Browsing by Author "Gunduz, T"

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    Microbiological investigation of stool in patients with acute diarrhea
    Gunduz, T; Cumen, S; Ari, A; Demirel, MM; Etiz, S; Tay, Z
    Acute gastroenteritis is an important health public issue especially in developing countries. The aim of this study was to determine the most common microbial agents responsible for acute diarrheas in our city. The study was performed prospectively between December 2005 and January 2006 in Manisa, Turkey. Stool samples were collected from patients with acute diarrhea who attended to different hospitals of the city (University Hospital, Government Hospitals, Pediatrics Hospital and Health Public Laboratory). The stool samples of 300 patients (50 children, 250 adults) were investigated. Standard cultivation methods were performed to determine Salmonella ve Shigella spp. Escherichia coli 0157:H7 was tested by ImmunoCard STAT! E. coli 0157 Plus. The strains that were identified as sorbitol negative E. coli were investigated by E. coli 0157: H7 antiserum. The isolated microorganisms were as follows: Salmonella spp. 7 (2.3%), Shigella spp. 5 (1.6%), Giardia intestinalis 12 (4%), Enterobius vermicularis 5 (1.6%), Rotavirus 2 (0.6%) and sorbitol negative E. coli 18 (6%). Only one Sorbitol negative E. coli colony showed agglutination with E. coli 0157:H7 antiserum. The most common pathogens were identified as G. intestinalis in children and E. coli in adults. Sorbitol negative E. coli were isolated in 18 of the stool samples, and only one of them showed agglutination with E. coli 0157:H7. Although rare, this strain may lead serious complications and it should be kept in mind in patients with acute diarrhea.
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    INVESTIGATION OF HAND HYGIENE KNOWLEDGE LEVEL OF PHYSIOTHERAPY AND REHABILITATION STUDENTS
    Ilgin, D; Karaali, HK; Ozcan, O; Arslan, S; Arslan, T; Gunduz, T; Limoncu, ME
    Introduction: Increasing health care students' awareness about the hand hygiene (HH) during the pre-graduation period becomes an important requirement for providing both patient's safety and the healthcare student's safety by preventing healthcare associated infections (HCAIs). Although it has been emphasized that rehabilitation clinics are important places to be taken into consideration in the transmission of HCAIs, the number of studies about the students from department of physiotherapy and rehabilitation (DPR) are limited. Thus, our research was done to examine the HH knowledge level of students of DPR. Materials and methods: This cross-sectional study was done by 191 volunteers from a total of 209 first and second-year students. We recorded the sociodemographic characteristics. Based on the suggestions commented in the Center for Disease Control and Prevention Guideline for HH in Health Care Settings, HH knowledge levels were assessed using face to face interview technique. Results: The average correct answer rate to the questions about the HH knowledge level was 69.49%. The level of knowledge about the importance of HH was good, but the correct response rates for terminology and alcohol-based handrub were less than 50%. Conclusions: Since DPR students form an important ring in the therapy chain, so in the development of educational programs for the students of DPR, it is very important to improve their knowledge level especially about terminology and alcohol-based handrub techniques.
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    Does chronic exercise alter immune parameters in postmenopausal women?
    Karadeniz, G; Buyukyazi, G; Gunduz, T; Kutlu, N; Ozbakkaloglu, B
    The aim of this study was to determine the effect of chronic exercise on immune functions. Eighteen postmenopausal women were included in the study: nine were undertaking chronic exercise (exercise group) and the other nine were sedentary (control group). The exercise group had been training for 7.2 h per week for 19.9 years, The subjects were chosen among postmenopausal women to eliminate any effects of menstrual cycle on the immune system. The subjects were paired and reported to the Human Performance Laboratory twice a week between 8:00 and 10:00 a.m. In the first visit, body composition and aerobic capacity were measured. In the second visit, their blood samples were drawn and screened immediately. VO(2)max was significantly higher in the exercise group. The leukocyte and lymphocyte subset data comparions demonstrated no significant difference between the exercise group and the control group. Only IgA was significantly higher in the exercise group than in the control group (p = 0.005). The results of this investigation indicate that chronic exercise training does not significantly alter concentrations of T and B lymphocytes or T lymphocyte subsets. However, a significant increase in IgA levels may occur, leading to changes in immune response.
