Browsing by Author "Gulbagca F."

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    Compression of the effect of pulsed electromagnetic field and pulsed radio frequency energy on wound healing in rats; [Darbeli elektromanyetik alan ve darbeli radyofrekans uygulamalarinin siçanlarda yara iyileşme etkilerinin karşilaştirmasi]
    (Institute of Electrical and Electronics Engineers Inc., 2017) Gumusay M.; Gulbagca F.; Saygili S.; Aydemir I.; Kaya A.; Tuglu M.I.
    Delayed or not sufficiently good wound healing is a significant problem in medical treatment is needed to support in order to improve healing. Low frequency electromagnetic field (EMF) applications are seems to give this support. Disturbed vascularization, connective tissue formation, matrix exchange, and inflammation process in the wound environment are modified after EMF applications compared with control groups. Deteriorations in these factors which can be returned with the electrical impulses, DNA synthesis, transcription and transforms of protein synthesis, increasing of fibroblasts and endothelial cell proliferation indicate the presence of EMF mechanisms. Since the application and ambient conditions are kept constant but the type of the application has been changed in our study, it was provided that pulsed radio frequency energy (PRFE) is more effective and has more long-term improvement compared to pulsed electromagnetic fields (PEMF). The effects of these applications on cells and understanding of the mechanisms of the behavior will be much more significant and meaningful contribute to the treatment. © 2016 IEEE.
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    Development of electromagnetic field system for providing wound healing on created wound model rat skin and sensor application; [Sicąn Derisinde Olusturulan Yara Modeli Üzerinde Iyilesme Saglanmasi için Elektromanyetik Alan Sistemi Gelistirilmesi ve Sensör Uygulamasi]
    (Institute of Electrical and Electronics Engineers Inc., 2017) Gumusay M.; Gulbagca F.; Aydemir I.; Saygili S.; Kaya A.; Tuglu M.I.
    Electromagnetic field (EMF) radiation are formed by the acceleration of electric charge. Electric charges produce electric and magnetic energy in space when they move. These waves have different frequencies and wavelengths and when they interact with an object they can be refracted, reflected or absorbed. When a suitable frequency and waveform EM signal is applied to the target tissue with the help of a coil or applicator physiological effects will occur at the cellular size. Today studies revealed significant molecular mechanisms occurring during wound healing. Non-ionizing part of the EM spectrum is low-frequency electromagnetic fields are used as adjunct therapy in soft tissue injuries. In this study, the main goal is development of systems which will give better results compared with conventional treatment methods taking into account the effect on rat skin. To achieve this, some improvements in output power, increased gain, versatility, easy adjustments are provided for the spiral and planar antenna-applicator design. © 2016 The Chamber of Turkish Electrical Engineers.
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    Design of coils driven by pulsed electromagnetic field generator and the effect of wound healing in rats; [Darbeli elektromanyetik alan jeneratörü ile sürülen bobin tasarimlari ve siçanlarda yara iyileşme etkileri]
    (Institute of Electrical and Electronics Engineers Inc., 2017) Gumusay M.; Gulbagca F.; Saygili S.; Aydemir I.; Kaya A.; Tuglu M.I.
    Chronic wound healing is an important problem especially in diabetic and the elderly which is needed development of the current treatment methods. Electromagnetic fields (EMF) has a significant impact on our body. These fields are being used for bone problems, cartilage regeneration, and pain removal for physiotherapy purposes. Lately, EMFs are often used in in vitro and in vivo assays. In this study, in vivo test results of the applied pulsed electromagnetic fields (PEMF) with our designed Helmholtz coil array system are given. The skin wound healing conducted in rats as an experimental model provides important information for evaluating the efficacy and mechanism of these kind of treatments. For this purpose, effectiveness of PEMF compared to control groups on experimental skin healing effect was examined macroscopically. Compared with the control groups a faster wound healing process was followed by PEMF application at 75 Hz frequency. © 2016 IEEE.
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    The effect of electro magnetic fields on cell behaviour; [Elektro Manyetik Alanlarin Hücre Davranisina Etkisi]
    (Institute of Electrical and Electronics Engineers Inc., 2017) Tuglu M.I.; Gulbagca F.; Sal D.H.; Saygili S.; Sonmez P.K.; Aydemir I.; Ozkut M.; Ozturk S.; Gumusay M.; Kaya A.; Keskin N.
    The biologic effects of electomagnetic fields application on medical field has been increased. Their effect on medical treatment depends on cell behaviour which can be observed by in vivo and in vitro studies. Their effect on the stem cells and the cell lines and the organs of experimental animals with morphological alterations are helpful to understand cell behaviour. The behaviour of the cells can be analyse at ultrastructural level by scaning electron microscopy. Application of electomagnetic fields cause increase of proliferation, migration and improvement of wound healing with beneficial effects while they cause oxidative stress and cell death including apoptosis for cancer cells in different types of cell line. The minimal side effect with maximum beneficial treatment of these products suggest that they could be very useful for clinical trials. © 2016 IEEE.
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    Design of antenna-applicator for electromagnetic field applications and excitation model for rat and heat transfer analysis; [Elektromanyetik Alan Uygulamalari için Anten-Aplikatör Tasarimi, Sicąn için Uyartim Modeli ve Isi Daglimi Analizi]
    (Institute of Electrical and Electronics Engineers Inc., 2017) Gumusay M.; Gulbagca F.; Aydemir I.; Saygili S.; Kaya A.; Tuglu M.I.
    There has been only a few technical progress which contribute to wound healing in the last century. Despite these advances wound healing is very hard issue to study because of its subjectivity, diversity and complexity of the wound healing process and diversity of patients. Molecules are insufficient in the chronic wound and unlike other cells multiplying endothelial cells interrupt the healing process. To restart this process, cells can be excitated by pulsed electromagnetic fields stimulation method. When a suitable frequency and waveform electromagnetic field (EMF) signal is applied to the target tissue with the help of a coil or applicator physiological effects occurs at the cellular size. Low-frequency electromagnetic fields are non-ionizing part of the EM spectrum and they are used as adjunct therapy in soft tissue injuries. In this study, an antenna-applicator design was performed and the effect of non-thermal pulsed radio frequency energy (PRFE) system to the wound created rat skin was examined. © 2016 The Chamber of Turkish Electrical Engineers.
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    Effects of electromagnetic fields application on experimental varicocele model in rats; [Sicanlarda Deneysel Varikosel Modelinde Elektromanyetik Alan Uygulamalarinin Etki]
    (Institute of Electrical and Electronics Engineers Inc., 2017) Gulbagca F.; Sal D.H.; Saygili S.; Sonmez P.K.; Aydemir I.; Ozkut M.; Ozturk S.; Gumusay M.; Kaya A.; Tuglu M.I.
    Varicocele is the most clinical condition which can be treated by surgery. The frequency in male is 20%. The half of infertile patient has this pathology which there is dilatation in plexus pampiniformis veins of testes. Varicocele causes increase of heat or increse of oxidative stres in seminifer tubules where they produce pathology for spermatogenesis. Low frequency magnetic fields are useful for the treatment of many area where they become important role. In this study the effect of low frequency magnetic fields on the experimental varicocele model of rat testes was investigated. The parameters for oxidative stres suggest eNOS and iNOS with apoptosis were evaluated by immunohistochemical staining. There was increaese in eNOS, iNOS and apoptosis by the varicocele experiment where there was testicular damage and low frequency magnetic fields caused decrease in oxidative stress and apoptosis. Application of magnetic fields can help the clinical varicocele pathologies either with treatment or supportive effect. © 2016 IEEE.