Browsing by Author "Köse, MD"

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    Antioxidant, Antimicrobial, and Cytotoxic Activities of Condensate from Rf-Vacuum Timber Drying Process in the Forestry Industry
    Köse, MD; Uslu, ME; Bayraktar, O
    As the demand for dried timber has been increasing worldwide, drying of timbers is required to supply the demand in the manufacturing industries of furniture and other interior woodwork. During the drying process, some condensation will occur, resulting in liquids' emission, which requires disposal. In the liquid condensate, there are many substances at low concentrations that make their recovery uneconomic. After revealing the potential of the substances available in these condensates, biotechnological processes can be employed to produce high value-added products. This condensate contains tree sap, including proteins, enzymes, and many natural compounds such as terpenoids, alkaloids, phenolic compounds. Thus, it is considered that these natural compounds might be beneficial in pharmaceutical applications. Natural compounds such as phenolic compounds are bioactive substances that have antioxidant, antimicrobial, and cytotoxic activities. This study was aimed to characterize the condensate from the Rf-vacuum drying process of beech (Fagus sylvatica L.), walnut (Juglans regia L.), and restharrow (Onosis arvensis L.) in terms of antioxidant capacity, total phenol content, antimicrobial activity, and cytotoxicity. Obtained data revealed that condensates from the Rf-vacuum drying process inhibited the growth of both S. epidermidis and E. coli significantly.
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    Utilization of Eggshell Membrane and Olive Leaf Extract for the Preparation of Functional Materials
    Bayraktar, O; Galanakis, CM; Aldawoud, TMS; Ibrahim, SA; Köse, MD; Uslu, ME
    Eggshell membrane (ESM) is a natural proteinaceous by-product of the food industry, especially in the pasteurized egg industry, resulting in the availability of much discarded egg waste. In the literature, eggshell (ES) and ESM usage for their adsorbent properties to remove various organic and inorganic hazardous chemicals, especially from wastewater, has gained interest. In addition, agricultural (olive leaf) and food industry (eggshell and eggshell membrane) waste can together be valorized to produce value-added functional products. This study's objective was to evaluate the eggshell membrane's loading capacity for bioactive compounds obtained from olive leaf extract (OLE) in order to prepare functional biomaterial. In this study, waste eggshell membranes were used to adsorb the phenolic compounds from olive leaf extract to design functional biomaterials. Using the foam separation method, both separation of the eggshell membrane and adsorption of bioactive compounds to the eggshell membrane were achieved simultaneously. The characterization studies showed that OLE was successfully adsorbed to the eggshell membrane. Cytotoxicity and antimicrobial studies showed that prepared OLE-loaded membranes were functional materials with bioactive properties. In conclusion, ESM was determined as a promising protein in the production of functional antioxidative and antimicrobial food or dietary supplement after the adsorption of bioactive olive leaf polyphenols.