Browsing by Author "Hakan, N"

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Premature labor and leukoerythroblastosis in a newborn with parvovirus b19 infection
    Gulen, H; Basarir, F; Hakan, N; Ciftdogan, DY; Tansug, N; Onag, A
    Leukoerythroblastosis is a rarely observed disease characterized by the presence of leukocytosis, erythroid and myeloid blast cells in peripheral blood. As to our knowledge, it was not diagnosed in a premature newborn before. A female case of 1164 grams who was born prematurely at 29th week of gestation by cesarean section was referred to our newborn intensive care unit due to prematurity and respiratory distress with no prenatal pathological findings. Physical examination revealed tachypnea and hepatosplenomegaly. Routine laboratory measurements of the case showed significant leukocytosis (85.000/mm(3)) and anemia (Hb: 9.6 gr/dL and Hct: 27.6%). Thrombocyte count was normal. Peripheral blood smear suggested leukoerythroblastosis with the presence of nucleated erythrocyte, monocytosis, and 4% blasts. Bone marrow cytogenetic examination was normal. Parvovirus B19 Ig G and M serology were detected to be positive. The etiological factors observed in leukoerythroblastosis occurring during neonatal and early childhood period are congenital-postnatal viral infections, juvenile myelomonocytic leukemia and osteopetrosis. As to our knowledge, no case diagnosed with leukoerythroblastosis in such an early phase is avaliable in literature. As a result, premature delivery and leukoerythroblastosis presentation was thought to develop secondary to intrauterine parvovirus B19 infection.
  • No Thumbnail Available
    Item
    Cord blood nucleated red blood cell level: is it a predictive marker for neonatal jaundice?
    Orhon, A; Topal, H; Hakan, N; Ozer, EA
    Background: The aim of this study was to evaluate if the cord blood nucleated red blood cell (nRBC) levels can predict the development of hyperbilirubinemia in healthy neonates. Methods: All healthy newborn infants born after 35 or more weeks of gestation at our hospital between January 2016 and April 2017 were included. The levels of nRBC were counted in umbilical cord blood samples. Neonates were grouped into two study groups based on the presence or absence of neonatal jaundice. Results: The study included overall 149 eligible newborn infants. The levels of nRBC and absolute nRBC count showed statistically significant differences between newborns with or without jaundice (p =0.01 and 0.02, respectively). Conclusions: We suggest that increased nRBC counts in cord blood may be a predictive marker for hyperbilirubinemia in healthy newborn infants.