Browsing by Author "Eser, E"
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Item Quality of Life in Patients with Idiopathic Intracranial Hypertension and the Impact of the COVID-19 PandemicÇelebisoy, N; Ak, AK; Özdemir, HN; Gökçay, F; Eser, EThe COVID-19 pandemic became a challenge to maintain care for patients with idiopathic intracranial hypertension (IIH). We aimed to find out how they were affected during lockdown. Thirty IIH patients admitted to hospital during the COVID-19 pandemic were studied. Their demographic and neuro-ophthalmological findings were evaluated. The World Health Organization - Five Well-Being Index (WHO-5), the EUROHIS Quality of Life (QOL) 8-item index, National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25), Headache Impact Test (HIT-6), and COVID-19 Fear Scale were used to assess QOL and pandemic-associated fear. Thirty age, sex, and body mass index matched volunteers constituted the control group. Apart from the COVID-19 Fear Scale and colour vision subscale of the NEI-VFQ-25, all scale scores were worse in IIH patients than in healthy control subjects. Patients with severe visual field defects had higher HIT-6 scores (p = .036). Both vision-specific and overall QOL was reduced in patients with IIH. Headache severity and disability were more prominent in patients with severe visual loss. Fear caused by the COVID pandemic was not different in IIH patients than in healthy control subjects.Item Caregiver Burden and associated risk factors in relatives of patients with obsessive compulsive disorderDikici, DS; Eser, E; Cökmüs, FP; Demet, MMItem VALIDITY AND RELIABILITY OF THE TURKISH VERSION OF 'AACHEN FALLS PREVENTION SCALE' IN OLDER INDIVIDUALSÖztürk, ZÖ; Eser, E; Ilgün, MIntroduction: This study aimed to develop a Turkish version of the Aachen Falls Prevention Scale and determine its psychometric properties (reliability and validity). Materials and Method: This methodological study involved 200 individuals aged >= 65 years from selected Family Health Centers in Manisa, Turkey, who were categorised as fallers and non-fallers. The study proceeded with distribution and item analyses of the scale, followed by reliability and validity assessments, including criterion validity, confirmatory factor analysis, known groups, and parallel form validity for construct validity. Results:The Turkish version of Aachen Falls Prevention Scale demonstrated a sensitivity of 71.0% and specificity of 75.0% for the first part of the index score and a sensitivity of 75.0% and specificity of 55.0%forthe third part. Confirmatory factor analysis for the single-factor structure of the first section yielded a chisquare/degrees of freedom ratio of 1.13, a comparative fit index of 0.939, and a root mean square error of approximation of 0.025. According to the results of known-groups analysis, the 1st and the 3rd parts of the scale were discriminative for all known groups whereas the 2nd part was not sensitive to some variables. Conclusion: The study findings indicate highly satisfactory psychometric results for the Aachen Falls Prevention Scale. Specifically, the tool showed superior predictive capabilityforfall risk in older individuals compared to balance tests, such as the Tinetti test. Consequently, the Aachen Falls Prevention Scale can effectively assess fall risk among Turkish-speaking older adults in hospitals and primary healthcare settings.Item QUALITY-OF-LIFE ASSESSMENT OF APPLIED THERAPY TO BREAST CANCER PATIENTSSert, F; Özsaran, Z; Eser, E; Alanyali, S; Haydaroglu, A; Aras, AObjective: Quality-of-Life (QoL) has an important role for breast cancer patients when considering long life expectancy. The main purpose of this study is evaluating the impact of hormonal therapy upon QoL, which is applied after radiotherapy, in the light of realistic data. Materials and Methods: The breast cancer patients treated with adjuvant radiotherapy at Ege University Hospital between January 2007 and December 2009 were evaluated for this trial after obtaining their informed consent FACT-Gv4 and FACT-ESv4 FACT-ES questionnaires were used for QoL evaluations. Obtained surveys were evaluated with the original guide of FACT. Results: A body mass index of over 30 was used as the obesity limit. There was a statistical significance between social well-being score and obesity (p=0.028). Functional well-being scores were statistically better for the patients without co-morbid