Browsing by Author "Kiliç B."

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    Pupils' attitudes for physical education lesson and science lesson at primary schools: A comparative example of ankara province
    (American-Eurasian Network for Scientific Information, 2014) Korkmaz M.; Yücel A.S.; Kiliç B.; Çatikkaş F.; Tuna D.C.
    The aim of this study is to examine primary school pupils' attitudes for physical education and science lessons in a comparative and applied fashion. Totally (N=452) primary school pupils participated in our study. Participants were selected randomly. In this applied study, a questionnaire with 5-point likert scale that consisted of two parts for the two lessons was administrated. Data as a result of the study were subject to reliability analysis, and the Cronbach Alpha coefficient was found as 0.921. Kaiser-MeyerOlkin, Barlett's Test of Sphericity analysis, Scree Plotgraph, Factor analysis, Correlation analysis, Tukey, and t-test were applied. It was found that the research was meaningful with Item-Total correlations having a p<0.01 significance level. As a result of the study, it was found that participants performed greater attitudes and importance for science, displayed higher interest and attention towards science lessons, and had thoughts that they will need science lessons more in the future. As for their attitudes for physical education lesson, it was seen that they were lower than those for science lessons. Among the main reasons are ideas and opinions that pupils do insufficient sports activities, sports equipment and materials are insufficient, and sports areas are ineligible for the types they wish to do. © 2014 AENSI Publisher All rights reserved.
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    Carpal tunnel syndrome
    (American-Eurasian Network for Scientific Information, 2015) Kiliç B.; Yücel A.S.; Yaman Ç.; Çatikkas F.; Hergüner G.
    Carpal tunnel syndrome is the most common periphery nerve-trapping syndrome. CTS (Carpal Tunnel Syndrome) surgery is the most often operation around the world. Carpal tunnel syndrome occurs as a result of nerve compression at wrist level and generally appears with affective and motor findings. This symptom is also called hand acroparesthesia, tenar palsy, tardy median palsy, median neuritis, median tenar neuritis and so on. It is seen more in adult females over the age of 40. First symptoms are generally burn up, hyperkinesia, weakness, pain, pins and needles, or loss of sense that occur in the area where median nerve is eligible for bilateral spread on hand. Neuronal conduction and electrodiagnostic examinations including needle electromyography are the most common auxiliary methods used for diagnosis. Treatment procedures are generally divided into two, being conservative and surgery. Most commonly applied method is open surgical release. In our study, we shared the perfect results obtained from 186 patients with carpal tunnel syndrome whom we applied surgery under local anesthesia without admission to the hospital and we followed up from outpatient clinics. We also showed that with a practical method as we applied, patients could return their social and work lives within a short period of time. © 2015 AENSI Publisher All rights reserved.
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    Shared Biological Pathways and Processes in Patients with Intellectual Disability: A Multicenter Study
    (Georg Thieme Verlag, 2022) Günay Ç.; Aykol D.; Özsoy Ö.; Sönmezler E.; Hanci Y.S.; Kara B.; Akkoyunlu Sünnetçi D.; Cine N.; Deniz A.; Özer T.; Ölçülü C.B.; Yilmaz Ö.; Kanmaz S.; Yilmaz S.; Tekgül H.; Yildiz N.; Acar Arslan E.; Cansu A.; Olgaç Dündar N.; Kusgoz F.; Didinmez E.; Gençpinar P.; Aksu Uzunhan T.; Ertürk B.; Gezdirici A.; Ayaz A.; Ölmez A.; Ayanoǧlu M.; Tosun A.; Topçu Y.; Kiliç B.; Aydin K.; Çaǧlar E.; Ersoy Kosvali Ö.; Okuyaz Ç.; Besen Ş.; Tekin Orgun L.; Erol İ.; Yüksel D.; Sezer A.; Atasoy E.; Toprak Ü.; Güngör S.; Ozgor B.; Karadaǧ M.; Dilber C.; Şahinoǧlu B.; Uyur Yalçin E.; Eldes Hacifazlioglu N.; Yaramiś A.; Edem P.; Gezici Tekin H.; Yilmaz Ü.; Ünalp A.; Turay S.; Biçer D.; Gül Mert G.; Dokurel Çetin İ.; Kirik S.; Öztürk G.; Karal Y.; Sanri A.; Aksoy A.; Polat M.; Özgün N.; Soydemir D.; Sarikaya Uzan G.; Ülker Üstebay D.; Gök A.; Yeśilmen M.C.; Yiś U.; Karakülah G.; Bursali A.; Oktay Y.; Hiz Kurul S.
    Background  Although the underlying genetic causes of intellectual disability (ID) continue to be rapidly identified, the biological pathways and processes that could be targets for a potential molecular therapy are not yet known. This study aimed to identify ID-related shared pathways and processes utilizing enrichment analyses. Methods  In this multicenter study, causative genes of patients with ID were used as input for Disease Ontology (DO), Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes enrichment analysis. Results  Genetic test results of 720 patients from 27 centers were obtained. Patients with chromosomal deletion/duplication, non-ID genes, novel genes, and results with changes in more than one gene were excluded. A total of 558 patients with 341 different causative genes were included in the study. Pathway-based enrichment analysis of the ID-related genes via ClusterProfiler revealed 18 shared pathways, with lysine degradation and nicotine addiction being the most common. The most common of the 25 overrepresented DO terms was ID. The most frequently overrepresented GO biological process, cellular component, and molecular function terms were regulation of membrane potential, ion channel complex, and voltage-gated ion channel activity/voltage-gated channel activity, respectively. Conclusion  Lysine degradation, nicotine addiction, and thyroid hormone signaling pathways are well-suited to be research areas for the discovery of new targeted therapies in ID patients. © 2022 Hippokrates Verlag GmbH. All rights reserved.