Browsing by Author "Gurkan, A"

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    Stress Coping Strategies in Hemodialysis and Kidney Transplant Patients
    Gurkan, A; Pakyuz, SÇR; Demir, T
    Objective. The aim of this study was to determine the levels of anxiety and depression, and stress coping strategies used by hemodialysis and kidney transplant patients. Methods. This study included 138 hemodialysis patients treated at the two private dialysis centers and 76 kidney transplantation patients followed up at the private hospital. Data were collected with socio-demographic characteristics, the Hospital Anxiety and Depression Scale, and the Coping Strategies Questionnaire (COPE). Results. The anxiety and depression scores were significantly lower among the transplant group versus the hemodialysis patients. The use of non-functional coping strategies was higher among the patients who were treated with hemodialysis, compared to the renal transplantation patients. The use of problem focused and emotional focused coping strategies were higher among the renal transplant patients, compared to hemodialysis patients. When all participants were evaluated together, turning to religion was the most frequent coping strategy followed by active coping, and positive reinterpretation. In hemodialysis patients, there was a significantly negative correlation between age and problem-focused, emotion-focused and non-functional coping strategies. In contrast, the correlation between education level and both problem-focused and emotion-focused coping strategies was significantly positive. In transplant patients, gender and education level were significantly negative correlated with emotion-focused coping strategies. Conclusion. The results of data analysis showed that the hemodialysis patients used fewer functional coping strategies and had more anxiety and depression than kidney transplant patients. It would be helpful to know an individual's coping strategies in the case of a stressful situation in order to determine treatment goals and monitor therapeutic efficacy.
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    Full-mouth disinfection effects on gingival fluid calprotectin, osteocalcin, and N-telopeptide of Type I collagen in severe periodontitis
    Afacan, B; Cinarcik, S; Gurkan, A; Ozdemir, G; Ilhan, HA; Vural, C; Kose, T; Emingil, G
    Background To compare the effects of full-mouth disinfection (FMD) and full-mouth ultrasonic debridement (FMUD) on clinical, microbiological and biochemical parameters with conventional quadrant-wise scaling and root planning (Q-SRP) in severe chronic periodontitis. Methods In the present prospective randomized controlled clinical trial with three parallel arms (#NCT04038801), 60 chronic periodontitis patients were randomly assigned to three study groups by a consecutive number in ascending order: FMD (n = 20), FMUD (n = 20), and Q-SRP (n = 20). All measurements and treatments were performed by the same investigator. At baseline, gingival crevicular fluid (GCF) and subgingival plaque were collected and clinical periodontal parameters were recorded. Ultrasonic debridement was completed within 24 hours in FMD and FMUD groups. Chlorhexidine gluconate was used for FMD. Q-SRP was performed by hand instruments per quadrant at 1-week-intervals. Clinical measurements and sampling were repeated at 1, 3, and 6 months after treatment. Real-time PCR was used for quantitative analysis of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, Fusobacterium nucleatum, and total bacteria count. GCF Calprotectin, osteocalcin, and N-telopeptide of type I collagen (NTx) levels were analyzed by ELISA. The changes of GCF biomarker levels after treatment between groups were the primary outcomes. Results No harm was observed. All treatment strategies resulted in significant improvements in all clinical parameters (P < 0.05), with no significant differences between study groups at all time-points (P > 0.05). Aggregatibacter actinomycetemcomitans was significantly decreased in FMD compared to FMUD and Q-SRP at 6 months (P < 0.05). Although GCF NTx total amounts increased in all groups during the study period, this increase was less prominent in full-mouth groups at three time points after treatment (P < 0.05). Conclusions Present results represent the short-term effects. Full-mouth treatment approaches offered limited beneficial effects on microbiological and biochemical parameters over quadrant-wise approach. All three treatment strategies can be recommended in the management of severe chronic periodontitis.