Browsing by Author "Gökçe S."

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    Familial mediterranean fever mutation analysis in pediatric patients with İnflammatory Bowel Disease: A multicenter study
    (AVES, 2021) Urganci N.; Ozgenc F.; Kuloǧlu Z.; Yüksekkaya H.; Sari S.; Erkan T.; Önal Z.; Çaltepe G.; Akçam M.; Arslan D.; Arslan N.; Artan R.; Aydoǧan A.; Balamtekin N.; Baran M.; Baysoy G.; Çakir M.; Dalgiç B.; Doǧan Y.; Durmaz O.; Ecevit C.; Eren M.; Gökçe S.; Gülerman F.; Gürakan F.; Hizli S.; Işik I.; Kalayci A.G.; Kansu A.; Kutlu T.; Karabiber H.; Kasirga E.; Kutluk G.; Hoşnut F.O.; Özen H.; Özkan T.; Öztürk Y.; Soylu O.B.; Tutar E.; Tümgör G.; Ünal F.; Ugraş M.; Üstündaǧ G.; Yaman A.
    Background: The aim of the study was to evaluate familial Mediterranean fever (FMF) mutation analysis in pediatric patients with inflammatory bowel disease (IBD). The relation between MEFV mutations and chronic inflammatory diseases has been reported previously. Methods: Children with IBD (334 ulcerative colitis (UC), 224 Crohn's disease (CD), 39 indeterminate colitis (IC)) were tested for FMF mutations in this multicenter study. The distribution of mutations according to disease type, histopathological findings, and disease activity indexes was determined. Results: A total of 597 children (mean age: 10.8 ± 4.6 years, M/F: 1.05) with IBD were included in the study. In this study, 41.9% of the patients had FMF mutations. E148Q was the most common mutation in UC and CD, and M694V in IC (30.5%, 34.5%, 47.1%, respectively). There was a significant difference in terms of endoscopic and histopathological findings according to mutation types (homozygous/ heterozygous) in patients with UC (P < .05). There was a statistically significant difference between colonoscopy findings in patients with or without mutations (P = .031, P = .045, respectively). The patients with UC who had mutations had lower Pediatric Ulcerative Colitis Activity Index (PUCAI) scores than the patients without mutations (P = .007). Conclusion: Although FMF mutations are unrelated to CD patients, but observed in UC patients with low PUCAI scores, it was established that mutations do not have a high impact on inflammatory response and clinical outcome of the disease. Copyright © 2021 by The Turkish Society of Gastroenterology.
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    Kinetic parameters and luminescence properties of rare earth (Tb, Nd) doped and transition metal (Mn) doped/co-doped YAlO3 prepared via sol-gel method
    (Elsevier B.V., 2023) Gökçe S.; Keskin İ.Ç.; Katı M.İ.; Kibar R.; Çetin A.; Tuncer Arslanlar Y.
    In this work, phosphor materials with the formula YAlO3 were synthesized via sol-gel method by using the stoichiometric amounts of yttrium nitrate and aluminum nitrate as base materials. The obtained phosphors were doped/co-doped with Tb3+, Nd3+ rare earth ions and Mn2+ transition metal ion. For evaluating the influence of the dopants, the grain size and morphology of the samples by scanning electron microscopy (SEM) and the phase and crystallinity of the synthesized materials by X-ray diffraction (XRD) were investigated. Optical absorption spectra, photoluminescence (PL) and thermoluminescence (TL) were performed to determine a relationship the changing dopant on luminescence properties of YAlO3. Moreover, the kinetic parameters namely activation energy (E), order of kinetics (b) and frequency factor (s) of the synthesized pure and doped materials were calculated using Computerized Glow Curve Deconvolution (CGCD) and Peak Shape Method for a better understanding of the optical properties that change with the doping process. Strong green emission was detected in the sample doped with Mn2+ correspond to 4T1(G)→6A1(S) transition. As for YAlO3: Nd3+, characteristic emissions originated from 4G11/2 → 4I9/2 (∼423 nm), 4G9/2 → 4I9/2 (∼460 nm) and 4G7/2 → 4I9/2 (∼540 nm) transitions were seen. The optical band gap of undoped sample was calculated as 2.79 eV and depending on the presence of Nd3+ and Tb3+ dopant ions this value was decreased to the range 2.46–2.56 eV. © 2023 Elsevier B.V.
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    Luminescence characteristics and kinetic parameters of LiBaPO4: Tb3+, Dy3+ phosphors synthesized by sol-gel method
    (Elsevier B.V., 2024) Katı M.İ.; Gökçe S.; Keskin İ.Ç.; Türemiş M.; Çetin A.; Kibar R.
    LiBaPO4: Tb3+, Dy3+ phosphors were prepared via sol-gel method by using the stoichiometric amounts of lithium nitrate LiNO3, barium nitrate Ba(NO3)2 and ammonium dihydrogen phosphate NH4H2PO4 as base materials. Morphology by scanning electron microscopy (SEM), structure by X-ray diffraction (XRD), thermal properties by Differential thermal analysis (DTA)/Thermogravimetric Analysis (TGA) and structural characteristics by Fourier transform infrared spectroscopy (FT-IR) were investigated. This paper presents luminescence properties using spectra from radioluminescence (RL), photoluminescence (PL), cathodoluminescence (CL) and, thermoluminescence (TL) and the influence of RE dopants (Tb3+, Dy3+) on the luminescent behavior of LiBaPO4. Computerized Glow Curve Deconvolution (CGCD) and Peak Shape Method were used to determine the kinetic parameters and the obtained results were evaluated. The RL results of un-doped LiBaPO4 showed the presence of a well-defined peak at 417 nm and a weaker band around 685 nm. Strong emissions were detected in the sample doped with Dy3+ correspond to 4F9/2→6Hj transitions. Blue, yellow and red emissions were observed with transitions of 4F9/2 → 6H15/2, 4F9/2 → 6H13/2 and 4F9/2 → 6H11/2, respectively. As for LiBaPO4: Tb3+, green emissions originated from the characteristic transitions (5D3 → 7FJ (j = 6–3) and 5D4 → 7FJ (j = 6–1)) of Tb+3 ion was seen. The RL, PL and CL spectra were identical, suggesting these green emissions. Dy3+ doped sample has three glow curves located at 72 °C, 145 °C and 204 °C, while the main temperature peak is measured at 240 °C for Tb3+ doped sample. Chromotographic studies of LiBa0·98PO4: Dy3+0.02 reveals that calculated x and y color coordinates (0.3122, 0.3233) are very close to the white light. © 2023