Browsing by Author "Happle, R"

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    Incontinentia pigmenti Stage 1 is not simply vesiculo-bullous but vesiculo-pustular
    Çetinarslan, T; Fölster-Holst, R; Van Gysel, D; Buchner, M; Happle, R
    Incontinentia pigmenti (IP) is a rare X-linked dominant, male-lethal disorder characterized by pathognomic skin lesions. As described in the literature the typical cutaneous changes follow the pattern of Blaschko's lines and develop in four stages that usually start at birth. Stage 1 is called vesicular, bullous or inflammatory. The vesicles are rapidly filled with eosinophils and thus turn into pustules. Thus, the term pustular is relevant to the first phase of IP, and the stage can be considered as vesiculopustular/inflammatory to be more precise than vesicular or bullous.