores and a significant increase in the apoptotic cell values of group B. There were no significant differences between group D and group A. In addition, the MDA and 8OHdG levels increased significantly in group B. The MDA and 8OHdG values were lower in group D. However, the 8OHdG levels were higher in group C than the groups A and D. On the other hand, CAPE suppresses mTOR activation and reduces the apoptosis on ischemia/reperfusion damage in rat testis. These results demonstrate that CAPE suppresses mTOR activation and reduces the apoptosis on ischemia/reperfusion damage in rat testis. © 2015 Elsevier GmbH.
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    Investigation of the effects of fan control technique on energy consumption in industrial refrigerated display cabinet: An experimental study
    (SAGE Publications Ltd, 2024) Koşan M.; Dilber Y.; Erten S.; Bahar E.M.; Erdoğmuş F.N.; Aktaş M.; Öder M.
    With the increase in electricity consumption and price, energy efficiency in industrial refrigeration systems becomes an even more important issue. The performance of the industrial refrigeration system can be reported by creating energy labeling according to the energy efficiency index value. In this study, the industrial refrigeration system was evaluated in terms of energy performance with proposed a fan control technique and performed an environmentally friendly design using propane (R290) refrigerant. In addition, a new control process was developed for the management of evaporator and condenser fans, and the effect of this process on the cooled package temperatures and energy consumption was investigated. With this new technique, a 25.2% improvement was achieved in the total energy consumption of the industrial refrigeration system. It was observed that the cooled package temperatures were between −1 and +5°C throughout the experiment. The EEI value of the industrial refrigeration system has increased from class “E” to class “D” using a new control technique. © IMechE 2022.