MCBÜ Açıkerişim Sistemi :: Browsing by Author "Köktürk N."

Browsing by Author "Köktürk N."

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Reliability and validity of Turkish version of COPD Assessment Test; [KOAH deǧerlendirme testinin Türkçe geçerlilik ve güvenilirliǧi]
(Ankara University, 2012) Yorgancioǧlu A.; Polatli M.; Aydemir Ö.; Yilmaz Demirci N.; Kirkil G.; Nayci Atiş S.; Köktürk N.; Uysal A.; Akdemir S.E.; Özgür E.S.; Günakan G.
Introduction: This study is aimed to evaluate the reliability and validity of the Turkish version of chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) in seven centers. Materials and Methods: 321 patients between 4-75 years of age, diagnosed and staged by Global Initiative for Obstructive Lung Disease (GOLD) 2011 criteria were included. The Breathlessness, Cough, Sputum scale (BCSS), mMRC (Modified Medical Research Council) dyspnea index, St. George Respiratory Questionnaire (SGRQ), CAT and Short Form-36 (SF-36) were used concurrently. In the statistical analyses, internal consistency, item-total score correlation, explorative factor analysis, correlation with other scales were calculated. Results: The mean age was 62.4 ± 8.9 years and 89.7% of the patients were male (n= 288). Mean FEV 1% was 51.9 ± 19.2 and most of the patients were in Stage 3. CAT total score was 17.8 ± 9.5. In the internal consistency, Cronbach alpha coefficient was found as 0.9116 and item-total score correlation coefficients were between 0.62-0.79 and all were statistically significant (p< 0.0001). The correlation of the test-retest score calculated after two weeks with the initial score was 0.96 (p< 0.0001). In the structural validity, factor analysis with principle component analysis and varimax rotation was performed. One factor solution was achieved with eigenvalue of 4.956 and it represented 61.9% of the total variance. All the items were contained in the factor and the factor loads were between 0.71-0.85. The correlation coefficients of CAT with other indexes were moderate to good. The discrimination of CAT among disease stages has been shown to be significant (p< 0.0001) and a significant correlation was found with pulmonary function tests (p< 0.0001). Conclusion: It is demonstrated The Turkish version of COPD Assessment Tool is reliable and valid.
Validity and reliability of Turkish version of St. George's respiratory questionnaire; [St. George solunum anketinin Türkçe geçerlilik ve güvenilirliǧi]
(2013) Polatli M.; Yorgancioǧlu A.; Aydemir Ö.; Yilmaz Demirci N.; Kirkil G.; Atiş Nayci S.; Köktürk N.; Uysal A.; Akdemir S.E.; Özgür E.S.; Günakan G.
Introduction: The importance of the evaluation of health status in chronic obstructive pulmonary disease (COPD) is recently highlighted in many studies. In this study, we aimed to test the validity and reliability of the Turkish version of St. George Respiratory Questionnaire (SGRQ). Materials and Methods: The study was conducted in seven centers in Turkey. Three hundred and twenty one COPD patients (40-75 years) were included to the study. Turkish versions of breathlessness, Cough, and Sputum Scale (BCSS), mMRC (Modified Medical Research Council) dyspnea scale, SGRQ, COPD assessment test (CAT) and Short Form Health Survey (SF-36) were carried out to the patients. The statistical analysis of SGRQ was performed by using the coefficient of internal consistency, discriminative analysis for different stages and the correlation with the other scales. Results: The mean age was 62.4 ± 8.9 years and the mean FEV1 was 51.9 ± 19.2% pred. The coefficient of internal consistency (Cronbach alpha) was 0.8815. The correlation between the total score measured initially and that obtained two weeks later was found to be highly significant (r= 0.90, p< 0.0001). According the results of validation of both total score and the components of SGRQ, the correlation between the total score of SGRQ and CAT was 0.782 (p< 0.0001), SGRQ and SF- 36 was between -0.481 ile -0.819 (p< 0.0001). The total and component scores were able to discriminate different disease stages and a significant correlation was found to be with pulmonary function tests. Conclusion: SGRQ Turkish version is a reliable and valid assessment tool for COPD patients in clinical practice.
Evaluation of asthma and COPD awareness in primary care doctors in Turkey; [Türkiye’de birinci basamak hekimlerinde astım ve KOAH farkındalığının değerlendirilmesi]
(Ankara University, 2016) Ersu R.; Bingöl Karakoç G.; Yildiz F.; Köktürk N.; Mungan D.; Ekinci B.; Gemicioğlu B.; Yorgancioğlu A.A.