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    Epidemiological profile of onychomycosis in the elderly living in the nursing homes
    Gunduz, T; Gunduz, K; Degerli, K; Limoncu, ME
    Introduction: Few data is available about the prevalence and the causative microorganisms of onychomycosis in the elderly. The aim of this study was to determine the prevalence and types of onychomycosis in the elderly people living in the nursing homes and to determine the responsible fungal agents. Methods: Elderly people living in nursing homes were examined for onychomycosis. Nails with color and structure changes were suspected of onychomycosis. Scraping materials were evaluated by direct KOH examination and fungal cultures were performed. Results: Totally, 214 elderly persons (59 female, 155 male) from nursing homes were studied. Onychomycosis was suspected clinically in 102 cases and scraping materials were obtained from 122 nails. Clinical types of onyhomycosis were distal subungual in 87, proximal subungual in 21 and white superficial in 14 cases. Fungal spores were seen in 81 (37.8%) samples (3 hand nails, 78 toenails) with direct KOH examination and fungal culture was positive in 54 (25.2%) (3 hand nails, 51 toenails) of them. Trichophyton rubrum was the most frequently isolated fungus (75.9%) followed by Candida glabrata (12.9%). Conclusions: In the elderly, onychomycosis is more common than the general population. However causative fungi are similar; dermatophytes are the most common causative organisms followed by yeasts. (C) 2013 Elsevier Masson SAS and European Union Geriatric Medicine Society. All rights reserved.
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    Investigation of inducible clindamycin resistance among clinical isolates of staphylococci
    Gunduz, T; Akgul, S; Ozcolpan, G; Limoncu, ME
    The aim of this study was to investigate the inducible clindamycin resistance in 306 strains of staphylococci, isolated from various clinical samples over a period of two years. Inducible clindamycin resistance was investigated by D-test using clindamycin and erythromycin discs as per the CLSI guidelines. Out of 177 Staphylococcus aureus strains 53 (17.3%) were methicilline resistant S. aureus (MRSA) and 124 (40.5 %) were methicillin sensitive S. aureus (MSSA). Among the coagulase negative staphylococci, 121 (39.6%) were methicillin sensitive and 8 (2.6%) were methicillin resistant. Out of 306 clinical isolates 99 (36.4%) showed erythromycin resistance. Among the erythromycin resistant isolates 46 (46.5%) were CoNS of which 8 (15.1%) were MRCoNS and 38 (31.4%) MSCoNS. Out of thirty-one erythromycin resistant isolates 20 (6.5% of the total isolates) belonged to MLSBi phenotype, eleven isolates belonged to MLSBc phenotype. We conclude that it is necessary to perform D-test for detection of inducible clindamycin in staphylococci in routine antibiotic susceptibility testing.
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    Evaluation of hepatitis B surface antigen, anti-hepatitis C virus and anti-human immunodeficiency virus antibodies and syphilis seropositivity in blood donors
    Gunduz, T; Mumcuoglu, I; Güray, M
    This retrospective study was carried out to evaluate the seropositivity of hepatitis B surface antigen (HbsAg), anti-hepatitis C virus (HCV), anti-human immunodeficiency virus (HIV) and syphilis in blood donors in Manisa Government Hospital. Data were evaluated in 10, 189 blood donors between April 1, 1997, which is the time from which regular records began to be collected, and April 1, 2003. The blood samples of the blood center from April 1, 1997, to January 1, 1998, were examined via the card method, those between January 1, 1998, and January 1, 2002, were examined via micro enzyme-linked immunosorbent assay (ELISA) method and the rest were evaluated with macro ELISA methods. In blood donors, the positivity of HbsAg, anti-HCV anti-HIV and the rapid plasmin reagin test were 2.95%, 0.68%, 0.00% and 0.16%, respectively.