Browsing by Author "Doğan A."

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    Coralligenous assemblages along their geographical distribution: Testing of concepts and implications for management
    (John Wiley and Sons Ltd, 2020) Çinar M.E.; Féral J.-P.; Arvanitidis C.; David R.; Taşkin E.; Sini M.; Dailianis T.; Doğan A.; Gerovasileiou V.; Evcen A.; Chenuil A.; Dağli E.; Aysel V.; Issaris Y.; Bakir K.; Nalmpantı M.; Sartoretto S.; Salomidi M.; Sapouna A.; Açik S.; Dimitriadis C.; Koutsoubas D.; Katağan T.; Öztürk B.; Koçak F.; Erdogan-Dereli D.; Önen S.; Özgen Ö.; Türkçü N.; Kirkim F.; Önen M.
    1.The coralligenous habitat was studied at the large Mediterranean scale, by applying a standardized, non-destructive photo-sampling protocol, developed in the framework of the CIGESMED project. 2.The results provided evidence to support the following statements: (a) the assemblage pattern is not homogeneously distributed across the four Mediterranean ecoregions studied (biotic gradients hypothesis); and (b) the assemblage pattern does not change significantly when the information is aggregated to higher taxonomic levels (taxonomic sufficiency hypothesis). 3.Surrogate taxonomic categories higher than species, such as genus and family, can be used to reveal the multivariate pattern of the coralligenous assemblages. 4.Although preliminary at the pan-Mediterranean scale, these outcomes set the scene for future comparisons as more data sets become available but also for comparisons between taxonomic and functional patterns. © 2020 John Wiley & Sons, Ltd.
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    Current status (as of end of 2020) of marine alien species in Turkey
    (Public Library of Science, 2021) Çinar M.E.; Bilecenoğlu M.; Yokeş M.B.; Öztürk B.; Taşkin E.; Bakir K.; Doğan A.; Açik Ş.
    The 2020's update of marine alien species list from Turkey yielded a total of 539 species belonging to 18 taxonomic groups, 404 of which have become established in the region and 135 species are casual. A total of 185 new alien species have been added to the list since the previous update of 2011. The present compilation includes reports of an ascidian species (Rhodosoma turcicum) new to the marine fauna of Turkey and range extensions of six species. Among the established species, 105 species have invasive characters at least in one zoogeographic region, comprising 19% of all alien species. Mollusca ranked first in terms of the number of species (123 species), followed by Foraminifera (91 species), Pisces (80 species) and Arthropoda (79 species). The number of alien species found in seas surrounding Turkey ranged from 28 (Black Sea) to 413 (Levantine Sea). The vectoral importance of the Suez Canal diminishes when moving from south to north, accounting for 72% of species introductions in the Levantine Sea vs. only 11% of species introductions in the Black Sea. Most alien species on the coasts of Turkey were originated from the Red Sea (58%), due to the proximity of the country to the Suez Canal. Shipping activities transported 39% of alien species, mainly from the Indo-Pacific area (20%) and the Atlantic Ocean (10%). Misidentified species (such as Pterois volitans, Trachurus declivis, etc.) and species those classified as questionable or cryptogenic were omitted from the list based on new data gathered in the last decade and expert judgements. The documented impacts of invasive species on socio-economy, biodiversity and human health in the last decade as well as the legislation and management backgrounds against alien species in Turkey are presented. © 2021 Çinar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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    Clinical outcomes of cyclin-dependent kinase 4–6 (CDK 4–6) inhibitors in patients with male breast cancer: A multicenter study
    (Churchill Livingstone, 2022) Yıldırım H.Ç.; Mutlu E.; Chalabiyev E.; Özen M.; Keskinkılıç M.; Ön S.; Çelebi A.; Dursun B.; Acar Ö.; Kahraman S.; Aykan M.B.; Kaman Ö.; Doğan A.; Erdoğan A.P.; Melisa Celayir Ö.; Günenç D.; Güven D.C.; Vedat Bayoğlu İ.; Yavuzşen T.; Hacıbekiroğlu İ.; İnanç M.; Kılıçkap S.; Yalçın Ş.; Aksoy S.