Introduction: Chronic pulmonary diseases cause significant morbidity and mortality. However awareness about the risk factors, symptoms, diagnosis and traetment of these disorders is low among patients and health care providers. Our aim was to evaluate the awareness of asthma and chronic obstructive pulmonary disease among primary care doctors. This study was performed by the national Global Alliance Against Chronic Respiratory Diseases programme. Material and Methods: Primary care doctors employed by the Ministry of Healthy were included to the study. Turkish Statistical Institute randomly selected 680 doctors. Questionnaires evaluating the awareness of asthma and COPD which were developed by the Turkish Thoracic Society COPD and asthma assemblies were completed online by these doctors. Results: 84% of the doctors described asthma as airway obstruction. Dyspnea was reported as the most common symptom of asthma (78.8%) and inspiratory rhonci was reported as the most common physical exam finding (42.3%). Around 50% of doctors thought impairment of pulmonary function tests (PFT) was important for diagnosis and evaluation of severity of asthma while 24.2% thought physical exam was more important. When treatment options were evaluated 87.6% chose inhaled treatment for asthma. COPD was described as bronchiectasis and chronic bronchitis by 9.1%, chronic bronchitis and emphysema by 61.6%, chronic bronchitis and asthma by 22.2% and asthma and emphysema by 7.1%. 1.2% of the doctors did not consider cigarette smoking as a risk factor for COPD. PFT was recommended for diagnosis by 83%. Most correctly differentiated asthma and COPD. Bronchodilators were the first choice for COPD by 72.5%. Conclusion: Awareness is low for asthma and COPD among primary care doctors. Awareness should be raised among health care professionals for these diseases with high economical burden to improve outcome. © 2016, Ankara University. All rights reserved.
Assessing the knowledge in primary health care following an educational course structured in the context of gard chronic airway diseases national control program; [Türkiye kronik hava yolu hastalıkları önleme ve kontrol programı (GARD Türkiye) birinci basamakta çalışan hekim eğitimi bilgi değerlendirme sonuçları]
(Ankara University, 2017) Öner Erkekol F.; Köktürk N.; Mungan D.; Saçkesen C.; Önen Z.P.; Özkan S.; Balkan A.; Ergün P.; Kocabaş C.N.; Baran Aksakal N.; Ekıcı B.; Özkan Altunay Z.; Gemıcıoğlu B.; Yorgancıoğlu A.
Introduction: Chronic obstructive pulmonary diseases are common causes of disease in the community and account for considerable percent of the caseload in primary health care facilities. For this reason, it is important to question and improve the knowledge of primary health care physicians. This study is designed to assess the level of knowledge for bronchial asthma and COPD of the primary healthcare physicians, both before and immediately after an educational course structured in the context of GARD Chronic Airway Diseases National Control Program. Materials and Methods: The participating physicians attended an intensive educational course on asthma and COPD. Twenty five item questionnaires for asthma and COPD were administered to the participants both before and immediately after the end of the course. Contribution of education to the level of knowledge was investigated by comparing the percentages of the correct answers in the pre-and post-test. Results: From 11 different cities, 1817 and 1788 primary health care physician were attended to the asthma and COPD educations, respectively. The accuracy rate of ≥ 75% was obtained from only 4 questions in pre-test asthma questionnaire. On the contrary, in 15 questions the accuracy rate was < 50%. The mean accuracy rate for the whole asthma test was 45.8%, and this rate raised to 69.6% after education course. The accuracy rate of ≥ 75% could not be obtained from any of the questions in pre-test COPD questionnaire. On the contrary, in 19 questions the accuracy rate was < 50%. The mean accuracy rate for the whole asthma test was 42.0%, and this rate raised to 71.3% after education course. Conclusion: It has been shown that, in primary care settings, the level of knowledge in asthma and COPD should be enhanced and that this increase can be achieved with an education course. © 2017, Ankara University. All rights reserved.
Asthma in the context of global alliance against respiratory diseases (GARD) in Turkey
(AME Publishing Company, 2018) Yorgancioğlu A.; Gemicioglu B.; Ekinci B.; özkan Z.; Bayram H.; Ergan B.; Ersu R.; Kocabaş A.; Köktürk N.
[No abstract available]
COVID-19 pandemic and the global perspective of turkish thoracic society
(AVES, 2020) Köktürk N.; İtil B.O.; Altınışık G.; Adıgüzel N.; Akgün M.; Akyıldız L.; Altın S.; Arıkan H.; Ateş G.; Ay P.; Aykaç N.; Babayiğit C.; Bostan P.; Cinel G.; Çalışır H.C.; Çelik P.; Çetinkaya P.D.; Dağlı E.; Demir A.U.; Demir C.; Dikensoy Ö.; Edis E.Ç.; Elbek O.; Erdinç M.; Ergan B.; Eyüboğlu A.F.Ö.; Gemicioğlu B.; Göksel T.; Gülhan E.; Gültekin Ö.; Gürkan C.G.; Gürgün A.; Havlucu Y.; Başoğlu O.K.; Karakurt S.; Karakurt Z.; Kılınç O.; Kocabaş A.; Kul S.; Müsellim B.; Naycı S.; Özkan M.; Pınarer Ö.; Saltürk C.; Sandal A.; Sayıner A.; Şen E.; Şimşek G.Ö.; Karadağ B.T.; Akyıl F.T.; Töreyin Z.N.; Uçan E.S.; Küçük F.Ç.U.; Varol A.; Yasin Y.; Yıldız T.; Arzu Yorgancıoğlu A.; Bayram H.
