Browsing by Author "Ilker, SS"
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Item Septo-Optic Dysplasia: A Case ReportBilgin, S; Ilker, SS; Türker, I; Kiliç, SAn 18-year-old male patient was admitted with loss of vision in the right eye and blurred vision in the left eye. The right eye did not respond to the stimuli in the pattern visual evoked potentials (PVEP) test, and there was a significant delay in the p100 latency in the left eye. Cranial magnetic resonance imaging (MRI) showed a decrease in the calibration of both optical nerves, absence of septum pellucidum, and deformity in both frontal horns of the side ventricles. Despite the rare incidence of Septo-optik displazi (SOD), it should be considered in cases of unilateral or bilateral visual complaints, especially if optical nerve hypoplasia is also present.Item Effect of propolis on endotoxin-induced uveitis in rabbitsÖztürk, F; Kurt, E; Inan, ÜÜ; Emiroglu, L; Ilker, SS; Sobaci, GPurpose: To test the anti-inflammatory effect of propolis, a natural bee-produced compound, and compare it with corticosteroids fur the: treatment of endotoxin-induced uveitis (EIU). Methods: EIU was produced in all rabbits by unilateral intravitreal injection of 2,000 ng Salmonella typhimurium endotoxin. The animals were then divided randomly into three groups as follows: group A received no treatment (control), group B received methylprednisolone (5 mg/0.1 mL) (positive control); and group C received propolis (5 mg/0.16 mL) by anterior sub-Tenon injection at the time of uveitis induction and at 4 and 8 hours after induction. Inflammation was evaluated by clinical manifestations and by measuring the protein concentration and inflammatory cell content of the aqueous humor. Results: The clinical grade, cell count: and protein levels in the aqueous humor were: control group (6.0 +/- 0.8, 2,519 +/- 470 cells/mu L. 32.9 +/- 2.4 mg/mL); methylprednisolone group (1.8 +/- 0.7, 572 +/- 137 cells/mu L. 15.2 +/- 1.8 mg/mL); and propolis group (2.3 +/- 0.5, 503 +/- 124 cells/mu L, 13.8 +/- 1.5 mg/mL). Statistically significant differences were recorded in the treatment groups when compared to the control group (P < .001). The effects of methylprednisolone and propolIs on EIU were similar (P > .05). Conclusions: Propolis showed significant anti-inflammatory effects on EIU iii rabbits. The mechanism of its action warrants further investigation. Jpn J Ophthalmol 1999;43:285-289. (C) 1999 Japanese Ophthalmological Society.Item Pulsatile Proptosis and Sphenoid Wing Dysplasia with no Evidence of Neurofibromatosis Type 1: A Case Report and Review of the LiteratureAkgün, YD; Erdogan, M; Altinisik, M; Mayali, H; Ilker, SSIn this study, we aimed to present a rare case of pulsatile proptosis due to sphenoid wing dysplasia without the features of neurofibromatosis type 1 (NF1). A 17-year-old male patient presented with swelling in the superotemporal region of the right eye. Physical examination revealed facial asymmetry with a pulsatile, ill-defined, soft lesion with in the superotemporal region of the right orbit associated with pulsatile proptosis, downward dystopia, and hypotropia. Computer tomography imaging to establish a differential diagnosis showed temporal lobe herniation secondary to sphenoid wing dysplasia. The patient was assessed for NF1, which is most commonly associated with sphenoid wing dysplasia, but no evidence supporting the diagnosis was found. Patients presenting with proptosis should be carefully examined for pulsation and murmurs, and a trauma history should be investigated. Radiological imaging should be used to facilitate the differential diagnosis, and the current clinical condition should be managed with a multidisciplinary approach.Item Relationship between serum lipoprotein (a) levels and retinopathy in patients with type 2 diabetesKurt, E; Öztürk, F; Ari, Z; Yigitoglu, MR; Sari, RA; Ilker, SSWe studied whether there was an association between development of background or proliferative retinopathy and changes in plasma lipid, lipoprotein, and lipoprotein (a) levels in 111 patients with type 2 diabetes mellitus and in 57 controls. Serum lipoprotein (a) levels were higher in patients with retinopathy than in individuals without retinopathy. Increased serum lipoprotein (a) levels correlated with higher degrees of retinopathy. Thus, lipoprotein (a) may play a role in the development of diabetic retinopathy.Item Risk Factors of Peroperative Suprachoroidal HaemorrhageKayikiçoglu, OR; Emre, S; Demiray, B; Baser, E; Kurt, E; Ilker, SSPurpose: The aim of this study is to evaluate peroperative risk factors of patients who had suprachoroidal haemorrhage during different types of intraocular surgeries. Material and Method: We retrospectively evaluated general risk factors of five patients who had suprachoroidal haemorrhage. For that purpose, we reviewed the preoperative systemic and ophthalmologic recordings, performed procedures, and complications during and after the surgery from patients' files. Results: Suprachoroidal haemorrhage developed during cataract surgery with phacoemulsification in three cases, in a combined glaucoma and cataract surgery in one, and pars plana vitrectomy in one case. As surgical risk factor, one case had posterior capsular rupture, one hypermature cataract and one previous retinal detachment surgery. In the case with age-related macular degeneration and intravitreal heamorrhage, suprachoroidal haemorrhage arose during pars plana vitrectomy. Only the patient who underwent combined mini-nuc and trabeculectomy procedure had expulsive haemorrhage. As systemic risk factors all the patients were elderly, systemic hypertension, pain during the surgery, anxiety related to panic atac and prostate hypertrophy were other detected risk factors. Discussion: According to our clinical experiences, detected risk factors in our patients were in concordance with literature data. In addition to this, despite the smaller incision size trend in ophthalmic surgery, suprachoroidal haemorrhage is still an important potential complication, particularly in patients who had previous ocular surgeries or who had associated ophthalmologic or systemic risk factors.Item Efficacy of topical lodoxamide vs sodium cromoglycate and dexamethasone in rabbits with passive allergic conjunctivitisÖzturk, F; Güler, M; Ilker, SS; Sobaci, GA comparative study was conducted to evaluate the efficacy of lodoxamide tromethamine vs sodium cromoglycate and dexamethasone sodium phosphate in experimental allergic conjunctivitis in 45 rabbit eyes. The animals were randomly divided into 3 groups and treated with lodoxamide, cromoglycate, or dexamethasone. Blood-conjunctival permeability index and the weight of the conjunctiva were used to quantify the ocular inflammatory reaction. Lodoxamide was more effective than sodium cromoglycate but not dexamethasone in the treatment of acute allergic conjunctivitis.Item Penetration of topical and oral ofloxacin into the aqueous and vitreous humor of inflamed rabbit eyesÖztürk, F; Kurt, E; Inan, ÜÜ; Kortunay, S; Ilker, SS; Basci, NE; Bozkurt, APurpose: This study aimed to investigate the penetration of topical and oral ofloxacin into aqueous humor and vitreous humor in post-traumatic endophthalmitis model in rabbits. Methods: A standardized intraocular infection after penetrating injury was made in the right eyes of 16 rabbits. Intraocular infection was induced by intravitreal injection of a suspension of Staphylococcus aureus. The intact left eyes were maintained as controls. The animals were divided randomly into two groups. (1) In the topical group, two drops of offloxacin 0.3% eyedrops were instilled to both eyes every 30 min for 4 h. (2) In the topical-oral group, two doses of 25 mg/kg of ofloxacin at 12-h intervals were given orally, then the protocol of the first group was applied. Aqueous and vitreous humor samples were taken 30 min after the last drop. Ofloxacin concentrations were measured by using HPLC. Results: Mean aqueous levels of ofloxacin in control eyes were: 3.25 +/- 2.55 mu g/ml in topical group, 4.58 +/- 5.39 mu g/ml in topical-oral group. Mean aqueous levels in inflamed eyes were: 5.21 +/- 4.55 mu g/ml in topical group, 10.34 +/- 8.88 mu g/ml in topical-oral group. Mean vitreous levels of ofloxacin in control eyes were: 0.17 +/- 0.07 mu g/ml in topical group, 1.30 +/- 1.23 mu g/ml in topical-oral group. Mean vitreous levels in inflamed eyes were: 0.35 +/- 0.22 mu g/ml in topical group, 3.48 +/- 2.69 mu g/ml in topical-oral group. There was no significant