Browsing by Author "Inan U."

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    Changes in the intraocular pressure during anaesthesia with sevofluran and propofol; [Propofol ve sevofluran anestezilerinde gozici basinci degisikliklerinin karsilastirilmasi]
    (1997) Ozturk F.; Tekin I.; Kurt E.; Luleci N.; Inan U.; Alincak H.; Tutan A.
    Variations in intraocular pressure during anaesthesia were studied prospectively in two groups of 20 patients selected randomly. The first group received sevoflurane and the second group received IV propofol. Intraocular pressure, heart rate, arterial pressure and oxygen saturation were measured before and after induction of anaesthesia and following vecuronium. Compared with baseline values, the decrease in intraocular pressure were similar (p>0.05) and statistically significant (p<0.05) in two groups. Haemodynamic control were better in sevoflurane group. In ophthalmic operations when intraocular pressure control were required, both anaestetic agents seem to be proper.
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    A comparison of two sedation methods for elective cataract surgery; [Katarakt cerrahisinde lokal anestezi oncesinde iki farkli sedasyon yonteminin karsilastirilmasi]
    (1998) Tekin I.; Ozturk F.; Erincler T.; Luleci N.; Alincak H.; Kurt E.; Inan U.
    The aim of this study was; to compare two different ways of sedation for elective cataract surgery. 30 patients (in ASA I-II-III classes and 18-65 years old), undergoing to elective cataract surgery were divided in two groups, each of them consisted from 15 patients. In group I sedation was performed with 1 mg/kg propofol IV and in the second group with a combination of 0.07 mg/kg droperidol and 1 μg/kg fentanil IV. Intraocular pressure (IOP) was measured; heart rate (HR), mean arterial blood pressure (MAP), SpO2, respiratory rate (RR) and sedation scores (SS) were noted before (T1), 5 minutes after sedation (T2), and at the end of the operation (T3). Just after the operation side effects, amnesia and general agreement of the patients were asked. Between two groups the IOP and MAP values were not significantly different before sedation (p>0.05). A significant fall of both values were noted after sedation in both groups. At the end of the operation the values were higher in the second group (p<0.05). The sedation scores were not different between two groups before the application of sedative drugs. After this application significantly deeper sedation was noted in the first group (p<0.05). In the second group the sedation scores were not significantly different before, after the application and at the end of the operation (p>0.05). In the first group, the sedation scores were higher at the end of the operation if compared with values that noted after the application of propofol. The agreement of the patients to this method were better in the first group. As a result, it can be said that; sedation with the combination of droperidol and fentanyl for elective cataract surgery in also possible, but low doses of propofol are better for this purpose.
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    The effect of propolis extract in experimental chemical corneal injury
    (S. Karger AG, 2000) Öztürk F.; Kurt E.; Çerçi M.; Emiroǧlu L.; Inan U.; Türker M.; Ilker S.
    Purpose: To investigate the effect of propolis, a natural resin produced by honeybees, in the treatment of alkali-injured rabbit eyes. Method: A corneal alkali burn was induced by applying filter paper immersed in 1 N NaOH on the central axis of the right corneas of 24 rabbits for 30 s. The animals were divided into three treatment groups: group 1 (control) was given 0.3% tobramycin and phosphate-buffered solution; group 2 was treated with antibiotic coverage and topical 1% ethanolic extract of propolis; group 3 received antibiotic coverage and topical 1% dexamethasone. The dexamethasone-treated group was maintained as the positive control. Drugs were instilled 4 times a day for 7 days. The corneal inflammation was evaluated by calculating the average inflammatory index obtained from clinical observation of the ciliary hyperemia, central and peripheral corneal edema at 24 h, 48 h, on day 5 and day 7, before sacrificing the animals. Then, the corneas underwent routine histological examination. Results: The effects of dexamethasone and propolis on healing of injured corneas were similar (p > 0.05) and significantly better than controls at 24 h (p < 0.01, p < 0.05, respectively), and on day 7 (p < 0.05) with respect to the inflammatory index. On histological observation, inflammatory cell infiltration was lower as compared to control in both the dexamethasone and propolis groups (p < 0.001) and similar with each other (p > 0.05). Conclusions: Our study shows that propolis has an anti-inflammatory effect comparable to dexamethasone in chemical corneal injury. Copyright (C) 2000 S. Karger AG, Basel.