Browsing by Author "Kayikçioǧlu Ö."

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    The influence of religious fasting on basal tear secretion and tear break-up time
    (1998) Kayikçioǧlu Ö.; Erkin E.F.; Erakgün T.
    Muslims abstain from food and drink from dawn to sunset during the holy month of Ramadan. An extended strict fasting may influence tear secretion and quality. We investigated changes in basal tear secretion (BTS) and tear break-up time (BUT) at the beginning and at the end of fasting on 32 healthy male patients with a mean age of 22.3 ± 2.9 years. Body weight and urine specific gravity were also determined to assess the extent of dehydration due to fasting. Each case lost 0.1-1.25 kg of body weight while urine specific gravity changes were statistically insignificant. Mean BTS amount was 19.9 ± 10.9 mm at the initial examination and 19.7 ± 11.5 mm at the end of fasting (p = 0.9). BUT values were 20.1 ± 9.3 sec at the beginning of fasting and 23.5 ± 14.9 sec at the end of fasting (p = 0.19). We found that religious fasting in the winter season does not seem to affect BTS and BUT values in healthy individuals.
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    Electrocardiographic changes during subconjunctival injections
    (1999) Kayikçioǧlu Ö.; Kayikçioǧlu M.; Erakgün T.; Güler C.
    Electrocardiographic changes were investigated in 53 patients during subconjunctival drug injections. Decrease in heart-rate of more than 10% or arrhythmia was observed in 25 (47.2%) of the patients, who were considered to have a positive oculocardiac reflex. In the control group of 35 patients, only 3 (8.6%) were found to have a significant decrease in heart rate during blood sampling from antecubital vein (p = 0.000). Young age was a significant risk factor for oculocardiac reflex during injections (p = 0.01). Patient gender, verbal pain score, satiety, experience of periocular injections, injected drug type were not found to be risk factors. All patients with oculocardiac reflex were asymptomatic; however, it is still wise to have emergency supplies ready for any circulatory derangement during subconjunctival injections.
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    Ocular findings in a measles epidemic among young adults
    (Swets en Zeitlinger B.V., 2000) Kayikçioǧlu Ö.; Kir E.; Söyler M.; Güler C.; Irkeç M.
    Purpose: To present ocular findings in a measles epidemic outbreak among young adults. Methods: Ophthalmic lesions in an unselected group of 61 young military personnel with measles were followed. Eighteen of the patients had symmetric keratitis in both eyes. They were treated with diclofenac sodium eyedrops qid in the right eye, while the left eye was observed untreated. The disappearance of the corneal lesions in both eyes was compared. Results: Forty patients (65.6%) had measles conjunctivitis with bulbar and tarsal conjunctival hyperemia. Five (8.2%) had increased mucous secretion. Thirty-five (57.4%) had superficial punctate conceal epithelial and subepithelial lesions which stained with fluorescein. Ten patients had corneal lesions without evident conjunctival pathology. Fourteen patients had subconjunctival hemorrhages, it of whom had bilateral lesions mostly in the superonasal quadrant. The time to disappearance of corneal lesions was 4.5 ± 3.2 days in the diclophenac-treated right eyes, and 4.1 ± 3.8 days in the left eyes. We did not observe a significant difference in the healing time between the two eyes (P = 0.75) Conclusion: Measles did not cause major ocular complications in healthy patients. Keratitis was unresponsive to diclophenac sodium eyedrops with respect to healing time and end result.
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    Fluorescein dye disappearance test in patients with different degrees of epiphora
    (Wichtig Editore s.r.l., 2002) Toprak A.B.; Erkin E.F.; Kayikçioǧlu Ö.; Seymenoǧlu G.; Güler C.; Unlu H.H.
    PURPOSE. To assess the diagnostic efficacy of a modification of the fluorescein dye disappearance test (DDT) in patients with different degrees of epiphora. METHODS. DDT was performed by instilling a drop of 2% fluorescein in the eye. Schirmer tear test strips were placed in the lower conjunctival fornix, after 3 and 10 minutes. The colour dilution on the strips was compared to a scale with known standards and the most closely comparable colour dilution was chosen and recorded as the visual scale test (VST) grade of the strip. The grey-scale value (GV) of each strip was calculated by computer image analysis. The control group comprised 44 patients, mean age 44.8 years (SD 7.5, range 30-60). There were 13 patients in group 1 with moderate epiphora; mean age was 44.2 years (SD 9.5, range 30-60). There were 17 patients in group 2 with severe epiphora; mean age was 48.3 years (SD 7.7, range 37- 60). RESULTS. VST and GV differed significantly between controls and group 1 patients at 3 minutes (p=0.002, p=0.001), and between controls and group 2 patients at 3 minutes (p<0.001, p<0.001). There was no difference between groups 1 and 2 patients in VST and GV at 3 minutes. The differences were highly significant between controls and group 1 at 10 minutes (p=0.001, p=0.007), and between controls and group 2 at 10 minutes (p<0.001, p<0.001). The differences in GV and VST between groups 1 and 2 were significant at 10 minutes (p=0.026, p=0.018). CONCLUSIONS. This modified DDT permits identification of different degrees of epiphora in a non-invasive manner, it can therefore be used to evaluate the outcome of different treatment strategies.
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    Human cataractous lens nucleus implanted in a sheep eye lens as a model for phacoemulsification training
    (2004) Kayikçioǧlu Ö.; Eǧrilmez S.; Emre S.; Erakgün T.
