Browsing by Author "Eroğlu E."

Now showing 1 - 5 of 5
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    Quantum dots for bioelectrochemical applications
    (wiley, 2019) Polatoğlu I.; Eroğlu E.; Aydın L.
    Electrochemical biosensors based on quantum dots (QDs) have been used for medical, environmental, and food analysis applications due to their unique characteristics, such as high electron transfer ability, large surface area, good interfacial properties, applicability for surface modification, and excellent biocompatibility. All of these characteristics provide signal amplification, selectivity, and reproducibility for electrochemical biosensors. These nanoparticles have been used as electrode modifiers, as active components interacting with the targets, and also as support material for immobilization of recognition elements. Because of their inherent dynamical relation characteristics, mathematical modeling is generally a powerful way to investigate the main effects on the overall bioelectrochemical system (BES) performance. The aim of this chapter is to give brief information about the structure, characteristics, and synthesis of electrochemical sensing properties, bioelectrochemical applications, and finally modeling and optimizations of QDs. © 2020 John Wiley & Sons, Inc.
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    A new generation nanotherapeutic: Phema-chitosan nanocomposites in sirna delivery
    (Bentham Science Publishers, 2020) Eroğlu E.; Portakal H.S.; Pamukçu A.
    Background: Despite great hopes for small interfering RNA (siRNA)-based gene therapies, restrictions, including the presence of nucleases, reticuloendothelial system and undesired electrostatic interactions between nucleic acids and the cell membrane, limit the success of these approaches. In the last few decades, non-viral nucleic acid delivery vectors in nanosize with high biocompatibility, low toxicity and proton sponge effect have emerged as magic bullets to overcome these drawbacks. Objective: This study aimed to develop poly(2-hydroxyethyl methacrylate) (pHEMA)-chitosan nanoparticles (PCNp), and to transfect green fluorescent protein (GFP)-silencing siRNA (GsiR) in vitro. Methods: Firstly, PCNp displaying core-shell structure were synthesized and thereafter GsiR was encapsulated into the core of PCNp. The synthesized PCNp with/without GsiR were characterized using ultraviolet-visible (UV-vis)-spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, thermal decomposition, atomic force microscopy (AFM), scanning electron microscopy (SEM), zeta potential and dynamic light scattering (DLS) measurements. Encapsulation of siRNA into the pHEMA core coated with chitosan shell was demonstrated using fluorescence and FTIR spectroscopy. Results: The surface charges of PCNp and PCNp-GsiR were found to be +39.5 and +40.2, respectively. In DLS analysis, an insignificant shift in the Z-average diameter of PCNp was observed from 109 nm to 133 nm using the encapsulation of GsiR. In comparison to other studied nanomaterials and a commercial transfection reagent, our findings suggest a promising GFP-silencing effect of 45%. Conclusion: To our knowledge, we have obtained comparable silencing activity with the other studied equivalents despite using the lowest concentration of siRNA in existing literature. © 2020 Bentham Science Publishers.
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    Synergistic antimicrobial effects of activated lactoferrin and rosemary extract in vitro and potential application in meat storage
    (Springer, 2020) Soyer F.; Keman D.; Eroğlu E.; Türe H.
    This study aimed to explore the antimicrobial effects of activated lactoferrin (ALF) and rosemary extract (RE) on Escherichia coli O157:H7, Salmonella Enteritidis and Listeria monocytogenes, and to investigate their application potential in the meat storage. Minimum inhibitory concentrations (MICs) of ALF, RE and ALF–RE combinations were determined via microtiter plate assay. MICs of ALF were 1% for E. coli O157:H7; 0.5% for S. Enteritidis and 0.1% for L. monocytogenes. While 15% RE inhibited L. monocytogenes; 30% RE partially inhibited E. coli O157:H7 and S. Enteritidis growth. Synergistic effect of ALF and RE on the inhibition of E. coli O157:H7 increased the activity of ALF two to three folds. Food application of antimicrobials was performed by dipping of meat samples. Both ALF and RE were found effective in the prevention of L. monocytogenes growth about two logs. According to the data, choice of natural antimicrobials may be promising in food preservation. © 2020, Association of Food Scientists & Technologists (India).
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    Triboelectric and Hydrophobic Characterization of Functionalized Lignocellulosic Materials; [Triboelektrična i hidrofobna svojstva funkcionaliziranih lignoceluloznih materijala]
    (University of Zagreb Faculty of Forestry and Wood Technology, 2023) Zor M.; Şen F.; Eroğlu E.; Candan Z.
    In the development of sustainable products, lignocellulosic materials with hydrophobic properties can be functionalized and used as reinforcement, especially in bio-composite materials, as well as in various applications such as packaging, water-repellent and self-renewing materials. This study is aimed to improve the surface properties and triboelectric properties of wood materials. Functionalized wood veneers were prepared by impregnating 3 different wood veneers (beech, mahogany and oak) with 5 different chemical solutions (cationic cellulose, cationic starch, polyethyleneimine, sodium alginate and carboxymethyl cellulose). Structural characterization of the functional wood materials obtained was investigated by Fourier-transform infrared spectroscopy (FT-IR) technique, wettability and surface properties were examined by contact angle measurements, and mor-phological properties were examined by scanning electron microscopy (SEM). The triboelectric properties of the devices prepared using functionalized wood materials were investigated. As a result, it was determined that the hydrophobic properties of wood materials were improved and showed triboelectric properties. It demonstrates that functionalized wood materials can be used to power low-power electronic devices. © 2023 by the author(s). Licensee Faculty of Forestry and Wood Technology, University of Zagreb.
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    Preparation and Characterization of Hydroxyethyl Cellulose/Nanolignin Composite Films
    (North Carolina State University, 2024) Zor M.; Yazici H.; Şen F.; Eroğlu E.; Candan Z.; Rodrigue D.; Wang X.
    Hydroxyethyl cellulose/nanolignin composite films were prepared and characterized. The composite films were produced via casting of synthesized nanolignin added to hydroxyethyl cellulose at different concentrations (2.5%, 5%, 10%, and 20% by mass). A control film without nanolignin was also prepared for comparison. The thermal properties of the composite films were examined by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC), while the mechanical properties were determined by tensile testing and the surface properties were determined by water contact angle measurements. In addition, the morphologies of the samples were examined by scanning electron microscopy (SEM). It was observed that with the addition of nano lignin, the glass transition temperature of the composite films increased from 109 °C to 262 °C; the elongation at break increased from 19% to 51%; and the contact angles increased from 53 °C to 73 °C. The results showed that the presence of nanolignin produced materials being more flexible and more hydrophobic with higher glass transition temperatures. © 2024, North Carolina State University. All rights reserved.