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  1. Home
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Browsing by Author "Keles, GT"

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    Relationship between nutrition and ASA-classification in the elderly
    Sakarya, M; Karadag, F; Lüleci, N; Keles, GT; Topçu, I; Erinçler, T
    Objective: Old age and bad nourishment are risk factors for the postoperative period. In this study, the mini nutritional assessment (MNA) of elderly patients was evaluated before the operation and compared with their ASA-classification. Methods: 215 outpatients (age > 60 years) were included. MNA-score was fixed as follows: MNA 24 - 30 = normal (MNA I); MNA 17-23.5 = risk of malnutrition (MNA II) MNA < 17 = undernourished (MNA III). In addition, the ASA-score of all patients was registered. chi(2)-, Mann-Whitney-U- and correlation analysis were used for statistical analysis. A cut off-value of 24 was fixed for MNA and correlated with the ASA-score. Results: 34,9% of all patients were allocated to MNA II or III, but only 19.9% to ASA III or IV. The sensivity of the ASA-classification for evaluation of the nutritional status was 0.33, selectivity was 0.87, positive predictive value was 0.58 and negative predictive value was 0.70. Conclusion: ASA evaluation is not suitable for assessment of the nutritional status. With regard to typical postoperative complications, the nutritional status of patients should be assessed separately.
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    Effects of High-Dose Rocuronium on the QTc Interval During Anaesthesia Induction in Patients Undergoing Coronary Artery Bypass Graft Surgery
    Agdanli, D; Öztürk, T; Ütük, O; Keles, GT
    Objective: Existing myocardial damage in coronary artery disease patients causes prolonged QT syndrome. The primary objective of this trial is to explore the effects of different doses of the muscle relaxant agent rocuronium (0.6 mg kg-1 and 1.2 mg kg-1) on QTc following anaesthetic induction. The second objective is to determine the incidence and kinds of arrhythmias. Methods: In this prospective and randomized trial, patients undergoing elective coronary artery revascularization surgery were included in one of two groups. Both groups took the same anaesthetic induction agents: midazolam and fentanyl. Rocuronium was administered in Group 1 (n=20) with dose of 0.6 mg kg-1 and in Group 2 (n=20) with a dose of 1.2 mg kg-1 for muscle relaxation. Heart rate, average arterial pressure and QTc were recorded before induction (T0), after induction (T1), after muscle relaxant (T2), and 2 minutes (T3) and 5 minutes after intubation (T4). Results: QTc was significantly longer 2 minutes after intubation (in Group 1 and Group 2, respectively, 447.9 +/- 28.3 and 466.1 +/- 37.8 ms) than at the beginning (respectively, 426.9 +/- 25.7, 432.0 +/- 35.5 ms) (p<0.01). In the intergroup comparison, average QTc values were similar in all trial periods (p>0.05). The prevalence of arrhythmias in between Group 1 (35%, n=7) and Group 2 (15%, n=3) was similar (p=0.06). Arrhythmias were recorded 2 minutes after intubation in both groups (n=10, 25%). Conclusion: In patients undergoing coronary artery revascularization surgery, rocuronium doses of 0.6 mg kg-1 and 1.2 mg kg-1 prolong the QTc interval after intubation. Cardiac arrhythmias related to long QTc arising after intubation should be taken into consideration.
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    Isolation and in vitro cultivation of human urine-derived cells: an alternative stem cell source
    Tayhan, SE; Keles, GT; Topçu, I; Mir, E; Gürhan, SID
    Objective: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue specimens obtained during open or endoscopic surgery. Within the context of the present study our aim was to isolate cells from human urine by an alternative and safe technique rather than using the indicated method. Material and methods: After human urine samples had been collected from young and healthy donors via urethral catheterization, cells were precipitated by centrifugation and cultured. Following this isolation procedure, cells were characterized by immunocytochemical method using specific antibodies. Results: When these cells were characterized by immunocytochemical methods using specific antibodies some of them were positive for mesenchymal stem cell marker CD90 while the others were labelled with urothelial marker cytokeratin 7. When all these results were taken into consideration, urothelial cells together with stem cells were observed in the urine-derived cell population. Conclusion: According to the results obtained from this study human urine may be preferred as an alternative stem cell and urothelial cell source in that this method is and easily reproducible non-invasive method.
