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  1. Home
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Browsing by Author "Duruöz, MT"

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    Effects of inhaled corticosteroids on bone mineral density, bone formation and resorption markers and quality of life in patients with premenopausal asthma
    Cerrahoglu, L; Susin, A; Celik, P; Uyanik, BS; Duruöz, MT
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    Hand function assessment in patients receiving haemodialysis
    Duruöz, MT; Cerrahoglu, L; Dincer-Turan, Y; Kürsat, S
    Objective: To assess the usefulness of Duruozs Hand Index (DHI) in patients undergoing haemodialysis. Methods: Patients receiving haemodialysis for more than 2 months were recruited randomly. Demographic, clinical and functional characteristics of patients were evaluated. Functional assessment was performed with DHI, Hand Functional Index (HFI), Health Assessment Questionnaire (HAQ), Purdue Pegboard, grip strength and 3 kinds of pinch strengths. DHI was correlated (Spearman's) with the other functional parameters in assessing the convergent validity and with non-functional parameters in assessing the divergent validity Results: Sixty patients with a mean age of 50.05 were recruited. The average duration of haemodialysis was 55.02 months. DHI is significantly correlated with HAQ, HFI, Purdue Pegboard scores, grip strength and 3 types of pinch strengths while no significant correlation was found with non-functional parameters. Conclusions: DHI is a practical scale which is efficient in assessing accurately the functional disability of the hand in patients receiving haemodialysis.
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    Relationship between hip geometry (fracture index) and fracture risk in males
    Cerrahoglu, L; Gulesan, Y; Gumuser, FG; Duruöz, MT
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    Clinical and radiological characteristics of spondyloarthropathy
    Turan, Y; Duruöz, MT; Cerrahoglu, L
    Objective: The objective of this study is to determine the clinical characteristics of patients with spondyloarthropaties ( SpA). Patients and Methods: One hundred - twenty patients that match European Spondyloarthropaties Study Group (ESSG) diagnostic criteria, were included in this study. There were 48 ankylosing spondylitis ( AS), 42 reactive arthritis (ReA), 9 psoriatic arthritis (PsA), 3 enteropathic arthritis ( EA) and 18 undifferentiated SpA (uSpA) patients. Demographic data, clinical parameters and grade of sacroiliitis were assessed. Enthesitis were evaluated by the Mander Enthesis Index (MEI). Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) evaluated disease activity and functional status in AS patients, respectively. Results: The most frequently seen symptom was night pain (55.1%) and the most frequently seen radiographic involvement was right sacroiliitis (95.8%). Epin calcanei was most frequently observed in PsA (55.5%) and EA (33.3%) patients. The incidence of enthesitis in patients with SpA was 86.7%. Uveitis and heel pain were most commonly found respectively in AS (16.7%), and ReA (47.6%) patients. Conclusion: Whereas patients with SpA had similar clinical symptoms, their most common complaint was night pain. We think that it should be keep in mind while medical treatment is put in order.
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    Quality of life in patients with ankylosing spondylitis
    Turan, Y; Duruöz, MT; Cerrahoglu, L
    The aims of this study were to evaluate quality of life (QOL) in patients with ankylosing spondylitis (AS) and to determine the relationship between QOL and clinical condition/functional status. Forty-six AS patients (37 males) were included in the study. The demographic data of the patients were recorded. Disease activity Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), enthesitis involvement Mander Ehthesis Index (MEI), functional evaluation Bath Ankylosing Spondylitis Functional Index (BASFI), and quality of life Short-Form 36 (SF-36) were assessed. The mean age of the patients was 39.2 (SD: 11. 46) years. Most MEI was found related to physical function (P = 0.014), physical role (P = 0. 01), pain (P = 0.002) and vitality (P = 0.004) in SF-36 subgroups. Among the subgroups, the best correlations with the general health was found in BASDAI (P = 0.014) and secondly in MEI (P = 0.038). None of the mental health and social function subgroups had any significant correlation with any of the parameters (P > 0.05). A significant relationship was found between the emotional role and BASFI, and chest expansion (P = 0.004). Clinical and functional state were affecting QOL of patients with AS. It has been found out that in patients with AS, the QOL subgroups are mostly related with enthesis involvement.