    We describe a realistic and inexpensive experimental cataract model for phacoemulsification training. After a capsulorhexis is performed, a deep cavity in the lens of an enucleated sheep eye is formed by phacoemulsification through a lateral incision. An undamaged human cataractous lens nucleus obtained by extracapsular cataract extraction is inserted in the preformed cavity, resting in the center of a cortex cushion. Phacoemulsification training is performed through a corneal tunnel incision. The experimental model is prepared with a human cataractous lens nucleus of the preferred hardness, simulating nuclear phacoemulsification in humans. © 2004 ASCRS and ESCRS.
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    Effects of latanoprost and betaxolol on cardiovascular and respiratory status of newly diagnosed glaucoma patients
    (2006) Erkin E.F.; Çelik P.; Kayikçioǧlu Ö.; Deveci H.M.; Şakar A.
    Aims: To investigate the cardiovascular and respiratory effects of topical latanoprost 0.005% and topical betaxolol 0.25% monotherapy in newly diagnosed glaucoma patients. Methods: Forty newly diagnosed glaucoma patients were enrolled in this prospective, observer-masked, randomized, parallel study. Patients received either latanoprost 0.005% or betaxolol 0.25% for a duration of 3 months. Baseline evaluation included intraocular pressure (IOP) measurement and cardiorespiratory examinations including pulse rate, systolic and diastolic blood pressure measurements and spirometry. These measurements were repeated after 3 months. Results: Both latanoprost and betaxolol reduced IOP significantly (p = 0.001). After 3 months of therapy, the mean pulse rate, systolic and diastolic blood pressure values of the betaxolol group were reduced (p = 0.027, p = 0.07 and p = 0.016, respectively). No significant changes occurred in the cardiovascular measurements of the latanoprost group (p > 0.05). There were no significant changes in any of the spirometric measurements tested for both groups (p > 0.05). Conclusion: Both latanoprost and betaxolol are safe concerning respiratory functions. Betaxolol may cause small changes in the cardiovascular system, suggesting that blood pressure and pulse rates should be checked before and in regular intervals after prescribing it for the elderly. Latanoprost seems to be a safe medication in view of absence of systemic cardiovascular and respiratory side effects. Copyright © 2006 S. Karger AG.
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    The relationship between angiotensin converting enzyme insertion/deletion polymorphism and age-related macular degeneration
    (2011) Üçer B.; Kayikçioǧlu Ö.; Seymenoǧlu G.; Var A.; Çam S.
    Background: To assess the role of serum angiotensin converting enzyme (ACE) levels and ACE insertion /deletion (I/D) genetic polymorphism in Turkish age-related macular degeneration (AMD) patients and control subjects. Methods: This prospective study consisted of 78 patients with AMD and 68 control subjects. The I/D polymorphism of the ACE was carried out by polymerase chain reaction. Serum ACE levels were determined by using the ELISA method. Results: There was no significant difference in the mean serum values of ACE between the control and patient groups (p = 0.107). The genotypic frequencies of ACE polymorphism in the control and patient groups were not significantly different either (p = 0.218). Conclusion: We could not show a significant role of serum ACE levels and ACE I/D genetic polymorphism in the etiopathogenesis of AMD in the Turkish population, and our findings did not support the idea that serum ACE levels and ACE DD genotype were risk factors for AMD. © 2011 Informa Healthcare USA, Inc.
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    Vitreoretinal interface in asymptomatic fellow eyes of patients with unilateral macular holes; [Tek tarafli idiopatik maküla deliǧi olan olgularin asemptomatik diǧer gözlerinde vitreoretinal arayüzey özellikleri]
    (2013) Seymenoǧlu G.; Ulusoy O.; Başer E.; Kayikçioǧlu Ö.; Kurt E.; Ilker S.S.
    Purpose: To compare the vitreoretinal interface of the asymptomatic fellow eyes of patients with unilateral idiopathic macular holes (MH) with the asymptomatic fellow eyes of patients with idiopathic epiretinal membranes (ERM) and with the healthy eyes. Materials and Methods: Thirty-tree patients with unilateral MH (group 1), 33 patients with unilateral ERM (group 2) and 33 healthy eyes were included in the study. All patients underwent a comprehensive ophthalmologic examination and spectral domain optical cohorence tomography (OCT) was performed on all eyes. The incidence of the features of the vitreoretinal interface and foveal micro-structures in the OCT images were compared among the asymptomatic fellow eyes of patients with unilateral MH, ERM and one of the randomly selected healthy eyes of normal individuals which have any ophthalmic pathology except refractive errors. A complete posterior vitreus detachment (PVD) was considered to be present if the Weiss ring was seen on biomicroscopy or a hiper-reflective band representing a posterior hyaloid membrane over the entire macula was seen on OCT. Results: The incidence of perifoveal PVD was 45.5% in group 1, 21.2% in group 2 and 24.2% in group 3. The OCT scans showed different types of foveal deformations associated with vitreofoveal adhesions in eyes without a total PVD. The incidence of the foveal deformations associated with vitreofoveal adhesions was significantly higher (p<0.039) in the fellow eyes of the unilateral MH group (27%) than that in the other groups (0%). The OCT scans also showed residual foveal deformations in eyes with total PVD. The incidence of residual foveal deformation in eyes with total PVD was similar between MH and ERM groups (33%-27%, p=0,75), but it was significantly higher in the MH (33%) and ERM (27%) groups than that in healthy eyes (19%, p<0.01). Conclusion: The higher incidence of foveal deformations in the asymptomatic fellow eyes of patients with unilateral MH with vitreofoveal adhesions suggests that patients in whom MH may develop have abnormally strong vitreofoveal adhesions sufficient to cause foveal deformation and macular holes.