difference among the groups (P > 0.05), however. Conclusions: The result of this study suggests that oral supplementation of ofloxacin to topical instillation increased the ocular levels of ofloxacin in the post-traumatic endophthalmitis model. Mean drug concentrations in aqueous and vitreous humors were above the 90% minimum inhibitory concentrations (MIC90) for most of the common microorganisms causing endophthalmitis in all eyes, except in the vitreous humors of the intact eyes instilled topically. (C) 2000 Elsevier Science B.V. All rights reserved.Item Penetration of topical and oral ciprofloxacin into the aqueous and vitreous humor in inflamed eyesÖztürk, F; Kortunay, S; Kurt, E; Ilker, SS; Basci, NE; Bozkurt, APurpose:To assess the aqueous and vitreous penetration of ciprofloxacin after topical and combined topical and oral administration and investigate the effects of inflammation on drug penetration. Methods: A standardized penetrating injury was made in the right eyes of 16 rabbits. Intraocular inflammation was induced by intravitreal injection of a suspension of Staphylococcus aureus in these eyes. The animals were divided into two groups according to treatment methodology: topical and topical-oral. The intact left eyes of the animals were maintained as controls. In the topical treatment group, two drops of ciprofloxacin 0.3% were instilled to both eyes every 30 minutes for 4 hours. In the topical-oral treatment group, animals were given two oral 40 mg/kg doses of ciprofloxacin at 12-hour intervals. After the last oral dose, the protocol of the topical group was applied to these eyes. Half an hour after the last drop, 100-muL samples were taken from aqueous and vitreous humor of ail eyes. Drug concentrations were measured using high-pressure liquid chromatography. Results: Mean aqueous levels of ciprofloxacin in control eyes were 2.31 mug/mL (range, 1.02-6.27 mug/ml) in the topical group and 5.88 mug/mL (1.52-17.81) in the topical-oral group. Mean aqueous levels in inflamed eyes were 7.36 mug/mL (2.34-17.15) in the topical group and 14.43 mug/mL (2.18-18.66) in the topical-oral group. Mean vitreous levels in control eyes were 0.77 mug/mL (0.09-1.93) in the topical group and 1.01 mug/mL(0.49-1.57) in the topical-oral group. Mean vitreous levels in inflamed eyes were 0.95 mug/mL (0.18-1.27) in the topical group and 1.98 mug/mL (0.51-3.34) in the topical-oral group. There was no significant difference among the groups (P > 0.05). Mean aqueous levels in all eyes and mean vitreous levels in the combined topical and oral group of inflamed eyes were above the 90% minimum inhibitory concentration for most of the common microorganisms causing endophthalmitis. Conclusion: There is an increase in both aqueous and Vitreous humor concentrations with inflammation and with oral and topical administrations, as opposed to topical only, of ciprofloxacin, Using oral as well as topical treatment may be a beneficial method of antibiotic prophylaxis in ocular trauma once a patient has received intravenous or intravitreal therapy.Item Ofloxacin levels after intravitreal injection -: Effects of trauma and inflammationÖztürk, F; Kortunay, S; Kurt, E; Inan, ÜÜ; Ilker, SS; Basci, NE; Bozkurt, A; Kayaalp, SOPurpose: This study was carried out to get an insight into the ofloxacin elimination after intravitreal injection in rabbits. We also studied the effects of trauma and inflammation on the vitreous ofloxacin levels after intravitreal injection of ofloxacin. Methods: A penetrating eye injury in the right eye was inflicted on 24 rabbits and another 12 animals were used as control. A standardized intraocular inflammation was induced by intravit-real injection of a suspension of Staphylococcus aureus in half of the traumatized eyes. Ofloxacin (200 mu g/0.1 ml) was injected into the midvitreous cavity of both traumatized and control right eyes, and samples were obtained at 2, 8, 24 and 48 h after injection. Drug concentrations were measured using high-pressure liquid chromatography analysis. Results: Vitreous levels of ofloxacin were above the MIC90 at 2 and 8 h in all groups for most of the common microorganisms causing endophthalmitis and also at 24 h in traumatized-infected eyes. At the second hour, the mean vitreous concentrations of