Browsing by Author "Günay T."

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    The beneficial effects of physical exercise on antioxidant status in asthmatic children
    (2011) Onur E.; Kabaroĝlu C.; Günay T.; Var A.; Yilmaz T.; Dündar P.; Tikiz C.; Güvenç Y.; Yüksel H.
    Background: The pathogenesis of asthma involves both airway inflammation and an oxidant/antioxidant imbalance. It is demonstrated in asthmatic adults that exercise programmes improve lung function, a mechanism yet to be elucidated. The purpose of this study was to investigate the possible beneficial effects of physical exercise on antioxidant status in asthmatic children which may lead to ameliorated lung function. Methods: The study enrolled thirteen control and thirty asthmatic children. The asthmatic group was subdivided into two: the first group receiving only pharmacological treatment (n = 15) and the second receiving pharmacological treatment with exercise programme (n = 15) for 8 weeks. Blood samples were drawn from the subjects before and after treatment periods. As oxidant stress markers blood levels of malondialdehyde (MDA) and total nitric oxide (NO), and as antioxidant status, glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) enzyme activities were assessed. Results: Before any treatment was initiated, MDA and NO levels in the asthmatic group were significantly higher than the controls (3.40 ± 0.96 nmol/ml vs 2.46 ± 0.58 nmol/ml, and 12.53 ± 2.10 vs 9.40 ± 1.39 micromol/L, respectively). Both SOD (p = 0.0001) and GSH-Px (p = 0.023) activities were significantly lower in the asthmatic group. Pharmacological treatment and exercise programme together significantly improved lung performance and decreased the levels of oxidant stress markers, in concordance with a significantly increase in antioxidant enzyme activity measures when compared to the pharmacological treatment. Conclusion: Structured exercise programme in asthmatic children resulted in better lung function, which may be attributed to its effect on antioxidant status. © 2010 SEICAP.
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    Smoking cessation and the effect of nicotine dependence on relapse rate in İzmir, Turkey
    (Turkiye Klinikleri, 2015) Pekel Ö.; Ergör G.; Günay T.; Baydur H.; Choussein B.; Budak R.; Doğanay S.
    Background/aim: Smoking is the leading preventable cause of death in the world. There is growing evidence of the need for communitybased programs on smoking cessation. The main purpose of this study is to establish the rate of smoking cessation and restarting in 1 year at the Balçova Smoking Cessation Center. Materials and methods: This is a prospective study with a study group of 359 individuals who quit smoking at the Balçova Smoking Cessation Center for at least 4 weeks between October 2009 and April 2010. The outcomes of the study were 1-year cessation rate and relapse rate. Individuals who reported restarting and/or had CO measurements above 6 ppm were accepted as quitters who had relapsed. Results: The 1-year rate of smoking cessation was 30.1% for the study group. Of the subjects who quit smoking, 50.1% started smoking again during the 1-year follow-up. Relapse rate was also higher in nicotine addicts. Pharmacological treatment was associated with increased success rates in smoking cessation. Conclusion: Nicotine dependency was shown to be associated with lower rates of smoking cessation and higher rates of relapse. Therefore, it is important to begin smoking cessation attempts before individuals become serious addicts. © TÜBİTAK.
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    Attitudes of the Turkish University Students and Staff Toward Sexual Harassment and Assault: Preliminary Psychometric Evaluation
    (SAGE Publications Inc., 2021) Siyez D.M.; Ercan G.S.; Esen E.; Soylu Y.; Baran B.; Firuzan E.; Belkis Ö.; Dündar Sezer T.; Efe Güney M.; Ergönen A.T.; Günay T.; Tezcan S.; Öztürk B.
    The aim of this study was to develop a scale to measure the attitudes of the university academic and administrative staff and students toward sexual harassment and assault, and examine its psychometric properties. After the development of the item pool and examination of the content validity of the intended items, Exploratory Factor Analysis (EFA) and parallel analysis was conducted and Cronbach’s alpha reliability coefficient was calculated collecting data from 150 participants (54.7% of female and 45.3% of male) for the initial version (comprised of 12 items) of the Attitudes Toward Sexual Harassment and Assault Scale (ATSHAS). In the second phase, Confirmatory Factor Analysis (CFA) was conducted with 354 participants (54% of female and 46% of male) for the revised version (10 items) of the ATSHAS. Additionally, Cronbach’s alpha reliability coefficient was calculated with second sample. After developing the item pool, the completion of the first phase of the study took 5 months, and the second phase took 4 months. The final version of the ATSHAS consisting of nine items demonstrated sufficient psychometric properties for measuring attitudes toward sexual harassment and assault in the university environment. © The Author(s) 2021.
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    FACTORS AFFECTING SMOKING CESSATION SUCCESS IN INDIVIDUALS WHO APPLIED TO A SMOKING CESSATION CENTRE
    (Czech National Institute of Public Health, 2024) Günay T.; Acar N.; Lüleci D.; Seven F.; Durukan N.Ş.; Baydur H.; Kilinç O.; Taner Ş.
    Objectives: This study aims to assess the frequency of smoking cessation and to identify the factors affecting smoking cessation success among individuals seeking assistance at a smoking cessation centre. Methods: This cross-sectional study included 1,570 individuals who applied to the smoking cessation centre in Izmir, Turkey, between 2009 and 2018, and completed three follow-ups. Data were obtained from the centre’s records. Factors affecting smoking cessation success were analysed using logistic regression in multivariate analysis. Results: The median age to start smoking was 19 (17–22), and the median number of cigarettes consumed per day was 20 (20–30). Among the participants, 59.9% exhibited a high/very high level of nicotine dependence, and 79.6% had attempted to quit smoking previously. The median number of patient follow-ups was 7 (5–10). Of the patients, 34.0% successfully quit smoking for one year. According to the multivariate analysis results, smoking cessation success increased with being married by 2.26 times (95% CI: 1.51–3.38, p < 0.001), the absence of other smokers in the household by 1.38 times (95% CI: 1.01–1.88, p = 0.04), having a low level of nicotine dependence by 1.75 times (95% CI: 1.23–2.48, p = 0.002), and more patient follow-ups by 1.61 times (95% CI: 1.52–1.72, p < 0.001). Conclusions: Smoking cessation success is increased by the support and follow-up provided by healthcare professionals, the absence of other smokers in the household, and a low level of nicotine dependency. © 2024, Czech National Institute of Public Health. All rights reserved.