disease (p=0.018). Endocrine subscale scores were deteriorated during hormonal therapy but they presented some increase in second evaluation but they did not reach basal levels (p=0.000 for all parameters). Conclusion: The diagnosis of breast cancer is affecting QoL independently of the applied treatment. When considering this, post-diagnosis and/or pretreatment physiological support is very important. Methods of treatment and the patient's demographic data are important factors that may affect the QoL. Assessment of QoL has an important role in terms of patient compliance to disease and treatment. For breast cancer patients who have a long life expectancy, multi-institutional QoL researches are needed for presenting the patient's beliefs and adherences to their therapy. We can provide more detailed and clear information with the help of future researches.Item Protective effects of amifostine on radiation-induced damage of testis tissue: an experimental animal studyAndrieu, MN; Kurtman, C; Hicsonmez, A; Ozbilgin, K; Eser, EItem Validity and reliability analysis of the Turkish version of pediatric nutritional risk score scaleTasci, O; Soylu, ÖB; Tasci, EK; Eser, E; Oruçoglu, B; Günay, IBackground/Aims: We aimed to perform the validity and reliability analysis of the Turkish version of the Pediatric Nutritional Risk Score (PNRS). Materials and Methods: The study group consisted of 149 patients aged between 1 month and 18 years who were admitted to the hospital for at least 48 h. The patients' age, gender, anthropometric measurements, length of stay, admission diagnosis, daily body weights, food consumption, and pain status were recorded. Backward and forward translations into Turkish were done. PNRS was performed by two different physicians. The consistency of the PNRS results was evaluated to determine the validity of PNRS. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. Results: Of all patients, 69 (46.3%) were female and 80 (53.7%) were male. The mean length of the stay was 7.3 +/- 4.0 days. The mean age of the patients was 51.9 +/- 63.6 months. The Kappa coefficient between the two physicians was 0.66. Weight loss was observed in 65.2% of the patients in the high-risk group and 25.4% in the low-risk group. The hospital malnutrition rate was 31.5%. A higher risk was identified in those with <50% food intake and more severe disease. The specificity, sensitivity, NPV, and PPV of PNRS were 82.1%, 77.8%, 92.0%, and 58.3%, respectively. Conclusion: A good consistency suggests that the Turkish validation was achieved successfully. The power of PNRS to discriminate the patients with moderate-low risk of developing malnutrition is higher than the patients with high risk. PNRS is considered a valid and reliable tool to establish the risk of malnutrition in the hospitalized patients.Item TESTING THE PSYCHOMETRIC PROPERTIES OF THE TURKISH VERSION OF THE KINDL-R GENERIC HRQOL MEASURE FOR CHILDRENEser, E; Yuksel, H; Baydur, H; Erhart, M; Saatli, G; Ozyurt, BC; Ravens-Sieberer, UItem Comparing the Quality of Life of Patients With Hemophilia and Juvenile Idiopathic Arthritis in Which Chronic Arthropathy Is a Common ComplicationOymak, Y; Kaygusuz, A; Turedi, A; Yaman, Y; Eser, E; Cubukcu, D; Vergin, CIntroduction: Hemophilia is a genetic disorder in which recurrent joint bleeding causes arthropathy. Inflammation and degeneration play roles in the pathogenesis of hemophilic arthropathy. Patients with juvenile idiopathic arthritis (JIA) experience a similar inflammatory degenerative joint disease. A comparison of different patients with common pathogenetic features may identify unique features helpful in terms of the follow-up. Aim: We compared the quality of life (QoL) of patients with hemophilia and JIA, and healthy controls, using a generic QoL scale, Kidscreen and Disabkids Questionnaires (KINDL). Differences among groups were evaluated in terms of sociodemographic characteristics and clinical parameters affecting the QoL. Methods: We included 33 hemophilia patients, 19 JIA patients, and 32 healthy individuals aged 4 to 18 years. Sociodemographic characteristics (the age, the maternal educational status, the place of residence, the size of the household, the household income, divorced parents) were noted, and the KINDL was administered to all participants. Clinical parameters associated with arthropathy (the functional independence score [FISH], the hemophilia joint health score [HJHS], the arthropathic joint count, and the painful joint count) were documented. Differences in frequencies and medians among the groups were evaluated using the (2), the Mann-Whitney U, and the Kruskal-Wallis tests. Results: All KINDL dimensions were above 50, reflecting good conditions in the 2 patient groups. No difference between patients with hemophilia and JIA was evident in terms of the clinical parameters of FISH, the HJHS, or the arthropathic or painful joint counts (P>0.05). Sociodemographically, only the frequency of literate mothers was lower in patients with hemophilia than in those with JIA and healthy controls (P=0.03). Patients with JIA scored more higher on the KINDL dimension of chronic illness than those with hemophilia (P=0.02). The FISH score correlated with the total QoL score in both patients with hemophilia and JIA (r=0.39, P=0.03 and r=0.48, P=0.04, respectively). Conclusions: Although no difference was evident between the patient groups in terms of clinical parameters associated with arthropathy, JIA patients coped better with illness than those with hemophilia. JIA patients had a higher proportion of literate mothers than hemophilia patients; this may affect a patient's ability to cope with issues relating to chronic illness. Implementation of an educational program for mothers of hemophilia patients, during follow-up, may improve the patient's QoL. Also, hemophilia patients should be assisted to improve their QoL in the dimensions of self-esteem and schooling. Lastly, the evaluation of functional disability by FISH in hemophilia patients is important because the FISH score correlated with the total QoL score, as revealed by KINDL. In JIA patients also, functional disabilities caused by arthropathy affected the QoL.Item The Turkish Validity and Reliability of the Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms ScalesKutlu, A; Yilmaz, E; Çeçen, D; Eser, E; Özbakkaloglu, AThe aim of the study was to test Turkish validity and reliability of Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms (VEINES-QoL/Sym) in patients with chronic venous insufficiency (CVI). A total of 118 patients with CVI hospitalized in 3 different hospitals were enrolled in this study. VEINES-QoL/Sym, translated to Turkish with a standard methodology, was applied to the patients and was evaluated for acceptability, reliability, validity, and responsiveness. Cronbach alpha (including if item deleted) values were used for the reliability analysis. Construct and criterion validity approaches were used for validity analysis. Cronbach alpha values are .86 for the VEINES-QOL and .81 for the VEINES-Sym. No problematic items were observed for the scale. The VEINES-QoL/Sym was significantly sensitive to clinical, etiology, anatomy, and pathophysiology (CEAP) classification, indicating good criterion validity. Significant correlation was found between scores of SF-36 and VEINES-QoL (r = .43-.66). Turkish version of the VEINES-QOL/Sym was found reliable and valid for Turkish patients with CVI.Item Monitoring the Quality of Life in Dyspeptic Children with KINDL ScaleTasci, EK; Soylu, ÖB; Tasci, O; Günay, I; Eser, EAim: We aimed to evaluate quality of life in functional and organic dyspepsia and its change during follow-up. Materials and Methods: Children between 4-17 years of age with dyspeptic complaints were enrolled into this study. Organic and functional dyspepsia were differentiated based on clinical findings and the findings of upper gastrointestinal endoscopy, if performed. The Kinder Lebensqualitat Fragebogen (KINDL) questionnaire was conducted when the patients were referred to hospital and at their 1st and 3rd month visits, prospectively. Both groups were compared with regard to their demographic data, symptoms and quality of life scores. Factors which affected the KINDL results and any changes in the KINDL scores during follow-up were evaluated. Results: The study group consisted of 71 functional dyspepsia and 65 organic dyspepsia patients. The mean quality of life scores in the physical wellness and school subscales were higher among the functional dyspepsia patients. The total score of the functional dyspepsia group was higher. There was no relation between the individual's gender, their number of symptoms and their KINDL scores. At the first month visit, the total scores and mean scores of the self-esteem, family, school and friends subscales were higher in the