ofloxacin both in traumatized and traumatized infected eyes were lower than that in the control eyes (p < 0.05). At 8 h, the mean vitreous concentrations of ofloxacin in the traumatized and in the traumatized-infected eyes were higher than that in the control eyes (p < 0.05). At 24 h, the mean ofloxacin concentration was higher in the traumatized-infected eyes than that in control (p < 0.01) and traumatized eyes (p < 0.05), and also higher in the traumatized eyes than that in the control eyes (p < 0.05). The mean ofloxacin concentrations in the traumatized and traumatized-infected eyes were significantly higher (p < 0.01) than those in the controls at 48 h. The elimination half-life of ofloxacin in the control eyes was 5.65 h and trauma and inflammation prolonged the half-life to 9.47 and 9.72 h, respectively. Conclusion: Clearance of ofloxacin is fast and appears to be reduced by trauma and inflammation. Therapeutic drug levels in traumatized-infected eyes were maintained up to 24 h. This may be an important pharmacokinetic advantage in treating endophthalmitis unless the dose used has local toxicity and allows a longer dose interval when the dose is repeated.Item The effect of long-term use and inflammation on the ocular penetration of topical ofloxacinÖztürk, F; Kortunay, S; Kurt, E; Inan, ÜÜ; Ilker, SS; Basci, N; Bozkurt, APurpose. To study the,penetration of ofloxacin into the aqueous and vitreous humors after long-term topical administration and to investigate the effects of inflammation on drug penetration in rabbits. Methods. A standardized model of intraocular infection after penetrating injury was achieved in the right eyes of 16 rabbits. The animals were randomly and equally-divided into two groups. The intact left eyes of the groups were maintained as the control. Ofloxacin eyedrops (0.3%) were instilled into all eyes at a frequency of 2 drops every hour for 7 hours in the first group and for 14 hours in the second group. Half an hour after the last drop, samples of the aqueous and vitreous humors were taken and ofloxacin concentrations were measured by using HPLC. Results. The mean aqueous humor concentrations of ofloxacin in control eyes after 7:and 14 hours of instillation were: 1.45 +/- 0.93 mu g/ml and 2.48 +/- 0.33 mu g/ml, respectively; those in infected eyes 2.35 +/- 1.84 mu g/ml and 3.49 +/- 1.47 mu g/ml, respectively. However the differences among the groups were not significant (p > 0.05). The vitreous ofloxacin concentrations in the control eyes were similar after 7 and 14 hours of instillation (0.23 +/- 0.14 mu g/ml, 0.27 +/- 0.10 mu g/ml, respectively). In infected eyes, the mean vitreous ofloxacin concentration after 14 hour of instillation was significantly higher than that in control eyes (p < 0.05; 0.4 +/- 0.09 mu g/ml, 0.29 +/- 0.11 mu g/ml, respectively). The mean vitreous ofloxacin concentration in infected eyes after 14 hours instillation was not significantly higher than that after 7 hours instillation. Conclusions. Topical ofloxacin instillation for 7 or 14 hours yields aqueous concentrations above the MIC90 for common ocular pathogens. Prolonged application and the presence of inflammation increased the penetration of ofloxacin into the vitreous humor.Item Effects of trauma and infection on ciprofloxacin levels in the vitreous cavityÖztürk, F; Kortunay, S; Kurt, E; Ilker, SS; Inan, ÜÜ; Basci, NE; Bozkurt, A; Kayaalp, SOObjective: This study was designed to determine the effects of trauma and infection on vitreous ciprofloxacin levels after intravitreal injection of ciprofloxacin in rabbits. Methods: A penetrating injury was made in the right eyes of 24 rabbits, in the eyes of half of the traumatized animals, a standardized intraocular infection was induced by intravitreal injection of a suspension of Staphylococcus aureus. The intact left eyes of the traumatized group were maintained as controls. Ciprofloxacin (200 mug/0.1 mL) was injected into the midvitreous cavity of both eyes in all animals and samples were obtained at 2, 8, 24, and 48 hours after injection. Drug concentrations were measured using high-pressure liquid chromatography analysis. Results: At the second hour, the mean Vitreous concentration of ciprofloxacin in the traumatized eyes was lower than that in control eyes (P < 0.05). The mean ciprofloxacin concentrations were significantly higher (P < 0.05) in the traumatized-infected eyes than were those in control or traumatized eyes at 24 and 48 hours. The elimination half-life of ciprofloxacin in control and traumatized eyes was 6.02 hours and 5.02 hours, respectively, and infection prolonged the half-life to 15.06 hours. Vitreous levels of ciprofloxacin were above the minimum inhibitory concentration (MIC90) for most of the common microorganisms causing endophthalmitis in all groups at 2 and 8 hours, but also at 24 and 48 hours in traumatized-infected eyes. Conclusion: Infection appears to decrease the clearance of ciprofloxacin. Therapeutic drug levels in traumatized-infected eyes were maintained up to 48 hours. Assuming that the animal model used may have a predictive Value for the drug elimination in traumatized-infected human eyes, we suggest that local administration of ciprofloxacin every 2 days may be relevant from the therapeutic perspective.Item Evaluation of Subclinical Multiple Sclerosis Patients Using Pattern Visual Evoked Potentials and Visual Field TestBilgin, S; Ilker, SS; Çavdar, E; Türker, IObjectives: The aim of this study was to evaluate subclinical multiple sclerosis (MS) patients with normal visual acuity using pattern visual evoked potentials (PVEP) test and central 30-2 threshold visual field (VF) test. Materials and Methods: A total of 60 patients, 30 of which had a definitive MS diagnosis and 30 who were healthy volunteers, were included in the study. The participants were divided into the following three groups: Group 1 -optic neuritis (+) MS patients, Group 2 -optic neuritis (-) MS patients, and Group 3 - control group. Using white on white perimetry, SITA FAST central 30-2 threshold VF tests and 1 degrees-0.3 degrees PVEP measurements were performed. MD, PSD, p100 latency (ms), p100 amplitude (mu V), and central 0-10 degrees, 0-20 degrees, 0-30 degrees, 10-20 degrees, 10-30 degrees, 20-30 degrees retina sensitivities (db) were evaluated in all groups. Results: There was a significant difference in all parameters between Group 1 and Group 3 (p<0.05). There was a significant difference in p100 latency 1 degrees-0.3 degrees, p100 amplitude 0.3 degrees, central 0-30 degrees, 10-30 degrees, 20-30 degrees between Group 2 and Group 3 (p<0.05). There was no significant difference in the parameters except for p100 amplitude 1 degrees between Group 1 and Group 2 (p>0.05). Conclusion: The evaluation of PVEP and central 30 degrees VF can be used to monitor disease prognosis in subclinical MS patients.Item Antineovascular effect of α-interferon on corneal neovascularization in ratsÖztürk, F; Sobaci, G; Ilker, SS; Can, CClinical and histologic effects of topical recombinant a-interferon (IFN) systemic IFN topical dexamethasone, and dexamethasone plus topical IFN on corneal neovascularization in response to silver nitrate cauterization were investigated in 110 eyes of 60 Wistar rats. The eyes were evaluated according to tire burn stimulus, neovascularization, and histologic inflammation grades 5 days after cauterization. Antineovascular effects of topical and systemic IFN were significantly greater than a placebo but less than dexamethasone alone or in combination with IFN.Item Chiasmal decussation in tilted disc syndrome PVER in tilted discÖztürk, F; Kurt, E; Yoldas, T; Ilker, SS; Inan, ÜÜThe tilted disc syndrome is a benign congenital abnormality of the optic nerve head. Since it can be confused with papilledema and chiasmal lesions, differential diagnosis is important. The tilting anomaly may be associated with other abnormalities along the optic nerve. Visual field defects may be similar to those in chiasmal lesions. In order to determine whether the normal crossover of nerve fibers at the chiasm is altered, the crossed and the uncrossed fibers were investigated using the pattern visual evoked responses (PVER) test. Thirty-four eyes of 17 patients diagnosed with tilted disc syndrome were evaluated for refraction, keratometry, color vision with Ishihara, visual field, and PVER. The presence of abnormal nerve fiber decussation was determined by recording PVER from the electrodes mounted on the scalp of both hemispheres. The amplitude and latency differences between