Browsing by Author "Kaya E."
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Item Evaluation of silicosis in ceramic workers; [Seramik fabrikasi işçilerinde silikozis.](2005) Sakar A.; Kaya E.; Celik P.; Gencer N.; Temel O.; Yaman N.; Sepit L.; Yildirim C.A.; Dagyildizi L.; Coşkun E.; Dinç G.; Yorgancioglu A.; Cimrin A.H.This study is aimed to evaluate the incidence of silicosis and the relation of it with personal and work-related factors among workers exposed to silica in ceramic factory. Workers were evaluated by respiratory symptoms, physical examination, pulmonary function and radiological findings. Occupational and Enviromental Pulmonary Disease Evaluation Questionnaire of the Turkish Thoracic Society Enviromental and Occupational Pulmonary Diseases Working Group was used. 365 of 626 workers had exposure to silica and the rest 261 were concerned as control group. There was no difference between mean age, duration of work and smoking pack year among the groups (p> 0.05). Cough and sputum rates were higher in silicosis group FEV1 and FVC values were lower in silica group but this was not statistically significant. When the two subgroups of silica group (the workers in high dust concentration and the ones in low concentration) were compared, the high concentrated group had significantly more sputum but the other symptoms and pulmonary functional parameters were not different significantly. 24 workers had parenchymal densities adjusted with pneumoconiosis. The workers with the pneumoconistic finding, had a higher mean age and longer duration of work. As a conclusion, ceramic industry has risk for silicosis. And the risk increase by time and age.Item Unusual foreign body aspiration; [Nadir görülen bir yabanci cisim aspirasyonu](2006) Çelik P.; Kaya E.; Şakar A.; Yorgancioǧlu A.Tracheobronchial foreign body aspiration in adults is rare when compared to children. In this case report, 76 years old female patient who aspirated a screw of tracheostomy canula which was taken out by fiberoptic bronchoscopy (FOB) was presented. This case showed us that education of patients about stoma care is important. The FOB can be used safely to get foreign body from distal airways.Item The prevalence of asthma and allergic symptoms in Manisa, Turkey (a western city from a country bridging Asia and Europe)(2006) Sakar A.; Yorgancioglu A.; Dinc G.; Yuksel H.; Celik P.; Dagyildizi L.; Coskun E.; Kaya E.; Ozyurt B.; Ozcan C.The aim of this study was to determine the prevalence of asthma and allergic symptoms in Manisa city center, Turkey, to evaluate the determinants effective on those values, and to review the prevalence rates reported from different parts of the country. Data were collected from 610 households and complete interviews were conducted with 1,336 adults over 18 years of age by using European Community Respiratory Health Survey-ECRHS questionnaire. The prevalences of current asthma, cumulative asthma and asthma-like symptoms were found in 1.2, 1.0 and 25.0%, respectively, of the 20-44 years age group and the prevalences of allergic rhinitis, allergic dermatitis and family atopy were found in 14.5, 10.9, and 15.2%, respectively, in all age group. Wheezing with breathlessness, wheezing without cold, woken up with shortness of breath and woken up with cold were reported by 9.1%, 6.9%, 6% and 16.1% of the study population, respectively. Gender, age, active or passive smoking, family atopy and home condition effect on prevalence of asthma and allergic symptoms. In this study prevalence of asthma correlated with the studies reporting low prevalence rates of Turkey.Item Prevalence of pseudoneurologic conversion disorder in an urban community in Manisa, Turkey(2007) Deveci A.; Taskin O.; Dinc G.; Yilmaz H.; Demet M.M.; Erbay-Dundar P.; Kaya E.; Ozmen E.Background: There is not a wide agreement upon rate of conversion disorder within Turkish population. The aim of this study was to determine the prevalence of conversion disorder with pseudoneurological symptoms or deficits and related risk factors in a city. Method: In total, 1,086 people, aged 15-65 years old, were selected from the city of Manisa, Turkey to take part in the study. We applied sociodemographic and health information questionnaires and the Composite International Diagnostic Interview (CIDI) Somatization Subscales to the samples. Results: The likelihood that an individual might have conversion disorder with pseudoneurological symptoms or deficits