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    Development and validation of a functional disability index for chronic low back pain
    Duruöz, MT; Özcan, E; Ketenci, A; Karan, A
    OBJECTIVE: To develop a valid and reliable functional disability scale for chronic low back pain (CLBP). METHODS: Inpatients and outpatients suffering from low back pain (LBP) for at least 3 months were selected randomly. Patients with inflammatory LBP were not recruited. Interrater reliability and Cronbach's alpha were examined. Face, content, convergent and divergent validities were investigated. Factor Analysis and pearson's correlation coefficients (r) were performed. RESULTS: 112 patients (71 females) with a mean age of 39.93 (SD: 12.92) answered the 66 questions on the provisional scale. Elimination left 18 daily activity questions. The interrater reliability of the scale was 0.79 and Cronbach's alpha was 0.90. Face and content validities were determined. It showed good convergence with the Quebec Back Pain Disability Scale (r: 0.82), the Oswestry Disability Index (r: 0.76), Waddell's Functional Index (r: 0.68), and the Visual Analog Scale of Handicap (VAS-handicap) (r: 0.49) The scale showed no significant or fair relationship (divergence) with VAS-lumbar, VAS-radicular, Beck Depression Inventory, morning stiffness, night pain, finger tip-ground distance, radicular pain duration, or modified Schober's index. The scale had two main factors. First represents activities implicating forward bending and second represents standing activities. CONCLUSION: A practical functional disability scale for CLBP was developed and validated.
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    Turkish Translation and Patient Evaluation of the ASAS/EULAR Recommendations-Patient Version for the Management of Ankylosing Spondylitis
    Özgöçmen, S; Duruöz, MT
    Objective: The aim of this study was to evaluate the Turkish translation of the patient version of the Assessment in Spondyloarthritis International Society (ASAS) and European League Against Rheumatism (EULAR) recommendations for the management of ankylosing spondylitis ( AS) by the patients. Material and Methods: Twelve members of the Ankylosing Spondylitis Patient Society of Turkey participated in the study. All were patients suffering from AS and all items of the recommendations were evaluated for the exact Turkish wording, meaning and comprehensibility by Turkish AS patients. All items were discussed and scored by the patients. Results: The median age of the 12 patients ( 4 female and 8 male) was 39.5 and disease duration was 11.5 years. The median Bath Ankylosing Spondylitis Disease Activity Index and Bath Ankylosing Spondylitis Functional Index were 4.0 and 3.42, respectively. Patients were agreed on each of the 10 items with a mean rate of >80%, and scored the overall recommendations with a mean score of 9.83 +/- 0.39. Conclusion: The patient version of the ASAS/EULAR recommendations for the management of AS has been successfully translated into Turkish and all of the patients reached an overall agreement on these recommendations. Treatment guidelines or recommendations that were composed using a medical language that could not be clearly understood by the patients should be translated into common vernacular in order to disseminate knowledge and maintain the patients' participation. ( Turk J Rheumatol 2009; 24: 190-5)
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    The frequency and associated factors of low back pain among a younger population in Turkey
    Çakmak, A; Yücel, B; Özyalçin, SN; Bayraktar, B; Ural, HI; Duruöz, MT; Genç, A
    Study Design. Open design cross-sectional questionnaire. Objectives. The aims of this study are to determine the frequency of low back pains in the younger population and the factors that have an influence on this frequency. Summary of Background Data. Low back pain is one of the most important social problems that causes injuries in the younger population. Low back pain frequency is around 30% among adolescents, and 88% of those with low back pain experiences in adolescence have low back pain in later years. Therefore, identifying and, if possible, preventing the associated factors in adolescence and young adulthood is essential for the solution of this social problem. Methods. A total of 1,552 students from a total of 8,000 who had come from all parts of Turkey for university registration accepted to participate in the study and were given a questionnaire about low back pain experiences, disability, and possible associated factors. Results. Low back pain frequency was found to be 40.9%. This rate increases with age. Abandonment of moderate level physical activity and traumas such as slipping on ice and falling down the stairs were identified as associated factors. Conclusions. Regular physical activity and the prevention of falls might be ways for decreasing the frequency of low back pain experiences among the youth and significantly influencing the frequency of low back pain in adult population.