the 'crossed' and 'uncrossed' fibers were not statistically significant (p>0.05). As a result, the tilting abnormality of papilla was found to be without chiasmal abnormal decussation.Item Comparison of Icare Pro Tonometry and Icare one Tonometry Measurements in Healthy EyesMayali, H; Sarigül, Ç; Kurt, E; Kayikçioglu, ÖR; Ilker, SSObjectives: To compare intraocular pressure (IOP) measurements obtained with the Icare Pro tonometer used in clinical practice and the Icare One self-tonometer. Materials and Methods: Fifty-two eyes of 52 healthy, right-handed individuals with no prior intraocular surgery or ocular trauma, structural ocular pathology, or systemic disease were evaluated. IOP was first measured using the Icare Pro tonometer. The participants were then told how to use the Icare One tonometer and asked to measure their own IOP The results were analyzed statistically using SPSS v.24. Results: Of the 52 healthy participants, 16 (30.7%) were male and 36 (69.3%) were female. Their mean age was 31.6 +/- 6.3 (23-47) years. Mean IOP measured with the Icare Pro was 17.10 +/- 6.2 (11.5-25.2) mmHg, and the mean self-measured IOP with Icare One was 14.01 +/- 3.4 (7-24) mmHg. When the two methods were compared using Levene's t-test, there was a significant mean difference of -3.08 +/- 0.6 (95% confidence interval: -4.39 -1.78; p<0.001). Conclusion: In this study, there was a significant difference between the IOP measurements we made using the Icare Pro and the participants' self-measured IOP using the Icare One, with the latter being relatively lower. This may be related to the fact that the participants were unfamiliar with using the Icare One. Although the Icare One is a promising tool for glaucoma patients to self-monitor their IOP, further studies are needed.Item A comparative study of type 1 neovascularization: Neovascular age-related macular degeneration versus pachychoroid neovasculopathyAltinisik, M; Kurt, E; Sonmezer, P; Kayikcioglu, O; Ilker, SSPurpose: This study aimed to compare type 1 choroidal neovascularization (CNV) characteristics in eyes with pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA). Methods: Treatment naive 23 eyes of 23 patients with PNV and 24 eyes of 24 patients with nAMD were evaluated. The height of pigment epithelial detachment (PED) and the central macular thickness were determined. OCTA sensitivity, CNV area, morphological patterns, and retinal superficial capillary plexus vessel density (SCP-VD) values were compared. The frequency of quiescent CNV, subretinal hyperreflective exudation (SHE), subretinal/intraretinal fluid, serous PED, double-layer sign (DLS), and pachyvessels were noted. Results: CNV was detected on OCTA in 83.3% of nAMD eyes and 91.3% of PNV eyes (p = 0.66). Indistinct pattern was more common (74% vs 50%) and the CNV area (mm(2)) was smaller in PNV (0.77 +/- 0.54 vs 1.57 +/- 1.43) but did not reach significant levels (p = 0.27 and 0.33 respectively). SCP-VD was similar between the groups (p = 0.38). Statistically significant differences were found between groups in age and subfoveal choroidal thickness (p < 0.05). DLS and pachyvessels were found to be more frequently in PNV (p < 0.05). However, both groups had similar rates of quiescent CNV, SHE, subretinal/intraretinal fluid, and serous PED (p > 0.05). Conclusion: Morphological features, area, and activation findings of type 1 CNV may play a limited role in differentiating nAMD and PNV cases.Item Corneal endothelial damage in phacoemulsification using an anterior chamber maintainer compared with using an ophthalmic viscosurgical deviceMayali, H; Baser, EF; Kurt, E; Ilker, SSPurpose: To compare the effects of phacoemulsification surgery (PE) using an anterior chamber maintainer (ACM) and conventional PE using an ophthalmic viscosurgical device (OVD) on corneal endothelial cells. Setting: Department of Ophthalmology, Celal Bayar University, Manisa, Turkey. Design: Prospective randomized controlled trial. Methods: Eyes in the OVD group (n = 50) underwent conventional PE, whereas eyes in the ACM group (n = 50) underwent PE using an ACM. Endothelial cell density (ECD), coefficient of variation (CV), hexagonality (HEX), and noncontact central corneal thickness (CCT) measurements were performed by specular microscopy before and at 1 month, 3 months, and 6 months after PE. Results: This study included 100 eyes of 97 patients undergoing PE. The mean age was 64.7 ? 