Browsing by Author "Kirkim G."

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    Results of factorial validity and reliability of the international outcome inventory for hearing aids in Turkish
    (2009) Serbetcioglu B.; Mutlu B.; Kirkim G.; Uzunoglu S.
    Objective; The International Outcome Inventory for Hearing Aids (IOI-HA) with seven-item questionnaire is used to evaluate the effectiveness of audiological rehabilitation programme utilizing hearing aids. Factor analysis of the subscales of the IOI-HA has been previously reported for English and Dutch translations, but not for the Turkish Language. Thus, the main objective of this study was to evaluate the internal consistency and factorial (construct) validity of the IOI-HA that was translated to Turkish. Materials & Methods; Participants were 45 hearing impaired adults (23 male, 22 female) who were included in audiological rehabilitation programme between January 2006 and June 2007. The study was performed in tertiary referral center, Dokuz Eylül University, Medical School, Department of Otolaryngology. The mean age of subjects was 64.15 ± 13.8 years. Average pure-tone thresholds at frequencies of 0.5, 1 and 2 kHz (PTA1) of the aided ear were ranged from 33 dB HL to 78 dB HL with a mean of 51.7 * 10.1 dB HL. Mean speech discrimination score was 70.2%±18.08. Forty-five adult patients were evaluated by using IOI-HA as a part of the audiological rehabilitation programme. Results; The factor analysis yielded strong support for a unifactorial structure of the scale, and a high internal consistency of the inventory (p<0.05) (Cronbach's alpha value were found to be 0.773 at first month and 0.783 at sixth month). It is interpreted that the IOI-HA translated to Turkish has enough reliability and factorial validity. Conclusion; This version can be used in the evaluation of the hearing aid satisfaction in Turkish hearing impaired population. Copyright 2005 © The Mediterranean Society of Otology and Audiology.
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    Effect of erythropoietin on acoustically traumatized rat cochlea an immunohistochemical study
    (Science Printers and Publishers Inc., 2014) Gürgen O.; Gürgen S.G.; Kirkim G.; Kolatan E.; Gürkan S.; Güvenç Y.; Eskiizmir G.
    Objective: To investigate the audiological and histopathological effects of erythropoietin on acoustic overstimulation in rats. Study design: Twenty-two male Wistar albino rats were divided into 3 groups: sham group (n=7), erythropoietin injection group (n = 8), and saline injection group (n=7). Both erythropoietin and saline injection groups were exposed to white noise (100 decibel [dB] sound pressure level [SPL]) for 3 hours. Auditory brainstem responses were measured before, immediately after, and on the 7th day of noise exposure. All animals were sacrificed on the 7th day and temporal bones were collected. The serial sections of the cochleae were stained by caspase-3 and caspase-9 immunostaining and by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) method in order to detect apoptotic cells. Results: In the saline group statistically significant differences were detected between the baseline and immediate postacoustic overstimulation thresholds of click and 6 kHz stimuli. However, when the baseline and immediate postacoustic overstimulation thresholds of click and 6 kHz stimuli were compared in the erythropoietin injection group, no statistically significant difference was determined. Histopathologic evaluations demonstrated that erythropoietin decreased the amount of apoptotic cells in the cochlea. Conclusion: Erythropoietin is likely to prevent the acute threshold changes and decrease the amount of apoptosis in cochlea after acoustic overstimulation in rats. © Science Printers and Publishers, Inc.