was found to be 5.6% (n = 61). The prevalence of conversion disorder with pseudoneurological symptoms or deficits was significantly higher among women (p < 0.0001), 15-24 year old women (p = 0.011) and 25-34 year old women (p = 0.003), people who live as squatters (p = 0.03), those with a history of psychiatric disorder (p < 0.0001) and those having a mother with a psychiatric disorder (p = 0.04). Conclusion: This study has shown the conversion disorder with pseudoneurological symptoms or deficits is inadequately frequent in the population. © Springer-Verlag 2007.Item Residual symptoms in bipolar disorder: The effect of the last episode after remission(2007) Kaya E.; Aydemir Ö.; Selcuki D.In this study it is aimed to assess interepisode residual symptoms in remitted bipolar disorder patients with a hypothesis that the last episode recovered has implications on residual symptomatology. The study was carried out with 23 bipolar patients diagnosed as mania (BP-M) and 20 bipolar patients diagnosed as depression (BP-D) in their last episode, and with 22 healthy controls in a university hospital clinic. All patients were in remission for at least 6 months. In the assessment Hamilton Depression Rating Scale (HAM-D), Young Mania Rating Scale (YMRS), Stroop Test, Auditory Verbal Learning Test (AVLT), increased latency positive-evoked potentials (P300), Global Assessment of Functioning Scale (GAF), and Social Functioning Scale (SFS) were used cross-sectionally. In affective symptomatology, the BP-M group had higher YMRS scores, and the BP-D group had higher HAM-D scores compared to the controls. P300 test results revealed low amplitude in the BP-D group. In the AVLT, verbal learning and delayed recall were significantly lower in the two bipolar groups. The Stroop tasks were not different in the groups. Concerning the SFS, social withdrawal was impaired in the two bipolar groups, whereas dependency-competency was impaired in the BP-M and employment/occupation was impaired in the BP-D group. As a conclusion, bipolar patients recovering from depressive episode may experience more impairment in daily functioning due to residual depressive symptoms and impairment of attention and memory. © 2007 Elsevier Inc. All rights reserved.Item What does the subjective assessment of cognitive functioning measure in bipolar disorder? Correlation with the objective assessment of cognitive functioning(Turkish Association of Nervous and Mental Health, 2009) Aydemir Ö.; Kaya E.Objective: Even in remission, cognitive deficits are frequently observed in bipolar disorder. Because these deficits are assessed with complex and comprehensive tests, they seem to be neglected in routine daily practice; however, assessing them with short self-rated questionnaires could be beneficial. This study aimed to investigate the correlation between objective and subjective cognitive assessment in bipolar disorder. Method: The study included 38 patients with bipolar disorder that were in remission for at least 6 months and 19 healthy controls. The Stroop Test and Auditory Verbal Learning Test were used for the objective assessment of cognitive functioning, and the cognitive functioning subscale of the Bipolar Disorder Functioning Questionnaire was used for the subjective assessment of cognitive functioning. Mood symptoms were assessed using the Hamilton Depression Rating Scale and Young Mania Rating Scale. Results: Based on objective assessment there were significant differences in all domains of the Auditory Verbal Learning Test between the bipolar patients and healthy controls, whereas there weren't any significant difference in Stroop Test results. Based on subjective assessment there were significant differences between the bipolar patients and healthy controls in terms of cognitive functioning subscale total score and first item score, but not in terms of the other items. When the correlation between the objective and subjective cognitive assessments was investigated, total score of the cognitive functioning subscale and 2 items-1. to run simple calculations in one's mind and 2. gathering and performing what one is asked to do-were moderately to weakly correlated with immediate recall, verbal learning, recognition, retrieval, and reading shape color. No correlation was observed between the other items of the cognitive functioning subscale. Conclusion: Based on subjective assessment of cognitive functioning, the bipolar patients tended to