functional dyspepsia group. At the third month visit, the mean self-esteem score was higher in the functional dyspepsia group. Total scores increased significantly during follow-up in both the organic dyspepsia and functional dyspepsia groups. This increase was higher in the organic dyspepsia group. Conclusion: Quality of life in both functional dyspepsia and organic dyspepsia patients is affected; applying recommendations and treatment increased the quality of life of both groups. A quality of life scale can be used to monitor response to treatment.Item The Psychometric Properties of the New Turkish Generic Health-Related Quality of Life Questionnaire for Children (Kid-KINDL)Eser, E; Yüksel, H; Baydur, H; Erhart, M; Saatli, G; Özyurt, BC; Özcan, C; Ravens-Sieberer, UObjective: There are few health-related quality of life (HRQOL) instruments available that have been validated for use with Turkish children, The Kid-KINDL is a generic measure of children's (8-12 years) HRQOL, which contains 24 categorical items that assess 6 dimensions (physical well-being, emotional well-being, self-esteem, family, friends, and school). The Kid-KINDL is available in many languages. Following on elaborate translation procedure and cognitive focus group interviews, the Kid-KINDL was adopted into Turkish. This paper describes the psychometric properties of the new Turkish Kid-KINDL. Methods: In total, 1918 children aged 8-12 years at a school in Manisa completed the Kid-KINDL. A confirmatory approach was used for validity and reliability analysis. Using the Multi-trait/Multi-item analysis program (MAP) item-internal consistency and item-discriminant validity were calculated to confirm the instrument's structure. Likert scaling assumptions were tested and confirmatory factor analysis (CIA) was applied as well. After modification of 2 unsatisfactory items the Kid-KINDL was administered to a different group of 84 randomly selected children and the analyses were repeated. Results: Cronbach's alpha was 0.35-0.78 before and 0.54-0.78 after the scales was modified. MAP-scaling success was 60%-100% before and 90%-100% after the modification. CIA confirmed the Kid-KINDL structure for the original version (RMSEA = 0.077) was less than the modified version (RMSEA = 0.059), although for the latter the sample was rather small, Floor effects were negligible, and ceiling effects reached 19%. Conclusion: The results indicate that the Turkish Kid-KINDL was a reliable and factorially valid assessment of the children's HRQOL. The modifications mode to the 2 unsatisfactory items increased the psychometric quality of the scale.Item Reliability and validity of the Turkish version of the Chronic Heart Failure QuestionnaireYilmaz, E; Eser, E; Gürgün, C; Kültürsay, HObjective: Any disease specific Health Related Quality of Life Instrument for Chronic Heart Failure (CHF) is lacking in Turkey. The aim of this study is to adapt the Chronic Heart Failure Questionnaire (CHQ) into Turkish and probe the reliability and validity of this questionnaire. Methods: There are four dimensions of this 20 items scale. These dimensions are: dyspnea (5 items), fatigue (4 items), emotional status (7 items) and mastery (4 items). Response options were evaluated using a 7 -point Liken type scale. Quality of life (QOL) improves as the score increases. A total of 205 CHF patients hospitalized in the Department of Cardiology of Ege University hospital were enrolled in this study. The CHQ was applied to the patients twice with a wash-out period of 15 days. Confirmatory approach was used during the reliability and validity analysis. Cronbach alpha test was used for the reliability analysis. Confirmatory factor analysis (CFA) was used for the construct validity testing. NYHA classification for testing the criterion validity; SF-36 and WHOQOL-100 General Health and QOL facet for convergent validity testing of the Turkish version of the CHQ were used. Responsiveness to change was evaluated by Effect Size analysis by using test-retest data. Results: The range of Cronbach alpha values is 0.72-0.94. A considerable ceiling and floor effects were observed for the dyspnea dimension of the scale but no problematic items were observed for the entire scale. The CFA results supported the original four factors scale structure. Criterion and construct validity rebuts were satisfactory. Effect sizes obtained among dimensions of the CHQ were between 0.13 and 