10.6 years in the OVD group, 64.0 ? 12.6 years in the ACM group (P > .05). The groups did not differ significantly in preoperative ECD, CV, HEX, and CCT or total PE time (P > .05 for all). ECD was significantly lower in the ACM group compared with the OVD group at postoperative 1 month, 3 months, and 6 months (P = .002, P = .002, and P = .001, respectively). Similarly, ECD loss compared with preoperative value was greater in the ACM group at all postoperative timepoints (P = .003, P = .001, and P = .001, respectively). CV increased and HEX decreased in both groups postoperatively (P > .05 for both). CCT showed a transient increase of less than 10 mm at postoperative 1 month in both groups (P = .296). Conclusions: PE with ACM was associated with greater corneal ECD loss compared with conventional PE. ACM should not be used during PE in patients with limited corneal endothelial reserve. J Cataract Refract Surg 2021; 47:612?617 Copyright ? 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRSItem Efficacy of eye patching for corneal healing after removal of corneal foreign bodyKurt, E; Öztürk, F; Inan, ÜÜ; Emiroglu, ML; Ilker, SSStandard treatment of corneal epithelial loss includes an eye patch with antibiotic ointment. We compared the efficacy of eye patching with no eye patching on corneal epithelial healing of 84 patients after foreign body removal. Since no significant difference between two groups for corneal healing was found, antibiotic treatment alone may he sufficient for treatment of corneal epithelial loss after foreign body removal.Item Idiopathic Inflammatory Neuroretinitis Simulating Optic Nerve Sheath Dural EctasiaIlker, SS; Seymenoglu, G; Tarhan, S; Uzun, Ö; Sencan, SWe report a case of a 32-year-old female patient who presented with decreased vision on both eyes and headache. In fundus examination, both eyes had elevation of the optic disc and star shaped hard exudates in the macula. Magnetic resonance imaging was completely normal except the saccular dilatation of bilateral optic nerve sheath. The patient was treated with oral steroids following high-dose intravenous methylprednisolone. She displayed good anatomical and functional results during the follow-up. This case raises the possibility that optic nerve sheath enlargement, probably induced by an idiopathic inflammatory optic neuritis, may simulate dural ectasia of the optic nerve sheath.Item Evaluation of the Effect of Body Position on Intraocular Pressure Measured with Rebound TonometerMayali, H; Tekin, B; Kayikçioglu, ÖR; Kurt, E; Ilker, SSObjectives: It is important to determine variables that influence intraocular pressure (IOP) measurement. This study aimed to evaluate the effect of body position on IOP. Materials and Methods: The study included 52 right eyes of 52 patients who presented to the ophthalmology department of our hospital and had no ocular disease except refractive errors. IOP was measured with an Icare PRO tonometer while patients were in sitting, standing, and supine positions, with intervals of 10 minutes between the positions. Correlations between the results were evaluated using Spearman's correlation analysis and Wilcoxon tests. Results: Thirty-six of the 52 patients were female, 16 were male. Mean age was 31.65 +/- 6.30 (23-47) years. Mean IOP values in the sitting, standing, and lying positions were 17.76 +/- 3.41 (12.70-25.60) mmHg, 17.10 +/- 3.27 (11.50-25.20) mmHg, and 18.46 +/- 4.67 (10.50-29.40) mmHg, respectively. There were no statistically significant differences between measurements taken in the different positions (p=0.112, p=0.472, p=0.071). We observed that there was no relationship between age and body position (p>0.45, p>0.79, p>0.77) or between gender and position (p>0.59, p>0.69, p>0.54). Conclusion: Gender and age had no effect on IOP measured in different body positions. There were also no significant differences between IOP values measured in the different positions. Therefore, we believe the portable Icare PRO tonometer can be used for patients who are confined to bed and will provide IOP measurements that are concordant with values obtained while sitting.