Browsing by Author "Karakose A."

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    Analysis of radiofrequency ablation of small renal tumors in patients at high anesthetic and surgical risk: Urologist experience with follow-up results in the initial six months
    (Asian Pacific Organization for Cancer Prevention, 2013) Yuksel M.B.; Karakose A.; Gumus B.; Tarhan S.; Atesci Y.Z.; Akan Z.
    Background: To evaluate the results of various types of radiofrequency ablation (RFA) treatment of renal tumors in patients with excessive anesthetic and surgical risk. Materials and Methods: Data for RFA performed in in high risk patients were retrospectively evaluated. Other RFA applications in patients with no anesthetic and/or surgical risk were excluded. RFA was by ultrasound or CT guided percutaneous (USG/CT-PRFA) and retroperitoneally or transperitoneally laparoscopic (R/T-LRFA) techniques under general or local anethesia. Follow-up data of enhanced CT or MRI after 1, 3 and 6 months were analysed for twelve RFA applications. Results: The RFA applications included 4 (40%) left-sided, 5 (50%) right-sided and 1 (10%) bilaterally RFA (simultaneously 1 right and 2 left). The localizations of tumors were 2 (16.6%) upper, 5 (41.6%) mid and 5 (41.6%) lower pole. The RFA applications included 9 (75%) USG-PRFA, 1 (8.3%) CT-PRFA, 1 (8.3%) T-LRFA and 1 (8.3%) R-LRFA. The mean age was 65.3±8.5 (52-76) years. The mean tumor size was 29.6±6.08 (15-40) mm. No complications related to the RFA were encountered in any of the cases. Failure (residual tumour) was determined in 8.3% (1/12) of USG-RFA application. The success rate was thus 91.7% (11/12). Other 1st, 3rd and 6th months follow-up data revealed no residua and recurrence. Conclusions: RFA application appears to be safe as a less invasive and effective treatment modality in selected cases of small renal tumors in individuals with excessive anesthetic and also surgical risk.
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    The comparison of short term results of transobturatour tape and single incision midurethral sling procedures
    (Aras Part Medical International Press, 2013) Yuksel M.B.; Kose O.; Karakose A.; Gorgel S.N.; Yılmaz Y.; Gumus B.
    Objectives: We aimed to evaluate the efficacy of transobturatortape (TOT) and single incision mini sling (SIMS) procedures in the treatment of stress urinary incontinence (SUI).; Materials and Methods: The data of 32 patients who underwent TOT(Promedon®) or SIMS (Ophira®) operations related to SUI between January 2010 - August 2012 were retrospectively evaluated. The sample divided in two groups according to the operation type. The demographical features, preoperative, perioperative, and postoperative data were analysed and compared between two groups to evaluate the efficacy of the operations in SUI. All patients were assessed with a detailed history, physcical examination, cough test, Q-tip test, ultrasonography, postvoiding residual measurement, cystometry and UDI-6, IIQ-7 questionares. Postoperatively, the patients without any incontinence on cough test or sistometry were defined as the success.; Results: The parameters of age, menapousal status, number of vaginal delivery, and body mass index were similar in two groups. The mean operation time was significantly shorter in SIMS group (16±3 vs 27±5, p<0.05). Postoperative succes was not different between two groups (88% , %80 respectively, p>0.05). Postoperative UDI-6 and IIQ-7 scores were 3.5 ± 3.4 vs 3.8 ± 4.8 and 4.4 ± 4.2 vs 5.1 ± 5,6 respectively, and they were similar (p>0.05 in both). In addition, the improvement in these scores were not statistically significant between two groups (p> 0.05 in both).; Conclusion: SIMS procedure is safe and as effective as TOT with shorter operation time in the surgical teratment of female SUI. © 2014 / PMCARAS. All rights reserved.
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    Can cancer detection rate increase when transrectal biopsies were taken from the laterally?
    (Yuzuncu Yil Universitesi Tip Fakultesi, 2014) Karakose A.; Yuksel M.B.; Pirincci N.; Gorgel S.N.; Atesci Y.Z.; Gumus B.
    Acording to general opinion when biopsy is taken from the prostate’s lateral peripheral zone. More cancer is seen. In our study, the incidence of cancer in the lateral peripheral zone biopsies was investigated. In our study, 93 patients were analyzed retrospectively transrectal prostate biopsy. 12 core biopsies were taken from each patient. Medial peripheral zone (MPZ) and lateral peripheral zone (LPZ) biopsies compared the detection of prostate cancer. The average age of the patients was 67.2±10.3. Total PSA value in patients was found as 13.7 ng/mL. Prostate cancer was detected at the rate of 22.5% (21 patients) in 93 patients. 3 patients (14.3%) had prostate cancer in MPZ and 8 patients (38%) had prostate cancer in LPZ. Prostate cancer was detected at MPZ and LPZ at the rate of 47.7% (10 patients) in patients. Prostate cancer was more commonly detected in LPZ (p<0.05). Prostate biopsies of the LPZ biopsies more commonly cancer is seen. We believe it will increase the capture rate for prostate cancer if a sufficient number of biopsies were taken from the LPZ. © 2014, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
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    The effect of antibiotherapy on high serum PSA levels
    (Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Karakose A.; Yuksel M.B.; Pirincci N.; Gorgel S.N.; Atesci Y.Z.; Gumus B.
    This study investigated the effect of antibiotics in patients with PSA value high than 4 ng/mL on tPSA, fPSA and fPSA/tPSA ratio without missing cancer and avoiding unnecessary biopsies. A total of 96 patients were included into the study with detected high level than 4 ng/mL serum PSA. Patients were divided into 2 groups according to the high level of PSA value. Group 1 included 49 patients with PSA level between 4-10 ng/mL. Group 2 included 47 patients with PSA level higher than 10 ng/mL. Patients were treated with Ciprofloxacin (500mg b.i.d.) orally for 2 weeks. All patients' PSA levels were evaluated and analyzed before and after antibiotic treatment. Statistical analyses were performed with SPSS version 18. A p value <0.05 was considered as significant. The mean age was 61.6 ±5.7 (51-75) years in group 1 and 63.1 ±8.7 (55-74) years in group 2. Suspicious DRE findings were significantly high in group 2. The mean tPSA values were 6.82±0.42 and 5.93±0.36 before and after antibiotic treatment in group 1 respectively. There was no significant differences in tPSA value before and after antibiotic treatment in group 1. The mean tPSA values were 32.53±8.23 and 11.72±5.61 before and after antibiotic treatment in group 2 respectively. The mean tPSA value decreased significantly after antibiotic treatment in group 2. Prostate cancer was detected in 32 patients after TRUS guided prostate biopsy. Prostate cancer was identified in 13 patients in group 1 and 19 patients in group 2. Antibiotic treatment in patients with PSA levels higher than 10 ng/mL is effective on prostate biopsy decision and antibiotic treatment can prevent unnecessary prostate biopsies. © 2015 Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.