    Background: Since breast cancer is less common in men than in women, data on the use of new therapeutic agents, including cyclin-dependent kinase 4–6 (CDK 4–6) inhibitors, are limited in patients with metastatic hormone receptor positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) male breast cancer. Therefore; we aimed to investigate the treatment responses of metastatic HR+, HER2-male breast cancer patients treated with CDK 4–6 inhibitors in a multicenter real-life cohort. Methods: Male patients with a diagnosis of HR+ and HER2-metastatic breast cancer, treated with any CDK 4–6 inhibitor, were included in the study. Demographic and clinical characteristics of the patients were recorded. We aimed to determine progression-free survival (PFS) time, response rates and drug related side effects. Results: A total 25 patients from 14 institutions were recruited. The mean age at diagnosis was 57 years. Median follow-up was 19.53 (95% CI: 14.04–25.02) months. The overall response rate was 60%. While the median PFS was 20.6 months in the whole cohort, it wasn't reached in those using CDK 4–6 inhibitors in first line and 10 months in the subsequent lines (p:0.009). No new adverse events were encountered. Conclusion: In our study, we found that CDK 4–6 inhibitors are effective and safe options in men with HR+ and HER2-metastatic breast cancer as in women. Our results support the use of CDK 4–6 inhibitor-based combinations in the first-line treatment of HR+ and HER2-metastatic male breast cancer. © 2022
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    Geodetic evidence for aseismic fault movement on the eastern segment of the Gediz Graben system (western Anatolia extensional province, Turkey) and its significance for settlements
    (Akademiai Kiado ZRt., 2022) Doğan A.; Kaygusuz Ç.; Tiryakioğlu İ.; Yigit C.O.; Sözbilir H.; Özkaymak Ç.; Turgut B.
    Aseismic dip-slip normal fault displacement related to numerous fast-slipping active faults was recently observed in several localities in the western Anatolia extensional province. Still, the characteristics of displacements along with the behavior of individual fault segments are poorly known. Here we analyze an aseismically active normal fault affecting the settlement area of the Sarıgöl district, Turkey, at the surface rupture area of the 1969 magnitude 6.5 Alaşehir earthquake. A precise leveling method was implemented in this area between July 2017 and 2020, to determine the vertical movements of the hanging wall relative to the footwall of the Sarıgöl fault. The yearly vertical movement on the surface along Profile 1 was − 7.0, − 7.3, and − 7.0 cm, respectively, for the three years starting in July 2017, and on Profile 2 it was − 7.7, − 8.7, and − 7.8 cm for the same time period. This persistent deformation, especially in the summer and fall seasons, suggests that may be related to groundwater level changes. Intensive agriculture is conducted in the region and a high level of irrigation activity in the summer period causes a decrease in groundwater levels. In addition, the continued deformation together with intensive precipitation in winter and spring despite high groundwater levels leads to the idea that tectonic creep movement could be a second reason for the deformation in the area. In the current study, the most important result is that the aseismic deformation starting after the 1969 Mw6.5 Alaşehir earthquake still continues rapidly today with a velocity of 70–80 mm/year down-dip. This indicates that the damage zone of the Sarıgöl fault is not appropriate for settlements in the Sarıgöl district due to continuous high amounts of vertical displacement, and that appropriate building policy and awareness campaigns are needed. © 2022, Akadémiai Kiadó.
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    Unpublished Mediterranean and Black Sea records of marine alien, cryptogenic, and neonative species
    (Regional Euro-Asian Biological Invasions Centre, 2023) Ragkousis M.; Zenetos A.; Souissi J.B.; Hoffman R.; Ghanem R.; Taşkın E.; Muresan M.; Karpova E.; Slynko E.; Dağlı E.; Fortič A.; Surugiu V.; Mačić V.; Trkov D.; Bahri W.R.; Tsiamis K.; Ramos-Espla A.A.; Petović S.; Ferrario J.; Marchini A.; Sconfietti R.; Ammar I.; Alo A.; Edelist D.; Begun T.; Teaca A.; Tari G.; Huseyinoglu M.F.; Karachle P.K.; Dogrammatzi A.; Apostolopoulos G.A.; Crocetta F.; Kytinou E.; Digenis M.; Skouradakis G.; Tomas F.; Bariche M.; Kaminas A.; Konida K.; Deidun A.; Marrone A.; Fraschetti S.; Mihneva V.; Bianchi C.N.; Morri C.; Gerovasileiou V.; Lipej L.; Sini M.; Mangialajo L.; Zotou M.; Skolka M.; Azzurro E.; Vella A.; Dailianis T.; Grigoriou P.; Jimenez C.; Tsirintanis K.; Oikonomidis G.; Mancini E.; Papadakis O.; Di Martino V.; Chatzigeorgiou G.; Amor M.M.B.; Vernadou E.; Arda Y.; Minasidis V.; Azzola A.; Hadjioannou L.; Montefalcone M.; Baldacchino