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    Assessment of neuromuscular and haemodynamic effects of cisatracurium and vecuronium under sevoflurane-remifentanil anaesthesia in elderly patients
    Keles, GT; Yentür, A; Çavus, Z; Sakarya, M
    Background and objective: Neuromuscular block times, quality of muscle relaxation for tracheal tube insertion, and the haemodynamic effects after cisatracurium and vecuronium under sevoflurane-remifentanil anaesthesia were compared in elderly patients. Methods: The study was performed in 40 patients over 65 yr of age. Anaesthesia was induced with thiopental, and maintained with sevoflurane in N2O/O-2 and remifentanil. Cisatracurium 0.15 mg kg(-1) or vecuronium 0.1 mg kg(-1) were administered after induction. Intubation was attempted when neuromuscular block was 95%. Onset time, clinical duration of action, recovery index, spontaneous recovery time and tracheal intubation conditions were assessed. Haemodynamic parameters were also monitored. Results: The average ages of the patients were 72.5 +/- 5.1 and 73.6 +/- 6.3 in the cisatracurium and vecuronium groups, respectively. Onset time was significantly shorter after vecuronium, 158 +/- 34 s vs. 200 +/- 50 s, respectively. Recovery index was significantly shorter after cisatracurium, 19.5 +/- 7.5 s vs. 33.7 +/- 18.6 s (P < 0.05). Clinical duration and spontaneous recovery time were similar in both groups as well as haemodynamic variables. Conclusions: In elderly patients, vecuronium has a faster onset time while cisatracurium has a shorter recovery index under sevoflurane-remifentanil anaesthesia.
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    Methanol poisoning with necrosis corpus callosum
    Keles, GT; Örgüç, S; Toprak, B; Özaslan, S; Sakarya, M
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    The effect of regional and general anaesthesia on cerebral oxygenation in shoulder arthroscopy
    Acikel, A; Topcu, I; Ozturk, T; Keles, GT; Ozalp, T
    Aim: Shoulder arthroscopy in the beach-chair position can negatively affect cerebral perfusion and oxygenation, and thus, neurocognitive function. In this study, we aimed to compare the effects of general and regional anaesthesia (GA and RA, respectively) on cerebral oxygenation in patients undergoing shoulder arthroscopy in the beach-chair position. Material and Methods: This prospective, randomized study included 60 patients who underwent shoulder arthroscopy in the beach-chair position. Patients were divided into two groups: (1) GA (n = 30), and (2) RA using an interscalene brachial plexus block (ISB; n = 30). All patients were laid supine prior to GA or ISB (T0), and after induction of GA or ISB (T1). Next, patients were placed in the beach-chair position. The right and left cerebral oxygen saturation (NIRS-R, NIRS-L, respectively), peripheral oxygen saturation (SpO2), heart rate (HR), and mean arterial pressure (MAP) values were recorded at T0 and T1, as well as 5 (T2), 10 (T3), 20 (T4), and 30 minutes (T5) after patients were placed in the beach-chair position. Results: Patient's clinical characteristics, initial laboratory findings, and perioperative data were similar in both groups. Compared to T0, MAP was significantly lower at T1, T2, T3, and T4 in the GA group. Tukey's HSD test indicated p<0.05, p<0.0001, p<0.0001, and p<0.001, respectively. Although NIRS-R and NIRS-L values fluctuated substantially, there were no differences between groups at any of the pre-defined time points. Discussion: ISB in the beach-chair position may better preserve cerebral oxygenation compared to GA.
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    Evaluation of hemostatic changes using thromboelastography after crystalloid or colloid fluid administration during major orthopedic surgery
    Topçu, I; Çivi, M; Öztürk, T; Keles, GT; Çoban, S; Yentür, EA; Okçu, G
    The effects of Ringer lactate, 6% hydroxyethyl starch (130/0.4) or 4% succinylated gelatin solutions on perioperative coagulability were measured by thromboelastography (TEG). Seventy-five patients (ASA I-III) who were to undergo major orthopedic procedures performed under epidural anesthesia were included in the study. Patients were randomly divided into three groups of 25 each for the administration of maintenance fluids: group RL (Ringer lactate), group HES (6% hydroxyethyl starch 130/0.4), and group JEL (4% gelofusine solution). Blood samples were obtained during the perioperative period before epidural anesthesia (t1, baseline), at the end of the surgery (t2), and 24 h after the operation (t3). TEG data, reaction time (R), coagulation time (K), angle value (alpha), and maximum amplitude (MA) were recorded. TEG parameters changed from normal values in all patients. In group RL, R and K times decreased compared to perioperative values while the alpha angle and MA increased (P < 0.05). In group HES, R and K times increased, however, the alpha angle and MA decreased (P < 0.05). In group JEL, R time increased (P < 0.05), but K time, alpha angle and MA did not change significantly. In the present study, RL, 6% HES (130/0.4) and 4% JEL solutions caused changes in the coagulation system of all patients as measured by TEG, but these changes remained within normal limits.