over-estimate themselves. Furthermore, bipolar patients tended to report more deficits correlated with objective cognitive assessment when they had to display active performance, whereas they did not report cognitive deficits at this level when such a condition was not present.Item The effects of residual affective symptoms on cognitive and social functioning in remitted bipolar patients; [Remisyondaki iki uçlu hastalarda kalinti duygudurum belirtilerinin bilişsel ve toplumsal işlevsellik üzerine etkisi](2009) Kaya E.; Aydemir O.; Selçuki D.Objective: In bipolar disorder, both cognitive and social functioning is impaired during remission. It is not well documented whether residual affective symptoms cause impairment in cognitive and social functions or cognitive impairment per se is the source of psychosocial dysfunction during remission. In this work, the effects of subsyndromal residual affective symptoms on cognitive and social functioning in remitted bipolar patients are studied. Materials and Methods: The study was carried out with 43 patients diagnosed as bipolar I disorder with a remission for at least 6 months. The mean age of the patients was 38.1±13.5 and 55.8% (n=24) were male. The mean duration of illness was 12.1±10.2 years and the mean number of previous episodes was 6.6±6.0. As healthy controls, 22 volunteers without any lifetime psychiatric and medical diagnosis or treatment were invited to the study. In the assessment Hamilton Depression Rating Scale (HAM-D), Young Mania Rating Scale (YMRS), Stroop Test, Auditory Verbal Learning Test (AVLT), increased latency positive-evoked potentials (P300), Global Assessment of Functioning Scale (GAF), and Social Functioning Scale (SFS) were used. In statistical analyses, linear regression analysis was performed. Results: HAM-D scores significantly affected cognitive functions such as P300 amplitude, immediate recall, verbal learning, delayed recall, recognition, retrieval, Stroop effect, and social functions such as social engagement, interpersonal behavior, prosocial activities, recreation, independence-performance and competency and employment. YMRS scores affected only verbal learning. Cognitive functions do not have any effect on mood symptoms or social functions. Discussion and Conclusion: Subsyndromal residual depressive symptoms seem to affect functioning in remitted bipolar patients. In order to improve the functioning of the bipolar patients, it will be helpful to implement strategies for these depressive symptoms.Item Primary central nervous system lymphoma in daily practice and the role of autologous stem cell transplantation in relapsed disease: A retrospective multicenter study(Elsevier Ltd, 2016) Erkurt M.A.; Berber I.; Tekgündüz E.; Dogu M.H.; Korkmaz S.; Demir C.; Yilmaz M.; Akay O.M.; Pala C.; Bilen Y.; Kaya E.; Sari I.; Sencan M.; Kuku I.; Altuntaş F.; Dal M.S.; Aydogdu I.We investigated the course of 54 patients presenting with primary central nervous system lymphoma, who were treated in daily practice. The patients were treated with chemotherapy and/or radiotherapy and/or intrathecal chemotherapy. At a median follow-up period of 23 months (range 1-71), median relapse-free survival (RFS) and overall survival (OS) were not reached. Estimated 2-year RFS and OS rates were 42% and 48%, respectively. Ten relapsed PCNSL patients underwent ASCT. Complete remission rate of these patients was 40%, with 20% treatment-related mortality. Estimated 2-year RFS and OS rates were 37% and 40%, respectively. The prognosis of patients with PCNSL, who received off-study treatment, is still dismal. © 2016 Elsevier Ltd.Item A multicenter experience of thrombotic microangiopathies in Turkey: The Turkish Hematology Research and Education Group (ThREG)-TMA01 study(Elsevier Ltd, 2018) Tekgündüz E.; Yılmaz M.; Erkurt M.A.; Kiki I.; Kaya A.H.; Kaynar L.; Alacacioglu I.; Cetin G.; Ozarslan I.; Kuku I.; Sincan G.; Salim O.; Namdaroglu S.; Karakus A.; Karakus V.; Altuntas F.; Sari I.; Ozet G.; Aydogdu I.; Okan V.; Kaya E.; Yildirim R.; Yildizhan E.; Ozgur G.; Ozcebe O.I.; Payzin B.; Akpinar S.; Demirkan F.Thrombotic microangiopathies (TMAs) are rare, but life-threatening disorders characterized by microangiopathic hemolytic anemia and thrombocytopenia (MAHAT) associated with multiorgan dysfunction as a result of microvascular thrombosis and tissue ischemia. The differentiation of the etiology is of utmost importance as the pathophysiological basis will dictate the choice of appropriate treatment. We retrospectively evaluated 154 (99 females and 55 males) patients who received therapeutic plasma exchange (TPE) due to a presumptive diagnosis of TMA, who had serum ADAMTS13 activity/anti-ADAMTS13 antibody analysis at the time of hospital admission. The median age of the study cohort was 36 (14-84). 