Browsing by Author "Ebru Damadoglu"

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    Clinical characteristics of patients requiring lung transplantation referral in national cystic fibrosis registry data
    (2023) Ayşen Bingöl; ERDEM BAŞARAN; Gökçen Dilşa Tuğcu; Sanem Eryilmaz Polat; Abdulhamit Çollak; Selcuk Uzuner; Nihat Sapan; Zeynep Reyhan Onay; Tugba Ramasli Gursoy; Nural Kiper; Nagehan Emiralioglu; Haluk Cezmi cokugras; Sebnem Ozdogan; Pervin Korkmaz; Sukru Cekic; ZEYNEP ÜLKER TAMAY; Azer Kilic Baskan; Mehmet Alp Kose; Ebru Damadoglu; Tugba Sismanlar Eyuboglu; Ayse Tana Aslan; Gonca KILIÇ; NAZAN ÇOBANOGLU; SEVGI PEKCAN; UĞUR ÖZÇELİK; Deniz Dogru; GUZIN CINEL; Ebru Yalcin; Hadice Selimoğlu Şen; velat ŞEN; Gökçen ünal; Asli imran YILMAZ; Ayse Ayzit Kilinc; Hakan Yazan; Ayse Senay Sasihuseyinoglu; Dilek ÖZCAN; Derya Ufuk Altintas; Gökçen Kartal Öztürk; Esen Demir; Ilim Irmak; Ali Özdemir; koray harmancı; Melih Hangul; Hasan Yuksel; Gizem ÖZCAN; erdem topal; Demet Can; Gönül Çaltepe; Mehmet KILIÇ; Erkan CAKIR
    Background. We aimed to determine the number of cystic fibrosis (CF) patients recorded in the Cystic Fibrosis Registry of Türkiye (CFRT) who were in need of lung transplantation (LT) referral and examine clinical differences between patients who were LT candidates due to rapid forced expiratory volume in one second (FEV₁) decline and LT candidates without rapid FEV₁ decline in the last year to identify a preventable cause in patients with such rapid FEV₁ decline. Methods. All CF patients recorded in the CFRT in 2018 were evaluated in terms of LT. Patients were divided into those with FEV₁ below 50% and in need of LT due to a decrease of 20% or more in the previous year (Group 1) and those who did not have FEV₁ decline of more than 20% in the previous year but had other indications for LT (Group 2). Demographic and clinical features were compared between the two groups. Results. Of 1488 patients registered in CFRT, 58 had a need for LT. Twenty patients were included in Group 1 and others in Group 2. Our findings did not reveal any significant variations in treatment, chronic infection status, or complications between the two groups. The average weight z-score was significantly higher in Group 1. Positive correlations were detected between weight z-score and FEV₁ in 2017 in Group 1 and between FEV₁ values in 2017 and 2018 in Group 2. Conclusions. There appears to be a relationship between the nutritional status and weight z-scores of CF patients and pulmonary function, which may indirectly affect the need for lung transplantation referral.
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    Stepwise Approach in Asthma Revisited 2023: Expert Panel Opinion of Turkish Guideline of Asthma Diagnosis and Management Group
    (2023) SEÇIL KEPIL ÖZDEMIR; Gülfem Çelik; omur aydin; Ebru Damadoglu; ayse baccioglu; Sevim Bavbek; Dane Ediger; Ferda Oner Erkekol; Bilun Gemicioglu; Rana Işık; AYSE FÜSUN KALPAKLIOGLU; Ali Fuat Kalyoncu; GÜL KARAKAYA; Metin KEREN; Dilşad Mungan; I.Kivilcim Oguzulgen; Fusun Yildiz; Insu Yilmaz; arzu yorgancıoglu
    Introduction of inhaled corticosteroids (ICS) has been the cornerstone of the long-term management of asthma. ICSs either alone or in combination with long-acting beta-2 agonists have been shown to be associated with favorable asthma outcomes. However, asthma con- trol is still reported to be below expectations all around the world. Research in the last decades focusing on the use of ICS/formoterol both as maintenance and as needed (maintenance and reliever therapy approach) showed improved asthma outcomes. As a result of recent developments, Turkish Asthma Guidelines group aimed to revise asthma treatment recommendations. In general, we recommend physi- cians to consider the risk factors for poor asthma outcomes, patients’ compliance and expectations and then to determine “a personalized treatment plan.” Importantly, the use of short-acting beta-2 agonists alone as a symptom reliever in asthma patients not using regular ICS is no longer recommended. In stepwise treatment approach, we primarily recommend to use ICS-based controllers and initiate ICS as soon as possible. We define 2 different treatment tracks in stepwise approaches as maintenance and reliever therapy or fixed-dose therapy and equally recommend each track depending on the patient’s risks as well as decision of physicians in a personalized manner. For both tracks, a strong recommendation was made in favor of using add-on treatments before initiating phenotype-specific treatment in step 5. A strong recommendation was also made in favor of using biologic agents and/or aspirin treatment after desensitization in severe asthma when indicated.
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    Elderly and aged asthma have different characteristics: results of a multicenter study
    (2024) Ebru Damadoglu; OZGE OZTURK AKTAS; Bilun Gemicioglu; nafiye yılmaz; fulsen bozkus; VEHBİ AYHAN; AYSE FÜSUN KALPAKLIOGLU; Ferda Oner Erkekol; YAVUZ HAVLUCU; FUAT EREL; omur aydin; Aydanur Ekici; ayse baccioglu; SERAP ARGUN BARIS; Gözde Köycü Buhari; Berrin Ceyhan; Ozlem GOKSEL; mehmet köse; Adile Berna Dursun; Fusun Yildiz; arzu yorgancıoglu; Rana Işık; Dane Ediger; I.Kivilcim Oguzulgen; ahmet demir; GÜL KARAKAYA; Ali Fuat Kalyoncu
    Background/ aim: Characteristics of asthma in the elderly population is not well-known. The aim of the present study was to evaluate asthma in the elderly population, to compare disease characteristics between patients diagnosed <60 (aged asthma) and ≥60 (elderly asthma) years of age. Materials and methods: The study was a prospective, multicenter, cross-sectional type. A questionnaire was filled out to patients 60 years of age and over, that have been followed for asthma for at least 3 months. Asthma Control Test (ACT), eight-item Morisky Medication Adherence Scale (MMAS-8) was filled out, inhaler device technique was assessed. Results: A total of 399 patients were included from 17 tertiary care centers across the country. Mean age was 67.11 years and 331 (83%) were female. The age at asthma diagnosis was ≥60 in 146 (36.6%) patients. Patients diagnosed ≥60 years were older (p < 0.001), had higher education level (p < 0.001), more commonly had first-degree relative with asthma (p = 0.038), asthma related comorbidities (p = 0.009) and accompanying rhinitis/rhinosinusitis (p = 0.005), had better asthma control (p = 0.001), were using less controller medications (p = 0.014). Inhaler technique was correct in 37% of the patients with no difference in between the groups. Treatment compliance was better in elderly asthma patients (p < 0.001). In the multivariate logistic regression analysis, having well-controlled asthma (odds ratio = 1.61, CI = 1.04–2.51), and high medication adherence rate (odds ratio = 2.43, CI = 1.48–4.0) were associated with being in the elderly asthma group. Conclusion: The characteristics of asthma are different among patients aged 60 years and over which seems to be related to onset age of asthma. In our cohort, the elderly asthma patients had higher education level, and treatment adherence and asthma control was better. Patients diagnosed ≥60 years of age did not have more severe disease.