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    Comparison of Patient Satisfaction Between General and Spinal Anaesthesia in Emergency Caesarean Deliveries
    Açikel, A; Öztürk, T; Göker, A; Hayran, GG; Keles, GT
    Objective: Obstetric anaesthesia aims to deliver a healthy baby as well as render a comfortable operation for the mother. This study compared general and spinal anaesthesia in terms of the quality of recovery and patient satisfaction in women undergoing emergency caesarean deliveries. Methods: In total, 100 patients were enrolled in this prospective, single-blind, cross-sectional clinical study. Patients were divided into spinal (n=50) and general (n=50) anaesthesia groups. The recovery score, pain and satisfaction were evaluated by Quality of Recovery Score (QoR-40), Visual Analogue Scale (VAS) and Numeric Rating Scale (NRS) at 24 hours postoperatively. Results: The total QoR-40 scores were significantly higher and the total operation time was longer in the spinal anaesthesia group (median score: 194.5 vs. 179.0, p<0.001 and mean +/- SD: 69.0 +/- 13.3 vs. 62.7 +/- 13.4 minutes, p=0.02, respectively). There was no significant difference in VAS and NRS scores between the groups. Conclusion: Both spinal anaesthesia and general anaesthesia have advantages and disadvantages in terms of emergency caesarean deliveries. Spinal anaesthesia speeds up the recovery time and enables the mother to return to normal life earlier, while general anaesthesia has a short initiation time and does not affect patient satisfaction.
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    Effects of conventional vs high-dose rocuronium on the QTc interval during anesthesia induction and intubation in patients undergoing coronary artery surgery: a randomized, double-blind, parallel trial
    Öztürk, T; Agdanli, D; Bayturan, Ö; Çikrikci, C; Keles, GT
    Myocardial ischemia, as well as the induction agents used in anesthesia, may cause corrected QT interval (QTc) prolongation. The objective of this randomized, double-blind trial was to determine the effects of high-vs conventional-dose bolus rocuronium on QTc duration and the incidence of dysrhythmias following anesthesia induction and intubation. Fifty patients about to undergo coronary artery surgery were randomly allocated to receive conventional-dose (0.6 mg/kg, group C, n=25) or high-dose (1.2 mg/kg, group H, n=25) rocuronium after induction with etomidate and fentanyl. QTc, heart rate, and mean arterial pressure were recorded before induction (T0), after induction (T1), after rocuronium (just before laryngoscopy; T2), 2 min after intubation (T3), and 5 min after intubation (T4). The occurrence of dysrhythmias was recorded. In both groups, QTc was significantly longer at T3 than at baseline [475 vs 429 ms in group C (P=0.001), and 459 vs 434 ms in group H (P=0.005)]. The incidence of dysrhythmias in group C (28%) and in group H (24%) was similar. The QTc after high-dose rocuronium was not significantly longer than after conventional-dose rocuronium in patients about to undergo coronary artery surgery who were induced with etomidate and fentanyl. In both groups, compared with baseline, QTc was most prolonged at 2 min after intubation, suggesting that QTc prolongation may be due to the nociceptive stimulus of intubation.
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    The effect of epidural and general anesthesia on newborn rectal temperature at elective cesarean section
    Yentur, EA; Topcu, I; Ekici, Z; Ozturk, T; Keles, GT; Civi, M
    Both epidural and general anesthesia can impair thermoregulatory mechanisms during surgery. However, there is lack of information about the effects of different methods of anesthesia on newborn temperature. The purpose of this study was to determine whether there are differences in newborn rectal temperature related to type of anesthesia. Sixty-three pregnant women were randomly assigned to receive general or epidural anesthesia. Maternal core temperature was measured three times with a rectal probe just before anesthesia, at the beginning of surgery and at delivery. In addition, umbilical vein blood was sampled for pH. The rectal temperatures of the babies were recorded immediately after delivery, and Apgar scores were determined 1, 5, and 10 min after birth. The duration of anesthesia and the volume of intravenous fluid given during the procedure (833 +/- 144 vs 420 +/- 215 mL) were significantly higher in the epidural group than in the general anesthesia group (P < 0.0001). Maternal rectal temperatures were not different in both groups at all measurements. In contrast, newborn rectal temperatures were lower in the epidural anesthesia group than in the general anesthesia group (37.4 +/- 0.3 vs 37.6 +/- 0.3 degrees C; P < 0.05) immediately after birth. Furthermore, the umbilical vein pH value (7.31 +/- 0.05 vs 7.33 +/- 0.01; P < 0.05) and Apgar scores at the 1st-min measurement (8.0 +/- 0.9 vs 8.5 +/- 0.7; P < 0.05) were lower in the epidural anesthesia group than in the general anesthesia group. Since epidural anesthesia requires more iv fluid infusion and a longer time for cesarean section, it involves a risk of a mild temperature reduction for the baby which, however, did not reach the limits of hypothermia.
