Browsing by Author "Evren, Vedat"

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    Electrical analogue of arterial blood pressure signals
    (Gümüşhane Üniversitesi, 2018) Emek, Sevcan; Evren, Vedat; Bora, Şebnem; Emek, Sevcan; Fakülteler > Mühendislik Ve Doğa Bilimleri Fakültesi > Bilgisayar Mühendisliği Bölümü
    In this study, we propose an electrical circuit model that will be useful for understanding of the mechanisms and dynamics of the human cardiovascular system, which is considered as a complex system in the field of physiology. The electrical circuit model, defined as the Windkessel model, plays an important role in the observation of the characteristic effect of the blood pressure on the arterial system. An electrical circuit model, which we have connected to the input terminals of the Windkessel model, ensures that the mean arterial blood pressure signals are observed within the expected range of values. The Windkessel circuit model that we have tried to develop in this study was constructed in a laboratory environment and the results were observed. It is thought that this study will contribute to the literature in terms of the development of the Windkessel model by increasing the number of parameters involved in the models of heart and arterial system.
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    Simulation of glucose regulating mechanism with an agent-based software engineering tool
    (Balikesir University, 2019) Emek, Sevcan; Evren, Vedat; Bora, Şebnem; Emek, Sevcan; Fakülteler > Mühendislik Ve Doğa Bilimleri Fakültesi > Bilgisayar Mühendisliği Bölümü
    This study provides a detailed explanation of a regulating mechanism of the blood glucose levels by an agent-based software engineering tool. Repast Simphony which is used in implementation of this study is an agent-based software engineering tool based on the object-oriented programming using Java language. Agent-based modeling and simulation is a computational methodology for simulating and exploring phenomena that includes a large set of active components represented by agents. The agents are main components situated in space and time of agent-based simulation environment. In this study, we present hormonal regulation of blood glucose levels by our improved agent-based control mechanism. Hormonal regulation of blood glucose levels is an important process to maintain homeostasis inside the human body. We offer a negative feedback control mechanism with agent-based modeling approach to regulate the secretion of insulin hormone which is responsible for increasing the blood glucose levels. The negative feedback control mechanism run by three main agents that interact with each other to perform their local actions in the simulation environment. The result of this study shows the local behavior of the agents in the negative feedback loop and illustrates how to balance the blood glucose levels. Finally, this study which is thought a potential implementation of agent-based modeling and simulation may contribute to the exploration of other homeostatic control systems inside the human body.