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    Evaluation of metabolic syndrome in patients with chronic low back pain
    Duruöz, MT; Turan, Y; Gürgan, A; Deveci, H
    The aim of our study was to investigate the frequency of the metabolic syndrome in chronic low back pain and evaluate the differences in clinical and functional parameters in chronic low back pain patients with and without metabolic syndrome. Patients complaining of low back pain complaint lasting for at least 2 months were included in the study. In order to establish functional deficiency, Roland-Morris Disability Questionnaire, Istanbul Low Back Pain Disability Index and Oswestry Disability Index were used. To evaluate depression, Beck's depression scale was used. The diagnosis of metabolic syndrome was made according to the criteria of National Cholesterol Education Program (NCEP) defined in 2001. For this; lumbar circumference around anterior iliac spine, arterial blood pressure, fasting blood glucose, plasma triglyceride levels and HDL cholesterol levels were noted down. Sixty patients (51 women) were included in the study. There was significant difference in terms of BMI (P = 0.034), age (P = 0.001), waist circumference (P = 0.048) and disease duration (P = 0.005) between chronic low back pain patients with and without metabolic syndrome. There was no significant difference in other parameters. Low back pain is a frequent complaint amongst people with obesity in the abdominal area. According to our results, elderly people, people with chronic low back pain and patients with high BMI are under risk for metabolic syndrome. For this reason this group of patients can be screened for metabolic syndrome and preventive measures can be taken.
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    EVALUATION OF SERUM LEVELS OF INTERLEUKIN(IL)-17A, IL-17B, IL-17C, IL-17F AND IL-23 LEVELS IN PSORIATIC ARTHRITIS
    Duruöz, MT; Uçar, Ü; Guvenç, Y; Sürmeli, ZS
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    Autoinflammatory conditions: when to suspect? How to treat?
    Grateau, G; Duruöz, MT
    The term 'autoinflammatory disease' encompasses an enlarging group of inflammatory disorders defined as Mendelian genetic diseases of the innate immune system. This group is growing considering the fact that diseases sharing strong similarities with this core group can be defined as autoinflammatory. The core group consists now of six disorders also known as hereditary recurrent fever syndromes. Thez most common is familial Mediterranean fever, an autosomal recessive disease affecting mainly populations of Mediterranean ancestry. All these six diseases are characterised by inflammatory attacks both at the clinical and at the biological level. The diagnosis of each of these diseases relies first on clinical features and second on genetic testing, which is guided by the clinical results. Deciphering the role of interleukin-1 in the regulation of the inflammatory response through the inflammasome represents a major advance in the knowledge of the mechanisms of these diseases with, as a main consequence, treatment with interleukin-1 inhibitors. (C) 2009 Elsevier Ltd. All rights reserved.
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    Assessment of fatigue in patients with ankylosing spondylitis
    Turan, Y; Duruöz, MT; Bal, S; Guvenc, A; Cerrahoglu, L; Gurgan, A
    In this study, we evaluated fatigue by using the multidimensional assessment of fatigue (MAF) index in 68 ankylosing spondylitis (AS) patients. To determine the disease activity, functional status and quality of life, bath ankylosing spondylitis disease activity index (BASDAI), bath ankylosing spondylitis functional index (BASFI) and Short Form 36 (SF36) were used respectively. Mander enthesis index (MEI) was used for evaluation of enthesitis. The mean age of the patients was 37.7 (11.1) years. The prevalence of fatigue was 76.5%. There were significant correlations between MAF and BASDAI (P < 0.001), BASFI (P < 0.001), MEI (P = 0.048), pain (P = 0.001), hemoglobin (P = 0.001), ESR (P = 0.035), dorsal Schober's (P = 0.009), occiput-wall distance (P = 0.048). Also MAF was correlated with all dimensions of SF36 except for social function and emotional role. BASFI was found to be the most significant correlated (P = 0.002) parameter with MAF. This study suggests that fatigue is an important symptom in AS and it seemed to occur in severe AS patients. It should appropriately be measured with respect to its intensity with appropriate measures, such as MAF. Moreover, fatigue may increase functional disability, which is already present as a feature of the disease.