It has been more than 3 months now since the first case of COVID-19 was reported in Turkey. Globally, the number of confirmed cases and deaths reached 9,653,048 and 491,128 respectively, as reported by 216 countries by June 27, 2020. Turkey had 1,396 new cases, 194,511 total cases, and 5,065 deaths by the same date. From the first case until today, the Turkish Thoracic Society (TTS) has been very proactive in educating doctors, increasing public awareness, undertaking academic studies, and assisting with public health policies. In the present report, social, academic, and management perspectives of the pandemic are presented under appropriate subtitles. During this critical public health crisis, TTS has once again demonstrated its readiness and constructive stance by supporting public health, healthcare workers, and the environment. This review summarizes the perspective of TTS on each aspect of the COVID-19 pandemic and casts light on its contributions. © 2020 by Turkish Thoracic Society.
Attitude and Practice Toward Use of Cigarettes and Electronic Cigarettes Among Pregnant Women: A Questionnaire-Based Survey
(AVES, 2022) Yıldırım E.; Duru S.; Sevim T.; Topçu F.; Gemicioğlu B.; Özmen İ.; Ocaklı B.; Tuncay E.; Altınöz H.; Akpak Y.K.; Çelik P.; Varol Y.; Polat G.; Özkan S.; Dursunoğlu N.; Kılıç D.; Gülhan P.Y.; Diken Ö.E.; Çetinkaya P.D.; Yorgancıoğlu A.; Selçuk N.T.; Yıldız F.; Atacağ T.; Niksarlioğlu E.Y.; Uzaslan E.; Köktürk N.
OBJECTIVE: This study aimed to evaluate attitude and practice toward use of regular tobacco cigarettes and electronic cigarettes among pregnant women. MATERIAL AND METHODS: A total of 1123 pregnant women participated on a voluntary basis in this questionnaire survey. Maternal charac-teristics, cigarette consumption parameters, and personal opinions regarding the adverse effects of smoking during pregnancy were evaluated. RESULTS: Active smokers composed 12.4% (9.4%: regular tobacco cigarettes, 3.0%: electronic cigarettes) of the study population. Smoking during the current pregnancy, particularly via regular tobacco cigarettes, was more likely for women with smoking during previous pregnancies (56.0% vs. 7.8%, P <.001), previous history of low birth weight infant delivery (16.1% vs. 8.6%, P =.013), premature delivery (16.7% vs. 7.0%, P <.001), and stillbirth (22.8% vs. 11.7%, P =.002). The presence versus absence of smoking during pregnancy was associated with a lower likelihood of being a housewife (70.5% vs. 80.5%, P =.010) and a higher likelihood of having an actively smoking mother (25.9% vs. 11.2%, P <.001) or partner (65.7% vs. 46.9%, P <.001). Regular tobacco cigarette users considered electronic cigarettes to have a higher risk of adverse impacts (11.1% vs. 2.9%, P =.012), while electronic cigarette users considered regular cigarettes to have a higher risk of nicotine exposure (55.9% vs. 13.0%, P <.001). CONCLUSION: Our findings indicate being employed, having an actively smoking mother or partner, as well as smoking in previous pregnancies, to be the risk factors for increased likelihood of smoking during pregnancy. © 2022, AVES. All rights reserved.
Clinical Course of Coronavirus disease 2019 C-19 in Patients with Bronchiectasis
(AVES, 2024) Edis E.Ç.; Çilli A.; Kızılırmak D.; Coşkun A.Ş.; Sayıner A.; Çiçek S.; Gülmez İ.; Ağca M.Ç.; Çağlayan B.; Özçelik N.; Köktürk N.; Ocaklı B.; Uçan E.S.; Günlüoğlu G.; Niksarlıoğlu Y.; Zamani A.; Berk S.; Barış S.A.; Başyiğit İ.; Gülhan P.Y.; Kabak M.; Çolak M.; Toprak O.B.; Berk H.; Oğuzülgen K.; Demirdöğen E.; Eyüboğlu F.Ö.; Havlucu Y.; Babayiğit C.