67 (43.5%), 32 (20.8%), 27 (17.5%) and 28 (18.2%) patients were diagnosed as thrombotic thrombocytopenic purpura (TTP), infection/complement-associated hemolytic uremic syndrome (IA/CA-HUS), secondary TMA and TMA-not otherwise specified (TMA-NOS), respectively. Patients received a median of 18 (175) plasma volume exchanges for 14 (153) days. 81 (52.6%) patients received concomitant steroid therapy with TPE. Treatment responses could be evaluated in 137 patients. 90 patients (65.7%) achieved clinical remission following TPE, while 47 (34.3%) patients had non-responsive disease. 25 (18.2%) non-responsive patients died during follow-up. Our study present real-life data on the distribution and follow-up of patients with TMAs who were referred to therapeutic apheresis centers for the application of TPE. © 2018 Elsevier LtdItem Correlation of Alexithymia with Grief and Depression Symptom Severity in Persistent Complex Bereavement Disorder(Springer, 2021) Kaya E.; Aydemir Ö.This study aimed to compare the depression and grief levels between patients with persistent complex bereavement disorder who have alexithymia and those who do not have alexithymia. This study also aimed to examine the correlations between these variables. A total of 80 patients with persistent complex bereavement disorders were included and divided into two groups: alexithymia (n = 45) and nonalexithymia (n = 35). Each patient was evaluated using the Toronto Alexithymia Scale, the Inventory of Complicated Grief and the Beck Depression Inventory. Individuals with alexithymia who have symptoms of complicated grief may experience more severe depression and grief than patients without alexithymia. Among individuals with alexithymia, the difficulty identifying feelings dimension may be a predictor of complicated grief, and the externally oriented thinking dimension appears to be significant in terms of masking depressive symptoms. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.Item Efficacy and safety of ruxolitinib in patients with myelofibrosis: A retrospective and multicenter experience in turkey(Turkiye Klinikleri, 2021) Soyer N.; Ali R.; Turgut M.; Haznedaroğlu İ.C.; Yilmaz F.; Aydoğdu İ.; Pir A.; Karakuş V.; Özgür G.; Kiş C.; Ceran F.; Ilhan G.; Özkan M.; Aslaner M.; Ince İ.; Yavaşoğlu İ.; Gediz F.; Sönmez M.; Güvenç B.; Özet G.; Kaya E.; Vural F.; Şahin F.; Töbü M.; Durusoy R.; Saydam G.Background/aim: The aim of this study is to assess the efficacy and safety of ruxolitinib in patients with myelofibrosis. Materials and methods: From 15 centers, 176 patients (53.4% male, 46.6% female) were retrospectively evaluated. Results: The median age at ruxolitinib initiation was 62 (28–87) and 100 (56.8%) of all were diagnosed as PMF. Constitutional symptoms were observed in 84.7%. The median initiation dose of ruxolitinib was 30 mg (10–40). Dose change was made in 69 (39.2%) patients. Forty seven (35.6%) and 20 (15.2%) of 132 patients had hematological and nonhematological adverse events, respectively. The mean spleen sizes before and after ruxolitinib treatment were 219.67 ± 46.79 mm versus 199.49 ± 40.95 mm, respectively (p < 0.001). There was no correlation between baseline features and subsequent spleen response. Overall survival at 1-year was 89.5% and the median follow up was 10 (1–55) months. We could not show any relationship between survival and reduction in spleen size (p = 0.73). Conclusion: We found ruxolitinib to be safe, well tolerated, and effective in real-life clinical practice in Turkey. Ruxolitinib dose titration can provide better responses in terms of not only clinical benefit but also for long term of ruxolitinib treatment. © TÜBİTAK.Item Efficacy and Safety of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia: Retrospective Analysis of Real-Life Data; [Kronik Lenfositik Lösemili Hastalarda İbrutinib Tedavisinin Etkililiği ve Güvenilirliği: Gerçek Hayat Verilerinin Retrospektif Analizi](Turkish Society of Hematology, 2021) Tombak A.; Tanrıkulu F.P.; Durusoy S.S.; Dinçyürek H.D.; Kaya E.; Ümit E.G.; Yavaşoğlu İ.; Mehtap Ö.; Deveci B.; Özcan M.A.; Terzi H.; Okay M.; Sayınalp