Y.; Stancanelli B.; Bonifazi A.; Occhipinti-Ambrogi A.; Smeraldo S.; Evans J.; Kondylatos G.; Falautano M.; Castriota L.; Lamprou A.; Rizgalla J.; Mavrič B.; Papadimitriou E.; Kersting D.K.; Schembri P.J.; Khamassi F.; Nikolaou A.; Ballesteros E.; Dimitriadis C.; García M.; Anastasiadis A.; Kalogirou S.; Nalmpanti M.; Altamirano M.; Grech D.; Mavrouleas D.; Vella N.; Darmanin S.A.; Dragičević B.; Poursanidis D.; Tsatiris A.; Corsini-Foka M.; Orlando- Bonaca M.; Insacco G.; Tsalapatis A.; Scannella D.; Tiralongo F.; Verdura J.; Vitale S.; Valsamidis M.A.; Bazairi H.; Mannino A.M.; Virgili R.; Coccia F.C.; Zrelli R.E.; Nikolidakis S.; Rabaoui L.J.; Yapıcı S.; Zaouali J.; Zava B.; Agrotis N.; Bilecenoglu M.; Çinar M.E.; Moraitis M.L.; Albano P.G.; Kaddouri N.; Kosma I.; Falsone F.; Fossati V.; Geraci M.L.; Zamuda L.L.; Mancuso F.P.; Petrou A.; Resaikos V.; Aydın İ.; Batjakas I.E.; Bos A.R.; Ouamari N.E.; Giallongo G.; Kampouris T.E.; Amor K.O.-B.; Doğan A.; Dulčić J.; Okudan E.Ş.; Rilov G.; Rosso A.; Royo L.; Selfati M.; Gaglioti M.; Giakoumi S.; Kousteni V.; Micu D.; Nicoară M.; Orfanidis S.; Papatheodoulou M.; Tempesti J.; Triantaphyllou M.; Tsourou T.; Yalgın F.; Baltag E.; Cerim H.; Filiz H.; Georgiadis C.G.; Papadamakis P.; Rammou D.L.; Samargiu M.D.; Sciuto F.; Sinopoli M.; Türker A.; Chiarore A.; Tamburello L.; Karray S.; Hassen B.; Katsanevakis S.
    To enrich spatio-temporal information on the distribution of alien, cryptogenic, and neonative species in the Mediterranean and the Black Sea, a collective effort by 173 marine scientists was made to provide unpublished records and make them open access to the scientific community. Through this effort, we collected and harmonized a dataset of 12,649 records. It includes 247 taxa, of which 217 are Animalia, 25 Plantae and 5 Chromista, from 23 countries surrounding the Mediterranean and the Black Sea. Chordata was the most abundant taxonomic group, followed by Arthropoda, Mollusca, and Annelida. In terms of species records, Siganus luridus, Siganus rivulatus, Saurida lessepsianus, Pterois miles, Upeneus moluccensis, Charybdis (Archias) longicollis, and Caulerpa cylindracea were the most numerous. The temporal distribution of the records ranges from 1973 to 2022, with 44% of the records in 2020–2021. Lethrinus borbonicus is reported for the first time in the Mediterranean Sea, while Pomatoschistus quagga, Caulerpa cylindracea, Grateloupia turuturu, and Misophria pallida are first records for the Black Sea; Kapraunia schneideri is recorded for the second time in the Mediterranean and for the first time in Israel; Prionospio depauperata and Pseudonereis anomala are reported for the first time from the Sea of Marmara. Many first country records are also included, namely: Amathia verticillata (Montenegro), Ampithoe valida (Italy), Antithamnion amphigeneum (Greece), Clavelina oblonga (Tunisia and Slovenia), Dendostrea cf. folium (Syria), Epinephelus fasciatus (Tunisia), Ganonema farinosum (Montenegro), Macrorhynchia philippina (Tunisia), Marenzelleria neglecta (Romania), Paratapes textilis (Tunisia), and Botrylloides diegensis (Tunisia). © Ragkousis et al.
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    Non-Indigenous Species (NIS) Know No Geopolitical Borders—An Update of NIS in the Aegean Sea
    (Multidisciplinary Digital Publishing Institute (MDPI), 2025) Zenetos A.; Doğan A.; Bakir A.K.; Chatzigeorgiou G.; Corsini-Foka M.; Dağli E.; Evangelopoulos A.; Meriç E.; Stoumboudi M.; Taşkin E.; Yokeş M.B.; Galanidi M.
    In this work, combined efforts by Greek and Turkish scientists produced an updated validated NIS inventory of the Aegean ecoregion, covering 120 years of records up to August 2024. Of the 342 NIS currently present in the Aegean Sea, the majority (281 species) have invaded the South Aegean, followed by the North Aegean (128 species out of 206 NIS). A total of 73 species were added to the list, while 56 were removed. Overall, unaided spread of Lessepsian immigrants from the Levantine Sea and shipping are equally responsible for NIS reported at the regional level. An increase in publications addressing NIS matches the upward trend of NIS since the mid-1990s, which continues to the present day. While unaided introductions of Lessepsian species and/or direct introductions via the Suez Canal peaked in the South Aegean during 2000–2005, they peaked in 2012–2017 in the North Aegean—a decade later. The opposite pattern was observed in ship-transferred NIS. The spatial distribution of introduction hotspots largely reflects the following phenomena/processes: unaided introduction is witnessed initially in the southeastern Aegean Sea; monitoring efforts are concentrated in vulnerable and at-risk areas; and research efforts relate to the spatial allocation of institutions and marine experts working on marine NIS along the Aegean coasts. © 2024 by the authors.