Browsing by Author "Kaplan Y."

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    The research of association between HBV prevalence and socioeconomical status after universal vaccination in children, in Manisa; [Manisa i̇lindeki çocuklarda kitlesel hepatit b aşilamasi sonrasi HBV Prevalansinin Sosyoekonomik Durumla İlişkisinin Araştirilmas?]
    (2010) Tosun S.; Deveci S.; Kaplan Y.; Kasirga E.
    Objective: It was aimed to investigate effects of Massive vaccinetion has been performing since 1998 in our country, to HBC seroprevalences according to socio-economic levels of children that de living in Manisa. Material and Methods: The study is a descriptive, cross-sectional field research. The study population was students, who were at the 3rd, 4th, 5th, and 6th grades of public primary schools in Manisa City Centren. Schools were classified in to three subcategories as low, intermediate and high level depending on the socio-economic level of the regions. Results: The number of the participating children in the study was 1504; 50.3%(n= 756) of this number comprised of boys and 49.7%(n= 748) of it comprised of girls. When the distribution according to socio-economic level is evaluated, the numbers of the children from high, intermediate and low level of socio-economic level were 16.2%(n= 243), 43.8%(n= 660) and 40.0%(n= 601), respectively. The carrier state rate according to year of birth from 1996 to 1999 are 1.7%, 1.5%, 1.1%and 0.8%respectively; where as the ratios of antibody titration at preventive level (>10 IU/mL) were 29.6%, 40.1%, 71.5% and 65.8%, res pectively (F= 84.40, p= 0.000). Depending on the results of last model with degraded logistic regression, to be born in pre-mass vaccination period was 4.01 times (95%GA: 3.19-5.05) riskier comparing to be born in mass vaccination period, whereas being in low socio-economic level was 4.25 times (95%GA: 3.36-5.36) riskier comparing to being in high-intermediate socioeconomic level in terms of sensitivity to he patitis B. Conclusion: As a conclusion, mass HBV vaccination, which has been employed for 10 years in our country, has caused a significant decrease in HBsAg positivity, especially in the childhood. Therefore, it should be maintained likewise with high vaccination rates. In addition, HBsAg screening of all pregnant women and sufficient immunization (vaccine and HBIG) of the new borns from baby carriers should not be disregarded at the birth. Copyright © 2010 by Türkiye Klinikleri.
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    Should a booster dose be administered in children after mass immunization for hepatitis B?
    (Brieflands, 2011) Tosun S.; Deveci S.; Kaplan Y.; Kasirga E.
    Background: Hepatitis B virus infection is a global health problem and vaccine-preventable disease, but the duration of the effects of HBV vaccination in infants is unknown. Objectives: The aim of this trial, which comprised children who had received 3 doses as part of the universal HBV immunization program and no additional doses, was to investigate anti-HBs titers and HBsAg status after 9 years. Patients and Methods: We performed a descriptive, cross-sectional field research study. The study sample, based on sociodemographics and minimum seroprevalence, was analyzed based on 10.00% ± 1.50 (95% confidence interval) (1150 individuals); trial was realized in a total of 1279 children (623 females and 656 males). Anti-HBs titers were measured by micro-EIA (Dia Sorin-Italy); titers < 10 IU/mL were negative, 10-49 IU/mL were low-positive, and > 50 IU/mL were high-positive. For anti-HBs titers below protective levels, HBsAg was measured by micro-EIA. Results: In approximately half of the children (48.5% in those living in semiurban areas and 42.3% in urban areas), antibody titers were below protective levels. Conclusions: Mass HBV vaccination, which was implemented in Turkey in 1998, significantly decreases HBsAg positivity in childhood. Nevertheless, it might be necessary to administer a booster dose after 8-9 years in children, especially those in low socioeconomic areas or in whom irregular/insufficient immunization is suspected. © 2011 Kowsar M.P.Co. All rights reserved.
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    Investigation of tetanus antitoxin titer levels in people over forty years of age; [Kırk yaşın üzerindeki insanlarda tetanoz Antitoksin titre düzeylerinin araştırılması]
    (Turkiye Klinikleri, 2012) Tosun S.; Deveci S.; Yücetürk M.; Dönmez A.B.; Kaplan Y.
    Objective: Tetanus is a disease that can be prevented with vaccination, but protective antitoxin titers decrease to undetectable levels with old age. The aim of this study is to evaluate tetanus antitoxin levels in individuals over 40 years of age and to investigate the vaccination and physical in-jury status via survey. Material and Methods: A total of 361 participants, 178 men and 183 women, were enrolled in the study and blood was drawn from each participant to measure tetanus antibody level by enzyme immunoassay (EIA) method. Results: Tetanus antibodies were undetectable in 55 male (30.9%) and 71 female patients (38.8%) at the end of the study. It was determined that tetanus antitoxin levels significantly decrease with age in both women and men especially after 50 years of age which is accepted as the limit age in which antibody is likely to be negative. Conclusion: In adult age group, booster vaccination for tetanus is recommended every 10 years in developing and developed countries, but this recommendation cannot be put into practice as anticipated. Similarly in our country, vaccination of adult age group is not common and tetanus vaccine is not generally administered at every ten years. The results of this study show that one dose of tetanus vaccine should be administered at least to individuals over 50 years of age, and individuals who do not recall their vaccination history should be taken into a three-dose vaccination program. © 2012 by Türkiye Klinikleri.
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    Pediatric inverted papilloma of the middle ear: Case report and review of the literature
    (Elsevier Ireland Ltd, 2014) Ulkumen B.; Kaplan Y.; Kiroglu A.F.; Bayram I.
    Inverted papilloma of middle ear is a very rare clinical entity. It has been reported only in the adult population. We report a middle ear inverted papilloma in an 11-year-old male. To the best of our knowledge it is the first pediatric inverted papilloma of middle ear. The patient had a history of chronic suppurative otitis media and the lesion was found during preoperative evaluation for a tympanoplasty procedure. Total excision of the lesion and a tympanoplasty operation was accomplished. We reviewed the middle ear inverted papilloma cases regarding the age distribution, pathophysiology, treatment and prognosis. © 2014 Elsevier Ireland Ltd.