0.56. Conclusion: Overall results revealed that Turkish version of the CHQ is a reliable and valid instrument to be used for the evaluation of CHF patients. (Anadolu Kardiyol Derg 2010; 10: 526-38)Item Validity and reliability of the Turkish version of the knowledge about childhood autism among health workers questionnaireÖzgür, BG; Aksu, H; Eser, EObjective: The aim of this study is to present the psychometric properties of the Turkish version of the knowledge about childhood autism among health workers (KCAHW) questionnaire. Methods: Three hundred fifteen primary health care facility workers and 28 child and adolescent mental health professionals were enrolled in this study. Participants filled out socio-demographic data forms and the KCAHW. Reliability analyses consisted of internal consistency and test-retest reliability. For validity analysis, construct validity (confirmatory factor analysis -CFA) and criterion validity were used. Results: The mean KCAHW questionnaire score was 13.83 +/- 2.55. The floor effects in all domains were below 15%, the ceiling effects were over 15% in overall score and in Domain 4. Intraclass correlation coefficient and the Kuder Richardson 21 values were 0.83 and 0.683, respectively; All goodness of fit indices generated by CFA were found satisfactory (Comparative fit index = 0.79; Root mean square error of approximation = 0.056, and chi-square/degree of freedom = 1.91). Being a physician, being a CAMH specialist, having mental health clinic experience, having done a child psychiatry internship, knowing someone diagnosed with autism, follow-up experience of a patient with autism, having previous autism training, and the perception of adequate knowledge about autism, significantly increased the KCAHW scores (p < 0.001). Conclusion: The Turkish version of the KCAHW questionnaire is reliable (in terms of test-retest and internal consistency) and valid (sensitive some known/expected external criteria). Due to the insufficient internal consistency in Domain 4, the scores received from Domain 4 should be evaluated with caution.Item CAN URINARY BIOMARKERS SUCCEED DIAGNOSTIC VALUE OF RENAL SCINTIGRAPHY IN PATIENTS WITH URETEROPELVIC JUNCTION DISRUPTION?Gürer, DE; Yilmaz, Ö; Ertan, P; Eser, E; Taneli, F; Aras, F; Oran, A; Genç, A; Günsar, C; Sencan, A; Gürer, E; Taneli, CItem The Reliability and Validity of the Turkish Version of the Constipation Risk Assessment ScaleKutlu, AK; Yilmaz, E; Çeçen, D; Eser, EThe aim of this study is to translate into the Turkish language, and test the reliability and validity, of the Turkish version of the Constipation Risk Assessment Scale (CRAS). This study consisted of 245 adult in-patients who were hospitalized in the medical and surgical clinics of Celal Bayar University Hospital in January through May 2007. The patients were categorized into two groups (constipated and not constipated) according to Rome II criteria. All participants were assessed with the CRAS. The CRAS was retested on 32 patients selected randomly from among the initial constipated group (n = 152). The statistical analysis consisted of reliability and validity analyses. Test-retest comparison and internal consistency were used to assess the reliability of the instrument. Divergence and known groups approaches were used to test for construct validity. Correlation analysis using the Pearson's coefficient was conducted to assess the test-retest. For testing of the criteria and known groups, Student's t test and Mann-Whitney U test were used. Cronbach's alpha value for the constipated respondents was r = 61.9. According to the effect size comparisons, the most effective variable on the CRAS score was perception of constipation risk requirement. The overall score and subsection score correlations were also found acceptable (r = 0.47-0.57).Item Psychometric Properties of the Turkish Version of the Epilepsy Module of the KINDL Quality of Life ScaleErgin, D; Demirbag, S; Eser, E; Polat, M; Baydur, HIntroduction: This study aims to present the psychometric properties of the Turkish version of the KINDLE quality of life scale, epilepsy module. Method: The psychometric properties of the KINDL Epilepsy module were evaluated from the aspect of internal consistency, reliability, and construct validity on an inpatient sample of 159 Turkish children (mean age 10.84 +/- 2.77 years) who had epilepsy. Results: The KINDL Epilepsy module (36 items) showed acceptable a