Browsing by Author "Fistik T."

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Evaluation of non-invasive clinical samples in chronic Chlamydial prostatitis by using In situ hybridization
    (Informa Healthcare, 1997) Gümüş B.; Sengil A.Z.; Solak M.; Fistik T.; Alibey E.; Çakmak E.A.; Yeter M.
    Seventy-eight non-invasive prostate specimens collected from patients with chronic non-bacterial prostatitis were evaluated by in situ hybridization (IH) for evidence of Chlamydia trachomatis. Intracellular Chlamydia bodies were detected in 18 of 78 cases (20.6%). Homogeneous blue- black bodies in the cellular cytoplasm were accepted as in situ positive. Chlamydial antigen detected by enzyme immuno assay (EIA) was positive in 12 cases (13.7%), but only nine of them were positive by IH. Our study confirms previous reports implicating C. trachomatis as an aetiological agent in chronic non-bacterial prostatitis, and underscores the applicability of DNA probes for detection and identification of C. trachomatis in prostatic materials.
  • No Thumbnail Available
    Item
    Effects of sevoflurane on the cell division and levels of sister cromatid exchange; [Sevofluran hucre bolunmesi ve kardes kromatid degisimi duzeyleri uzerine etkisi]
    (1999) Solak M.; Erincler T.; Luleci E.; Gul R.; Luleci N.; Fistik T.; Tutan A.
    In this study, the mitotic index (MI) and Sister Cromatid Exchange (SCE) levels were investigated to identify the mutagenic and carcinogenic effects of sevoflurane (sevorane). The data of 20 patients in ASA I-II were studied. All of the patients received an anaesthesia induction with anaesthesia mask and 'tidal volume method. 8 % sevoflurane in 100 % oksigen was used to the induction of anaesthesia and 0.1 mg/kg vecuronium for neuromuscular block and intratracheal intubation. Anaesthesia continued with 2-2.5 sevoflurane, in 60 % N2O and 40 % O2 . Three mL venous blood samples taken before (as controls) 60 minutes, 24 hours and 5 days after the sevoflurane induction, were examined according to the periferic blood culture assay with conventional cytogenetic methods. On the metaphase plaques which obtained in this way, the levels of MI and SCE were examined. As a result, a significant decrease of MI has been found in the test objects at the first 60 minutes of sevoflurane anaesthesia compared to controls (p<0.001). But this depression was smaller after 24 hours (p<0.01) and reversible after 5 days (p>0.05). SCE increased significantly at the first 60 minutes of anaesthesia (p<0.001) was also smaller after 24 hours (p<0.01) and returned to normal levels after 5 days (p>0.05). As conclusion; It has been revealed the effects of sevoflurane on cellular replication and on DNA at the cellular level were repaired in a short period of time. Thus, it has been suggested that sevoflurane had no permanent effect on genetic material of healthy individuals.
  • No Thumbnail Available
    Item
    Analysis of the dermatoglyphics in Turkish patients with Klinefelter's syndrome
    (2008) Sirri Cam F.; Gul D.; Tunca Y.; Fistik T.; Ozdemir Erdogan M.; Yildiz H.; Erdem S.; Solak M.
    The word "dermatoglyphics" indicates study of epidermal ridge configuration on palms, soles and fingertips. This investigation was aimed to analyze dermatoglyphic patterns in Klinefelter's syndrome (KS) patients. The study cohort consisted of 57 cases and 25 controls. The prints were taken by using the ink method. Fingertip patterns, triradial counts, a-t-d angle and a-b ridge count were studied. There were significant differences in radial loops and whorls (p < 0.05), and there were very highly significant differences in arches (p < 0.001) in KS patients as compared to controls. Dermatoglyphic patterns at the hypothenar area (p < 0.05), and areas between at the I. interdigital and thenar sites (p < 0.001) have been found to be significantly different in KS patients compared to controls. Total ridge counts (TRC), a-b, a-t-d angels were not different in the two groups (p > 0.05). A definite correlation between the dermatoglyphic patterns and the KS has been shown. © Journal compilation © 2008 Hereditas.