Browsing by Author "Gül, A"
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Item Organic cucumber growing in the greenhouseTüzel, Y; Gül, A; Karacanci, A; Anac, D; Okur, B; Ongun, AR; Yoldas, Z; Madanlar, N; Gumus, M; Tüzel, IH; Engindeniz, SThis study was conducted in order to elucidate the problems in organic greenhouse cucumber growing. Two dosages of farmyard manure (15 or 30 tons ha(-1)) were tested during autumn and spring seasons of 2003 and 2004. Fruit samples were analyzed for their quality parameters (color and total dry matter content of fruits and total soluble solids, EC and pH of fruit juice) at three weeks intervals during the harvest period. Generally, there were no significant differences with respect to fruit properties between manure dosages in both growing seasons. Higher yield was in the farmyard manure application of 15 ton ha(-1) (5.92 kg/m(2)) compared to the application of 30 ton ha(-1) (3.95 kg/m(2)) in autumn season, whereas higher total yield (17.84 kg/m(2)) was obtained from the plants grown by the application of 30 ton ha(-1) farmyard manure in spring, but the difference between treatments was not statistically significant.Item Organ Donation: knowledge and attitudes of Health College and other departments' students in a Turkish UniversityGül, A; Üstündag, H; Purisa, S; Gürgen, HObjective: The aim of the study was assess knowledge and attitudes on organ donation both in the Health College and other departments' students of the university. Methods: The study was carried out among the students enrolled in the Health College (1st group) and the other departments (2nd group) of the same university. A total of 609 university students were taken in the sample group. A questionnaire, with 19 questions, was developed by the researchers after reviewing the literature. Data evaluated with Chi-square and Fisher's exact test. Results: 90.6% of the students in the 1st group and 83% of those in the 2nd group were informed about organ donation. Willingness to donate was significantly higher among the 2nd group students (46%) than the 1st group (35.6%). However, while 4.2% of the 1st group students said that they carried legal donor cards, only 0.7% of the 2nd group students did so. 44.3% of the 1st group and 70% of the 2nd group said they did not know where to apply to become organ donors. 60.2% of the 1st group and 66.7% of the 2nd group reported that organ donation to be religiously appropriate. Conclusions: The results of the study indicate the need for more information and education to prepare university students about organ donation. Especially, the next generation of health care professionals must be targeted.Item Cryptosporidium spp. during chemotherapy: a cross-sectional study of 94 patients with malignant solid tumorKarabey, M; Can, H; Öner, TÖ; Döskaya, M; Alak, SE; Döskaya, AD; Karakavuk, M; Köseoglu, AE; Ün, C; Gürüz, AY; Alacacioglu, A; Pektas, B; Gül, A; Kaya, S; Gokmen, AABACKGROUND: Cryptosporidium spp. is a protozoan parasite that infects many vertebrate animals, including humans. Since Cryptosporidium spp. can cause chronic life-threatening diarrhea and severe malabsorption in immunocompromised patients, we investigated the prevalence of this parasite among patients undergoing chemotherapy for malignant solid tumors. OBJECTIVE: Investigate the prevalence of Cryptosporidium spp. in stool samples. DESIGN: Cross-sectional. SETTING: Tertiary care. PATIENTS AND METHODS: Stool samples were collected from adult patients with malignant solid tumors receiving chemotherapy and diarrhea. Cryptosporidium spp. prevalence was determined using Ziehl-Neelsen staining, ELISA, and real-time PCR targeting of the COWP gene. MAIN OUTCOME MEASURE: The prevalence of Cryptosporidium spp. in patients undergoing chemotherapy for malignant solid tumors. SAMPLE SIZE: 94 RESULTS: The prevalence was 2.1% (2/94), 5.3% (5/94), and 5.3% (5/94) as detected by Ziehl-Neelsen staining, real-time PCR and ELISA, respectively. The prevalence reached 8.5% (8/94) using all results obtained