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    Relationship between enthesitis, clinical parameters and quality of life in spondyloarthritis
    Turan, Y; Duruöz, MT; Cerrahoglu, L
    Objective: To investigate the involvement of enthesis and its correlation with clinical and quality of life parameters inpatients with spondyloarthritis (SpA). Methods: One hundred and eighteen patients who comply with the SpA classification criteria of the European Spondylarthropathy Study Group (ESSG) were included into the study. Clinical parameters such as morning stiffness, rest pain, activity pain, tender joints and swollen joints were evaluated. Enthesitis were assessed by Mander Enthesis Index (MEI). The quality of life was assessed by Short Form-36 (SF-36). Results: The incidence of enthesitis in patient with SpA was found at a rate of 84.9%. There was a significant correlation between MEI and morning stiffness, disease duration, tender joints and six subgroups of SF-36. The hi.-hest correlation was found between MEI and number of tender joint (P < 0.001). Conclusion: Enthesitis is commonly seen among patients with SpA. Enthesitis also affects the life quality of patients negatively. (C) 2009 Societe francaise de rhumatologic. Published by Elsevier Masson SAS. All rights reserved.
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    Assessment of Sleep Quality in Patients with Rheumatoid Arthritis.
    Ucar, U; Duruöz, MT
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    The relation between high cholesterol level and bone mineral density (BMD) in postmenopausal osteoporotic women.
    Cerrahoglu, L; Duruöz, MT; Senocak, I
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    Relation between the Singh's index and the bone mineral density
    Cerrahoglu, L; Duruöz, MT; Tikiz, C; Olcenler, S
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    The relation between dietary calcium intake and bone mineral density in postmenopausal osteoporosis
    Cerrahoglu, L; Duruöz, MT; Tikiz, C; Olcenler, S; Tulukoglu, N
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    EVALUATION OF SLEEP QUALITY IN PSORIATIC ARTHRITIS PATIENTS
    Duruöz, MT; Sürmeli, ZS; Uçar, Ü; Topçu, E; Duruöz, E
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    ADAPTATION AND VALIDATION OF THE OSTEOARTHRITIS KNEE AND HIP QUALITY OF LIFE (OAKHQOL) QUESTIONNAIRE IN TURKISH POPULATION
    Duruöz, MT; Duruöz, E; Uçar, Ü; Topçu, E
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    Validation of Duruoz Hand Index for Diabetic Hand Dysfunction
    Turan, Y; Duruöz, MT; Aksakalli, E; Gürgan, A
    Objectives: Duruoz Hand Index (DHI) is a functional disability scale that can be used successfully to assess the functional disability with different hand arthropathies. The hands are frequently involved in diabetic patients. We aimed to examine the use of DHI for its accuracy and ease in assessing these patients. Methods: Forty patients with diabetes mellitus were recruited in this study Hand pain was assessed with the visual analog scale. Duruoz Hand Index and Hand Functional Index were applied to assess the disability of hand. We evaluated the grip strength and 3 types of pinch strength (tip pinch, lateral or key pinch, and chuck or 3-finger pinch) for the dominant (D) and nondominant (ND) hands of each patient by 2 different kinds of Jamar dynamometers (JA Preston Corp, Jackson, M I). Results: The Jamar dynamometer scores were as follows (mean [SD]): grip strength-D (21.56 [5.86]), grip strength-ND (16.42 [4.26]), tip strength-D (5.14 [1.50]), tip strength-ND (5.13 [1.42]), lateral strength-D (5.15 [1.52]), lateral strength-ND (5.07 [1.19]), chuck strength-D (5.40 (1.40]), chuck strength-ND (5.33 [1.28]). There was a high correlation between DHI and Hand Functional Index (P<0.001, p=0.586)showing that DHI has good convergent validity. The DHI had significant correlation with nonfunctional parameters such as visual analog scale-pain (P < 0.001), restricted hand motion (P = 0.020), chuck strength-D (P = 0.006), pins test-D (P < 0.001), pins test-ND (P = 0.013), and assembly test (P = 0.025). Conclusions: The DHI is a practical scale that is efficient in accurate assessment of hand dysfunction in diabetic patients.
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