coefficients ranging from 0.80 (social well-being) to 0.55 (treatment) for each domain. EFA suggested three sub-dimensions that we named as Physical, Mental and Social Well-being sub-dimensions. Root Mean Square Error of Approximation was found as 0.053, and Comparative Fit Index was 0.95. Good known groups results supported the construct validity of the instrument. Correlations between the income perception, family support and Duration of Epilepsy and the domains of its Epilepsy module were significantly high, indicating a satisfactory convergent validity. Conclusion: The Turkish version of the KINDL Epilepsy module showed module is a promising tool in this study. However, further research on the versions of the module in other languages is needed for its global use.Item The relationship between obesity and health related quality of life of women in a Turkish city with a high prevalence of obesityDinç, G; Eser, E; Saatli, G; Cihan, ÜA; Oral, A; Baydur, H; Özcan, CThe purpose of this study was to demonstrate the relationship between body weight and HRQOL in a representative sample of nonpregnant women in reproductive age period. The data of this cross-sectional study was extracted from a survey: Manisa Demographic and Health Survey (MDHS) conducted in Manisa city in 2000. The study population of MDHS is a representative sample of 1602 reproductive (15-49) age women. World Health Organization Quality of Life Questionnaire abbreviated version (WHOQOL-BREF), which was composed of four domain factors (physical, psychological, social relations and the environment), was used to assess HRQOL. Each of four domains had a possible score ranged between 0 (poor HRQOL) and 20 (excellent HRQOL). The mean age of the women was 35.29 +/- 8.19 years. Among them, 35.8 % had normal weight (BMI 18.5 to 24.9), 32.3 % were overweight (BMI 25.0 to 29.9) while 31.9 % were moderate and 3.4% were morbidly obese. After adjusting for age, level of education and co-morbid illnesses, subjects with a BMI higher than normal value, had significantly lower HRQOL scores, compared to normal-weight individuals on each of the domains, except for the environmental domain. Our results suggested that the body weight alone could negatively affect HRQOL. In other words, obesity not only increased the risk of morbidity and mortality, but also affected the perceived health and life quality negatively. In conclusion, in addition to age, socioeconomic status and co-morbid illnesses, body weight should also be controlled in studies examining HRQOL.Item NORMATIVE AND PSYCHOMETRIC PROPERTIES OF THE WHOQOL OLDER ADULTS MODULE (WHOQOL-OLD) IN THE NATIONAL REPOSITORYEser, E; Sahin, BB; Eser, SIntroduction: The main objectives of this study were to present population norms and the construct validity of the WHOQOL-OLD using classical and modern (Rasch) psychometric analyses.Methods: This study was conducted on the pooled data of 29 studies, 16 of which were representative of the population (n=6951). The psychometric properties of the WHOQOL-OLD were evaluated with classical (confirmatory factor analysis and multivariate regression model) and probabilistic test theory (Rasch and DIF) analyses. Results: The mean age of the Turkish WHOQOL-OLD data pool was 73.2 +/- 6.8. The mean overall scale score was 81.27 +/- 13.57 and the range of the mean dimension scores was between 12.34 (social participation) and 14.59 (intimacy). The elderly (advanced age) and women are more sensitive to the decrease in quality-of-life (QoL) scores. Both Cronbach's alpha values and item analyses indicated good internal consistency for all dimensions. Exploratory factor analyses (EFA) generated five factors instead of a six-factor original scale structure. Past, present, and future activities and social participation were combined in a single dimension in the EFA. Confirmatory factor analyses resulted in acceptable goodness of fit indices, such as Confirmation Fit Index (CFI)=0.951 and Root Mean Square Error of Approximation (RMSEA)=0.055. Turkish elders perceive the death and dying dimension as culturally closer to the culture of developing countries than developed Western cultures. Conclusion: Turkish older adults' QoL scores were more or less like those of other older adults in developing countries. This study's results confirm that the acceptable psychometric properties of the WHOQOL-OLD-TR with some items (items 9 and 20) need to be worked on further.