from the three methods. Among eight positive stool samples, four were positive by at least two different methods (Ziehl-Neelsen staining-ELISA or ELISA-real-time PCR) whereas the remaining four were positive by either ELISA or real-time PCR. CONCLUSION: These findings show the risk of cryptosporidiosis in cancer patients and the necessity to use at least two diagnostic methods during the diagnosis of cryptosporidiosis to reach more accurate and trustworthy results. LIMITATIONS: Further studies with a larger sample size are recommended. CONFLICT OF INTEREST: None.Item Investigation of the role of stray cats for transmission of toxoplasmosis to humans and animals living in Izmir, TurkeyKarakavuk, M; Can, H; Selim, N; Yesilsiraz, B; Atli, E; Sahar, EA; Demir, F; Gül, A; Özdemir, HG; Alan, N; Yalçin, M; Özkurt, O; Aras, M; Çelik, T; Can, S; Döskaya, AD; Gürüz, AY; Döskaya, MIntroduction: Toxoplasma gondii is a protozoan parasite that has a widespread distribution among mammalians and birds. One of the reasons for the high prevalence may be due to ingesting oocyst disseminated by stray cats' feces. In Turkey, most of the citizens are closely associated with stray cats and they love to pet and feed them on the streets. In this study, we aimed to determine the prevalence of T. gondii DNA in feces of stray cats living in Izmir, Turkey in order to identify the transmission potential to humans and other animals. Methodology: Feces and blood samples of 465 stray cats were investigated for the presence of T. gondii oocysts by microscopy and for the presence of T. gondii DNA by two real time PCR methods. Furthermore, serum samples were analyzed for anti-T. gondii IgG antibodies using an ELISA. Results: Oocysts were detected in 0.43% of the stray cats by microscopy. T. gondii DNA was detected in 14.37% of the stray cats' feces samples. The seroprevalence rate was 37.84%. In the feces and/or blood PCR positive group, 35.89% of them were seropositive. Among the 176 seropositive cats, T. gondii DNA was detected in feces of 27 cats (15.34%). Conclusions: This study first time showed the inter relation of T. gondii DNA in feces and blood samples and seropositivity. In sum, over 14% of the stray cats living outdoor may have an important role in transmission of toxoplasmosis to humans in Izmir as well as to other animals.Item The effect of metal type and gamma irradiation doses on the VOC detection performance of new 1,3-bis(2-pyridylamino)isoindoline complexesGümrükçü, S; Urfa, Y; Altindal, A; Kati, MI; Akyürekli, S; Gül, A; Sahin, Y; Özçesmeci, IIn this study, naphthoxy group substituted 1,3-bis(2-pyridylimino)isoindoline compounds containing nickel and copper metals were synthesized and characterized by NMR, FTIR, UV-vis, and mass spectroscopic methods. Thin film of these compounds is deposited on Plexiglas substrates decorated with Au interdigital electrode structure using spin coating method. The deposited films are then exposed to six doses of gamma irradiation between 1 kGy and 150 kGy using 60 Co as gamma source. The morphological and volatile organic compound (VOC) sensing properties of as-deposited and gamma-irradiated thin films are investigated using Atomic Force Microscopy (AFM) technique and current-time (I-t) measurement set up, respectively. The results of VOC sensing performance have shown that in naphthoxy group substituted 1,3-bis(2-pyridylimino)isoindoline compounds containing nickel and copper metals strongly dependence on the central metal. Under the same conditions, the maximum sensitivity was observed against methanol vapor in the NiBPI-based sensor, while the maximum sensitivity was observed towards ammonia vapor in the CuBPI-based sensor. The results obtained from examining the effect of gamma radiation dose on the VOC sensing performance of the sensors showed that gamma radiation dose has non-negligible effect on the VOC sensing properties of these compounds. For example, the response of CuBPI-based sensor towards ammonia vapors treated by 15 kGy gamma radiation was 18 times