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    Assessment of in-hospital cardiopulmonary resuscitation using Utstein template in a university hospital
    Tok, D; Keles, GT; Toprak, V; Topcu, I
    The aim of this study was to evaluate the effectiveness of in-hospital cardiopulmonary resuscitation (CPR) strategies and identify key predictors of post-CPR survival in a university hospital setting. Using a form recommended by the European Resuscitation Council, data regarding in-hospital CPR attempts from January 2001 to December 2002 were recorded and analyzed. The main outcomes of interest were immediate survival after CPR and survival to hospital discharge. Of 307 patients who suffered cardiac arrest in the study period, 103 (33.5%) were resuscitated. Of these 103 patients, 28 (27.2%) survived immediately and 12 (11.7%) survived to hospital discharge. The key predictors of immediate survival were CPR duration and initial cardiac rhythm as monitored by ventricular fibrillation/pulseless ventricular tachycardia (VF/VT). The key predictors of survival to hospital discharge were CPR duration, immediate defibrillation, Glasgow Coma Scale score, and Early Prediction Score. Together, our results suggest that in-hospital CPR strategies require improvement. They also underscore the importance of data collection and analysis in evaluating the effectiveness of inhospital CPR strategies.
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    Comparison of antimicrobial effects of dexmedetomidine and etomidate-lipuro with those of propofol and midazolam
    Keles, GT; Kurutepe, S; Tok, D; Gazi, H; Dinç, G
    Background and objectives: The aim of our study was to investigate the antimicrobial effects of dexmedetomidine and etomidate-lipuro, and to compare these effects with those of midazolam and propofol on Staphylococcus aureus, Escherichia coli, Pseudomonas aeroginosa, Acinetobacter baumannii and extended-spectrum beta-lactamase Escherichia coli (E. coli ESBL). Methods: All hypnotic dilutions were exposed to micro-organisms for 0, 30, 60, 120 and 240 min at room temperature in vitro. The inoculums taken from diluted suspensions were re-inoculated on blood agar and incubated for 18-24 h at 35 degrees C after which a count of the colonies was compared. Results: Midazolam reduced the viable cells of S. aureus at 30, 60, 120 and 240 min, and also completely inhibited the growth of E. coli, R aeroginosa, A. baumannii and E. coli ESBL. Dexmedetomidine, etomidate-lipuro and propofol, however, did not inhibit any of the micro-organisms tested. Conclusion: In vitro, midazolam had an antimicrobial effect on E. coli, P aeroginosa, A. baumannii and E. coli ESBL. Like propofol and dexmedetomidine, etomidate-lipuro had no antimicrobial effect on any of the micro-organisms tested.
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    Evaluation of piroxicam-β-cyclodextrin as a preemptive analgesic in functional endoscopic sinus surgery
    Keles, GT; Topçu, I; Ekici, Z; Yentür, A
    The preemptive analgesic efficacy and adverse effects of preoperatively administered piroxicam-beta-cyclodextrin for post-endoscopic sinus surgery pain was determined in a prospective, double-blind, randomized, clinical study. Seventy-five American Society of Anesthesiologists status I-II patients, aged 18-65 years, were divided into three groups with similar demographic characteristics: group 1 received 20 mg piroxicam-beta-cyclodextrin, group 2 received 40 mg piroxicam-beta-cyclodextrin and group 3 received placebo orally before induction of general anesthesia. A blinded observer recorded the incidence and severity of pain at admission to the post-anesthesia care unit (PACU), at 15, 30, and 45 min in the PACU, and 1, 2, 4, 6, and 24 h postoperatively. All patients received patient-controlled morphine analgesia during the postoperative period and consumption was recorded for 24 h. During the PACU period, mean visual analogue scale values were significantly lower in groups 1 and 2 compared to group 3 (P < 0.05). During the postoperative period, morphine consumption was 3.03 +/- 2.54, 2.7 +/- 2.8, and 5.56 +/- 3.12 mg for each group, respectively (P < 0.05). As a side effect, bleeding was observed in groups 1 and 3, nausea and vomiting in all groups, and edema only in group 3. However, no significant differences were detected in any of the parameters analyzed, which also included epigastric pain, constipation/diarrhea and headache. Similar hematological test results were obtained for all groups. Preemptive administration of piroxicam-beta-cyclodextrin effectively reduced analgesic consumption, and 40 mg of the drug was more effective than 20 mg piroxicam-beta-cyclodextrin without side effects during the postoperative period.