N.; Yılmaz M.; Okan V.; Kızıklı A.; Özcan Ö.; Çetin G.; Demircioğlu S.; Aydoğdu İ.; Saydam G.; Davulcu E.A.; İlhan G.; Uçar M.A.; Özet G.; Akpınar S.; Turgut B.; Berber İ.; Kurtoğlu E.; Sönmez M.; Batur D.S.; Yıldırım R.; Özkocamaz V.; Güneş A.K.; Sahip B.; Ertop Ş.; Akay O.M.; Baştürk A.; Doğu M.H.; Akdeniz A.; Ünal A.; Seyhanlı A.; Gürkan E.; Çekdemir D.; Ferhanoğlu B.Objective: This study aimed to retrospectively evaluate the efficacy, safety, and survival outcome of single-agent ibrutinib therapy in chronic lymphocytic leukemia patients. Materials and Methods: A total of 136 patients (mean age ± standard deviation: 64.6±10.3 years, 66.9% males) who had received at least one dose of ibrutinib were included in this retrospective multicenter, noninterventional hospital-registry study conducted at 33 centers across Turkey. Data on patient demographics, baseline characteristics, laboratory findings, and leukemia-cell cytogenetics were retrieved. Treatment response, survival outcome including overall survival (OS) and progression-free survival (PFS), and safety data were analyzed. Results: Overall, 36.7% of patients were categorized as Eastern Cooperative Oncology Group (ECOG) class 2-3, while 44.9% were in Rai stage 4. Fluorescence in situ hybridization revealed the presence of del(17p) in 39.8% of the patients. Patients received a median of 2.0 (range: 0-7) lines of pre-ibrutinib therapy. Median duration of therapy was 8.8 months (range: 0.4-58.0 months). The 1-year PFS and OS rates were 82.2% and 84.6%, respectively, while median PFS time was 30.0 (standard error, 95% confidence interval: 5.1, 20.0-40.0) months and median OS time was 37.9 (3.2, 31.5-44.2) months. Treatment response (complete or partial response), PFS time, and OS time were better with 0-2 lines versus 3-7 lines of prior therapy (p<0.001, p=0.001, and p<0.001, respectively), with ECOG class 0-1 versus class 2-3 (p=0.006, p=0.011, and p=0.001, respectively), and with Rai stage 0-2 versus 3-4 (p=0.002, p=0.001, and p=0.002, respectively). No significant difference was noted in treatment response rates or survival outcome with respect to the presence of comorbidity, bulky disease, or del(17p). While 176 adverse events (AEs) were reported in 74 (54.4%) patients, 46 of those 176 AEs were grade 3-4, including pneumonia (n=12), neutropenia (n=11), anemia (n=5), thrombocytopenia (n=5), and fever (n=5). Conclusion: This real-life analysis confirms the favorable efficacy and safety profile of long-term ibrutinib treatment while emphasizing the potential adverse impacts of poorer ECOG performance status, heavy treatment prior to ibrutinib, and advanced Rai stage on patient compliance, treatment response, and survival outcomes. © 2021 by Turkish Society of Hematology Turkish Journal of Hematology, Published by Galenos Publishing House.Item Parental Acceptance/Rejection Perceptions and Attachment Styles of Men With Online Gambling Disorder(Springer, 2022) Kaya E.; Deveci A.Online gambling disorder has recently emerged as a significant public health issue. Family dynamics play an important role in the development of online gambling disorder. In this research, the aimed to compare the parental acceptance/rejection and attachment styles of individuals with online gambling disorder with a healthy control group. Also, the relationship between parental acceptance/rejection and attachment styles was examined in individuals with online gambling disorder. The study group consisted of 53 male patients with online gambling disorder and 57 healthy controls. The individuals with online gambling disorder perceived more rejection from mothers but especially from fathers than the individuals in the control group. Paternal hostility/aggression and indifference/neglect are determinants of online gambling behavior. The individuals with online gambling disorder had lower levels of secure attachment and higher levels of dismissive and fearful attachment than the individuals in the control group. Both secure attachment style and dismissive attachment style are thought to be determinants of gambling behavior. Mother-father rejection and insecure attachment are important in terms of creating risk for online gambling. Assessment of the effects of maternal and especially paternal rejection in online gambling disorder will be beneficial within the scope of preventive mental health. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Item Demographic and clinical characteristics of inpatient stroke patients in Turkey(Turkish Society of Physical Medicine and Rehabilitation, 2022) Külcü D.G.; Kuran B.; Karahan A.Y.; Özgirgin N.; Başaran S.; Yalıman A.; Savaş S.; Tıkız C.; Aktaş İ.; Bardak A.; Tuncer T.; Yılmaz F.; Erhan B.; Şirzai H.; Çelik B.; Durlanık G.; Doğu B.; Öncü J.; Hüner B.; Öztürk G.; Eskiyurt N.; Akpınar F.M.; Özkan F.Ü.; Paker N.; Buğdaycı D.S.; Gündüz B.; Şatır Ö.; Atalay N.Ş.; Yıldız N.; Altındağ Ö.; Demir S.E.; Kaya E.; Uçar D.; Sarı A.; Karataş G.K.; Taşkıran Ö.Ö.Objectives: This study aims to assess the stroke rehabilitation facilities provided by university hospitals (UHs) and training and research hospitals (TRHs) and to evaluate the geographical disparities in stroke rehabilitation. Patients and methods: Between April 2013 and April 2014 a total of 1,529 stroke patients (817 males, 712 females; mean age: 61.7±14.0 years; range, 12 to 91 years) who were admitted to the physical medicine and rehabilitation clinics in 20 tertiary care centers were retrospectively analyzed. Demographic, regional and clinical characteristics, details of rehabilitation period, functional status, and complications were collected. Results: The median duration of stroke was five (range, 1 to 360) months. The ratio of the patients treated in the TRH in the Marmara region was 77%, but only 25% of the patients were living in the Marmara region. Duration of hospitalization was longer in the TRHs with a median of 28 days compared to those of UHs (median: 22 days) (p<0.0001). More than half of the patients (55%) were rehabilitated in the Marmara region. Time after stroke was the highest in the Southeast region with a median of 12 (range, 1 to 230) months and the lowest in the Aegean region with a median of four (range, 1 to 84) months. Conclusion: This study provides an insight into the situation of stroke rehabilitation settings and characteristics of stroke patients in Turkey. A standard method of patient evaluation and a registry system may provide data about the efficacy of stroke rehabilitation and may help to focus on the problems that hinder a better outcome. © 2022 All right reserved by the Turkish Society of Physical Medicine and Rehabilitation.Item Genetic diversity of Lilium candidum natural populations in Türkiye evaluated with ISSR and M13-tailed SSR markers(Springer, 2024) Tokgöz H.B.; Çetin Ö.; Kaya H.B.; Akkale C.; Yildirim H.; Pirhan A.F.; Kaya E.; Altan F.The Liliaceae family includes the perennial, herbaceous, monocotyledonous plant Lilium candidum (L. candidum). The cosmetics, fragrance, and pharmaceutical industries regularly use L. candidum. It has been widely used in traditional medicine for wound healing, and its anti-inflammatory, antidiabetic, antimicrobial, and anticancer effects have been demonstrated in various studies. Natural populations of L. candidum are significantly affected by biotic and abiotic factors such as anthropological pressure, diseases, pathogen attacks, fossil fuel pollution, and climate change. Overcollection and destruction of its habitat put L. candidum into the endangered category. Therefore, it is of great importance to preserve this plant's genetic diversity, which plays a crucial role in adapting to different conditions, preserving evolutionary potential, and breeding studies. Molecular markers are essential in breeding and evolution studies to conserve genetic resources. Because of its economic and medical importance, various DNA markers have been used to evaluate the genetic diversity of L. candidum accessions. In this study, the genetic diversity of L. candidum, which is native to Türkiye, was determined with ISSR and SSR molecular markers among accessions collected from seven different cities and 76 accessions (Muğla, İzmir, Aydın, Antalya, Balıkesir, Denizli, and Manisa). Genetic distances and phylogenetic analysis were carried out using the software TASSEL 5.2.63. The assessment of genetic diversity was visualized through a UPGMA dendrogram. The resulting phylogenetic tree revealed two distinct groups. The closest and farthest accessions were determined according to the genetic distance matrix. It was determined that the highest genetic distance value was between 19 (Balıkesir, Kepsut) and 76 (Muğla, Ula) accessions (0.5390946) and the lowest genetic distance value was between 53 (Muğla, Marmaris) and 54 (Muğla, Marmaris) accessions (0.1069968). © 2024, The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.