higher than that of bare CuBPI based sensor, the results obtained was correlated with the surface roughness of the films.Item Molecular prevalence of Blastocystis sp. and subtype diversity in fecal samples collected from cattle in dairy farms in TurkeyOner, TO; Karakavuk, M; Doskaya, AD; Guvendi, M; Gül, A; Koseoglu, AE; Alak, SE; Guruz, AY; Un, C; Doskaya, M; Can, HClose contact with infected animals is one of the main risk factors for zoonotic transmission of enteric protozoan parasite Blastocystis and thus, several animal species are being screened for the detection of the zoonotic subtypes. For this purpose, 22 fecal samples were collected from healthy cattle aged > 2 months and 39 fecal samples were also collected from cattle (aged <2 months) which are treated with TMP-SMX due to diarrhea. Later, Blastocystis sp. and subtypes were investigated by a PCR targeting the SSU rRNA gene and subsequently by sequencing. Among the 22 fecal samples collected from healthy cattle, Blastocystis was detected in 12 of them with a prevalence rate of 54.5 %. Among Blastocystis-positive samples, five different subtypes (ST3, ST5, ST10, ST12, and ST13) were detected. The predominant subtype was ST10 (allele 152) with a prevalence rate of 50 % (6/12). In the other group treated with TMP-SMX due to diarrhea, Blastocystis was detected in only one (2.56 %;1/39) fecal sample and its subtype was ST1 (allele 2). High prevalence of Blastocystis as well as predominance of ST10 (allele 152) were detected in healthy cattle. The identification of zoonotic ST1, ST3, ST5 and ST12 subtypes among the detected subtypes with a high prevalence (46.1 %; 6/13) showed the importance of cattle as a source for transmission of Blastocystis to humans. It was observed that the efficiency of TMP-SMX on the clearance of Blastocystis in cattle was very strong. Moreover, to our knowledge, this is the first study detecting Blastocystis ST13 subtype in the cattle.Item Impact of rheumatoid arthritis in Turkey: a questionnaire studyDireskeneli, H; Akkoç, N; Bes, C; Çakir, N; Çefle, A; Çobankara, V; Dalkiliç, E; Dinç, A; Ertenli, T; Gül, A; Hamuryudan, V; Inanç, M; Kalyoncu, U; Karaaslan, Y; Kasifoglu, T; Keser, G; Keskin, G; Kisacik, B; Kiraz, S; Masatlioglu, S; Onat, AM; Özbek, S; Öztürk, MA; Pamuk, ÖN; Pay, S; Pirildar, T; Sayarlioglu, M; Senel, S; Sentürk, T; Tasan, D; Terzioglu, E; Yazici, A; Yücel, EObjective Unmet needs of rheumatoid arthritis (RA) patients regarding physician/patient communication, treatment preferences and quality of life issues were investigated in a Turkish survey study. Methods The study was conducted with the contribution of 33 rheumatologists, and included 519 RA patients. The study population included patients who had been on biologic therapy for >6 months and were still receiving biologic therapy (BT group), and those who were biologic naive, but found eligible for biologic treatment (NBT group). Of the RA patients, 35.5% initially had a visit to an internal disease specialist, 25.5% to a physical therapy and rehabilitation specialist, and 12.2% to a rheumatology specialist for their RA complaints. The diagnosis of RA was made by a rheumatologist in 48.2% of patients. Results The majority of RA patients (86.3%) visit their doctor within 15-week intervals. Most of the physician-patient communication focused on disease symptoms (99.0%) and impact of the disease on quality of life (61.8%). The proportion of RA patients who perceived their health status as good/very good/excellent was higher in the BT group than in the NBT group (74.3% vs. 51.5%, p<0.001). However, of those RA patients in the NBT group, only 24.8% have been recommended to start a biologic treatment by their doctors. With respect to dose frequency options, once-monthly injections were preferred (80%) to a bi-weekly injection schedule (8%). Conclusion In conclusion, RA patients receiving biologic therapy reported higher rates of improved symptoms and better quality of life and seemed to be more satisfied with their treatment in our study.