OBJECTIVE: Coronavirus disease 2019 (COVID-19) has affected the whole world and caused the death of more than 6 million people. The disease has been observed to have a more severe course in patients with chronic lung diseases. There are limited data regarding COVID-19 in patients with bronchiectasis. The aim of this article is to investigate the course of COVID-19 and factors affecting the clinical outcome in patients with bronchiectasis. MATERIAL AND METHODS: This study was conducted using the Turkish Adult Bronchiectasis Database (TEBVEB) to which 25 centers in Türkiye contributed between March 2019 and January 2022. The database consisted of 1035 patients, and COVID-19-related data were recorded for 606 patients. RESULTS: One hundred nineteen (19.6%) of the bronchiectasis patients (64 female, mean age 57.3 ± 13.9) had COVID-19. Patients with bronchiectasis who developed COVID-19 more frequently had other comorbidities (P = .034). They also more frequently had cystic bron-chiectasis (P = .009) and their Bronchiectasis Severity Index was significantly higher (P = .019). Eighty-two (68.9%) of the patients who had COVID-19 were followed up in the outpatient clinic, 27 (22.7%) in the inpatient ward and 10 (8.4%) patients in the intensive care unit. There tended to be a higher percentage of males among patients admitted to the hospital (P = .073); similarly, the mean age of the patients admitted to the hospital was also higher (60.8 vs 55.8 years for the outpatients), but these differences did not reach statistical significance (P = .071). CONCLUSION: In conclusion, this study showed that severe bronchiectasis, presence of cystic bronchiectasis and worse Bronchiectasis Severity Index are associated with the development of COVID-19, but not with the severity of infection. © 2024, AVES. All rights reserved.
Bronchiectasis in Türkiye: Data from a Multicenter Registry (Turkish Adult Bronchiectasis Database)
(Galenos Publishing House, 2024) Edis E.Ç.; Çilli A.; Kızılırmak D.; Coşkun A.Ş.; Güler N.; Çiçek S.; Sevinç C.; Ağca M.Ç.; Gülmez İ.; Çağlayan B.; Kabak M.; Niksarlıoğlu E.Y.Ö.; Köktürk N.; Sayıner A.
Background: Bronchiectasis is a chronic lung disease characterized by permanent bronchial wall dilatation. Although it has been known as an orphan disease, it has recently gained attention because of registry-based studies and drug research. Aims: We aimed to use a multicenter database to analyze and compare data regarding the etiology, associated comorbidities, microbiological characteristics, and preventive strategies of bronchiectasis in Türkiye to those of other countries. Study Design: A multicenter prospective cohort study. Methods: The multicenter, prospective cohort study was conducted between March 2019 and January 2022 using the Turkish Adult Bronchiectasis Database, in which 25 centers in Türkiye participated. Patients aged > 18 years who presented with respiratory symptoms such as cough, sputum, and dyspnea and were diagnosed with non-cystic fibrosis bronchiectasis using computed tomography were included in the study. Demographic information, etiologies, comorbidities, pulmonary functions, and microbiological, radiological, and clinical data were collected from the patients. Results: Of the 1,035 study participants, 518 (50%) were females. The mean age of the patients was 56.1 ± 16.1 years. The underlying etiology was detected in 565 (54.6%) patients. While postinfectious origin was the most common cause of bronchiectasis (39.5%), tuberculosis was identified in 11.3% of the patients. An additional comorbidity was detected in 688 (66.5%) patients. The most common comorbidity was cardiovascular disease, and chronic obstructive pulmonary disease (COPD) and bronchiectasis was identified in 19.5% of the patients. The most commonly detected microbiological agent was Pseudomonas aeruginosa (29.4%). Inhaled corticosteroids (ICS) were used in 70.1% of the patients, and the frequency of exacerbations in the last year was significantly higher in patients using ICS than in nonusers (p < 0.0001). Age [odds ratio (OR): 1.028; 95% confidence interval (CI): 1.005-1.051], cachexia (OR: 4.774; 95% CI: 2,054-11,097), high modified medical research council dyspnea scale score (OR: 1,952; 95% CI: 1,459-2,611), presence of chronic renal failure (OR: 4,172; 95% CI: 1,249-13,938) and use of inhaled steroids (OR: 2,587; 95% CI: 1,098-6,098) were significant risk factors for mortality. Mortality rates were higher in patients with COPD than in those with no COPD (21.7-9.1%, p = 0.016). Patients with bronchiectasis and COPD exhibited more frequent exacerbations, exacerbation-related hospitalizations, and hospitalization in the intensive care unit in the previous year than patients without COPD. Conclusion: This is the first multicenter study of bronchiectasis in Türkiye. The study results will provide important data that can guide the development of health policies in Türkiye on issues such as infection control, vaccination, and the unnecessary use of antibiotics and steroids. © Author(s).

Browsing by Author "Köktürk N."

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