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    Basic life support skills of doctors in a hospital resuscitation team
    Tok, D; Keles, GT; Tasyüz, T; Yentür, EA; Toprak, V
    The aim of the present study was to evaluate the basic life support skills of doctors in a hospital resuscitation team and to identify potential factors affecting those skills. Twelve anesthesiology residents were induced in this study. Each doctor was asked to perform mouth-to-mouth ventilation for 10 minutes and then chest compression for another 10 minutes on a Laerdal Skillmeter Resusci-Anne manikin during the day (10 am) and at night (10 pm). The rates of correct ventilation, correct chest compression, ventilation errors (i.e., excessive inflation, stomach insufflation, insufficient ventilation), and compression errors (i.e., insufficient chest compression/decompression, excessive chest compression, incorrect hand placement) were determined for each 2-min interval up to 10 min. In addition, effects of sex, seniority, CPR duration, and time of day (day vs night) on those skills were assessed. The mean rates of correct ventilation were 53.3+/-23.9% (day) and 60.4+/-16% (night); the mean rates of correct chest compression, 76.9+/-15% (day) and 76.5+/-14.7% (night). During the first 2-minutes period of testing at night, men doctors more frequently achieved correct ventilation than did women doctors (p<0.05). Overall, the practical CPR skills of the study participants were not influenced by sex, seniority, CPR duration, or time of day; however, the participants' skills were poor. This suggests that all medical staff, especially members of in-hospital resuscitation teams, should undergo regular, periodic CPR training.
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    The effect of remifentanil on the emergence characteristics of children undergoing FBO for bronchoalveolar lavage with sevoflurane anaesthesia
    Ozturk, T; Erbuyun, K; Keles, GT; Ozer, M; Yuksel, H; Tok, D
    Background and objective The aim of this study was to compare the effects of sevoflurane vs. sevoflurane and remifentanil on cough and agitation during emergence and recovery after fiberoptic bronchoscopy. Methods Children between 2 and 6 years of age undergoing fiberoptic bronchoscopy were enrolled. All patients were premedicated with oral midazolam. Patients were randomly assigned to either group S (sevoflurane alone, n=25) or group SR (sevoflurane with remifetanil, n=25). Anaesthesia was induced and maintained with sevoflurane in all patients. Group SR received remifentanil at a bolus dose of 1 mu g/kg over 2 min followed by a maintenance infusion of 0.15 mu g/kg/min. In addition to routine anaesthesia documentation, agitation scores and cough scores were recorded every 5 min during emergence and recovery. Results Duration of the procedure, anaesthesia and emergence phases was similar in both groups (P>0.05). Time until recovery was significantly shorter in group SR than in group S (7.0 +/- 5.5 min and 13.0 +/- 3.5 min, respectively; P = 0.001). Cough scores were not significantly different between the two groups during emergence and recovery (Kruskal-Wallis ANOVA test, P>0.05). However, the mean agitation score at 5 min in group SR was significantly higher than that in group S (Kruskal-Wallis ANOVA test, P<0.01). One case of hypoxaemia from thoracic rigidity occurred in a patient in group SR. Conclusion The addition of remifentanil significantly shortened recovery time in children undergoing fiberoptic bronchoscopy under sevoflurane anaesthesia. In the recovery period, remifentanil did not decrease cough, and increased agitation. Eur J Anaesthesiol 26:338-342 (c) 2009 European Society of Anaesthesiology.
