Browsing by Author "Içelli I."

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    Acute exacerbation of positive symptoms in schizophrenia during quetiapine treatment: Five case reports; [Ketiapin saǧaltimi sirasinda şizofreninin pozitif belirtilerinde ortaya çikan akut alevlenme: Beş olgunun sunumu]
    (2001) Danaci A.E.; Aydemir Ö.; Içelli I.
    Quetiapine is an atypical antipsychotic which has been recently submitted for clinical use in Turkey. Studies revealed that quetiapine is effective on the positive and negative symptoms of schizophrenia and has less side effects compared to conventional antipsychotics. In this article 5 cases, who had been followed with diagnosis of schizophrenia for a long time and had acute exacerbation in positive symptoms during quetiapine treatment, are presented. In literature no articles about side effects of quetiapine were found. The possible reasons of this condition occurring in Turkey was discussed and a study on the pharmacokinetic properties of quetiapine based on this report is proposed.
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    Postnatal depression in Turkey: Epidemiological and cultural aspects
    (2002) Esen Danaci A.; Dinç G. Gönül; Deveci A.; Seyfe Şen F.; Içelli I.
    Background. In some periods of a woman's life the risk of depression increases and the postnatal period is one of these. The prevalence and the risk factors of postnatal depression are not systematically studied in Turkey. The aim of this study is to investigate the epidemiological aspects and the cultural factors that may affect postnatal depression in our country. Method. According to the records of ten primary health care centres in Manisa, a city in western Turkey, there were 1,337 women who had given birth in the previous 6 months. A sample group of 317 mothers were randomised among these women and 257 (81.7 %) of the sample group could be reached. Data were collected by use of the Edinburgh Postnatal Depression Scale and a questionnaire on sociodemographic variables designed for this study. Results. The mean depression score was found to be 7.54±4.66. When the cut-off point was taken into consideration, 14% of mothers had a syndromal depression. The factors which affected the prevalence of depression were the number of living children, living in a shanty, being an immigrant, serious health problems in the baby, previous psychiatric history, psychiatric disorder in the spouse, and having bad relations with the spouse and his parents. Conclusion. These findings revealed that the prevalence of postnatal depression in the Manisa province and the factors affecting it were very similar to other studies; but the negative impact of bad relations of the mother with her family-in-law on postnatal depression seems to be a distinguishing aspect of Turkish culture.
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    Diabetes mellitus due to olanzapine use: A case report; [Olanzapin'e baǧli diabetes mellitus: Bir olgu sunumu]
    (2003) Danaci A.E.; Mizrak S.; Hekimsoy Z.; Içelli I.
    Olanzapine, a serotonin-dopamine-receptor antagonist, is an atypical antipsychotic agent used to treat schizophrenia and other psychotic disorders. It has relatively low frequency of side effects such as sedation, orthostatic hypotension, extrapyramidal symptoms, and anticholinergic side effects. Here, a 32-years-old female patient with schizophrenia who developed diabetes after 3 years of olanzapine treatment is presented. Due to lack of family history and immune marker positivity in the occurrence of diabetes, the condition was attributed to olanzapine treatment. After discontinuation of the treatment DM was improved. Controlled studies are necessary both to elucidate the mechanism by which olanzapine can cause dysregulation of glucose homeostasis, and to develop guidelines for the use of olanzapine in patients with known as well as in patients with risk factors for diabetes.