Browsing by Author "Ertay T."

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    Effect of chemotherapy on pulmonary epithelial permeability in lung cancer
    (2000) Sayit E.; Aktoǧu S.; Ertay T.; Çapa G.; Erkmen G.; Özbilek E.; Büyükşirin M.; Durak H.
    The aim of this study is to investigate the effect of one-course chemotherapy on the pulmonary epithelial permeability. Eighteen patients (18 male; mean age: 59 ± 10 years) with lung cancer (11 non-small cell, 7 small cell) inhaled 40 mCi (1,480 MBq) 99mTc-diethylenetriaminepentaacetic acid (DTPA). Thirty images of 1-min duration were acquired from posterior projection. The first 7 min of the decay-corrected time activity curves were used to calculate lung clearance half-time. Clearance half-times of 99mTc-DTPA from the peripheral regions of the lungs were 42 ± 19 min before and 56 ± 34 min after chemotherapy (p = 0.009); from the central regions, clearance half-times were 112 ± 94 min before and 160 ± 125 min after chemotherapy (p = 0.005). This decrease in clearance rate might be related to decreasing mucociliary clearance rate due to the toxic effect of the chemotherapy regimen on cilia movement and/or mucus structure. 99mTc-DTPA radioaerosol study can be used to monitor the toxic effects of chemotherapy on the pulmonary epithelium and possibly on mucociliary function. (C) 2000 Elsevier Science Inc.
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    An integrated fuzzy approach for determining engineering characteristics in concrete industry
    (Bellwether Publishing, Ltd., 2011) Ertay T.; Akyol D.E.; Araz C.
    This paper deals with the modeling of conceptual knowledge to capture the major customer requirements effectively and to transform these requirements systematically into the relevant design requirements. Quality Function Deployment (QFD) is a well-known planning and problem-solving tool for translating customer needs (CNs) into the engineering characteristics (ECs) and can be employed for this modeling. In this study, an integrated methodology is presented to rank ECs for implementing QFD in a fuzzy environment. The proposed methodology uses fuzzy weighted average method as a fuzzy group decision making approach to fuse multiple preference rankings for determining the weights of the customer needs. It adopts a fuzzy Analytic Network Process (ANP) approach which enables the consideration of inner dependencies in a cluster as well as the interdependencies between the clusters to determine the importance of ECs. The proposed approach is illustrated through a case study in ready-mixed concrete industry. Copyright © 2011 Taylor & Francis Group, LLC.