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    Homc Care Organization and Ethical Issues
    Keles, GT
    Home health care is the fastest-growing denomination in the medicare program because of the aging population, the increasing prevalence of chronic disease and increasing medical improvement. All the home care patients must be monitoried vital signs in home care conditions. Such as heart rate, ECG, blood pressure, heart rhythm regularity, respiratory rate, oxygen saturation (SpO2), nutrition status, body temperature vital signs are measured, and data are recorded. This medical record is accessible via e-mail, fax or personal. Some medical devices allow healthcare professionals to remotely monitor, diagnose and provide healthcare to patients in their home and work environment. This tecnic is relying on a combination of advanced remote monitoring devices, telecommunication technology and innovative software and hardware solutions to remotely perform vital signs monitoring, evaluation and treatment outside the traditional medical institutions i.e. hospitals and clinics. This paper discusses which health care monitorization and how can evaluate together collaboratively to improve the quality of home care patients resident in care homes.
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    The effect of fentanyl and remifentanil on different recovery scores with sevoflurane and desflurane after ambulatory anaesthesia
    Keles, GT; Toprak, V; Ekici, Z; Tok, D
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    Subcutaneous emphysema following severe vomiting after emerging from general anesthesia
    Toprak, V; Keles, GT; Kaygisiz, Z; Tok, D
    Postoperative nausea and vomiting-related subcutaneous emphysema is an unexpected complication, especially after uneventful surgery and anesthesia. Here we report and discuss two cases of subcutaneous emphysema following severe retching and vomiting which resolved spontaneously after several days.
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    Evaluation of Cardiopulmonary Resuscitation Conditions in Turkey: Current Status of Code Blue
    Keles, GT; Ozbilgin, S; Ugur, L; Birbicer, H; Akin, S; Kuvaki, B; Doruk, N; Türkan, H; Akan, M
    Objective: Globally, previously determined teams activated by 'code blue' calls target rapid and organised responses to medical emergency situations. This study aimed to evaluate the cardiopulmonary resuscitation (CPR) conditions in Turkey. Methods: A web-based survey was sent to anaesthesiologists in Turkey via email. The survey included 36 questions about demographic features and 'code blue' practices and procedures. Results: A total of 180 participants were included. The mean working duration was 16.1 +/- 7.5 years. Of the anaesthesiologists who participated, 35% worked in university, 26.1% in education and research, 1.7% in city hospitals, 18.9% in state hospitals and 18.3% in private hospitals; 68.3% had CPR certification. There were code blue systems in 97.6% of the organisations. For code blue calls, 71.9% were activated by calling '2222'. There were 41.5% organisations with code blue teams of 3-4 people, whereas 26.7% had 2-member teams. Among call responders, 68.5% were anaesthesia technicians/paramedics, 60.7% were anaesthesiologists and 42.7% were anaesthesia assistants. In organisations, 66.3% regularly conducted code blue training. In total, 63.3% of the participants stated that the time to reach the location was nearly 2-4 minutes. During CPR, the use of capnography was 18.3%. Of the participants, 73.8% chose endotracheal intubation as priority airway device during CPR. Conclusion: Today, code blue practice is an important quality criterion for hospitals. This study shows the current status of 'code blue' according to the results of respondent data completing the survey. To prevent in-hospital cardiac arrest, a chain of preventive measures should be established, including personnel training, monitoring of patients, recognition of patient deterioration, the presence of a call for help system and effective intervention.
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    Evaluation of Post-resuscitation Care Practices of Physicians Working in Intensive Care Units
    Özcan, S; Birbiçer, H; Karaaslan, P; Keles, GT; Karahan, MA
    Objective: In this study, it was aimed to evaluate the practices of physicians working in intensive care units about post-resuscitation care in patients whose spontaneous circulation returned with cardiopulmonary resuscitation. Materials and Methods: In this cross-sectional study, a web-based questionnaire containing 28 questions was applied to physicians working in an intensive care units. Results: A total of 118 specialist physicians participated in the study. The mean arterial pressure target after resuscitation was mostly (91.5%) 65-75 mmHg, and the most preferred inotropic agent was noradrenaline (81.2%). It was determined that 52.1% of the participants applied targeted temperature management and continued for 24 h. Neuroprognostic evaluation was performed after 24 h, and most commonly Glasgow coma scale (96.6%), pupillary and corneal reflexes (92.2%), and computerized brain tomography (60.3%) were used. However, it was observed that biomarkers and neurophysiological methods were used less frequently. Conclusion: In this study, it was observed that there were differences in practices according to hospital conditions in post-resuscitation care, but physicians generally followed international guidelines. Simultaneously, it is considered that in addition to the international guidelines, national guidelines are necessary in accordance with the conditions of our country, and training was needed for standard applications.

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